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Disclosery

SEPN SEPTERNA INC

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Stock (common), issuer CIK 1984086

72 managers (72 13F filers) reported a position in SEPN shares at 2024-12-31, 44,129,388 shares in all. 68 filers opened a position and 0 filers sold out during the quarter.

Managers
72
13F filers
72
New
68
Added
0
Reduced
0
Sold out
0
Shares held by filers
44,129,388

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2024

Filers in the available 13F reports with a share position at 2024-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.6,995,858$160M2.13%new13F-HRTimelineGroup
TRV GP V, LLC6,215,591$142M48.42%13F-HRTimeline
TRV GP VI, LLC3,152,456$72.2M61.75%13F-HRTimeline
SAMSARA BIOCAPITAL, LLC2,768,520$63.4M8.7%new13F-HRTimeline
Driehaus Capital Management LLC2,589,553$59.3M0.49%new13F-HRTimeline
BVF INC/ILin group BVF INC/IL2,452,024$56.2M1.9%new13F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.2,202,514$50.4M2.23%new13F-HRTimelineGroup
Deep Track Capital, LP1,912,929$43.8M1.64%new13F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.1,677,135$38.4M<0.01%new13F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC1,674,357$38.3M0.01%new13F-HRTimelineGroup
Avoro Capital Advisors LLC1,110,000$25.4M0.36%new13F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson1,096,302$25.1M0.01%new13F-HRTimelineGroup
Catalio Capital Management, LP1,024,245$23.5M5.13%13F-HRTimeline
FMR LLCin group FMR LLC1,002,958$23M<0.01%new13F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC985,032$22.6M<0.01%new13F-HRTimelineGroup
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…861,814$19.7M0.38%new13F-HRTimelineGroup
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC750,000$17.2M0.48%new13F-HRTimelineGroup
Soleus Capital Management, L.P.675,409$15.5M1.17%new13F-HRTimeline
Cormorant Asset Management, LP560,000$12.8M0.7%new13F-HRTimeline
Casdin Capital, LLC553,268$12.7M0.85%new13F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/518,588$11.9M<0.01%new13F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC404,882$9.27M0.01%new13F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC380,577$8.72M<0.01%new13F-HRTimelineGroup
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…300,000$6.87M0.01%new13F-HRTimelineGroup
Woodline Partners LP300,000$6.87M0.05%new13F-HRTimeline
STATE STREET CORPin group STATE STREET CORP272,776$6.25M<0.01%new13F-HRTimelineGroup
Sio Capital Management, LLC271,687$6.22M1.75%new13F-HRTimeline
ArrowMark Colorado Holdings LLC147,886$3.39M0.05%new13F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP147,776$3.38M<0.01%new13F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co139,616$3.2M<0.01%new13F-HRTimelineGroup
Logos Global Management LP134,202$3.07M0.36%new13F-HRTimeline
UBS Group AGin group UBS Group AG108,453$2.48M<0.01%new13F-HRTimelineGroup
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …102,749$2.35M<0.01%13F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/78,744$1.8M<0.01%new13F-HRTimelineGroup
TD Asset Management Inc69,460$1.59M<0.01%new13F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY41,911$960K<0.01%new13F-HR/ATimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp38,093$872K<0.01%new13F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO38,015$871K<0.01%new13F-HRTimelineGroup
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.35,000$802K<0.01%new13F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC28,785$659K<0.01%new13F-HR/ATimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC26,208$600K<0.01%new13F-HRTimelineGroup
Nuveen Asset Management, LLCin group TIAA23,961$549K<0.01%new13F-HRTimelineGroup
Verition Fund Management LLC22,695$520K<0.01%new13F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …22,095$506K<0.01%new13F-HRTimelineGroup
Lindbrook Capital, LLC21,000$481K0.04%new13F-HRTimeline
Walleye Capital LLCin group Walleye Capital LLC20,204$463K<0.01%new13F-HRTimelineGroup
RHUMBLINE ADVISERS19,995$458K<0.01%new13F-HR/ATimeline
M&T Bank Corpin group M&T Bank Corp16,394$376K<0.01%new13F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC14,633$335K<0.01%new13F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.12,154$278K<0.01%new13F-HRTimelineGroup
OCONNOR, A Distinct Business Unit of UB…12,118$278K0.01%new13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
MetLife Investment Management, LLCin group MetLife Investment Management…11,555$265K<0.01%new13F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN10,651$244K<0.01%new13F-HRTimelineGroup
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.in group Mirae Asset Global Investment…10,519$241K<0.01%new13F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\10,419$239K<0.01%new13F-HR/ATimelineGroup
SOROS FUND MANAGEMENT LLCin group SOROS FUND MANAGEMENT LLC10,000$229K<0.01%new13F-HRTimelineGroup
Zimmer Partners, LP10,000$229K<0.01%new13F-HRTimeline
Corebridge Financial, Inc.in group Corebridge Financial, Inc.9,236$212K<0.01%new13F-HRTimelineGroup
SG Americas Securities, LLC8,095$185K<0.01%new13F-HRTimeline
STRS OHIO3,400$77.9K<0.01%new13F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…2,680$61.4K<0.01%new13F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS2,251$51.5K<0.01%new13F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…1,944$44.5K<0.01%new13F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc1,840$42.1K<0.01%new13F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND1,400$32.1K<0.01%new13F-HR/ATimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA1,398$32K<0.01%new13F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…1,370$31.4K<0.01%new13F-HR/ATimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,093$25K<0.01%new13F-HRTimelineGroup
AMALGAMATED BANK634$15K<0.01%new13F-HRTimeline
Sterling Capital Management LLC266$6.09K<0.01%new13F-HRTimeline
GAMMA Investing LLC15$344<0.01%new13F-HRTimeline
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$00%new13F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.