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RTW INVESTMENTS, LP

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13F filer, CIK 1493215, NEW YORK, NY

RTW INVESTMENTS, LP reported $10,049,752,600 across 88 holdings for the quarter ended 2026-03-31, in a 13F-HR filed 2026-05-15. Its ten largest share positions make up 49.99% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001493215-26-000130

Period
2026-03-31
Reported value
$10B
Holdings
88
Top 10 weight
49.99%
New
9
Sold out
12

Largest buys vs the previous quarter

SecurityShares changeApprox. value
CGONadded+4,972,681$337M
CELCadded+2,489,461$284M
ERASadded+16,010,524$259M
TNGXadded+11,809,392$247M
HNGEadded+1,576,500$60.8M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
PENexited-866,499-$269M
AXSMexited-888,001-$162M
APLSreduced-3,981,719-$160M
PODDexited-324,600-$92.3M
MASIexited-683,294-$88.9M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q1 2026

Share positions as resolved from 13F-HR 0001493215-26-000130, largest first. % of portfolio is the value over $10,049,752,600, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
MDGLMADRIGAL PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 1,993,687 shares; 2024Q4: 1,993,687 shares; 2025Q1: 1,993,687 shares; 2025Q2: 1,993,687 shares; 2025Q3: 1,993,687 shares; 2025Q4: 1,993,687 shares; 2026Q1: 1,993,687 shares 1,993,687$1.04B10.38%0Timeline
INSMINSMED INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 3,272,008 shares; 2024Q4: 3,014,558 shares; 2025Q1: 3,014,558 shares; 2025Q2: 3,084,558 shares; 2025Q3: 3,084,558 shares; 2025Q4: 4,842,879 shares; 2026Q1: 4,842,880 shares 4,842,880$792M7.88%+1Timeline
PTGXPROTAGONIST THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 5,426,112 shares; 2024Q4: 5,498,545 shares; 2025Q1: 5,719,415 shares; 2025Q2: 5,756,277 shares; 2025Q3: 5,756,277 shares; 2025Q4: 5,059,053 shares; 2026Q1: 5,059,053 shares 5,059,053$533M5.31%0Timeline
PTCTPTC THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 7,393,127 shares; 2024Q4: 7,393,127 shares; 2025Q1: 7,483,127 shares; 2025Q2: 7,746,415 shares; 2025Q3: 7,746,415 shares; 2025Q4: 7,746,415 shares; 2026Q1: 7,746,415 shares 7,746,415$528M5.25%0Timeline
ARGXARGENX SEQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 654,430 shares; 2024Q4: 673,497 shares; 2025Q1: 673,497 shares; 2025Q2: 673,497 shares; 2025Q3: 673,497 shares; 2025Q4: 673,497 shares; 2026Q1: 709,446 shares 709,446$518M5.16%+35,949Timeline
CGONCG ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 1,344,074 shares; 2024Q4: 1,701,216 shares; 2025Q1: 1,701,216 shares; 2025Q2: 1,701,216 shares; 2025Q3: 1,701,216 shares; 2025Q4: 2,012,127 shares; 2026Q1: 6,984,808 shares 6,984,808$473M4.7%+4,972,681Timeline
CELCCELCUITY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 550,160 shares; 2026Q1: 3,039,621 shares 3,039,621$347M3.45%+2,489,461Timeline
TNGXTANGO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,491,228 shares; 2026Q1: 13,300,620 shares 13,300,620$278M2.77%+11,809,392Timeline
ERASERASCA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 146,651 shares; 2026Q1: 16,157,175 shares 16,157,175$261M2.6%+16,010,524Timeline
NTRANATERA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 2,593,323 shares; 2024Q4: 2,593,323 shares; 2025Q1: 2,593,546 shares; 2025Q2: 2,593,645 shares; 2025Q3: 2,000,000 shares; 2025Q4: 1,500,000 shares; 2026Q1: 1,250,000 shares 1,250,000$250M2.49%-250,000Timeline
RDNTRADNET INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 1,808,604 shares; 2024Q4: 1,978,582 shares; 2025Q1: 2,317,582 shares; 2025Q2: 2,690,344 shares; 2025Q3: 2,815,544 shares; 2025Q4: 3,938,500 shares; 2026Q1: 4,285,000 shares 4,285,000$239M2.38%+346,500Timeline
TARSTARSUS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 3,412,486 shares; 2024Q4: 3,236,549 shares; 2025Q1: 3,316,032 shares; 2025Q2: 3,111,680 shares; 2025Q3: 3,177,436 shares; 2025Q4: 3,335,320 shares; 2026Q1: 3,346,025 shares 3,346,025$235M2.34%+10,705Timeline
APGEAPOGEE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 2,712,096 shares; 2024Q4: 2,712,097 shares; 2025Q1: 2,712,097 shares; 2025Q2: 2,712,097 shares; 2025Q3: 2,712,097 shares; 2025Q4: 2,712,097 shares; 2026Q1: 2,782,097 shares 2,782,097$234M2.33%+70,000Timeline
SYRESPYRE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 3,258,360 shares; 2024Q4: 3,621,996 shares; 2025Q1: 3,621,996 shares; 2025Q2: 3,621,996 shares; 2025Q3: 3,621,996 shares; 2025Q4: 4,171,996 shares; 2026Q1: 4,171,996 shares 4,171,996$210M2.09%0Timeline
COGTCOGENT BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 3,467,486 shares; 2025Q4: 7,592,241 shares; 2026Q1: 5,458,675 shares 5,458,675$210M2.09%-2,133,566Timeline
IRTCIRHYTHM HOLDINGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,181,990 shares; 2026Q1: 1,668,500 shares 1,668,500$197M1.96%+486,510Timeline
STOKSTOKE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 4,652,285 shares; 2024Q4: 5,123,525 shares; 2025Q1: 5,123,525 shares; 2025Q2: 5,123,525 shares; 2025Q3: 5,123,525 shares; 2025Q4: 5,546,856 shares; 2026Q1: 5,623,525 shares 5,623,525$183M1.82%+76,669Timeline
CYTKCYTOKINETICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 2,721,158 shares; 2024Q4: 2,721,158 shares; 2025Q1: 2,721,158 shares; 2025Q2: 2,721,158 shares; 2025Q3: 2,721,158 shares; 2025Q4: 2,721,158 shares; 2026Q1: 2,721,158 shares 2,721,158$179M1.78%0Timeline
ACADACADIA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 13,707,506 shares; 2024Q4: 8,705,501 shares; 2025Q1: 8,540,117 shares; 2025Q2: 8,995,547 shares; 2025Q3: 7,144,524 shares; 2025Q4: 7,144,524 shares; 2026Q1: 7,144,524 shares 7,144,524$159M1.58%0Timeline
ESTAESTABLISHMENT LABS HLDGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 2,645,703 shares; 2024Q4: 2,569,687 shares; 2025Q1: 2,583,887 shares; 2025Q2: 2,584,131 shares; 2025Q3: 2,588,831 shares; 2025Q4: 2,588,831 shares; 2026Q1: 2,655,695 shares 2,655,695$151M1.5%+66,864Timeline
APLSAPELLIS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 7,666,764 shares; 2026Q1: 3,685,045 shares 3,685,045$148M1.48%-3,981,719Timeline
IMCRIMMUNOCORE HLDGS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 4,869,798 shares; 2024Q4: 4,869,798 shares; 2025Q1: 4,869,798 shares; 2025Q2: 4,869,798 shares; 2025Q3: 4,869,798 shares; 2025Q4: 4,869,798 shares; 2026Q1: 4,869,798 shares 4,869,798$147M1.46%0Timeline
RGENREPLIGEN CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,064,000 shares; 2026Q1: 1,206,000 shares 1,206,000$142M1.41%+142,000Timeline
NBIXNEUROCRINE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 1,062,072 shares; 2025Q3: 1,062,072 shares; 2025Q4: 1,062,072 shares; 2026Q1: 1,062,072 shares 1,062,072$140M1.39%0Timeline
GHGUARDANT HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 856,501 shares; 2025Q3: 1,481,033 shares; 2025Q4: 1,481,033 shares; 2026Q1: 1,481,033 shares 1,481,033$137M1.36%0Timeline
IMTXIMMATICS N.VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 10,000,000 shares; 2024Q4: 6,540,540 shares; 2025Q1: 6,909,510 shares; 2025Q2: 6,970,152 shares; 2025Q3: 8,815,617 shares; 2025Q4: 11,433,354 shares; 2026Q1: 12,869,340 shares 12,869,340$127M1.26%+1,435,986Timeline
ZLABZAI LAB LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 2,509,119 shares; 2025Q1: 3,136,680 shares; 2025Q2: 5,536,876 shares; 2025Q3: 2,291,372 shares; 2025Q4: 6,959,032 shares; 2026Q1: 6,574,032 shares 6,574,032$124M1.23%-385,000Timeline
BLTEBELITE BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 312,500 shares; 2025Q4: 715,332 shares; 2026Q1: 715,332 shares 715,332$114M1.13%0Timeline
ISRGINTUITIVE SURGICAL INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 202,456 shares; 2025Q2: 202,456 shares; 2025Q3: 202,456 shares; 2025Q4: 101,228 shares; 2026Q1: 220,000 shares 220,000$101M1.01%+118,772Timeline
ORKAORUKA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 1,850,648 shares; 2024Q4: 1,945,649 shares; 2025Q1: 1,945,649 shares; 2025Q2: 1,945,649 shares; 2025Q3: 1,945,649 shares; 2025Q4: 2,058,148 shares; 2026Q1: 2,058,148 shares 2,058,148$101M1%0Timeline
GHRSGH RESEARCH PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 3,327,129 shares; 2024Q4: 3,327,129 shares; 2025Q1: 5,499,769 shares; 2025Q2: 5,540,457 shares; 2025Q3: 5,569,564 shares; 2025Q4: 5,933,815 shares; 2026Q1: 5,933,815 shares 5,933,815$83.4M0.83%0Timeline
XNCRXENCOR INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 575,000 shares; 2024Q4: 2,402,883 shares; 2025Q1: 2,402,883 shares; 2025Q2: 2,402,883 shares; 2025Q3: 6,221,054 shares; 2025Q4: 6,777,461 shares; 2026Q1: 6,777,461 shares 6,777,461$81.7M0.81%0Timeline
URGNUROGEN PHARMA LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 3,787,347 shares; 2024Q4: 3,834,794 shares; 2025Q1: 3,834,794 shares; 2025Q2: 4,543,895 shares; 2025Q3: 4,543,895 shares; 2025Q4: 4,543,895 shares; 2026Q1: 4,543,895 shares 4,543,895$81.7M0.81%0Timeline
CNTACENTESSA PHARMACEUTICALS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 50,000 shares; 2024Q4: 50,000 shares; 2025Q1: 50,000 shares; 2025Q2: 1,529,836 shares; 2025Q3: 2,291,747 shares; 2025Q4: 1,790,837 shares; 2026Q1: 2,054,175 shares 2,054,175$81.6M0.81%+263,338Timeline
IMVTIMMUNOVANT INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 530,614 shares; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 3,177,850 shares; 2026Q1: 3,177,849 shares 3,177,849$78.9M0.79%-1Timeline
RAREULTRAGENYX PHARMACEUTICAL INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 1,968,002 shares; 2024Q4: 1,968,002 shares; 2025Q1: 1,707,402 shares; 2025Q2: 1,707,402 shares; 2025Q3: 3,258,266 shares; 2025Q4: 3,000,139 shares; 2026Q1: 3,648,795 shares 3,648,795$76.4M0.76%+648,656Timeline
HNGEHINGE HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 353,500 shares; 2026Q1: 1,930,000 shares 1,930,000$74.4M0.74%+1,576,500Timeline
CSTLCASTLE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 2,115,237 shares; 2026Q1: 2,758,335 shares 2,758,335$67.7M0.67%+643,098Timeline
RCKTROCKET PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 17,687,772 shares; 2024Q4: 17,687,772 shares; 2025Q1: 17,687,772 shares; 2025Q2: 17,687,772 shares; 2025Q3: 17,687,772 shares; 2025Q4: 17,687,772 shares; 2026Q1: 17,687,772 shares 17,687,772$63.3M0.63%0Timeline
TSHATAYSHA GENE THERAPIES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 14,946,420 shares; 2024Q4: 8,672,630 shares; 2025Q1: 18,787,866 shares; 2025Q2: 25,021,584 shares; 2025Q3: 24,354,291 shares; 2025Q4: 16,398,297 shares; 2026Q1: 13,680,248 shares 13,680,248$61.2M0.61%-2,718,049Timeline
ALKSALKERMES PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 6,654,033 shares; 2024Q4: 7,557,835 shares; 2025Q1: 6,884,698 shares; 2025Q2: 4,682,289 shares; 2025Q3: 1,672,356 shares; 2025Q4: 1,672,356 shares; 2026Q1: 1,672,356 shares 1,672,356$59.1M0.59%0Timeline
CMPSCOMPASS PATHWAYS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 3,098,987 shares; 2025Q1: 5,538,168 shares; 2025Q2: 8,221,929 shares; 2025Q3: 8,707,390 shares; 2025Q4: 8,757,390 shares; 2026Q1: 10,632,390 shares 10,632,390$58.8M0.59%+1,875,000Timeline
KODKODIAK SCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,487,933 shares; 2026Q1: 1,487,934 shares 1,487,934$56.7M0.56%+1Timeline
REPLREPLIMUNE GROUP INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 1,133,787 shares; 2024Q4: 2,065,010 shares; 2025Q1: 2,065,010 shares; 2025Q2: 2,065,010 shares; 2025Q3: 6,395,732 shares; 2025Q4: 7,140,352 shares; 2026Q1: 7,356,916 shares 7,356,916$56.3M0.56%+216,564Timeline
CRNXCRINETICS PHARMACEUTICALS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 467,000 shares; 2025Q3: 872,387 shares; 2025Q4: 1,351,326 shares; 2026Q1: 1,451,326 shares 1,451,326$52.7M0.52%+100,000Timeline
QUREUNIQURE NVQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 10,000 shares; 2024Q4: 903,625 shares; 2025Q1: 4,265,428 shares; 2025Q2: 5,158,231 shares; 2025Q3: 4,424,968 shares; 2025Q4: 3,711,462 shares; 2026Q1: 2,586,356 shares 2,586,356$42.3M0.42%-1,125,106Timeline
WAYWAYSTAR HLDG CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 1,630,000 shares 1,630,000$39.3M0.39%newTimeline
ARWRARROWHEAD PHARMACEUTICALS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 584,716 shares; 2026Q1: 585,682 shares 585,682$36.7M0.37%+966Timeline
OBIOORCHESTRA BIOMED HLDGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 8,206,159 shares; 2024Q4: 8,206,162 shares; 2025Q1: 8,206,162 shares; 2025Q2: 8,306,062 shares; 2025Q3: 8,306,063 shares; 2025Q4: 8,306,063 shares; 2026Q1: 8,306,063 shares 8,306,063$35.3M0.35%0Timeline
VSTMVERASTEM INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 4,245,476 shares; 2025Q2: 4,251,616 shares; 2025Q3: 5,426,306 shares; 2025Q4: 6,576,306 shares; 2026Q1: 6,576,306 shares 6,576,306$34.9M0.35%0Timeline
EVMNEVOMMUNE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,283,671 shares; 2026Q1: 1,502,235 shares 1,502,235$34.5M0.34%+218,564Timeline
SYKSTRYKER CORPORATIONQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 396,921 shares; 2024Q4: 590,221 shares; 2025Q1: 590,221 shares; 2025Q2: 590,517 shares; 2025Q3: 490,000 shares; 2025Q4: 245,000 shares; 2026Q1: 100,000 shares 100,000$32.9M0.33%-145,000Timeline
SVRASAVARA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 5,952,380 shares; 2026Q1: 5,952,380 shares 5,952,380$32.5M0.32%0Timeline
CADLCANDEL THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 6,422,018 shares 6,422,018$31.5M0.31%newTimeline
AQSTAQUESTIVE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 6,250,000 shares; 2025Q4: 6,250,000 shares; 2026Q1: 7,426,471 shares 7,426,471$30.8M0.31%+1,176,471Timeline
AKTSAKTIS ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 1,592,043 shares 1,592,043$28.5M0.28%newTimeline
NGNENEUROGENE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 1,135,256 shares; 2024Q4: 1,350,256 shares; 2025Q1: 1,348,656 shares; 2025Q2: 1,362,456 shares; 2025Q3: 1,362,456 shares; 2025Q4: 1,362,456 shares; 2026Q1: 1,362,456 shares 1,362,456$27.5M0.27%0Timeline
CGEMCULLINAN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 1,705,960 shares; 2024Q4: 1,705,960 shares; 2025Q1: 1,705,960 shares; 2025Q2: 1,705,960 shares; 2025Q3: 1,705,960 shares; 2025Q4: 1,705,960 shares; 2026Q1: 1,705,960 shares 1,705,960$24.2M0.24%0Timeline
CMPXCOMPASS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 2,500,000 shares; 2025Q4: 2,500,000 shares; 2026Q1: 4,186,599 shares 4,186,599$22.1M0.22%+1,686,599Timeline
DNTHDIANTHUS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 666,667 shares; 2024Q4: 666,667 shares; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 248,063 shares 248,063$20.8M0.21%newTimeline
FLGTFULGENT GENETICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 705,027 shares; 2026Q1: 1,289,000 shares 1,289,000$20.5M0.2%+583,973Timeline
BBNXBETA BIONICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 3,299,870 shares; 2025Q2: 3,299,191 shares; 2025Q3: 3,299,191 shares; 2025Q4: 2,500,000 shares; 2026Q1: 2,000,000 shares 2,000,000$20M0.2%-500,000Timeline
KYMRKYMERA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 240,000 shares; 2026Q1: 240,000 shares 240,000$20M0.2%0Timeline
IPSCCENTURY THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 8,695,652 shares 8,695,652$19.7M0.2%newTimeline
BEAMBEAM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 438,659 shares; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 570,394 shares; 2026Q1: 570,394 shares 570,394$13.6M0.14%0Timeline
AVTXAVALO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 856,962 shares 856,962$12.8M0.13%newTimeline
OCGNOCUGEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 6,666,666 shares 6,666,666$12.1M0.12%newTimeline
HTFLHEARTFLOW INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 495,000 shares; 2025Q4: 495,000 shares; 2026Q1: 495,000 shares 495,000$12M0.12%0Timeline
WVEWAVE LIFE SCIENCES LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 900,000 shares; 2024Q4: 900,000 shares; 2025Q1: 900,000 shares; 2025Q2: 900,000 shares; 2025Q3: 900,000 shares; 2025Q4: 1,350,000 shares; 2026Q1: 1,350,000 shares 1,350,000$9.79M0.1%0Timeline
FRNMPERCEPTIVE CAP SOLUTIONS CORQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 742,500 shares; 2024Q4: 742,500 shares; 2025Q1: 742,500 shares; 2025Q2: 742,500 shares; 2025Q3: 742,500 shares; 2025Q4: 742,500 shares; 2026Q1: 742,500 shares 742,500$8.15M0.08%0Timeline
JBIOJADE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 1,449,273 shares; 2025Q3: 1,449,273 shares; 2025Q4: 1,449,273 shares; 2026Q1: 573,205 shares 573,205$8.05M0.08%-876,068Timeline
CAPRCAPRICOR THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 250,000 shares; 2026Q1: 250,000 shares 250,000$7.6M0.08%0Timeline
MISTMILESTONE PHARMACEUTICALS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 3,256,102 shares; 2024Q4: 2,506,102 shares; 2025Q1: 2,506,102 shares; 2025Q2: 2,506,102 shares; 2025Q3: 2,506,102 shares; 2025Q4: 2,506,102 shares; 2026Q1: 6,331,001 shares 6,331,001$7.53M0.07%+3,824,899Timeline
KLRSKALARIS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,300,000 shares; 2026Q1: 1,300,000 shares 1,300,000$7.5M0.07%0Timeline
IVAINVENTIVA SAQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,298,701 shares; 2026Q1: 1,298,702 shares 1,298,702$7.21M0.07%+1Timeline
ATAIATAIBECKLEY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 2,000,000 shares 2,000,000$7.08M0.07%newTimeline
CBIOCRESCENT BIOPHARMA INC.Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 372,856 shares; 2026Q1: 372,856 shares 372,856$6.85M0.07%0Timeline
LRMRLARIMAR THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 3,125,000 shares; 2025Q4: 3,125,000 shares; 2026Q1: 1,500,000 shares 1,500,000$6.75M0.07%-1,625,000Timeline
TENXTENAX THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 378,346 shares; 2025Q2: 378,346 shares; 2025Q3: 378,346 shares; 2025Q4: 378,346 shares; 2026Q1: 370,246 shares 370,246$5.92M0.06%-8,100Timeline
DFTXDEFINIUM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 300,000 shares 300,000$5.67M0.06%newTimeline
LMRILUMEXA IMAGING HOLDINGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 650,000 shares; 2026Q1: 650,000 shares 650,000$5.59M0.06%0Timeline
FDMT4D MOLECULAR THERAPEUTICS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 475,737 shares; 2026Q1: 475,737 shares 475,737$4.43M0.04%0Timeline
MDLNMEDLINE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 70,000 shares; 2026Q1: 70,000 shares 70,000$3.12M0.03%0Timeline
OMDAOMADA HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 200,000 shares; 2025Q3: 200,000 shares; 2025Q4: 200,000 shares; 2026Q1: 200,000 shares 200,000$2.51M0.03%0Timeline
IRONDISC MEDICINE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 30,000 shares; 2026Q1: 30,000 shares 30,000$1.92M0.02%0Timeline
IMAIMAGENEBIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 334,445 shares; 2025Q4: 334,445 shares; 2026Q1: 334,445 shares 334,445$1.67M0.02%0Timeline
XGNEXAGEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 1,511,866 shares; 2024Q4: 1,511,866 shares; 2025Q1: 1,511,866 shares; 2025Q2: 1,696,866 shares; 2025Q3: 1,696,866 shares; 2025Q4: 790,462 shares; 2026Q1: 395,231 shares 395,231$1.19M0.01%-395,231Timeline
RCKTWROCKET PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 350,000 shares; 2024Q4: 350,000 shares; 2025Q1: 350,000 shares; 2025Q2: 350,000 shares; 2025Q3: 350,000 shares; 2025Q4: 350,000 shares; 2026Q1: 350,000 shares 350,000$7.21K<0.01%0Timeline

Sold out in Q1 2026

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
PENPENUMBRA INC866,499$269Mshares
AXSMAXSOME THERAPEUTICS INC.888,001$162Mshares
PODDINSULET CORP324,600$92.3Mshares
MASIMASIMO CORP683,294$88.9Mshares
RAPTRAPT THERAPEUTICS INC1,637,165$55.5Mshares
TEMTEMPUS AI INC200,000$11.8Mshares
IQVIQVIA HLDGS INC46,000$10.4Mshares
ATAIBECKLEY INCATAIBECKLEY INC2,000,000$8.18Mshares
ALURALLURION TECHNOLOGIES INC COM5,891,430$7.25Mshares
GPCRSTRUCTURE THERAPEUTICS INC100,000$6.96Mshares
MIND MEDICINE MINDMED INCMIND MEDICINE MINDMED INC300,000$4.02Mshares
CRVSCORVUS PHARMACEUTICALS INC447,607$3.45Mshares

How Q1 2026 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001493215-26-000130 base2026-05-15acceptance time not in the bulk data set