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Disclosery

OBIO ORCHESTRA BIOMED HLDGS INC

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COMMON STOCK (common), issuer CIK 1814114

72 managers (77 13F filers) reported a position in OBIO shares at 2026-06-30, 27,693,080 shares in all. 25 filers opened a position and 13 filers sold out during the quarter.

Managers
72
13F filers
77
New
25
Added
22
Reduced
15
Sold out
13
Shares held by filers
27,693,080

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2026

Filers in the available 13F reports with a share position at 2026-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
RTW INVESTMENTS, LP9,556,063$41.2M0.35%+1,250,00013F-HRTimeline
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC5,037,906$21.7M0.34%013F-HRTimelineGroup
VANGUARD GROUP INCgroup of 4 filers holding2,604,090$11.2M+150,609Timeline
BlackRock, Inc.in group BlackRock, Inc.2,510,387$10.8M<0.01%+1,874,67313F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,007,908$4.35M<0.01%+522,41613F-HRTimelineGroup
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.1,000,000$4.32M0.01%013F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding967,927$4.18M+917,617Timeline
Propel Bio Management, LLC896,701$3.87M2.02%013F-HRTimeline
STATE STREET CORPin group STATE STREET CORP516,050$2.23M<0.01%+346,64013F-HRTimelineGroup
RICE HALL JAMES & ASSOCIATES, LLC424,000$1.83M0.09%+404,99913F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co349,544$1.51M<0.01%+84,04513F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP343,640$1.48M<0.01%+225,36613F-HRTimelineGroup
Knott David M Jr253,651$1.09M0.58%013F-HRTimeline
Flat Footed LLC251,372$1.08M0.19%new13F-HRTimeline
Simplify Asset Management Inc.219,387$947K0.01%013F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC179,606$775K<0.01%+24,36413F-HRTimelineGroup
DAFNA Capital Management LLC126,841$547K0.1%013F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC90,000$388K<0.01%+19,10013F-HRTimeline
IFP Advisors, Inc89,608$387K0.01%-9,27913F-HRTimeline
Daytona Street Capital LLC96,398$379K0.28%+43,79813F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp86,103$372K<0.01%new13F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC80,600$348K0.01%+10,00013F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…65,804$284K<0.01%-31,71713F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC56,191$242K<0.01%-22,99413F-HRTimelineGroup
Nuveen, LLCin group TIAA52,118$225K<0.01%new13F-HRTimelineGroup
Holos Integrated Wealth LLC51,595$204K0.1%013F-HRTimeline
NewEdge Advisors, LLC44,083$190K<0.01%013F-HRTimeline
Y-Intercept (Hong Kong) Ltd43,486$188K<0.01%new13F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\39,672$171K<0.01%new13F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd38,814$167K<0.01%new13F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN36,356$157K<0.01%new13F-HRTimelineGroup
HighTower Advisors, LLC35,375$153K<0.01%+17,10013F-HRTimeline
Affinity Asset Advisors, LLC33,400$144K0.01%-369,15013F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/32,689$142K<0.01%new13F-HRTimeline
RHUMBLINE ADVISERS31,940$138K<0.01%new13F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY29,160$126K<0.01%-6,47913F-HRTimelineGroup
ALGERT GLOBAL LLC28,486$123K<0.01%+13,83013F-HRTimeline
Meramec Financial Planners, LLC30,000$115K0.04%013F-HRTimeline
AXQ CAPITAL, LP25,448$110K0.01%new13F-HRTimeline
Invesco Ltd.in group Invesco Ltd.24,689$107K<0.01%new13F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…23,994$104K<0.01%new13F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/23,822$103K<0.01%-28,93913F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO20,880$99.2K<0.01%+16,62213F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP22,563$97.4K<0.01%-37,54413F-HRTimelineGroup
CANADA PENSION PLAN INVESTMENT BOARD21,100$91K<0.01%+9,80013F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding21,030$90.7K+18,085Timeline
NEW YORK STATE COMMON RETIREMENT FUND20,400$88K<0.01%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC20,165$87K<0.01%-5,36413F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC15,360$66.3K<0.01%-40,32013F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC13,518$58.3K<0.01%-45,82413F-HRTimelineGroup
ABLE Financial Group, LLC13,402$57.8K0.01%013F-HRTimeline
Sargent Investment Group, LLC13,120$56.6K0.01%new13F-HRTimeline
Frec Markets, Inc.in group Frec Markets, Inc.13,048$56.3K0.01%013F-HRTimelineGroup
Police & Firemen's Retirement System of…11,755$50.7K<0.01%new13F-HRTimeline
Garden State Investment Advisory Servic…10,562$45.6K0.01%013F-HRTimeline
China Universal Asset Management Co., L…9,530$41.1K<0.01%-49013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS8,214$35.4K<0.01%+6,75813F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc3,924$16.9K<0.01%new13F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…3,617$15.6K<0.01%new13F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…3,601$15.5K<0.01%+3,05413F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…3,187$13.8K<0.01%new13F-HRTimelineGroup
SIMPLEX TRADING, LLC2,564$11.1K<0.01%+18313F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA1,864$8K<0.01%+92813F-HRTimelineGroup
AdvisorNet Financial, Inc1,696$7.32K<0.01%013F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,173$5.06K<0.01%-8713F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP888$3.77K<0.01%+50013F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…549$2.37K<0.01%new13F-HR/ATimeline
FMR LLCin group FMR LLC265$1.14K<0.01%-17,81113F-HRTimelineGroup
Sterling Capital Management LLC140$604<0.01%new13F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.40$173<0.01%new13F-HRTimelineGroup
Caitong International Asset Management …15$65<0.01%new13F-HRTimeline
SBI Securities Co., Ltd.6$26<0.01%013F-HRTimeline