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Disclosery

RARE ULTRAGENYX PHARMACEUTICAL IN

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COM (common), issuer CIK 1515673

282 managers (289 13F filers) reported a position in RARE shares at 2025-12-31, 93,941,826 shares in all. 44 filers opened a position and 65 filers sold out during the quarter.

Managers
282
13F filers
289
New
44
Added
111
Reduced
91
Sold out
65
Shares held by filers
93,941,826

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
VANGUARD GROUP INCin group VANGUARD GROUP INC10,263,815$236M<0.01%+131,08713F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.6,631,554$153M<0.01%+206,29113F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP4,303,046$99M<0.01%+610,55913F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO3,974,030$91.4M0.01%-37,39913F-HRTimelineGroup
SANDS CAPITAL MANAGEMENT, LLC3,485,724$80.2M0.24%-284,12913F-HRTimeline
RTW INVESTMENTS, LP3,000,139$69M0.69%-258,12713F-HRTimeline
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP2,772,692$63.8M0.37%013F-HRTimelineGroup
FMR LLCin group FMR LLC2,666,249$61.3M<0.01%-4,617,04713F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…2,461,910$56.6M0.01%+516,78113F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC2,326,125$53.5M0.04%+1,995,17213F-HRTimelineGroup
MONTANOVA CAPITAL, LLC2,019,000$46.4M1.16%013F-HRTimeline
FRONTIER CAPITAL MANAGEMENT CO LLC1,965,084$45.2M0.48%+895,98613F-HRTimeline
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …1,899,661$43.7M0.05%+354,38213F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,838,208$42.3M<0.01%+257,70113F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY1,826,295$42M<0.01%+916,11213F-HR/ATimelineGroup
JACOBS LEVY EQUITY MANAGEMENT, INC1,749,268$40.2M0.16%-418,46113F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/1,554,366$35.8M<0.01%-755,80813F-HRTimeline
Aberdeen Group plcin group Aberdeen Group plc1,469,951$33.8M0.05%+496,29513F-HRTimelineGroup
GW&K Investment Management, LLC1,375,407$31.6M0.27%+225,23813F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC1,360,497$31.3M0.02%+614,31513F-HRTimelineGroup
Rock Springs Capital Management LP1,267,241$29.1M1.5%+20,90013F-HRTimeline
NORGES BANK1,261,026$29M<0.01%new13F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/1,213,928$27.9M<0.01%+558,90713F-HRTimelineGroup
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…1,231,331$26.6M0.03%-226,85613F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC1,021,499$23.5M0.03%+667,33113F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding905,649$20.8M+61,769Timeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS903,050$20.8M0.01%+330,03113F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC880,644$20.3M0.01%+781,43113F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding872,918$20.1M+118,851Timeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…840,820$19.3M0.02%+36913F-HRTimelineGroup
Nuveen, LLCin group TIAA801,473$18.4M<0.01%+119,32913F-HRTimelineGroup
Candriam S.C.A.799,384$18.4M0.09%+44,67013F-HR/ATimeline
Schonfeld Strategic Advisors LLC741,618$17.1M0.09%-402,97113F-HRTimeline
VOLORIDGE INVESTMENT MANAGEMENT, LLC643,356$14.8M0.05%+160,77413F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\599,473$13.8M<0.01%-946,62813F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co598,924$13.8M<0.01%-1,23613F-HRTimelineGroup
Polar Capital Holdings Plcin group Polar Capital Holdings Plc556,628$12.8M0.06%-27,08213F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP526,686$12.1M<0.01%+27,45413F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management520,054$12M0.02%new13F-HRTimelineGroup
HRT FINANCIAL LP501,679$11.5M0.04%new13F-HRTimeline
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.477,092$11M0.09%new13F-HRTimelineGroup
Palo Alto Investors LP461,294$10.6M1.48%+91,76313F-HRTimeline
FRED ALGER MANAGEMENT, LLCin group FRED ALGER MANAGEMENT, LLC411,863$9.47M0.04%-36,85413F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc411,273$9.46M<0.01%+8,45813F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC400,358$9.21M<0.01%-76,58013F-HR/ATimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC390,599$8.98M0.02%+256,82713F-HRTimelineGroup
Motley Fool Asset Management LLCgroup of 2 filers holding369,934$8.51M-68,206Timeline
RENAISSANCE TECHNOLOGIES LLC366,100$8.42M0.01%+344,20013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC359,148$8.26M<0.01%-66,20313F-HRTimelineGroup
Privium Fund Management B.V.357,502$8.22M1.51%+67,69813F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS348,350$8.01M0.03%+327,50213F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.344,763$7.93M0.01%+107,12313F-HRTimelineGroup
EMERALD ADVISERS, LLCgroup of 2 filers holding332,863$7.66M-328,505Timeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …331,169$7.61M0.01%-13,75413F-HRTimelineGroup
GordonMD Global Investments LPin group GordonMD Global Investments LP329,101$7.57M5.43%13F-HRTimelineGroup
Eversept Partners, LP317,182$7.3M0.41%new13F-HRTimeline
MASSACHUSETTS FINANCIAL SERVICES CO /MA/in group MASSACHUSETTS FINANCIAL SERVI…310,108$7.13M<0.01%-191,05513F-HRTimelineGroup
Franklin Resourcesgroup of 2 filers holding309,062$7.11M-523,874Timeline
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.300,623$6.91M1.44%-51,93513F-HRTimelineGroup
GREAT POINT PARTNERS LLC300,000$6.9M2.24%new13F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp298,706$6.87M<0.01%-26,13913F-HRTimelineGroup
Newtyn Management, LLC295,915$6.81M0.72%new13F-HRTimeline
Verition Fund Management LLC282,376$6.49M0.04%+258,85613F-HRTimeline
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…280,000$6.44M0.01%-150,00013F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC276,927$6.37M<0.01%+138,24313F-HRTimelineGroup
Connor, Clark & Lunn Investment Managem…263,869$6.07M0.02%+184,94713F-HRTimeline
Ensign Peak Advisors, Inc250,571$5.76M0.01%+73,15013F-HR/ATimeline
Invesco Ltd.in group Invesco Ltd.230,271$5.3M<0.01%-564,57813F-HRTimelineGroup
683 Capital Management, LLCin group 683 Capital Management, LLC222,395$5.12M0.43%+116,39513F-HRTimelineGroup
Caption Management, LLC219,500$5.05M0.22%+54,99913F-HRTimeline
ALGERT GLOBAL LLC219,232$5.04M0.08%-102,40113F-HR/ATimeline
Blue Owl Capital Holdings LP212,638$4.89M1.51%-209,80013F-HR/ATimeline
LOS ANGELES CAPITAL MANAGEMENT LLC134,467$4.73M0.02%-60,51513F-HRTimeline
MOORE CAPITAL MANAGEMENT, LP200,000$4.6M0.09%-70,00013F-HRTimeline
Assenagon Asset Management S.A.199,720$4.59M0.01%-52,94913F-HRTimeline
Fisher Asset Management, LLC198,696$4.57M<0.01%+30,61213F-HRTimeline
NOMURA ASSET MANAGEMENT CO LTDgroup of 2 filers holding182,808$4.21M+182,808Timeline
PDT Partners, LLC176,813$4.07M0.26%+20,12013F-HRTimeline
SCHRODER INVESTMENT MANAGEMENT GROUP175,635$4M<0.01%+25,06413F-HRTimeline
Woodline Partners LP171,805$3.95M0.02%-101,44613F-HRTimeline
Swiss National Bank171,052$3.93M<0.01%+6,10013F-HRTimeline
Trexquant Investment LP165,017$3.8M0.03%+9,62913F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA163,227$3.75M<0.01%-73,06213F-HRTimelineGroup
Catalio Capital Management, LP162,550$3.74M0.66%-128,71213F-HR/ATimeline
WCM INVESTMENT MANAGEMENT, LLC163,272$3.72M0.01%-124,83713F-HRTimeline
Rafferty Asset Management, LLC157,061$3.61M0.01%+57713F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO153,726$3.54M<0.01%-36,73613F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…152,316$3.5M<0.01%-81,81013F-HRTimelineGroup
CAPITAL FUND MANAGEMENT S.A.150,201$3.45M0.03%-26,86013F-HRTimeline
Krensavage Asset Management, LLC149,634$3.44M1.22%new13F-HRTimeline
SR One Capital Management, LP137,753$3.17M0.45%new13F-HRTimeline
ExodusPoint Capital Management, LP137,392$3.16M0.04%+30,81713F-HRTimeline
B Group, Inc.135,000$3.1M2.3%013F-HRTimeline
DekaBank Deutsche Girozentrale57,000$2.9M0.01%013F-HRTimeline
Caitong International Asset Management …122,854$2.83M0.69%+122,84313F-HR/ATimeline
XTX Topco Ltdin group XTX Topco Ltd119,996$2.76M0.07%+105,62213F-HRTimelineGroup
COMERICA BANK118,422$2.72M0.01%+34,71113F-HRTimeline
Jump Financial, LLCin group Jump Financial, LLC115,928$2.67M0.03%+58,46013F-HRTimelineGroup
PINNACLE ASSOCIATES LTD111,560$2.57M0.03%-3,28513F-HRTimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…107,903$2.42M0.05%+40,86813F-HRTimelineGroup
RHUMBLINE ADVISERS101,826$2.34M<0.01%-3,90513F-HRTimeline
TWINBEECH CAPITAL LP100,152$2.3M0.16%new13F-HRTimeline
Crestwood Advisors Group, LLC100,131$2.3M0.04%-51313F-HRTimeline
Edgestream Partners, L.P.99,873$2.3M0.06%new13F-HRTimeline
WORLDQUANT MILLENNIUM ADVISORS LLC96,908$2.23M0.01%new13F-HRTimeline
STATE BOARD OF ADMINISTRATION OF FLORID…96,836$2.23M<0.01%+4,07013F-HRTimeline
Aquatic Capital Management LLC87,464$2.01M0.06%-103,99413F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…83,337$1.92M<0.01%+2,44713F-HRTimeline
Sofinnova Investments, Inc.83,300$1.92M0.08%new13F-HRTimeline
TD Asset Management Inc81,964$1.89M<0.01%-15,03413F-HRTimeline
Man Group plcin group Man Group plc78,371$1.8M<0.01%+71,21913F-HRTimelineGroup
Engineers Gate Manager LP76,702$1.76M0.02%+43,57913F-HRTimeline
Affinity Asset Advisors, LLC75,000$1.73M0.12%new13F-HRTimeline
F/m Investments LLC73,484$1.69M0.06%+11,73113F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP72,168$1.66M<0.01%-73,92613F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding70,863$1.63M+4,534Timeline
CITIGROUP INCin group CITIGROUP INC69,511$1.6M<0.01%+43,32213F-HRTimelineGroup
DZ BANK AG Deutsche Zentral Genossensch…in group DZ BANK AG Deutsche Zentral G…67,339$1.55M<0.01%-213,12713F-HRTimelineGroup
Quadrature Capital Ltdin group Quadrature Capital Ltd66,001$1.52M0.02%new13F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN63,563$1.46M<0.01%+38,61513F-HRTimelineGroup
Hennion & Walsh Asset Management, Inc.62,173$1.43M0.05%-11,62113F-HRTimeline
Parkman Healthcare Partners LLC62,030$1.43M0.14%-6,60613F-HRTimeline
Birchview Capital, LP62,000$1.43M0.83%+40,00013F-HRTimeline
FIDEURAM - INTESA SANPAOLO PRIVATE BANK…61,329$1.41M0.05%13F-HR/ATimeline
Entropy Technologies, LP60,641$1.39M0.08%+40,57713F-HRTimeline
STATE OF WISCONSIN INVESTMENT BOARD58,657$1.35M<0.01%-22,28113F-HRTimeline
NORDEA INVESTMENT MANAGEMENT ABin group NORDEA INVESTMENT MANAGEMENT …58,838$1.32M<0.01%-6,89913F-HRTimelineGroup
PROFUND ADVISORS LLC56,624$1.3M0.04%+24,36013F-HRTimeline
FLAX POND CAPITAL, LLC56,238$1.29M0.96%13F-HRTimeline
Ishara Investments LP50,000$1.15M1.34%13F-HRTimeline
Quantinno Capital Management LP49,750$1.14M<0.01%+11,24513F-HRTimeline
Walleye Capital LLCgroup of 2 filers holding49,651$1.14M-26,538Timeline
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC49,137$1.13M0.01%+2,06113F-HRTimelineGroup
Scientech Research LLC48,032$1.1M0.69%+16,72713F-HRTimeline
WEDGE CAPITAL MANAGEMENT L L P/NC42,302$973K0.02%-87713F-HRTimeline
Police & Firemen's Retirement System of…39,398$906K0.01%+5413F-HRTimeline
Treasurer of the State of North Carolina38,620$888K<0.01%-1,76313F-HRTimeline
Alberta Investment Management Corp38,400$883K0.01%new13F-HR/ATimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson36,543$840K<0.01%013F-HRTimelineGroup
Pathstone Holdings, LLCin group Pathstone Holdings, LLC34,339$790K<0.01%+41313F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND34,024$783K<0.01%-1,32213F-HRTimeline
Handelsbanken Fonder AB33,523$771K<0.01%+6,40013F-HRTimeline
SG Americas Securities, LLC32,204$741K<0.01%-93,22513F-HRTimeline
SUPERSTRING CAPITAL MANAGEMENT LP31,738$730K0.39%new13F-HRTimeline
TORONTO DOMINION BANKin group TORONTO DOMINION BANK31,700$729K<0.01%new13F-HRTimelineGroup
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…29,604$681K<0.01%-42,45113F-HRTimelineGroup
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC29,679$663K<0.01%-47,20613F-HR/ATimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…28,240$650K<0.01%+1,87513F-HRTimeline
Headlands Technologies LLC28,207$649K0.05%+2,77813F-HRTimeline
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF O…27,747$638K<0.01%-31213F-HRTimeline
ALLIANCEBERNSTEIN L.P.27,285$628K<0.01%+57713F-HRTimeline
S&CO INC25,255$580K0.04%013F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM23,969$551K<0.01%-1,20713F-HRTimeline
IMC-Chicago, LLC23,397$538K0.01%new13F-HRTimeline
GROUP ONE TRADING LLC23,208$534K0.02%new13F-HRTimeline
Odyssean, LLC22,230$511K0.37%13F-HRTimeline
LMR Partners LLPin group LMR Partners LLP21,674$499K<0.01%new13F-HRTimelineGroup
NATIXIS ADVISORS, LLCin group Natixis Investment Managers21,077$485K<0.01%+1,49813F-HRTimelineGroup
OXFORD ASSET MANAGEMENT LLP20,475$471K0.17%new13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
VIRGINIA RETIREMENT SYSTEMS ET Al20,119$463K<0.01%+6,35013F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC20,112$463K<0.01%-4,92113F-HRTimelineGroup
Knott David M Jr20,006$460K0.21%-31,99413F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC19,934$458K<0.01%-67913F-HRTimelineGroup
VICTORY CAPITAL MANAGEMENT INC19,907$458K<0.01%-278,98413F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC19,851$457K<0.01%-4,70613F-HRTimelineGroup
INCEPTIONR LLC19,714$453K0.13%new13F-HRTimeline
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP18,997$437K<0.01%-6,46113F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…18,862$434K0.12%+7,55113F-HRTimelineGroup
KLP KAPITALFORVALTNING AS18,500$426K<0.01%+80013F-HRTimeline
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP16,642$383K<0.01%-19,69213F-HRTimelineGroup
Fiduciary Trust Coin group Fiduciary Trust Co16,268$374K<0.01%+3,15213F-HRTimelineGroup
DAFNA Capital Management LLC16,000$368K0.09%new13F-HRTimeline
China Universal Asset Management Co., L…15,721$362K0.03%-1,17213F-HRTimeline
Cerity Partners LLCin group Cerity Partners LLC15,678$361K<0.01%new13F-HRTimelineGroup
XPONANCE LLC14,390$331K<0.01%+89613F-HRTimeline
Summit Trail Advisors, LLC14,339$330K0.01%+5,49713F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …14,094$323K<0.01%-77,30013F-HRTimelineGroup
MERCER GLOBAL ADVISORS INC /ADV13,965$321K<0.01%+2,03613F-HRTimeline
Voleon Capital Management LP13,956$321K0.01%new13F-HRTimeline
TUDOR INVESTMENT CORP ET AL13,416$309K<0.01%-45,86213F-HRTimeline
OAK RIDGE INVESTMENTS LLC13,394$308K0.02%-3,23213F-HRTimeline
CWM, LLCin group CWM, LLC13,125$302K<0.01%+9,02813F-HRTimelineGroup
Erste Asset Management GmbHin group Erste Asset Management GmbH15,010$296K<0.01%013F-HRTimelineGroup
B. Metzler seel. Sohn & Co. AGin group B. Metzler seel. Sohn & Co. AG12,862$296K<0.01%-17,17613F-HRTimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC12,671$291K0.04%new13F-HRTimelineGroup
SBI Okasan Asset Management Co.Ltd.14,400$284K0.02%13F-HRTimeline
Blueshift Asset Management, LLC12,343$284K0.08%new13F-HRTimeline
WEALTH ENHANCEMENT ADVISORY SERVICES, L…11,706$264K<0.01%+1,89213F-HRTimeline
CAPTRUST FINANCIAL ADVISORS11,378$262K<0.01%+2,35813F-HRTimeline
Creative Planningin group Creative Planning11,266$259K<0.01%new13F-HRTimelineGroup
Persistent Asset Partners Ltd11,029$254K0.12%+8,94713F-HRTimeline
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co10,623$245K<0.01%-16,30913F-HRTimelineGroup
Mariner, LLCin group Mariner, LLC10,245$236K<0.01%new13F-HRTimelineGroup
Pale Fire Capital SEin group Pale Fire Capital10,211$235K0.03%new13F-HRTimelineGroup
Marex Group Ltdin group Marex Group Ltd9,658$222K<0.01%new13F-HRTimelineGroup
COMMERCE BANKin group COMMERCE BANK9,105$209K<0.01%-9513F-HRTimelineGroup
DARK FOREST CAPITAL MANAGEMENT LP9,071$209K0.01%new13F-HRTimeline
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…8,946$206K<0.01%013F-HRTimeline
Mitsubishi UFJ Asset Management Co., Lt…in group Mitsubishi UFJ Trust & Bankin…7,791$184K<0.01%+99613F-HRTimelineGroup
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…7,716$177K<0.01%+6,63213F-HR/ATimelineGroup