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Disclosery

LXEO LEXEO THERAPEUTICS INC

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COMMON STOCK (common), issuer CIK 1907108

142 managers (146 13F filers) reported a position in LXEO shares at 2025-12-31, 76,461,222 shares in all. 44 filers opened a position and 9 filers sold out during the quarter.

Managers
142
13F filers
146
New
44
Added
61
Reduced
26
Sold out
9
Shares held by filers
76,461,222

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
JANUS HENDERSON GROUP PLCin group Janus Henderson5,509,635$54.7M0.02%-595,89213F-HRTimelineGroup
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.5,000,000$49.6M0.51%new13F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.4,907,563$48.7M<0.01%+2,736,47113F-HRTimelineGroup
Paradigm Biocapital Advisors LPin group Paradigm Biocapital Advisors …4,763,198$47.3M1.27%new13F-HRTimelineGroup
Vestal Point Capital, LP4,475,000$44.4M1.63%+1,225,00013F-HRTimeline
Frazier Life Sciences Management, L.P.4,424,725$43.9M1.18%013F-HRTimeline
VANGUARD GROUP INCgroup of 2 filers holding3,910,746$38.8M+1,667,861Timeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC3,774,317$37.5M0.03%+55,27413F-HRTimelineGroup
Avoro Capital Advisors LLC3,300,000$32.8M0.32%new13F-HR/ATimeline
Affinity Asset Advisors, LLC3,200,000$31.8M2.28%-670,52713F-HRTimeline
Woodline Partners LP3,197,760$31.8M0.12%+625,59813F-HRTimeline
STATE STREET CORPin group STATE STREET CORP3,187,722$31.7M<0.01%+2,642,87713F-HRTimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC2,125,000$21.1M0.43%new13F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.1,894,722$18.8M0.03%-47,12713F-HRTimelineGroup
Octagon Capital Advisors LP1,725,000$17.1M2.14%new13F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management1,635,026$16.2M0.03%-2,278,76213F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,445,887$14.4M<0.01%+724,00613F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC1,393,161$13.8M1.03%-138,79213F-HR/ATimelineGroup
MONTANOVA CAPITAL, LLC1,250,000$12.4M0.31%new13F-HRTimeline
683 Capital Management, LLCin group 683 Capital Management, LLC1,120,000$11.1M0.92%+197,33813F-HRTimelineGroup
Nantahala Capital Management, LLCin group Nantahala Capital Management,…1,000,000$9.93M0.59%new13F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC908,024$9.02M0.01%-1,405,61813F-HRTimelineGroup
Blackstone Inc.in group Blackstone Inc.904,959$8.99M0.03%-219,96313F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP862,892$8.57M<0.01%-49,64113F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC781,855$7.76M<0.01%+639,45313F-HR/ATimelineGroup
Siren, L.L.C.in group Siren, L.L.C.720,622$7.16M0.21%+117,18713F-HRTimelineGroup
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…617,608$6.13M0.89%-161,00313F-HRTimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC513,011$5.09M0.66%-54,59013F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding481,867$4.78M+397,104Timeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.480,205$4.77M<0.01%+467,38713F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.463,029$4.6M<0.01%new13F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP457,052$4.54M<0.01%+220,59913F-HRTimelineGroup
Verition Fund Management LLC428,458$4.25M0.02%+13,59513F-HRTimeline
DAFNA Capital Management LLC340,859$3.38M0.79%-17,22413F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC337,386$3.35M<0.01%-10,53713F-HRTimelineGroup
UBS Group AGin group UBS Group AG281,083$2.79M<0.01%+31,17413F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS257,417$2.56M<0.01%+226,69013F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC243,294$2.42M<0.01%+76,75613F-HRTimelineGroup
Y-Intercept (Hong Kong) Ltd231,163$2.3M0.05%new13F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC217,772$2.16M<0.01%+68,47213F-HRTimeline
Nuveen, LLCin group TIAA211,529$2.1M<0.01%+178,42713F-HRTimelineGroup
Privium Fund Management B.V.192,550$1.91M0.35%+19413F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co192,210$1.91M<0.01%+86,45013F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC188,754$1.87M<0.01%+77,17513F-HRTimelineGroup
Spruce Street Capital LP175,000$1.74M0.57%13F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp166,749$1.66M<0.01%+95,07213F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/160,288$1.59M<0.01%+132,00913F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY140,181$1.39M<0.01%+42,12413F-HR/ATimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC140,096$1.39M<0.01%+10,62413F-HRTimelineGroup
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC139,835$1.39M0.03%013F-HRTimelineGroup
BOOTHBAY FUND MANAGEMENT, LLC136,377$1.35M0.03%-44,36713F-HRTimeline
Qube Research & Technologies Ltd133,257$1.32M<0.01%new13F-HRTimeline
Burkehill Global Management, LP125,000$1.24M0.08%new13F-HRTimeline
Rafferty Asset Management, LLC102,159$1.01M<0.01%new13F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC92,608$920K<0.01%new13F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…83,230$826K<0.01%new13F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN70,736$702K<0.01%+51,47413F-HRTimelineGroup
RHUMBLINE ADVISERS69,369$689K<0.01%+37,60513F-HRTimeline
Atom Investors LP68,491$680K0.05%new13F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding63,214$628K+11,374Timeline
ALLIANCEBERNSTEIN L.P.61,810$614K<0.01%+32,44013F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\57,166$568K<0.01%+32,84413F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC50,909$505K<0.01%new13F-HRTimelineGroup
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC45,988$457K<0.01%+9,83413F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding38,804$384K+25,263Timeline
PROFUND ADVISORS LLC38,054$378K0.01%new13F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…35,721$355K<0.01%new13F-HRTimelineGroup
PANAGORA ASSET MANAGEMENT INC34,297$341K<0.01%013F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/33,872$337K<0.01%+21,90713F-HRTimeline
Graham Capital Management, L.P.32,898$327K0.01%new13F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO29,861$297K<0.01%+15,50213F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…27,230$270K0.07%new13F-HRTimelineGroup
WINTON GROUP Ltdin group WINTON GROUP Ltd26,900$267K0.01%new13F-HRTimelineGroup
Mitsubishi UFJ Asset Management Co., Lt…in group Mitsubishi UFJ Trust & Bankin…26,209$252K<0.01%new13F-HRTimelineGroup
IEQ CAPITAL, LLC24,692$245K<0.01%-8,88913F-HRTimeline
Cerity Partners LLCin group Cerity Partners LLC22,439$223K<0.01%-1,15113F-HRTimelineGroup
Pale Fire Capital SEin group Pale Fire Capital22,302$221K0.03%-11,34813F-HRTimelineGroup
OMERS ADMINISTRATION Corp20,900$208K<0.01%new13F-HRTimeline
Soltis Investment Advisors LLC20,000$199K0.01%013F-HR/ATimeline
NEW YORK STATE COMMON RETIREMENT FUND19,887$197K<0.01%+15,70013F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …19,147$190K<0.01%new13F-HRTimelineGroup
CWM, LLCin group CWM, LLC18,953$188K<0.01%+8913F-HRTimelineGroup
SG Americas Securities, LLC18,640$185K<0.01%new13F-HRTimeline
Police & Firemen's Retirement System of…16,373$163K<0.01%+10,33313F-HRTimeline
Persistent Asset Partners Ltd16,025$159K0.08%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC15,293$152K<0.01%+7,86113F-HRTimelineGroup
ProShare Advisors LLC14,752$146K<0.01%new13F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC14,188$141K<0.01%+2,31713F-HRTimeline
CAXTON CORP13,943$138K3.24%-3,38913F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
WEALTH ENHANCEMENT ADVISORY SERVICES, L…14,330$136K<0.01%+8613F-HRTimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC13,400$133K<0.01%-35,00013F-HRTimeline
FMR LLCin group FMR LLC13,388$133K<0.01%-4513F-HRTimelineGroup
SIMPLEX TRADING, LLC13,031$129K<0.01%+12,53213F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC12,538$125K<0.01%new13F-HRTimelineGroup
China Universal Asset Management Co., L…11,893$118K0.01%+2,42713F-HRTimeline
AlphaQuest LLC11,726$116K0.01%new13F-HRTimeline
GSA CAPITAL PARTNERS LLP11,463$114K0.01%new13F-HRTimeline
Ethic Inc.11,449$114K<0.01%+13013F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC11,234$112K<0.01%+34413F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd11,144$111K<0.01%-15,57113F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC10,976$109K<0.01%new13F-HRTimelineGroup
LOS ANGELES CAPITAL MANAGEMENT LLC11,555$109K<0.01%+48013F-HRTimeline
Creative Planningin group Creative Planning10,358$103K<0.01%new13F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA6,721$67K<0.01%-12813F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…5,872$58.3K<0.01%+3,61513F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc5,631$55.9K<0.01%+3,59913F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…5,121$50.9K<0.01%+2,73413F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…3,884$38.6K<0.01%+2,14813F-HRTimeline
Caitong International Asset Management …3,714$36.9K0.01%new13F-HR/ATimeline
Sterling Capital Management LLC3,636$36.1K<0.01%+1,90313F-HRTimeline
Allworth Financial LP3,386$33.6K<0.01%+3,07913F-HRTimeline
NISA INVESTMENT ADVISORS, LLC2,765$27.5K<0.01%013F-HRTimeline
BESSEMER GROUP INCin group BESSEMER GROUP INC2,380$24K<0.01%new13F-HRTimelineGroup
AMALGAMATED BANK1,982$20K<0.01%+1,35913F-HRTimeline
GROUP ONE TRADING LLC1,816$18K<0.01%new13F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,434$14.2K<0.01%+27213F-HRTimeline
Aquatic Capital Management LLC1,085$10.8K<0.01%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…826$8.2K<0.01%-2,91113F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…731$7.26K<0.01%013F-HRTimelineGroup
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…700$6.95K<0.01%+50013F-HR/ATimelineGroup
US BANCORP \DE\in group US BANCORP \DE\555$5.51K<0.01%new13F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…487$4.84K<0.01%-18613F-HRTimelineGroup
Essential Partners LLC476$4.73K<0.01%+513F-HRTimeline
Torren Management, LLC321$3.19K<0.01%13F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.312$3.1K<0.01%013F-HRTimelineGroup
SIGNATUREFD, LLC290$2.88K<0.01%+11213F-HRTimeline
Larson Financial Group LLC240$2.38K<0.01%+23513F-HRTimeline
True Wealth Design, LLC226$2.25K<0.01%013F-HRTimeline
SBI Securities Co., Ltd.217$2.15K<0.01%+2013F-HRTimeline
IFP Advisors, Inc203$2.02K<0.01%013F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.243$2K<0.01%new13F-HRTimelineGroup
Fortitude Family Office, LLC124$1.23K<0.01%013F-HRTimeline
Basecamp Wealth Advisors LLC113$1.12K<0.01%13F-HRTimeline
Steward Partners Investment Advisory, L…100$993<0.01%013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.57$566<0.01%-11313F-HRTimelineGroup
Farther Finance Advisors, LLC57$566<0.01%new13F-HRTimeline
Rialto Wealth Management, LLC53$527<0.01%new13F-HRTimeline
GAMMA Investing LLC50$497<0.01%new13F-HRTimeline
Sunbelt Securities, Inc.16$159<0.01%013F-HRTimeline
Clearstead Advisors, LLC4$40<0.01%-30013F-HRTimeline
Smartleaf Asset Management LLC4$39<0.01%new13F-HRTimeline
ROTHSCHILD INVESTMENT LLC1$10<0.01%new13F-HRTimeline