13F-HR filed by EcoR1 Capital, LLC
EcoR1 Capital, LLC filed this 13F-HR for the quarter ended 2025-12-31, filed 2026-02-17, with 30 holding rows worth $2,204,008,593.
- Accession
- 0000935836-26-000101
- Filer
- CIK 1587114
- Filed
- 2026-02-17
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2025
A holdings report, 30 entries on the cover page, a total value of $2,204,008,593 stated on the cover page (in dollars after the unit check, H1), rows summing to $2,204,008,593 with VALUE read as dollars as filed, 13F file number 028-16764. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| ZYMEWORKS INC | 98985Y108 | COM | 22,970,388 | $604,810,316 | dollars as filed | |
| ANAPTYSBIO INC | 032724106 | COM | 7,880,094 | $382,026,957 | dollars as filed | |
| JAZZ PHARMACEUTICALS PLC SHS USD | G50871105 | Stock | 1,706,469 | $290,099,730 | dollars as filed | |
| CRINETICS PHARMACEUTICALS INC COM | 22663K107 | Stock | 4,288,120 | $199,611,986 | dollars as filed | |
| CENTESSA PHARMACEUTICALS PLC | 152309100 | SPONSORED ADS | 3,115,000 | $77,906,150 | dollars as filed | |
| CRISPR THERAPEUTICS AG NAMEN AKT | H17182108 | Stock | 1,389,276 | $72,853,633 | dollars as filed | |
| MBX BIOSCIENCES INC COM | 55287L101 | Stock | 2,123,604 | $66,978,470 | dollars as filed | |
| IMMUNOME INC | 45257U108 | COM | 2,855,590 | $61,338,073 | dollars as filed | |
| ORIC PHARMACEUTICALS INC | 68622P109 | COM | 6,728,116 | $55,035,989 | dollars as filed | |
| LAKEFRONT BIOTHERAPEUTICS NV | 36315X101 | SPON ADR | 1,667,119 | $54,514,791 | dollars as filed | |
| XENCOR INC | 98401F105 | COMMON STOCK | 3,251,112 | $49,774,525 | dollars as filed | |
| BRIDGEBIO ONCOLOGY THERAPEUT | 107924102 | COM NEW | 2,823,126 | $35,345,538 | dollars as filed | |
| ETON PHARMACEUTICALS INC | 29772L108 | COMMON STOCK | 2,030,544 | $34,336,499 | dollars as filed | |
| CG ONCOLOGY INC | 156944100 | COMMON STOCK | 772,000 | $32,053,440 | dollars as filed | |
| ZENAS BIOPHARMA INC COM | 98937L105 | Stock | 789,500 | $28,666,745 | dollars as filed | |
| NEUROGENE INC | 64135M105 | COMMON STOCK | 1,271,342 | $26,189,645 | dollars as filed | |
| STRUCTURE THERAPEUTICS INC COMP | 86366E106 | EQUITY | 334,380 | $23,256,129 | dollars as filed | |
| VAXCYTE INC COM | 92243G108 | Stock | 450,000 | $20,763,000 | dollars as filed | |
| AQUESTIVE THERAPEUTICS INC COM | 03843E104 | Stock | 2,625,000 | $16,957,500 | dollars as filed | |
| VOYAGER THERAPEUTICS INC | 92915B106 | COMMON STOCK | 4,002,847 | $15,731,189 | dollars as filed | |
| CG ONCOLOGY INC | 156944100 | COMMON STOCK | 292,800 | $12,157,056 | dollars as filed | call |
| ATARA BIOTHERAPEUTICS INC | 046513206 | COM NEW | 573,183 | $10,368,880 | dollars as filed | |
| MANNKIND CORP COM NEW | 56400P706 | Stock | 1,660,000 | $9,412,200 | dollars as filed | |
| NUVATION BIO INC | 67080N119 | WARR | 963,333 | $8,631,464 | dollars as filed | |
| EVOLUS INC | 30052C107 | COM | 675,000 | $4,488,750 | dollars as filed | |
| IBIO INC | 451033708 | CMN | 2,228,000 | $4,300,040 | dollars as filed | |
| MEREO BIOPHARMA GROUP PLC | 589492107 | CMN | 7,856,466 | $3,273,789 | dollars as filed | |
| CAMP4 THERAPEUTICS CORP | 13463J101 | COM | 325,000 | $1,992,250 | dollars as filed | |
| XENCOR INC | 98401F105 | COMMON STOCK | 67,500 | $1,033,425 | dollars as filed | call |
| SURROZEN INC | 86889P117 | *W EXP 08/01/203 | 4,444 | $100,434 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0000935836-26-000101 | this filing | 2026-02-17 | acceptance time not in the bulk data set |