Skip to content
Disclosery

SEPN SEPTERNA INC

Follow

Stock (common), issuer CIK 1984086

81 managers (82 13F filers) reported a position in SEPN shares at 2025-09-30, 44,549,033 shares in all. 10 filers opened a position and 16 filers sold out during the quarter.

Managers
81
13F filers
82
New
10
Added
31
Reduced
17
Sold out
16
Shares held by filers
44,549,033

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.6,995,858$132M1.62%013F-HRTimelineGroup
TRV GP V, LLC6,215,591$117M33.07%013F-HRTimeline
Driehaus Capital Management LLC4,919,896$92.5M0.66%+239,46513F-HRTimeline
TRV GP VI, LLC4,211,659$79.2M72.26%013F-HRTimeline
BVF INC/ILin group BVF INC/IL4,015,790$75.5M3.06%-380,33413F-HRTimelineGroup
SAMSARA BIOCAPITAL, LLC3,149,128$59.2M7.73%013F-HRTimeline
Siren, L.L.C.in group Siren, L.L.C.2,202,514$41.4M1.62%013F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC1,518,757$28.6M<0.01%+104,39413F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.1,459,795$27.5M<0.01%+68,99513F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC1,454,720$27.4M<0.01%+38,40613F-HRTimelineGroup
Avoro Capital Advisors LLC1,337,500$25.2M0.33%+100,00013F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC1,176,491$22.1M2.19%+329,26413F-HRTimelineGroup
Venrock Adviser, LLC610,808$11.5M0.65%+70,35513F-HRTimeline
Casdin Capital, LLC553,268$10.4M0.87%013F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC545,701$10.3M<0.01%+57,74513F-HRTimelineGroup
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC541,450$10.2M0.29%013F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP418,960$7.88M<0.01%+48,96813F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC384,200$7.23M0.01%+332,25613F-HRTimelineGroup
Catalio Capital Management, LP294,360$5.54M1.02%013F-HRTimeline
Checkpoint Capital L.P.283,158$5.33M1.78%-303,31513F-HRTimeline
Woodline Partners LP282,585$5.32M0.03%013F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …222,702$4.19M0.01%013F-HRTimelineGroup
Sio Capital Management, LLC189,199$3.56M0.9%-395,23613F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co186,904$3.52M<0.01%+32,12313F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.177,070$3.33M<0.01%+165,23713F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP167,345$3.15M<0.01%+13,00113F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding113,034$2.13M+35,392Timeline
Rangeley Capital, LLC88,000$1.66M1.55%+29,39513F-HRTimeline
Logos Global Management LP83,548$1.57M0.16%-25,65413F-HRTimeline
Walleye Capital LLCin group Walleye Capital LLC80,341$1.51M0.01%new13F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding59,046$1.11M-41,989Timeline
Longaeva Partners L.P.57,064$1.07M0.23%new13F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY54,458$1.02M<0.01%-30,40213F-HR/ATimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp51,631$971K<0.01%+3,14213F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/51,495$969K<0.01%-47,71813F-HR/ATimelineGroup
JACOBS LEVY EQUITY MANAGEMENT, INC35,778$673K<0.01%new13F-HRTimeline
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.35,000$658K<0.01%013F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC30,102$566K<0.01%-5,60413F-HR/ATimelineGroup
RHUMBLINE ADVISERS27,604$519K<0.01%-96813F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/27,424$516K<0.01%+2,52213F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC25,283$476K<0.01%new13F-HRTimelineGroup
Nuveen, LLCin group TIAA23,961$451K<0.01%-34,01013F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.22,100$416K<0.01%013F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN20,147$379K<0.01%+5,43013F-HRTimelineGroup
Verition Fund Management LLC20,131$379K<0.01%new13F-HRTimeline
Soleus Capital Management, L.P.18,260$343K0.02%-57,19613F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\14,135$266K<0.01%+2,01213F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…13,685$257K<0.01%013F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.12,863$242K<0.01%+12,64913F-HRTimelineGroup
PharVision Advisers, LLC11,932$224K0.13%+1,78013F-HRTimeline
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.in group Mirae Asset Global Investment…9,791$184K<0.01%-1,90613F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO8,736$164K<0.01%-1,36513F-HR/ATimelineGroup
Police & Firemen's Retirement System of…5,175$97.3K<0.01%+1,62013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS4,155$78.2K<0.01%+1,94513F-HRTimelineGroup
Covestor Ltd3,620$68K0.04%+1,29613F-HRTimeline
FMR LLCin group FMR LLC3,438$64.7K<0.01%+95313F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND2,900$54.5K<0.01%013F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc1,945$36.6K<0.01%013F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…1,944$36.6K<0.01%013F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…1,896$35.7K<0.01%new13F-HRTimelineGroup
Quarry LP1,736$32.7K0.01%-1,86513F-HRTimeline
GROUP ONE TRADING LLC1,689$31.8K<0.01%+90013F-HRTimeline
Sterling Capital Management LLC1,475$27.7K<0.01%+89813F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…1,371$25.8K<0.01%+113F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA1,083$20K<0.01%-75713F-HRTimelineGroup
SIGNATUREFD, LLC966$18.2K<0.01%013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…959$18K<0.01%-1,26613F-HRTimelineGroup
CWM, LLCin group CWM, LLC884$17K<0.01%+1213F-HRTimelineGroup
GAMMA Investing LLC804$15.1K<0.01%+22713F-HRTimeline
AMALGAMATED BANK634$12K<0.01%013F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\265$4.99K<0.01%013F-HRTimelineGroup
Versant Capital Management, Inc261$4.91K<0.01%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC249$4.68K<0.01%-6,92413F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…198$3.72K<0.01%new13F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC143$2.69K<0.01%013F-HRTimeline
Fortitude Family Office, LLC71$1.34K<0.01%013F-HRTimeline
Arax Advisory Partners63$1.19K<0.01%new13F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…63$1.19K<0.01%+4113F-HRTimelineGroup
SBI Securities Co., Ltd.50$941<0.01%013F-HRTimeline
ROTHSCHILD INVESTMENT LLC30$564<0.01%013F-HRTimeline
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/8$150<0.01%013F-HRTimelineGroup