FMR LLC in group FMR LLC More: the full row for FMR LLC 13,834,514 $638M 0.03% +1,324,581 13F-HR Timeline Group JANUS HENDERSON GROUP PLC in group Janus Henderson More: the full row for JANUS HENDERSON GROUP PLC 13,387,188 $618M 0.28% +282,985 13F-HR Timeline Group VANGUARD GROUP INC group of 2 filers holding More: the full row for VANGUARD GROUP INC 12,219,210 $564M -117,098 Timeline T. Rowe Price Investment Management, In… More: the full row for T. Rowe Price Investment Management, Inc. 11,296,333 $521M 0.33% +2,981,038 13F-HR/A Timeline RA CAPITAL MANAGEMENT, L.P. in group RA CAPITAL MANAGEMENT, L.P. More: the full row for RA CAPITAL MANAGEMENT, L.P. 10,724,599 $495M 5.07% -1,241,392 13F-HR Timeline Group BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 10,246,378 $473M 0.01% +290,400 13F-HR Timeline Group WELLINGTON MANAGEMENT GROUP LLP in group WELLINGTON MANAGEMENT GROUP L… More: the full row for WELLINGTON MANAGEMENT GROUP LLP 5,966,310 $275M 0.05% +933,539 13F-HR Timeline Group STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 4,980,005 $230M 0.01% +194,116 13F-HR Timeline Group Paradigm Biocapital Advisors LP in group Paradigm Biocapital Advisors … More: the full row for Paradigm Biocapital Advisors LP 4,068,020 $188M 5.03% +283,265 13F-HR Timeline Group Deep Track Capital, LP More: the full row for Deep Track Capital, LP 4,000,000 $185M 4.21% +1,000,000 13F-HR Timeline D. E. Shaw & Co., Inc. in group D. E. Shaw & Co., Inc. More: the full row for D. E. Shaw & Co., Inc. 3,631,053 $168M 0.13% -659,737 13F-HR Timeline Group WESTFIELD CAPITAL MANAGEMENT CO LP More: the full row for WESTFIELD CAPITAL MANAGEMENT CO LP 3,539,717 $163M 0.68% -192,998 13F-HR Timeline Kynam Capital Management, LP More: the full row for Kynam Capital Management, LP 2,922,335 $135M 8.78% -149,253 13F-HR Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 2,866,305 $132M 0.01% -17,735 13F-HR Timeline Group ADAGE CAPITAL PARTNERS GP, L.L.C. in group ADAGE CAPITAL PARTNERS GP, L.… More: the full row for ADAGE CAPITAL PARTNERS GP, L.L.C. 1,725,000 $79.6M 0.12% +1,392,000 13F-HR Timeline Group Caligan Partners LP More: the full row for Caligan Partners LP 1,704,815 $78.7M 7.2% new 13F-HR Timeline Polar Capital Holdings Plc in group Polar Capital Holdings Plc More: the full row for Polar Capital Holdings Plc 1,672,783 $77.2M 0.35% +1,257,253 13F-HR Timeline Group UBS Group AG group of 2 filers holding More: the full row for UBS Group AG 1,482,603 $68.4M +236,886 Timeline Pivotal bioVenture Partners Investment … in group Pivotal bioVenture Partners I… More: the full row for Pivotal bioVenture Partners Investment Advisor LLC 1,372,425 $63.3M 24.48% 0 13F-HR Timeline Group MAVERICK CAPITAL LTD More: the full row for MAVERICK CAPITAL LTD 1,354,237 $62.5M 0.67% +64,670 13F-HR Timeline CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 1,293,830 $59.7M 0.01% +423 13F-HR Timeline Group NORGES BANK More: the full row for NORGES BANK 1,228,939 $56.7M 0.01% new 13F-HR Timeline Eversept Partners, LP More: the full row for Eversept Partners, LP 1,197,722 $55.3M 3.1% -224,261 13F-HR Timeline PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 1,175,339 $54.2M 0.01% -513,144 13F-HR Timeline JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 1,085,519 $50.1M <0.01% -479,517 13F-HR Timeline Group GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 1,078,120 $49.7M 0.01% +102,743 13F-HR/A Timeline Group NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 1,034,180 $47.7M 0.01% -39,166 13F-HR Timeline Group Aberdeen Group plc in group Aberdeen Group plc More: the full row for Aberdeen Group plc 979,765 $45.2M 0.07% +256,972 13F-HR Timeline Group EVENTIDE ASSET MANAGEMENT, LLC More: the full row for EVENTIDE ASSET MANAGEMENT, LLC 917,115 $42.3M 0.66% +537,785 13F-HR Timeline NOVO HOLDINGS A/S More: the full row for NOVO HOLDINGS A/S 916,160 $42.3M 3.28% 0 13F-HR Timeline Pictet Asset Management Holding SA in group Pictet Asset Management Holdi… More: the full row for Pictet Asset Management Holding SA 881,435 $40.7M 0.04% -148,194 13F-HR Timeline Group Capital Research Global Investors in group Capital Research Global Inves… More: the full row for Capital Research Global Investors 842,978 $38.9M 0.01% 0 13F-HR Timeline Group MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 835,387 $38.5M <0.01% +50,904 13F-HR/A Timeline Group Saturn V Capital Management LP More: the full row for Saturn V Capital Management LP 798,940 $36.9M 6.77% +10,499 13F-HR Timeline Trails Edge Capital Partners, LP More: the full row for Trails Edge Capital Partners, LP 737,470 $34M 8.41% 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 701,634 $32.4M <0.01% +66,564 13F-HR Timeline Group JENNISON ASSOCIATES LLC More: the full row for JENNISON ASSOCIATES LLC 677,553 $31.3M 0.02% -493,346 13F-HR Timeline Logos Global Management LP More: the full row for Logos Global Management LP 650,000 $30M 2% +25,000 13F-HR Timeline Soleus Capital Management, L.P. More: the full row for Soleus Capital Management, L.P. 608,958 $28.1M 1.19% new 13F-HR Timeline BROWN ADVISORY INC in group BROWN ADVISORY INC More: the full row for BROWN ADVISORY INC 566,925 $26.2M 0.04% -110,060 13F-HR Timeline Group VICTORY CAPITAL MANAGEMENT INC More: the full row for VICTORY CAPITAL MANAGEMENT INC 549,514 $25.4M 0.01% +234,622 13F-HR Timeline Assenagon Asset Management S.A. More: the full row for Assenagon Asset Management S.A. 544,728 $25.1M 0.04% +324,778 13F-HR Timeline Ensign Peak Advisors, Inc More: the full row for Ensign Peak Advisors, Inc 527,688 $24.3M 0.04% -1,165 13F-HR/A Timeline FEDERATED HERMES, INC. in group FEDERATED HERMES, INC. More: the full row for FEDERATED HERMES, INC. 523,489 $24.2M 0.04% +505,333 13F-HR Timeline Group BOOTHBAY FUND MANAGEMENT, LLC More: the full row for BOOTHBAY FUND MANAGEMENT, LLC 497,740 $23M 0.59% +369,009 13F-HR Timeline EcoR1 Capital, LLC More: the full row for EcoR1 Capital, LLC 450,000 $20.8M 0.95% new 13F-HR Timeline Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 449,363 $20.7M <0.01% +9,751 13F-HR Timeline Group MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 424,294 $19.6M 0.01% -524,673 13F-HR Timeline Group Spruce Street Capital LP More: the full row for Spruce Street Capital LP 400,360 $18.5M 6.1% 13F-HR Timeline Ikarian Capital, LLC in group Ikarian Capital, LLC More: the full row for Ikarian Capital, LLC 378,682 $17.5M 2.26% +67,000 13F-HR Timeline Group TD Asset Management Inc More: the full row for TD Asset Management Inc 363,734 $16.8M 0.01% -34,746 13F-HR Timeline AMERICAN CENTURY COMPANIES INC in group AMERICAN CENTURY COMPANIES INC More: the full row for AMERICAN CENTURY COMPANIES INC 357,300 $16.5M 0.01% +13,273 13F-HR Timeline Group DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 342,894 $15.8M 0.01% -54,895 13F-HR Timeline Group FRANKLIN RESOURCES INC in group Franklin Resources More: the full row for FRANKLIN RESOURCES INC 336,143 $15.5M <0.01% +37 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 326,574 $15.1M 0.01% +120,775 13F-HR Timeline Group ADAR1 Capital Management, LLC in group ADAR1 Capital Management, LLC More: the full row for ADAR1 Capital Management, LLC 315,642 $14.6M 1.09% +102,578 13F-HR/A Timeline Group Nuveen, LLC in group TIAA More: the full row for Nuveen, LLC 307,202 $14.2M <0.01% -177,436 13F-HR Timeline Group AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 305,194 $14.1M <0.01% -69,708 13F-HR Timeline Group Artisan Partners Limited Partnership More: the full row for Artisan Partners Limited Partnership 304,049 $14M 0.02% new 13F-HR Timeline BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 296,195 $13.7M 0.01% -97,719 13F-HR Timeline Group Elmind Capital, LP More: the full row for Elmind Capital, LP 291,500 $13.4M 3.97% 13F-HR Timeline JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 279,604 $12.9M 0.02% -64,093 13F-HR Timeline Group TANG CAPITAL MANAGEMENT LLC in group TANG CAPITAL MANAGEMENT LLC More: the full row for TANG CAPITAL MANAGEMENT LLC 275,000 $12.7M 0.63% -25,000 13F-HR Timeline Group Woodline Partners LP More: the full row for Woodline Partners LP 274,740 $12.7M 0.05% +27,754 13F-HR Timeline University of Wisconsin Foundation More: the full row for University of Wisconsin Foundation 247,000 $11.4M 9.58% new 13F-HR Timeline Alyeska Investment Group, L.P. in group Alyeska Investment Group, L.P. More: the full row for Alyeska Investment Group, L.P. 244,775 $11.3M 0.03% 0 13F-HR Timeline Group CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 241,880 $11.2M 0.01% -71,198 13F-HR Timeline Group Swiss National Bank More: the full row for Swiss National Bank 230,400 $10.6M 0.01% +5,300 13F-HR Timeline Qube Research & Technologies Ltd More: the full row for Qube Research & Technologies Ltd 207,090 $9.56M 0.01% -346,759 13F-HR Timeline C WorldWide Group Holding A/S in group C WorldWide Group Holding A/S More: the full row for C WorldWide Group Holding A/S 195,000 $9M 0.16% 0 13F-HR Timeline Group SEGALL BRYANT & HAMILL, LLC More: the full row for SEGALL BRYANT & HAMILL, LLC 193,423 $8.92M 0.12% +8,628 13F-HR Timeline DIMENSIONAL FUND ADVISORS LP in group DIMENSIONAL FUND ADVISORS LP More: the full row for DIMENSIONAL FUND ADVISORS LP 191,786 $8.85M <0.01% +163,419 13F-HR Timeline Group RAYMOND JAMES FINANCIAL INC in group RAYMOND JAMES FINANCIAL INC More: the full row for RAYMOND JAMES FINANCIAL INC 185,851 $8.45M <0.01% -3,442 13F-HR Timeline Group Point72 Asset Management, L.P. in group Point72 Asset Management, L.P. More: the full row for Point72 Asset Management, L.P. 161,614 $7.46M 0.01% -535,229 13F-HR Timeline Group RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 150,919 $6.96M 0.01% -32,293 13F-HR Timeline SILVERARC CAPITAL MANAGEMENT, LLC in group SILVERARC CAPITAL MANAGEMENT,… More: the full row for SILVERARC CAPITAL MANAGEMENT, LLC 148,787 $6.87M 0.99% -165,552 13F-HR Timeline Group California Public Employees Retirement … More: the full row for California Public Employees Retirement System 144,603 $6.67M <0.01% -11 13F-HR Timeline NAN FUNG TRINITY (HK) LTD More: the full row for NAN FUNG TRINITY (HK) LTD 142,930 $6.59M 0.52% +38,680 13F-HR Timeline Invesco Ltd. in group Invesco Ltd. More: the full row for Invesco Ltd. 141,220 $6.52M <0.01% -37,861 13F-HR Timeline Group WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 134,075 $6.19M <0.01% +8,027 13F-HR Timeline Group ALLIANCEBERNSTEIN L.P. More: the full row for ALLIANCEBERNSTEIN L.P. 133,882 $6.18M <0.01% -1,344 13F-HR Timeline Rafferty Asset Management, LLC More: the full row for Rafferty Asset Management, LLC 133,764 $6.17M 0.02% -15,650 13F-HR Timeline READYSTATE ASSET MANAGEMENT LP More: the full row for READYSTATE ASSET MANAGEMENT LP 131,637 $6.07M 0.27% new 13F-HR Timeline Cormorant Asset Management, LP More: the full row for Cormorant Asset Management, LP 125,000 $5.77M 0.33% -50,000 13F-HR Timeline Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 120,301 $5.55M <0.01% -10,100 13F-HR Timeline Group NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 116,817 $5.39M 0.01% -4,970 13F-HR Timeline HighVista Strategies LLC More: the full row for HighVista Strategies LLC 114,049 $5.26M 1.36% +27,247 13F-HR Timeline HRT FINANCIAL LP More: the full row for HRT FINANCIAL LP 113,950 $5.26M 0.02% -84 13F-HR Timeline TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 111,310 $5.14M 0.01% +3,723 13F-HR Timeline Group CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 110,862 $5.12M 0.01% +1,418 13F-HR Timeline MANUFACTURERS LIFE INSURANCE COMPANY, T… in group MANUFACTURERS LIFE INSURANCE … More: the full row for MANUFACTURERS LIFE INSURANCE COMPANY, THE 108,445 $4.97M <0.01% -28,425 13F-HR Timeline Group Creative Planning in group Creative Planning More: the full row for Creative Planning 102,686 $4.74M <0.01% +22,363 13F-HR Timeline Group NEXTBio Capital Management LP More: the full row for NEXTBio Capital Management LP 95,485 $4.41M 2.58% 13F-HR Timeline Jump Financial, LLC in group Jump Financial, LLC More: the full row for Jump Financial, LLC 89,822 $4.14M 0.05% -101,878 13F-HR Timeline Group Mirae Asset Global Investments Co., Ltd. group of 2 filers holding More: the full row for Mirae Asset Global Investments Co., Ltd. 85,594 $3.94M +1,582 Timeline TWINBEECH CAPITAL LP More: the full row for TWINBEECH CAPITAL LP 78,239 $3.61M 0.26% -149,848 13F-HR Timeline BANQUE PICTET & CIE SA More: the full row for BANQUE PICTET & CIE SA 71,815 $3.31M 0.03% -3,049 13F-HR Timeline Universal- Beteiligungs- und Serviceges… in group Universal- Beteiligungs- und … More: the full row for Universal- Beteiligungs- und Servicegesellschaft mbH 70,124 $3.24M 0.01% +35,974 13F-HR Timeline Group Man Group plc in group Man Group plc More: the full row for Man Group plc 68,913 $3.18M 0.01% -175,984 13F-HR Timeline Group STATE OF WISCONSIN INVESTMENT BOARD More: the full row for STATE OF WISCONSIN INVESTMENT BOARD 68,285 $3.15M 0.01% -8,301 13F-HR Timeline ALGERT GLOBAL LLC More: the full row for ALGERT GLOBAL LLC 67,439 $3.11M 0.05% -104,710 13F-HR/A Timeline RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 65,211 $3.01M <0.01% -15,266 13F-HR Timeline LAZARD ASSET MANAGEMENT LLC in group LAZARD ASSET MANAGEMENT LLC More: the full row for LAZARD ASSET MANAGEMENT LLC 64,978 $3M 0.01% -54,114 13F-HR Timeline Group MetLife Investment Management, LLC in group MetLife Investment Management… More: the full row for MetLife Investment Management, LLC 63,807 $2.94M 0.01% -2,759 13F-HR Timeline Group INTECH INVESTMENT MANAGEMENT LLC More: the full row for INTECH INVESTMENT MANAGEMENT LLC 58,234 $2.69M 0.02% -9,722 13F-HR Timeline FRED ALGER MANAGEMENT, LLC in group FRED ALGER MANAGEMENT, LLC More: the full row for FRED ALGER MANAGEMENT, LLC 57,808 $2.67M 0.01% +12,394 13F-HR Timeline Group ENVESTNET ASSET MANAGEMENT INC in group ENVESTNET ASSET MANAGEMENT INC More: the full row for ENVESTNET ASSET MANAGEMENT INC 50,798 $2.34M <0.01% -19,013 13F-HR Timeline Group BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 50,762 $2.34M <0.01% -206,905 13F-HR Timeline Group PROFUND ADVISORS LLC More: the full row for PROFUND ADVISORS LLC 50,447 $2.33M 0.07% +17,525 13F-HR Timeline Ishara Investments LP More: the full row for Ishara Investments LP 50,000 $2.31M 2.68% 13F-HR Timeline VOYA INVESTMENT MANAGEMENT LLC in group VOYA INVESTMENT MANAGEMENT LLC More: the full row for VOYA INVESTMENT MANAGEMENT LLC 47,755 $2.2M <0.01% +13,964 13F-HR Timeline Group Rock Springs Capital Management LP More: the full row for Rock Springs Capital Management LP 47,000 $2.17M 0.11% +35,900 13F-HR Timeline Handelsbanken Fonder AB More: the full row for Handelsbanken Fonder AB 40,900 $1.89M 0.01% -4,100 13F-HR Timeline Zurcher Kantonalbank (Zurich Cantonalba… More: the full row for Zurcher Kantonalbank (Zurich Cantonalbank) 40,002 $1.85M <0.01% +1,253 13F-HR Timeline ArrowMark Colorado Holdings LLC More: the full row for ArrowMark Colorado Holdings LLC 40,000 $1.85M 0.04% 0 13F-HR Timeline State of New Jersey Common Pension Fund… in group State of New Jersey Common Pe… More: the full row for State of New Jersey Common Pension Fund D 39,880 $1.84M 0.01% -26,778 13F-HR Timeline Group BROWN BROTHERS HARRIMAN & CO in group BROWN BROTHERS HARRIMAN & CO More: the full row for BROWN BROTHERS HARRIMAN & CO 38,033 $1.75M 0.01% 0 13F-HR Timeline Group GUGGENHEIM CAPITAL LLC in group GUGGENHEIM CAPITAL LLC More: the full row for GUGGENHEIM CAPITAL LLC 34,501 $1.59M 0.01% -934 13F-HR Timeline Group Brevan Howard Capital Management LP in group Brevan Howard Capital Managem… More: the full row for Brevan Howard Capital Management LP 34,351 $1.58M 0.03% -32,782 13F-HR Timeline Group SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 34,116 $1.57M <0.01% -84,618 13F-HR Timeline Group ARIZONA STATE RETIREMENT SYSTEM More: the full row for ARIZONA STATE RETIREMENT SYSTEM 32,800 $1.51M 0.01% -1,533 13F-HR Timeline DekaBank Deutsche Girozentrale More: the full row for DekaBank Deutsche Girozentrale 20,000 $1.49M <0.01% 0 13F-HR Timeline Voleon Capital Management LP More: the full row for Voleon Capital Management LP 31,779 $1.47M 0.03% -47,148 13F-HR Timeline Headlands Technologies LLC More: the full row for Headlands Technologies LLC 31,706 $1.46M 0.12% -1,025 13F-HR Timeline HARBOR CAPITAL ADVISORS, INC. More: the full row for HARBOR CAPITAL ADVISORS, INC. 31,274 $1.44M 0.11% +252 13F-HR Timeline Police & Firemen's Retirement System of… More: the full row for Police & Firemen's Retirement System of New Jersey 31,122 $1.44M 0.01% -908 13F-HR Timeline SEI INVESTMENTS CO in group SEI INVESTMENTS CO More: the full row for SEI INVESTMENTS CO 30,940 $1.43M <0.01% -59,008 13F-HR Timeline Group Alberta Investment Management Corp More: the full row for Alberta Investment Management Corp 30,100 $1.39M 0.01% new 13F-HR/A Timeline Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 26,865 $1.24M <0.01% -251,268 13F-HR Timeline Group STATE BOARD OF ADMINISTRATION OF FLORID… More: the full row for STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 26,738 $1.23M <0.01% 0 13F-HR Timeline ProShare Advisors LLC More: the full row for ProShare Advisors LLC 26,725 $1.23M <0.01% +2,524 13F-HR Timeline TEACHERS RETIREMENT SYSTEM OF THE STATE… More: the full row for TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY 25,760 $1.19M 0.01% 0 13F-HR Timeline Seven Fleet Capital Management LP More: the full row for Seven Fleet Capital Management LP 25,365 $1.17M 0.79% 13F-HR/A Timeline KLP KAPITALFORVALTNING AS More: the full row for KLP KAPITALFORVALTNING AS 25,000 $1.15M <0.01% +400 13F-HR Timeline Aquatic Capital Management LLC More: the full row for Aquatic Capital Management LLC 24,485 $1.13M 0.03% -101,300 13F-HR Timeline Pathstone Holdings, LLC in group Pathstone Holdings, LLC More: the full row for Pathstone Holdings, LLC 24,229 $1.12M <0.01% +2,140 13F-HR Timeline Group MARTINGALE ASSET MANAGEMENT L P More: the full row for MARTINGALE ASSET MANAGEMENT L P 23,992 $1.11M 0.03% +401 13F-HR Timeline Progeny 3, Inc. More: the full row for Progeny 3, Inc. 23,300 $1.08M 0.06% new 13F-HR Timeline DIADEMA PARTNERS LP More: the full row for DIADEMA PARTNERS LP 22,972 $1.06M 0.63% -195,313 13F-HR Timeline LOS ANGELES CAPITAL MANAGEMENT LLC More: the full row for LOS ANGELES CAPITAL MANAGEMENT LLC 22,007 $985K <0.01% -4,896 13F-HR Timeline China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 21,331 $984K 0.08% -1,425 13F-HR Timeline LPL Financial LLC More: the full row for LPL Financial LLC 20,489 $945K <0.01% +1,172 13F-HR Timeline SG Americas Securities, LLC More: the full row for SG Americas Securities, LLC 20,429 $943K <0.01% -5,129 13F-HR Timeline NOMURA ASSET MANAGEMENT CO LTD group of 2 filers holding More: the full row for NOMURA ASSET MANAGEMENT CO LTD 20,000 $923K +20,000 Timeline TEACHER RETIREMENT SYSTEM OF TEXAS More: the full row for TEACHER RETIREMENT SYSTEM OF TEXAS 17,291 $798K <0.01% -11,187 13F-HR Timeline DNB Asset Management AS in group DNB Asset Management AS More: the full row for DNB Asset Management AS 16,471 $760K <0.01% +5,235 13F-HR Timeline Group Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 16,455 $759K <0.01% -517 13F-HR Timeline Group PRUDENTIAL FINANCIAL INC in group PRUDENTIAL FINANCIAL INC More: the full row for PRUDENTIAL FINANCIAL INC 16,425 $758K <0.01% -3,041 13F-HR Timeline Group Odyssean, LLC More: the full row for Odyssean, LLC 16,182 $747K 0.54% 13F-HR Timeline GILDER GAGNON HOWE & CO LLC More: the full row for GILDER GAGNON HOWE & CO LLC 16,109 $743K 0.01% -32 13F-HR Timeline Verition Fund Management LLC More: the full row for Verition Fund Management LLC 15,731 $726K <0.01% -26,127 13F-HR Timeline CIBC Bancorp USA Inc. group of 2 filers holding More: the full row for CIBC Bancorp USA Inc. 15,331 $707K +13,975 Timeline XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 15,261 $704K 0.02% new 13F-HR Timeline Group PNC Financial Services Group, Inc. in group PNC Financial Services Group,… More: the full row for PNC Financial Services Group, Inc. 14,917 $688K <0.01% +514 13F-HR Timeline Group SummitTX Capital, L.P. More: the full row for SummitTX Capital, L.P. 14,869 $686K 0.02% +8,210 13F-HR Timeline Walleye Capital LLC in group Walleye Capital LLC More: the full row for Walleye Capital LLC 14,805 $683K <0.01% new 13F-HR Timeline Group AQR CAPITAL MANAGEMENT LLC in group AQR CAPITAL MANAGEMENT LLC More: the full row for AQR CAPITAL MANAGEMENT LLC 14,762 $681K <0.01% new 13F-HR Timeline Group Quantinno Capital Management LP More: the full row for Quantinno Capital Management LP 14,501 $669K <0.01% +2,138 13F-HR Timeline PUBLIC EMPLOYEES RETIREMENT ASSOCIATION… More: the full row for PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO 14,024 $647K <0.01% 0 13F-HR Timeline Baird Financial Group, Inc. in group Baird Financial Group, Inc. More: the full row for Baird Financial Group, Inc. 13,788 $636K <0.01% -929 13F-HR Timeline Group CANADA LIFE ASSURANCE Co in group CANADA LIFE ASSURANCE Co More: the full row for CANADA LIFE ASSURANCE Co 13,403 $619K <0.01% +2,039 13F-HR Timeline Group Baker Avenue Asset Management, LP More: the full row for Baker Avenue Asset Management, LP 13,143 $606K 0.01% 0 13F-HR Timeline Thrivent Financial for Lutherans in group Thrivent Financial for Luther… More: the full row for Thrivent Financial for Lutherans 11,742 $541K <0.01% +4,558 13F-HR Timeline Group AlphaQuest LLC More: the full row for AlphaQuest LLC 10,513 $485K 0.03% -433 13F-HR Timeline CANADA PENSION PLAN INVESTMENT BOARD More: the full row for CANADA PENSION PLAN INVESTMENT BOARD 10,400 $480K <0.01% new 13F-HR Timeline STRS OHIO More: the full row for STRS OHIO 10,300 $475K <0.01% -1,700 13F-HR Timeline Daiwa Securities Group Inc. in group Daiwa Securities Group Inc. More: the full row for Daiwa Securities Group Inc. 10,083 $465K <0.01% +369 13F-HR Timeline Group Avior Wealth Management, LLC More: the full row for Avior Wealth Management, LLC 9,487 $438K 0.01% -1,544 13F-HR Timeline Virtus Investment Advisers, LLC group of 2 filers holding More: the full row for Virtus Investment Advisers, LLC 9,479 $437K +6,177 Timeline Ameritas Investment Partners, Inc. in group Ameritas Investment Partners,… More: the full row for Ameritas Investment Partners, Inc. 9,294 $429K 0.01% -271 13F-HR Timeline Group ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 9,224 $426K <0.01% -939,825 13F-HR Timeline Group XPONANCE LLC More: the full row for XPONANCE LLC 9,080 $419K <0.01% +69 13F-HR Timeline Perbak Capital Partners LLP More: the full row for Perbak Capital Partners LLP 8,899 $411K 0.13% -32,032 13F-HR Timeline Vident Advisory, LLC in group Vident Advisory, LLC More: the full row for Vident Advisory, LLC 8,821 $407K <0.01% +1,007 13F-HR Timeline Group Mariner, LLC in group Mariner, LLC More: the full row for Mariner, LLC 8,539 $394K <0.01% +784 13F-HR Timeline Group Sumitomo Mitsui Trust Group, Inc. in group Sumitomo Mitsui Trust Group, … More: the full row for Sumitomo Mitsui Trust Group, Inc. 8,284 $382K <0.01% -62 13F-HR Timeline Group Quantitative Investment Management, LLC More: the full row for Quantitative Investment Management, LLC 8,222 $379K 0.04% new 13F-HR Timeline Meeder Advisory Services, Inc. in group Meeder Advisory Services, Inc. More: the full row for Meeder Advisory Services, Inc. 8,104 $374K 0.02% +2,286 13F-HR Timeline Group HSBC HOLDINGS PLC in group HSBC HOLDINGS PLC More: the full row for HSBC HOLDINGS PLC 7,798 $363K <0.01% -42,827 13F-HR/A Timeline Group Cetera Investment Advisers More: the full row for Cetera Investment Advisers 7,797 $360K <0.01% -701 13F-HR Timeline Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 7,158 $330K 0.01% +1,166 13F-HR Timeline Group Allianz Asset Management GmbH in group Allianz SE More: the full row for Allianz Asset Management GmbH 7,100 $328K <0.01% new 13F-HR Timeline Group J.Safra Asset Management Corp More: the full row for J.Safra Asset Management Corp 7,054 $325K 0.02% +1,070 13F-HR Timeline MACKENZIE FINANCIAL CORP More: the full row for MACKENZIE FINANCIAL CORP 7,174 $325K <0.01% -829 13F-HR Timeline Qsemble Capital Management, LP More: the full row for Qsemble Capital Management, LP 6,701 $309K 0.03% +355 13F-HR Timeline Sterling Capital Management LLC More: the full row for Sterling Capital Management LLC 6,614 $305K <0.01% -1,314 13F-HR Timeline ACADIAN ASSET MANAGEMENT LLC in group ACADIAN ASSET MANAGEMENT LLC More: the full row for ACADIAN ASSET MANAGEMENT LLC 6,295 $289K <0.01% -78,085 13F-HR Timeline Group SIGNATUREFD, LLC More: the full row for SIGNATUREFD, LLC 6,167 $285K <0.01% +1,028 13F-HR Timeline Allspring Global Investments Holdings, … in group Allspring Global Investments … More: the full row for Allspring Global Investments Holdings, LLC 5,850 $272K <0.01% new 13F-HR Timeline Group Leonteq Securities AG More: the full row for Leonteq Securities AG 5,486 $253K 0.01% -1,275 13F-HR Timeline Quantbot Technologies LP More: the full row for Quantbot Technologies LP 5,399 $249K 0.01% new 13F-HR Timeline Swiss Life Asset Management Ltd in group Swiss Life Asset Management L… More: the full row for Swiss Life Asset Management Ltd 5,399 $249K <0.01% new 13F-HR Timeline Group Persistent Asset Partners Ltd More: the full row for Persistent Asset Partners Ltd 5,334 $246K 0.12% -44,742 13F-HR Timeline Amundi in group Amundi More: the full row for Amundi 5,090 $235K <0.01% new 13F-HR Timeline Group TWO SIGMA SECURITIES, LLC More: the full row for TWO SIGMA SECURITIES, LLC 5,025 $232K 0.03% new 13F-HR Timeline FARALLON CAPITAL MANAGEMENT, L.L.C. More: the full row for FARALLON CAPITAL MANAGEMENT, L.L.C. 5,000 $231K <0.01% new 13F-HR Timeline The filing omitted confidential holdings, a later amendment may add them. Quarry LP More: the full row for Quarry LP 5,000 $231K 0.04% new 13F-HR Timeline PRINCIPAL FINANCIAL GROUP INC group of 2 filers holding More: the full row for PRINCIPAL FINANCIAL GROUP INC 4,932 $228K -3,217 Timeline Neo Ivy Capital Management More: the full row for Neo Ivy Capital Management 4,803 $222K 0.04% -78,307 13F-HR Timeline Values First Advisors, Inc. More: the full row for Values First Advisors, Inc. 4,680 $216K 0.11% new 13F-HR Timeline