Frazier Life Sciences Management, L.P. More: the full row for Frazier Life Sciences Management, L.P. 24,675,188 $399M 10.27% +1,945,752 13F-HR Timeline T. Rowe Price Investment Management, In… More: the full row for T. Rowe Price Investment Management, Inc. 21,259,646 $344M 0.24% +5,148,232 13F-HR Timeline BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 20,151,406 $326M 0.01% +4,554,076 13F-HR Timeline Group Venrock Adviser, LLC More: the full row for Venrock Adviser, LLC 16,382,812 $265M 9.89% -1,474,271 13F-HR Timeline RTW INVESTMENTS, LP More: the full row for RTW INVESTMENTS, LP 16,157,175 $261M 2.6% +16,010,524 13F-HR Timeline VANGUARD GROUP INC group of 7 filers holding More: the full row for VANGUARD GROUP INC 14,878,011 $241M +14,843,352 Timeline VANGUARD CAPITAL MANAGEMENT LLC : 11,249,738 (<0.01%) 13F-HR/A VANGUARD PORTFOLIO MANAGEMENT LLC : 1,773,757 (<0.01%) 13F-HR VANGUARD FIDUCIARY TRUST CO : 1,537,915 (0.01%) 13F-HR Vanguard Global Advisers, LLC : 113,645 (<0.01%) 13F-HR VANGUARD ASSET MANAGEMENT, Ltd : 111,757 (<0.01%) 13F-HR Vanguard Personalized Indexing Ma… : 46,898 (0.01%) 13F-HR Vanguard Investments Australia, L… : 44,301 (<0.01%) 13F-HR Vivo Capital, LLC More: the full row for Vivo Capital, LLC 12,151,480 $197M 16.34% +2,878,052 13F-HR/A Timeline Siren, L.L.C. in group Siren, L.L.C. More: the full row for Siren, L.L.C. 11,244,246 $182M 5.04% +2,486,997 13F-HR Timeline Group Logos Global Management LP More: the full row for Logos Global Management LP 11,150,000 $180M 9.29% -1,850,000 13F-HR Timeline Paradigm Biocapital Advisors LP in group Paradigm Biocapital Advisors … More: the full row for Paradigm Biocapital Advisors LP 10,392,702 $168M 3.44% -3,766,393 13F-HR Timeline Group STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 9,300,084 $150M 0.01% +3,125,442 13F-HR Timeline Group ARCH Venture Management, LLC More: the full row for ARCH Venture Management, LLC 7,091,557 $115M 16.95% -3,963,997 13F-HR Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 5,996,149 $97M 0.01% +1,069,814 13F-HR Timeline Group Cormorant Asset Management, LP More: the full row for Cormorant Asset Management, LP 5,800,000 $93.8M 4.73% new 13F-HR Timeline Affinity Asset Advisors, LLC More: the full row for Affinity Asset Advisors, LLC 5,350,000 $86.6M 5.08% +1,450,000 13F-HR Timeline Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 5,143,985 $83.2M 0.16% +5,045,912 13F-HR Timeline Group GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 4,875,186 $78.9M 0.01% +1,543,768 13F-HR Timeline Group JANUS HENDERSON GROUP PLC in group Janus Henderson More: the full row for JANUS HENDERSON GROUP PLC 3,710,966 $60M 0.03% new 13F-HR/A Timeline Group 5AM Venture Management, LLC More: the full row for 5AM Venture Management, LLC 3,485,971 $56.4M 15.66% -1,919,433 13F-HR Timeline MONTANOVA CAPITAL, LLC More: the full row for MONTANOVA CAPITAL, LLC 3,434,967 $55.6M 1.51% -11,067,037 13F-HR Timeline Commodore Capital LP in group Commodore Capital LP More: the full row for Commodore Capital LP 3,175,000 $51.4M 2.97% new 13F-HR Timeline Group BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 3,055,897 $49.4M <0.01% +1,444,047 13F-HR Timeline Group a16z Capital Management, L.L.C. in group a16z Capital Management, L.L.… More: the full row for a16z Capital Management, L.L.C. 2,862,500 $46.3M 3.59% 0 13F-HR Timeline Group Woodline Partners LP More: the full row for Woodline Partners LP 2,831,538 $45.8M 0.17% +900,896 13F-HR/A Timeline UBS Group AG group of 2 filers holding More: the full row for UBS Group AG 2,107,587 $34.1M +1,937,056 Timeline ADAGE CAPITAL PARTNERS GP, L.L.C. in group ADAGE CAPITAL PARTNERS GP, L.… More: the full row for ADAGE CAPITAL PARTNERS GP, L.L.C. 2,100,000 $34M 0.05% new 13F-HR Timeline Group CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 1,898,224 $30.7M <0.01% +224,820 13F-HR Timeline Group SILVERARC CAPITAL MANAGEMENT, LLC in group SILVERARC CAPITAL MANAGEMENT,… More: the full row for SILVERARC CAPITAL MANAGEMENT, LLC 1,851,812 $30M 3.53% +534,228 13F-HR Timeline Group PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 1,815,340 $29.4M <0.01% +1,711,837 13F-HR Timeline DIMENSIONAL FUND ADVISORS LP in group DIMENSIONAL FUND ADVISORS LP More: the full row for DIMENSIONAL FUND ADVISORS LP 1,786,389 $28.9M 0.01% +10,704 13F-HR Timeline Group NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 1,701,623 $27.5M <0.01% +370,115 13F-HR Timeline Group VICTORY CAPITAL MANAGEMENT INC More: the full row for VICTORY CAPITAL MANAGEMENT INC 1,654,497 $26.8M 0.02% +1,636,106 13F-HR Timeline FMR LLC in group FMR LLC More: the full row for FMR LLC 1,490,080 $24.1M <0.01% +968,625 13F-HR Timeline Group RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 1,398,869 $22.6M 0.04% +548,769 13F-HR Timeline D. E. Shaw & Co., Inc. in group D. E. Shaw & Co., Inc. More: the full row for D. E. Shaw & Co., Inc. 1,219,534 $19.7M 0.02% +1,017,596 13F-HR Timeline Group Rock Springs Capital Management LP More: the full row for Rock Springs Capital Management LP 1,103,469 $17.9M 1.05% +151,759 13F-HR Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 1,087,301 $17.6M 0.01% +1,054,815 13F-HR Timeline Group MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 989,210 $16M <0.01% +178,825 13F-HR Timeline Group EcoR1 Capital, LLC More: the full row for EcoR1 Capital, LLC 900,000 $14.6M 0.62% new 13F-HR Timeline First Turn Management, LLC More: the full row for First Turn Management, LLC 867,639 $14M 1.57% new 13F-HR Timeline JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 924,405 $13.8M <0.01% -228,685 13F-HR/A Timeline Group Holocene Advisors, LP More: the full row for Holocene Advisors, LP 760,722 $12.3M 0.03% new 13F-HR Timeline Invesco Ltd. in group Invesco Ltd. More: the full row for Invesco Ltd. 759,932 $12.3M <0.01% +430,137 13F-HR Timeline Group Integral Health Asset Management, LLC More: the full row for Integral Health Asset Management, LLC 700,000 $11.3M 0.6% new 13F-HR Timeline Point72 Asset Management, L.P. in group Point72 Asset Management, L.P. More: the full row for Point72 Asset Management, L.P. 693,309 $11.2M 0.02% new 13F-HR Timeline Group AQR CAPITAL MANAGEMENT LLC in group AQR CAPITAL MANAGEMENT LLC More: the full row for AQR CAPITAL MANAGEMENT LLC 691,205 $11.2M 0.01% +21,329 13F-HR Timeline Group AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 670,597 $10.9M <0.01% new 13F-HR/A Timeline Group ALLIANCEBERNSTEIN L.P. More: the full row for ALLIANCEBERNSTEIN L.P. 2,644,920 $9.84M <0.01% +2,436,110 13F-HR Timeline WELLINGTON MANAGEMENT GROUP LLP in group WELLINGTON MANAGEMENT GROUP L… More: the full row for WELLINGTON MANAGEMENT GROUP LLP 595,379 $9.63M <0.01% +52,183 13F-HR Timeline Group MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 575,996 $9.32M 0.01% -1,661,955 13F-HR Timeline Group ExodusPoint Capital Management, LP More: the full row for ExodusPoint Capital Management, LP 575,715 $9.32M 0.09% -915,252 13F-HR Timeline Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 559,629 $9.05M <0.01% +12,853 13F-HR Timeline Group Nuveen, LLC in group TIAA More: the full row for Nuveen, LLC 543,021 $8.79M <0.01% +118,308 13F-HR Timeline Group Ensign Peak Advisors, Inc More: the full row for Ensign Peak Advisors, Inc 500,723 $8.1M 0.02% new 13F-HR/A Timeline CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 498,381 $8.06M 0.01% -531,964 13F-HR Timeline Group JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 455,019 $7.36M 0.01% -457,500 13F-HR Timeline Group MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 426,526 $6.9M 0.01% +364,566 13F-HR Timeline Group Spruce Street Capital LP More: the full row for Spruce Street Capital LP 422,543 $6.84M 1.64% -3,467,089 13F-HR Timeline Creative Planning in group Creative Planning More: the full row for Creative Planning 418,834 $6.78M <0.01% +37,139 13F-HR Timeline Group PRUDENTIAL FINANCIAL INC in group PRUDENTIAL FINANCIAL INC More: the full row for PRUDENTIAL FINANCIAL INC 416,715 $6.74M 0.01% +403,960 13F-HR Timeline Group Parkman Healthcare Partners LLC More: the full row for Parkman Healthcare Partners LLC 406,702 $6.58M 0.68% new 13F-HR Timeline TD Asset Management Inc More: the full row for TD Asset Management Inc 394,260 $6.38M 0.01% +164,420 13F-HR Timeline AMERICAN CENTURY COMPANIES INC in group AMERICAN CENTURY COMPANIES INC More: the full row for AMERICAN CENTURY COMPANIES INC 380,977 $6.16M <0.01% +215,618 13F-HR Timeline Group Polymer Capital Management (HK) LTD More: the full row for Polymer Capital Management (HK) LTD 357,670 $5.79M 0.81% new 13F-HR Timeline ACUTA CAPITAL PARTNERS, LLC More: the full row for ACUTA CAPITAL PARTNERS, LLC 354,575 $5.74M 4.08% new 13F-HR Timeline Atom Investors LP More: the full row for Atom Investors LP 345,587 $5.59M 0.4% new 13F-HR Timeline KVP Capital Advisors, LP More: the full row for KVP Capital Advisors, LP 340,000 $5.5M 4.11% new 13F-HR Timeline Swiss National Bank More: the full row for Swiss National Bank 336,800 $5.45M <0.01% new 13F-HR Timeline Trexquant Investment LP More: the full row for Trexquant Investment LP 301,066 $4.87M 0.04% new 13F-HR Timeline VOYA INVESTMENT MANAGEMENT LLC in group VOYA INVESTMENT MANAGEMENT LLC More: the full row for VOYA INVESTMENT MANAGEMENT LLC 253,554 $4.1M <0.01% +220,367 13F-HR Timeline Group SIMPLEX TRADING, LLC More: the full row for SIMPLEX TRADING, LLC 252,747 $4.09M 0.13% -93,325 13F-HR Timeline Rafferty Asset Management, LLC More: the full row for Rafferty Asset Management, LLC 251,963 $4.08M 0.02% +120,944 13F-HR Timeline RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 242,636 $3.93M <0.01% +53,624 13F-HR Timeline STEMPOINT CAPITAL LP More: the full row for STEMPOINT CAPITAL LP 239,861 $3.88M 0.75% new 13F-HR/A Timeline FRED ALGER MANAGEMENT, LLC in group FRED ALGER MANAGEMENT, LLC More: the full row for FRED ALGER MANAGEMENT, LLC 236,824 $3.83M 0.02% new 13F-HR Timeline Group Tidal Investments LLC in group Tidal Investments LLC More: the full row for Tidal Investments LLC 226,877 $3.67M 0.01% new 13F-HR Timeline Group Tema ETFs LLC More: the full row for Tema ETFs LLC 226,877 $3.67M 0.25% new 13F-HR Timeline Seven Fleet Capital Management LP More: the full row for Seven Fleet Capital Management LP 222,468 $3.6M 1.13% new 13F-HR/A Timeline MANUFACTURERS LIFE INSURANCE COMPANY, T… in group MANUFACTURERS LIFE INSURANCE … More: the full row for MANUFACTURERS LIFE INSURANCE COMPANY, THE 216,614 $3.5M <0.01% +161,845 13F-HR Timeline Group SUSQUEHANNA INTERNATIONAL GROUP, LLP group of 2 filers holding More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 212,734 $3.44M -46,141 Timeline CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 204,449 $3.31M <0.01% +193,760 13F-HR Timeline TANG CAPITAL MANAGEMENT LLC in group TANG CAPITAL MANAGEMENT LLC More: the full row for TANG CAPITAL MANAGEMENT LLC 200,000 $3.24M 0.16% -700,000 13F-HR Timeline Group Pictet Asset Management Holding SA in group Pictet Asset Management Holdi… More: the full row for Pictet Asset Management Holding SA 208,273 $3.14M <0.01% new 13F-HR Timeline Group HighVista Strategies LLC More: the full row for HighVista Strategies LLC 181,069 $2.93M 0.81% new 13F-HR Timeline Cinctive Capital Management LP More: the full row for Cinctive Capital Management LP 171,920 $2.78M 0.18% new 13F-HR Timeline Longaeva Partners L.P. More: the full row for Longaeva Partners L.P. 171,233 $2.77M 0.13% new 13F-HR Timeline DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 163,326 $2.64M <0.01% +41,349 13F-HR Timeline Group NATIXIS in group Natixis Investment Managers More: the full row for NATIXIS 163,192 $2.64M 0.01% new 13F-HR Timeline Group XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 147,618 $2.39M 0.04% +136,820 13F-HR Timeline Group Informed Momentum Co LLC More: the full row for Informed Momentum Co LLC 137,925 $2.23M 0.26% new 13F-HR Timeline Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 133,444 $2.16M <0.01% +118,016 13F-HR Timeline Group Mirae Asset Global Investments Co., Ltd. group of 2 filers holding More: the full row for Mirae Asset Global Investments Co., Ltd. 122,978 $1.97M +20,959 Timeline PROFUND ADVISORS LLC More: the full row for PROFUND ADVISORS LLC 113,216 $1.83M 0.07% +62,611 13F-HR Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 107,176 $1.73M <0.01% -112,956 13F-HR/A Timeline Group MetLife Investment Management, LLC in group MetLife Investment Management… More: the full row for MetLife Investment Management, LLC 103,644 $1.68M 0.01% +23,276 13F-HR Timeline Group FRANKLIN RESOURCES INC in group Franklin Resources More: the full row for FRANKLIN RESOURCES INC 101,827 $1.65M <0.01% new 13F-HR Timeline Group Burkehill Global Management, LP More: the full row for Burkehill Global Management, LP 100,000 $1.62M 0.08% new 13F-HR Timeline SEVEN GRAND MANAGERS, LLC More: the full row for SEVEN GRAND MANAGERS, LLC 100,000 $1.62M 0.11% new 13F-HR Timeline STATE OF WISCONSIN INVESTMENT BOARD More: the full row for STATE OF WISCONSIN INVESTMENT BOARD 98,609 $1.6M <0.01% new 13F-HR Timeline J. Goldman & Co LP More: the full row for J. Goldman & Co LP 98,033 $1.59M 0.07% new 13F-HR Timeline Squarepoint Ops LLC in group Squarepoint Ops LLC More: the full row for Squarepoint Ops LLC 94,685 $1.53M <0.01% -163,590 13F-HR Timeline Group ALGERT GLOBAL LLC More: the full row for ALGERT GLOBAL LLC 88,030 $1.42M 0.02% new 13F-HR/A Timeline RAYMOND JAMES FINANCIAL INC in group RAYMOND JAMES FINANCIAL INC More: the full row for RAYMOND JAMES FINANCIAL INC 82,678 $1.34M <0.01% new 13F-HR Timeline Group Cresset Asset Management, LLC More: the full row for Cresset Asset Management, LLC 79,961 $1.29M 0.01% +48 13F-HR Timeline ArrowMark Colorado Holdings LLC More: the full row for ArrowMark Colorado Holdings LLC 79,052 $1.28M 0.03% new 13F-HR Timeline Virtus Investment Advisers, LLC in group Virtus Investment Advisers, L… More: the full row for Virtus Investment Advisers, LLC 75,746 $1.23M 0.34% +1,850 13F-HR Timeline Group Harvest Investment Services, LLC More: the full row for Harvest Investment Services, LLC 73,744 $1.19M 0.22% new 13F-HR Timeline Schonfeld Strategic Advisors LLC More: the full row for Schonfeld Strategic Advisors LLC 68,048 $1.1M 0.01% new 13F-HR Timeline Hudson Bay Capital Management LP in group Hudson Bay Capital Management… More: the full row for Hudson Bay Capital Management LP 65,350 $1.06M 0.01% -92,670 13F-HR Timeline Group State of New Jersey Common Pension Fund… in group State of New Jersey Common Pe… More: the full row for State of New Jersey Common Pension Fund D 58,176 $941K <0.01% new 13F-HR Timeline Group INTECH INVESTMENT MANAGEMENT LLC More: the full row for INTECH INVESTMENT MANAGEMENT LLC 57,533 $931K 0.01% -33,187 13F-HR Timeline GILDER GAGNON HOWE & CO LLC More: the full row for GILDER GAGNON HOWE & CO LLC 56,597 $916K 0.01% new 13F-HR Timeline Cerity Partners LLC in group Cerity Partners LLC More: the full row for Cerity Partners LLC 55,760 $902K <0.01% -5,776 13F-HR Timeline Group Brevan Howard Capital Management LP in group Brevan Howard Capital Managem… More: the full row for Brevan Howard Capital Management LP 55,104 $892K 0.01% +2,373 13F-HR Timeline Group China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 54,939 $889K 0.07% +8,708 13F-HR Timeline NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 54,759 $886K <0.01% -800 13F-HR Timeline Police & Firemen's Retirement System of… More: the full row for Police & Firemen's Retirement System of New Jersey 51,471 $833K 0.01% +7,441 13F-HR Timeline CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 49,110 $795K <0.01% -46,660 13F-HR Timeline Group Zurcher Kantonalbank (Zurich Cantonalba… More: the full row for Zurcher Kantonalbank (Zurich Cantonalbank) 47,918 $775K <0.01% new 13F-HR Timeline ARIZONA STATE RETIREMENT SYSTEM More: the full row for ARIZONA STATE RETIREMENT SYSTEM 46,757 $757K <0.01% new 13F-HR Timeline Connor, Clark & Lunn Investment Managem… More: the full row for Connor, Clark & Lunn Investment Management Ltd. 45,338 $734K <0.01% new 13F-HR Timeline BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 45,079 $729K <0.01% -357,717 13F-HR Timeline Group SG Americas Securities, LLC More: the full row for SG Americas Securities, LLC 44,697 $723K <0.01% -3,980 13F-HR Timeline MASSACHUSETTS FINANCIAL SERVICES CO /MA/ in group MASSACHUSETTS FINANCIAL SERVI… More: the full row for MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 42,340 $685K <0.01% new 13F-HR Timeline Group ProShare Advisors LLC More: the full row for ProShare Advisors LLC 41,346 $669K <0.01% -2,870 13F-HR Timeline KLP KAPITALFORVALTNING AS More: the full row for KLP KAPITALFORVALTNING AS 37,500 $607K <0.01% new 13F-HR Timeline Verdad Advisers, LP More: the full row for Verdad Advisers, LP 33,070 $535K 0.6% new 13F-HR Timeline STRS OHIO More: the full row for STRS OHIO 33,000 $534K <0.01% new 13F-HR Timeline CWM, LLC in group CWM, LLC More: the full row for CWM, LLC 32,756 $530K <0.01% -849 13F-HR Timeline Group E Fund Management Co., Ltd. More: the full row for E Fund Management Co., Ltd. 32,605 $528K 0.02% 13F-HR Timeline Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 32,305 $523K 0.01% +25,421 13F-HR Timeline Group SEI INVESTMENTS CO in group SEI INVESTMENTS CO More: the full row for SEI INVESTMENTS CO 31,760 $514K <0.01% +15,078 13F-HR Timeline Group Marks Group Wealth Management, Inc More: the full row for Marks Group Wealth Management, Inc 29,879 $483K 0.05% new 13F-HR Timeline Persistent Asset Partners Ltd More: the full row for Persistent Asset Partners Ltd 28,270 $457K 0.18% new 13F-HR Timeline STATE BOARD OF ADMINISTRATION OF FLORID… More: the full row for STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 27,777 $449K <0.01% new 13F-HR Timeline FORA Capital, LLC More: the full row for FORA Capital, LLC 26,806 $433K 0.03% new 13F-HR Timeline WEALTH ENHANCEMENT ADVISORY SERVICES, L… More: the full row for WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 23,392 $417K <0.01% +887 13F-HR Timeline Arrowpoint Investment Partners (Singapo… in group Arrowpoint Investment Partner… More: the full row for Arrowpoint Investment Partners (Singapore) Pte. Ltd. 24,847 $402K 0.58% new 13F-HR Timeline Group Quantbot Technologies LP More: the full row for Quantbot Technologies LP 23,226 $376K 0.02% new 13F-HR Timeline TEACHER RETIREMENT SYSTEM OF TEXAS More: the full row for TEACHER RETIREMENT SYSTEM OF TEXAS 22,076 $357K <0.01% new 13F-HR Timeline Quadrature Capital Ltd in group Quadrature Capital Ltd More: the full row for Quadrature Capital Ltd 21,688 $351K <0.01% +8,526 13F-HR Timeline Group Allianz Asset Management GmbH in group Allianz SE More: the full row for Allianz Asset Management GmbH 19,900 $322K <0.01% new 13F-HR Timeline Group Mariner, LLC in group Mariner, LLC More: the full row for Mariner, LLC 18,728 $303K <0.01% +7,903 13F-HR Timeline Group LANDSCAPE CAPITAL MANAGEMENT, L.L.C. in group LANDSCAPE CAPITAL MANAGEMENT,… More: the full row for LANDSCAPE CAPITAL MANAGEMENT, L.L.C. 18,736 $303K 0.02% new 13F-HR Timeline Group Scientech Research LLC More: the full row for Scientech Research LLC 18,170 $294K 0.25% -54,033 13F-HR Timeline FARALLON CAPITAL MANAGEMENT, L.L.C. More: the full row for FARALLON CAPITAL MANAGEMENT, L.L.C. 18,000 $291K <0.01% new 13F-HR Timeline The filing omitted confidential holdings, a later amendment may add them. Baader Bank Aktiengesellschaft More: the full row for Baader Bank Aktiengesellschaft 18,000 $291K 0.03% new 13F-HR Timeline XPONANCE LLC More: the full row for XPONANCE LLC 17,330 $280K <0.01% +3,840 13F-HR Timeline Odyssean, LLC More: the full row for Odyssean, LLC 17,329 $280K 0.1% new 13F-HR Timeline PSP Research LLC More: the full row for PSP Research LLC 17,327 $280K 0.2% new 13F-HR Timeline QUADRANT CAPITAL GROUP LLC More: the full row for QUADRANT CAPITAL GROUP LLC 17,073 $276K 0.01% -473 13F-HR/A Timeline Abel Hall, LLC More: the full row for Abel Hall, LLC 16,947 $274K 0.06% +1,265 13F-HR Timeline OXFORD ASSET MANAGEMENT LLP More: the full row for OXFORD ASSET MANAGEMENT LLP 16,752 $271K 0.11% new 13F-HR Timeline The filing omitted confidential holdings, a later amendment may add them. TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 15,800 $256K <0.01% -22,224 13F-HR Timeline Group Universal- Beteiligungs- und Serviceges… in group Universal- Beteiligungs- und … More: the full row for Universal- Beteiligungs- und Servicegesellschaft mbH 15,773 $255K <0.01% new 13F-HR Timeline Group Ameritas Investment Partners, Inc. in group Ameritas Investment Partners,… More: the full row for Ameritas Investment Partners, Inc. 15,524 $251K 0.01% +879 13F-HR Timeline Group Wealthcare Advisory Partners LLC in group Wealthcare Advisory Partners … More: the full row for Wealthcare Advisory Partners LLC 15,168 $245K <0.01% 0 13F-HR Timeline Group Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 14,296 $231K <0.01% -82 13F-HR Timeline Group Ballentine Partners, LLC More: the full row for Ballentine Partners, LLC 14,004 $227K <0.01% +8 13F-HR Timeline LPL Financial LLC More: the full row for LPL Financial LLC 13,292 $215K <0.01% new 13F-HR Timeline BAILARD, INC. More: the full row for BAILARD, INC. 13,146 $213K <0.01% -22,092 13F-HR Timeline ACADIAN ASSET MANAGEMENT LLC in group ACADIAN ASSET MANAGEMENT LLC More: the full row for ACADIAN ASSET MANAGEMENT LLC 12,431 $200K <0.01% new 13F-HR Timeline Group Swiss Life Asset Management Ltd in group Swiss Life Asset Management L… More: the full row for Swiss Life Asset Management Ltd 12,210 $198K <0.01% new 13F-HR Timeline Group Pallas Capital Advisors LLC More: the full row for Pallas Capital Advisors LLC 12,148 $197K 0.01% -1,777 13F-HR Timeline STIFEL FINANCIAL CORP in group STIFEL FINANCIAL CORP More: the full row for STIFEL FINANCIAL CORP 12,037 $195K <0.01% +1,737 13F-HR Timeline Group NISA INVESTMENT ADVISORS, LLC More: the full row for NISA INVESTMENT ADVISORS, LLC 11,641 $188K <0.01% +7,231 13F-HR Timeline DNB Asset Management AS in group DNB Asset Management AS More: the full row for DNB Asset Management AS 11,477 $186K <0.01% new 13F-HR Timeline Group WINTON GROUP Ltd in group WINTON GROUP Ltd More: the full row for WINTON GROUP Ltd 10,600 $172K 0.01% new 13F-HR Timeline Group ADAR1 Capital Management, LLC in group ADAR1 Capital Management, LLC More: the full row for ADAR1 Capital Management, LLC 10,000 $162K 0.01% new 13F-HR Timeline Group JONES FINANCIAL COMPANIES LLLP in group JONES FINANCIAL COMPANIES LLLP More: the full row for JONES FINANCIAL COMPANIES LLLP 9,630 $144K <0.01% new 13F-HR Timeline Group SIGNATUREFD, LLC More: the full row for SIGNATUREFD, LLC 7,397 $120K <0.01% +297 13F-HR Timeline GF FUND MANAGEMENT CO. LTD. More: the full row for GF FUND MANAGEMENT CO. LTD. 6,372 $103K <0.01% +798 13F-HR Timeline Sterling Capital Management LLC More: the full row for Sterling Capital Management LLC 6,348 $103K <0.01% -3,755 13F-HR Timeline State of Wyoming More: the full row for State of Wyoming 5,850 $94.7K 0.01% new 13F-HR Timeline KBC Group NV in group KBC Group NV More: the full row for KBC Group NV 4,996 $81K <0.01% new 13F-HR Timeline Group Sio Capital Management, LLC More: the full row for Sio Capital Management, LLC 5,000 $80.9K 0.01% new 13F-HR Timeline Parallel Advisors, LLC More: the full row for Parallel Advisors, LLC 4,295 $69.5K <0.01% +68 13F-HR/A Timeline EverSource Wealth Advisors, LLC in group EverSource Wealth Advisors, L… More: the full row for EverSource Wealth Advisors, LLC 4,249 $68.7K <0.01% +1,859 13F-HR/A Timeline Group Rockefeller Capital Management L.P. in group Rockefeller Capital Managemen… More: the full row for Rockefeller Capital Management L.P. 3,342 $54.1K <0.01% +2,686 13F-HR Timeline Group BNP PARIBAS ASSET MANAGEMENT Holding S.… in group BNP PARIBAS ASSET MANAGEMENT … More: the full row for BNP PARIBAS ASSET MANAGEMENT Holding S.A. 3,073 $49.7K <0.01% new 13F-HR Timeline Group Farther Finance Advisors, LLC More: the full row for Farther Finance Advisors, LLC 2,334 $38.7K <0.01% +6 13F-HR Timeline Kemnay Advisory Services Inc. More: the full row for Kemnay Advisory Services Inc. 2,143 $34.7K 0.01% new 13F-HR Timeline GAMMA Investing LLC More: the full row for GAMMA Investing LLC 2,004 $32.4K <0.01% +392 13F-HR Timeline Allworth Financial LP More: the full row for Allworth Financial LP 1,874 $30.3K <0.01% -74 13F-HR Timeline LOS ANGELES CAPITAL MANAGEMENT LLC More: the full row for LOS ANGELES CAPITAL MANAGEMENT LLC 1,845 $29.9K <0.01% new 13F-HR Timeline BESSEMER GROUP INC in group BESSEMER GROUP INC More: the full row for BESSEMER GROUP INC 1,587 $26K <0.01% 0 13F-HR Timeline Group PNC Financial Services Group, Inc. in group PNC Financial Services Group,… More: the full row for PNC Financial Services Group, Inc. 1,471 $23.8K <0.01% +1,463 13F-HR Timeline Group Physician Wealth Advisors, Inc. More: the full row for Physician Wealth Advisors, Inc. 1,192 $19.3K <0.01% 0 13F-HR Timeline True Wealth Design, LLC More: the full row for True Wealth Design, LLC 1,116 $18.1K 0.01% 0 13F-HR Timeline Caitong International Asset Management … More: the full row for Caitong International Asset Management Co., Ltd 1,037 $16.8K <0.01% new 13F-HR Timeline FEDERATED HERMES, INC. in group FEDERATED HERMES, INC. More: the full row for FEDERATED HERMES, INC. 1,005 $16.3K <0.01% 0 13F-HR Timeline Group E Fund Management (Hong Kong) Co., Ltd. More: the full row for E Fund Management (Hong Kong) Co., Ltd. 932 $15.1K 0.01% new 13F-HR Timeline ROTHSCHILD INVESTMENT LLC More: the full row for ROTHSCHILD INVESTMENT LLC 503 $8.14K <0.01% +109 13F-HR Timeline Optiver Holding B.V. in group Optiver Holding B.V. More: the full row for Optiver Holding B.V. 460 $7.44K <0.01% -460 13F-HR/A Timeline Group Essential Partners LLC More: the full row for Essential Partners LLC 459 $7.43K <0.01% 0 13F-HR Timeline Basecamp Wealth Advisors LLC More: the full row for Basecamp Wealth Advisors LLC 444 $7.18K <0.01% new 13F-HR Timeline Rialto Wealth Management, LLC More: the full row for Rialto Wealth Management, LLC 413 $6.68K <0.01% 0 13F-HR Timeline Cornerstone Financial Management LLC More: the full row for Cornerstone Financial Management LLC 338 $5.47K 0.01% 0 13F-HR/A Timeline US BANCORP \DE\ in group US BANCORP \DE\ More: the full row for US BANCORP \DE\ 295 $4.77K <0.01% new 13F-HR Timeline Group ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 239 $4K <0.01% -4,767 13F-HR Timeline Group