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Disclosery

PRAX PRAXIS PRECISION MEDICINES I

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COM NEW (common), issuer CIK 1689548

149 managers (152 13F filers) reported a position in PRAX shares at 2025-09-30, 24,666,148 shares in all. 27 filers opened a position and 20 filers sold out during the quarter.

Managers
149
13F filers
152
New
27
Added
60
Reduced
45
Sold out
20
Shares held by filers
24,666,148

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
JANUS HENDERSON GROUP PLCin group Janus Henderson2,763,859$146M0.07%+230,45413F-HRTimelineGroup
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…2,374,085$126M0.2%+399,50013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.1,801,080$95.5M<0.01%+210,95213F-HRTimelineGroup
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC1,564,554$82.9M2.4%+811,63313F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.1,495,986$79.3M0.17%+541,91113F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC1,267,286$67.2M<0.01%+51,64213F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/1,003,490$53.2M0.01%-469,58513F-HRTimeline
Cormorant Asset Management, LP1,000,000$53M3.66%-625,00013F-HRTimeline
STATE STREET CORPin group STATE STREET CORP907,108$48.1M<0.01%+209,01513F-HRTimelineGroup
Soleus Capital Management, L.P.859,166$45.5M2.43%-107,57413F-HRTimeline
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…840,851$44.6M0.68%+153,92013F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP689,488$36.5M0.26%013F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY643,495$34.1M<0.01%-582,84413F-HR/ATimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC593,021$31.4M<0.01%+367,02913F-HRTimelineGroup
Driehaus Capital Management LLC500,551$26.5M0.19%-30,43713F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/482,861$25.6M<0.01%+29,45813F-HR/ATimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC457,032$24.2M<0.01%+5,30113F-HRTimelineGroup
Woodline Partners LP417,669$22.1M0.1%+371,71713F-HRTimeline
Assenagon Asset Management S.A.409,779$21.7M0.03%-194,51913F-HRTimeline
CIBC Asset Management Inc388,759$20.6M0.06%013F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources314,157$16.7M<0.01%+713F-HRTimelineGroup
Vivo Capital, LLC198,895$10.5M0.85%+31,29513F-HRTimeline
Sofinnova Investments, Inc.172,833$9.16M0.56%+157,11613F-HRTimeline
5AM Venture Management, LLC170,000$9.01M3.3%013F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP168,353$8.92M<0.01%-45,35913F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co161,661$8.57M<0.01%+9,21713F-HRTimelineGroup
ALGERT GLOBAL LLC160,818$8.52M0.14%+133,24813F-HR/ATimeline
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.141,516$7.5M0.02%+16,51613F-HRTimelineGroup
Velan Capital Investment Management LP132,805$7.04M6.61%-16,52913F-HRTimeline
Logos Global Management LP125,000$6.62M0.65%-100,00013F-HRTimeline
UBS Group AGgroup of 2 filers holding120,568$6.39M-62,911Timeline
READYSTATE ASSET MANAGEMENT LP109,177$5.79M0.28%new13F-HRTimeline
Exome Asset Management LLC101,996$5.41M3.57%+42,99413F-HRTimeline
HighVista Strategies LLC95,002$5.04M1.23%+27,71413F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC76,637$4.06M<0.01%-12,08713F-HR/ATimelineGroup
KENNEDY CAPITAL MANAGEMENT LLC76,218$4.04M0.09%+5,77313F-HRTimeline
Tri Locum Partners LP75,986$4.03M0.93%-119,44613F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP68,141$3.61M<0.01%new13F-HRTimelineGroup
72 Investment Holdings, LLC65,933$3.49M5.14%013F-HRTimeline
Candriam S.C.A.62,866$3.33M0.02%-80513F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…61,241$3.25M<0.01%+5,36013F-HRTimelineGroup
PFM Health Sciences, LP60,578$3.21M0.27%-24,13513F-HRTimeline
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.57,901$3.07M0.73%-51,85613F-HRTimelineGroup
Qube Research & Technologies Ltd57,304$3.04M<0.01%new13F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp56,288$2.98M<0.01%+3,73513F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding52,588$2.79M-89Timeline
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…51,210$2.71M0.39%+41,21013F-HRTimelineGroup
ACUTA CAPITAL PARTNERS, LLC49,751$2.64M2.72%-24,33613F-HRTimeline
FMR LLCin group FMR LLC43,211$2.29M<0.01%+5,11113F-HRTimelineGroup
TD Asset Management Inc40,884$2.17M<0.01%-23,05413F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC39,660$2.1M0.05%-78,46113F-HRTimeline
Nuveen, LLCin group TIAA38,549$2.04M<0.01%013F-HRTimelineGroup
Rafferty Asset Management, LLC37,573$1.99M0.01%+12,76813F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP37,414$1.98M<0.01%new13F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …35,829$1.9M<0.01%-20,30213F-HRTimelineGroup
Swiss National Bank35,500$1.88M<0.01%+4,70013F-HRTimeline
SummitTX Capital, L.P.34,928$1.85M0.08%new13F-HRTimeline
Y-Intercept (Hong Kong) Ltd32,186$1.71M0.04%new13F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC31,687$1.68M<0.01%+18,68413F-HRTimelineGroup
B Group, Inc.31,500$1.67M1.6%-3,50013F-HRTimeline
CONGRESS ASSET MANAGEMENT CO30,439$1.61M0.01%new13F-HRTimeline
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP28,966$1.54M<0.01%new13F-HRTimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC28,571$1.51M0.31%-248,37913F-HRTimelineGroup
PRELUDE CAPITAL MANAGEMENT, LLC28,102$1.49M0.12%+8,20213F-HRTimeline
Knott David M Jr28,000$1.48M0.62%new13F-HRTimeline
RHUMBLINE ADVISERS26,794$1.42M<0.01%-54713F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO26,208$1.39M<0.01%+12,27013F-HR/ATimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding23,650$1.25M-1,010Timeline
SIMPLEX TRADING, LLC22,529$1.19M0.03%-2,79913F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC21,904$1.16M<0.01%+7,32413F-HRTimelineGroup
DARK FOREST CAPITAL MANAGEMENT LP21,684$1.15M0.04%new13F-HR/ATimeline
Invesco Ltd.in group Invesco Ltd.20,868$1.11M<0.01%+4,92913F-HRTimelineGroup
Quarry LP20,001$1.06M0.26%+15,20113F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.19,796$1.05M<0.01%+74013F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…18,583$985K<0.01%+2,23713F-HRTimeline
ALLIANCEBERNSTEIN L.P.18,060$957K<0.01%+2013F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc16,824$892K<0.01%+15413F-HRTimelineGroup
GROUP ONE TRADING LLC16,628$881K0.03%new13F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC15,268$809K<0.01%new13F-HRTimelineGroup
PCG Wealth Advisors, LLC14,483$768K0.22%new13F-HRTimeline
JACOBS LEVY EQUITY MANAGEMENT, INC13,898$737K<0.01%-31,18413F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\13,856$734K<0.01%+1,73213F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN13,605$721K<0.01%+2,35313F-HRTimelineGroup
SG Americas Securities, LLC13,496$715K<0.01%new13F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC11,172$595K<0.01%new13F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…10,520$558K<0.01%013F-HRTimelineGroup
HUSSMAN STRATEGIC ADVISORS, INC.10,500$556K0.12%013F-HRTimeline
ALPS ADVISORS INCin group ALPS ADVISORS INC10,424$552K<0.01%-57013F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD9,033$479K<0.01%-5,72613F-HRTimeline
Trexquant Investment LP8,905$472K<0.01%new13F-HRTimeline
Freestone Grove Partners LP8,269$438K<0.01%new13F-HRTimeline
PROFUND ADVISORS LLC8,079$428K0.01%+2,81813F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC7,798$413K<0.01%-2,56813F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC7,754$411K<0.01%-96513F-HRTimeline
NISA INVESTMENT ADVISORS, LLC7,129$378K<0.01%+6,50013F-HRTimeline
Phoenix Financial Ltd.in group Phoenix Financial Ltd.6,817$362K<0.01%new13F-HR/ATimelineGroup
Creative Planningin group Creative Planning6,660$353K<0.01%+16513F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND6,600$350K<0.01%013F-HRTimeline
STATE BOARD OF ADMINISTRATION OF FLORID…6,425$341K<0.01%013F-HRTimeline
Caption Management, LLC6,357$337K0.02%-32,67913F-HRTimeline
GSA CAPITAL PARTNERS LLP5,740$304K0.03%-6,26813F-HRTimeline
Lion Point Capital, LP5,700$302K1.72%new13F-HRTimeline
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP5,508$292K<0.01%-1,00113F-HRTimelineGroup
Cerity Partners LLCin group Cerity Partners LLC5,450$289K<0.01%-16113F-HRTimelineGroup
ARIZONA STATE RETIREMENT SYSTEM5,417$287K<0.01%new13F-HRTimeline
Police & Firemen's Retirement System of…4,915$260K<0.01%+1,12613F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS4,469$237K<0.01%new13F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…4,404$233K<0.01%+4,15513F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS4,385$232K<0.01%+2,33813F-HRTimelineGroup
KLP KAPITALFORVALTNING AS4,000$212K<0.01%+1,20013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA3,956$209K<0.01%-18,63713F-HRTimelineGroup
VIRGINIA RETIREMENT SYSTEMS ET Al3,900$207K<0.01%new13F-HRTimeline
Coastal Bridge Advisors, LLC3,846$204K0.02%new13F-HRTimeline
ProShare Advisors LLC3,826$203K<0.01%new13F-HRTimeline
China Universal Asset Management Co., L…3,689$196K0.02%-40213F-HRTimeline
CITIGROUP INCin group CITIGROUP INC2,807$149K<0.01%-9,05913F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…2,527$134K0.04%+43913F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…2,127$113K<0.01%+29013F-HRTimelineGroup
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.2,000$106K<0.01%-3,00013F-HRTimelineGroup
AlphaQuest LLC1,999$106K0.01%+1,88313F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…1,519$80.5K<0.01%-17013F-HRTimelineGroup
Sterling Capital Management LLC1,146$60.7K<0.01%+70113F-HRTimeline
CWM, LLCin group CWM, LLC757$40K<0.01%+413F-HRTimelineGroup
AMALGAMATED BANK599$32K<0.01%013F-HRTimeline
GF FUND MANAGEMENT CO. LTD.453$24K<0.01%-2413F-HRTimeline
Farther Finance Advisors, LLC230$12.2K<0.01%013F-HRTimeline
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…217$12K<0.01%013F-HRTimeline
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …163$9K<0.01%+3013F-HRTimelineGroup
SUMMIT SECURITIES GROUP LLC164$8.69K<0.01%new13F-HRTimeline
Arax Advisory Partners152$8.06K<0.01%+12913F-HRTimeline
GAMMA Investing LLC150$7.95K<0.01%-513F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.140$7.42K<0.01%new13F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\112$5.94K<0.01%-5413F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…98$5.19K<0.01%-6913F-HRTimeline
SBI Securities Co., Ltd.83$4.4K<0.01%+813F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.80$4.16K<0.01%+2613F-HRTimelineGroup
Larson Financial Group LLC71$3.76K<0.01%+3313F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.62$3K<0.01%013F-HRTimelineGroup
ROTHSCHILD INVESTMENT LLC45$2.38K<0.01%-513F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…24$1.27K<0.01%013F-HRTimelineGroup
FSA Wealth Management LLC21$1.11K<0.01%013F-HRTimeline
Hemington Wealth Management30$1K<0.01%013F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…18$954<0.01%013F-HRTimelineGroup
Allworth Financial LP12$636<0.01%-5713F-HRTimeline
Parkside Financial Bank & Trust10$530<0.01%013F-HRTimeline
IFP Advisors, Inc3$159<0.01%+313F-HR/ATimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…2$106<0.01%new13F-HRTimelineGroup
Essential Partners LLC1$53<0.01%013F-HRTimeline
Covestor Ltd2$00%013F-HRTimelineValue filed as zero, left out of ratios.