Medicxi Ventures Management (Jersey) Ltd More: the full row for Medicxi Ventures Management (Jersey) Ltd 19,963,157 $334M 63.2% 0 13F-HR Timeline Index Venture Life Associates VI Ltd More: the full row for Index Venture Life Associates VI Ltd 9,961,789 $167M 99.89% 13F-HR Timeline GENERAL ATLANTIC, L.P. More: the full row for GENERAL ATLANTIC, L.P. 9,681,818 $162M 5.77% 0 13F-HR Timeline PERCEPTIVE ADVISORS LLC in group PERCEPTIVE ADVISORS LLC More: the full row for PERCEPTIVE ADVISORS LLC 6,349,220 $106M 2.96% +66,930 13F-HR Timeline Group First Light Asset Management, LLC More: the full row for First Light Asset Management, LLC 5,805,184 $97.2M 9.3% -134,948 13F-HR Timeline PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 5,364,392 $89.9M 0.01% +685,371 13F-HR Timeline ADAGE CAPITAL PARTNERS GP, L.L.C. in group ADAGE CAPITAL PARTNERS GP, L.… More: the full row for ADAGE CAPITAL PARTNERS GP, L.L.C. 5,119,027 $85.7M 0.15% +924,027 13F-HR Timeline Group JANUS HENDERSON GROUP PLC in group Janus Henderson More: the full row for JANUS HENDERSON GROUP PLC 4,909,487 $82.2M 0.04% +3,614,623 13F-HR Timeline Group Vida Ventures Advisors, LLC More: the full row for Vida Ventures Advisors, LLC 3,931,818 $65.9M 45.01% 0 13F-HR Timeline FMR LLC in group FMR LLC More: the full row for FMR LLC 3,651,594 $61.2M <0.01% +735,100 13F-HR Timeline Group FARALLON CAPITAL MANAGEMENT, L.L.C. More: the full row for FARALLON CAPITAL MANAGEMENT, L.L.C. 3,498,709 $58.6M 0.31% +684,391 13F-HR Timeline Point72 Asset Management, L.P. in group Point72 Asset Management, L.P. More: the full row for Point72 Asset Management, L.P. 3,426,599 $57.4M 0.16% +710,936 13F-HR Timeline Group T. Rowe Price Investment Management, In… More: the full row for T. Rowe Price Investment Management, Inc. 3,418,600 $57.3M 0.04% -137,423 13F-HR Timeline Siren, L.L.C. in group Siren, L.L.C. More: the full row for Siren, L.L.C. 3,004,677 $50.3M 2.22% -254,000 13F-HR Timeline Group TCG Crossover Management, LLC More: the full row for TCG Crossover Management, LLC 2,890,816 $48.4M 4.73% 0 13F-HR Timeline Cormorant Asset Management, LP More: the full row for Cormorant Asset Management, LP 2,561,600 $42.9M 2.36% 0 13F-HR Timeline FRANKLIN RESOURCES INC in group Franklin Resources More: the full row for FRANKLIN RESOURCES INC 2,308,546 $38.7M 0.01% +6,000 13F-HR Timeline Group Commodore Capital LP in group Commodore Capital LP More: the full row for Commodore Capital LP 2,218,425 $37.2M 2.72% +868,425 13F-HR Timeline Group Octagon Capital Advisors LP More: the full row for Octagon Capital Advisors LP 1,993,052 $33.4M 5.68% -19,000 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 1,924,509 $32.2M <0.01% +544,858 13F-HR/A Timeline Group Driehaus Capital Management LLC More: the full row for Driehaus Capital Management LLC 1,598,183 $26.8M 0.22% -563,545 13F-HR Timeline Deep Track Capital, LP More: the full row for Deep Track Capital, LP 1,350,000 $22.6M 0.85% 0 13F-HR Timeline Foresite Capital Management VI LLC in group Foresite Capital Management V… More: the full row for Foresite Capital Management VI LLC 1,253,379 $21M 9.35% 13F-HR Timeline Group BAKER BROS. ADVISORS LP in group BAKER BROS. ADVISORS LP More: the full row for BAKER BROS. ADVISORS LP 1,227,178 $20.6M 0.22% 0 13F-HR Timeline Group Avidity Partners Management LP More: the full row for Avidity Partners Management LP 1,165,800 $19.5M 1.95% -966,200 13F-HR Timeline Affinity Asset Advisors, LLC More: the full row for Affinity Asset Advisors, LLC 1,095,924 $18.4M 2.87% +130,312 13F-HR Timeline AMERICAN CENTURY COMPANIES INC in group AMERICAN CENTURY COMPANIES INC More: the full row for AMERICAN CENTURY COMPANIES INC 1,079,708 $18.1M 0.01% -59,838 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 1,070,209 $17.9M <0.01% +1,065,202 13F-HR Timeline Group 5AM Venture Management, LLC More: the full row for 5AM Venture Management, LLC 830,945 $13.9M 3.32% -454,055 13F-HR Timeline Tanager Wealth Management LLP More: the full row for Tanager Wealth Management LLP 696,096 $11.7M 1.51% 0 13F-HR Timeline STEMPOINT CAPITAL LP More: the full row for STEMPOINT CAPITAL LP 641,964 $10.8M 2.7% +558,302 13F-HR Timeline TD Asset Management Inc More: the full row for TD Asset Management Inc 641,714 $10.7M 0.01% +83,000 13F-HR Timeline CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 625,316 $10.5M 0.01% +37,798 13F-HR Timeline Group SILVERARC CAPITAL MANAGEMENT, LLC in group SILVERARC CAPITAL MANAGEMENT,… More: the full row for SILVERARC CAPITAL MANAGEMENT, LLC 598,952 $10M 2.24% -145,640 13F-HR Timeline Group Woodline Partners LP More: the full row for Woodline Partners LP 545,645 $9.14M 0.06% +29,266 13F-HR Timeline Nantahala Capital Management, LLC in group Nantahala Capital Management,… More: the full row for Nantahala Capital Management, LLC 512,647 $8.59M 0.6% 0 13F-HR Timeline Group BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 500,924 $8.39M <0.01% -58,796 13F-HR Timeline Group LORD, ABBETT & CO. LLC More: the full row for LORD, ABBETT & CO. LLC 440,495 $7.38M 0.02% +171,290 13F-HR Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 398,451 $6.67M 0.01% +168,072 13F-HR Timeline Group PFM Health Sciences, LP More: the full row for PFM Health Sciences, LP 371,766 $6.23M 0.47% +102,608 13F-HR Timeline PLATINUM INVESTMENT MANAGEMENT LTD More: the full row for PLATINUM INVESTMENT MANAGEMENT LTD 370,278 $6.2M 0.36% -59,423 13F-HR Timeline Schonfeld Strategic Advisors LLC More: the full row for Schonfeld Strategic Advisors LLC 365,200 $6.12M 0.04% new 13F-HR Timeline MANUFACTURERS LIFE INSURANCE COMPANY, T… in group MANUFACTURERS LIFE INSURANCE … More: the full row for MANUFACTURERS LIFE INSURANCE COMPANY, THE 317,329 $5.32M <0.01% +52,360 13F-HR Timeline Group DZ BANK AG Deutsche Zentral Genossensch… in group DZ BANK AG Deutsche Zentral G… More: the full row for DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main 303,479 $5.08M 0.01% new 13F-HR Timeline Group Allostery Investments LP More: the full row for Allostery Investments LP 284,517 $4.77M 9.36% 13F-HR Timeline Trexquant Investment LP More: the full row for Trexquant Investment LP 261,184 $4.37M 0.05% +90,233 13F-HR Timeline Ally Bridge Group (NY) LLC More: the full row for Ally Bridge Group (NY) LLC 244,538 $4.1M 3.51% -65,076 13F-HR Timeline Blue Owl Capital Holdings LP More: the full row for Blue Owl Capital Holdings LP 220,000 $3.69M 0.85% -35,000 13F-HR Timeline FRED ALGER MANAGEMENT, LLC in group FRED ALGER MANAGEMENT, LLC More: the full row for FRED ALGER MANAGEMENT, LLC 190,451 $3.19M 0.02% +12,898 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 190,385 $3.19M <0.01% +54,482 13F-HR Timeline Group RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 178,600 $2.99M <0.01% -31,000 13F-HR Timeline GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 175,566 $2.94M <0.01% +162,511 13F-HR Timeline Group Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 175,428 $2.94M 0.01% -505,993 13F-HR Timeline Group HighMark Wealth Management LLC More: the full row for HighMark Wealth Management LLC 166,135 $2.78M 1.6% -1,000 13F-HR Timeline J. Goldman & Co LP More: the full row for J. Goldman & Co LP 164,703 $2.76M 0.1% new 13F-HR Timeline ADAR1 Capital Management, LLC in group ADAR1 Capital Management, LLC More: the full row for ADAR1 Capital Management, LLC 154,027 $2.58M 0.53% +130,725 13F-HR Timeline Group Cutter Capital Management, LP More: the full row for Cutter Capital Management, LP 147,076 $2.46M 1.01% new 13F-HR Timeline MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 139,732 $2.34M <0.01% -41,121 13F-HR Timeline Group Exome Asset Management LLC More: the full row for Exome Asset Management LLC 137,716 $2.31M 1.74% -436 13F-HR Timeline DIADEMA PARTNERS LP More: the full row for DIADEMA PARTNERS LP 131,862 $2.21M 2.49% 13F-HR Timeline WELLINGTON MANAGEMENT GROUP LLP in group WELLINGTON MANAGEMENT GROUP L… More: the full row for WELLINGTON MANAGEMENT GROUP LLP 115,107 $1.93M <0.01% +14,494 13F-HR Timeline Group Qube Research & Technologies Ltd More: the full row for Qube Research & Technologies Ltd 107,058 $1.79M <0.01% +10,543 13F-HR Timeline Artia Global Partners LP More: the full row for Artia Global Partners LP 80,380 $1.35M 0.54% 0 13F-HR Timeline Ensign Peak Advisors, Inc More: the full row for Ensign Peak Advisors, Inc 79,000 $1.32M <0.01% 0 13F-HR Timeline Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 75,451 $1.26M <0.01% new 13F-HR Timeline Group LAZARD ASSET MANAGEMENT LLC in group LAZARD ASSET MANAGEMENT LLC More: the full row for LAZARD ASSET MANAGEMENT LLC 73,189 $1.23M <0.01% new 13F-HR Timeline Group GSA CAPITAL PARTNERS LLP More: the full row for GSA CAPITAL PARTNERS LLP 71,947 $1.21M 0.09% -21,711 13F-HR Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 57,257 $959K <0.01% +660 13F-HR Timeline Group RTW INVESTMENTS, LP More: the full row for RTW INVESTMENTS, LP 50,000 $838K 0.01% 0 13F-HR Timeline STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 48,106 $806K <0.01% -486 13F-HR Timeline Group DAFNA Capital Management LLC More: the full row for DAFNA Capital Management LLC 47,453 $795K 0.2% -72,898 13F-HR Timeline HighVista Strategies LLC More: the full row for HighVista Strategies LLC 46,116 $772K 0.29% 0 13F-HR Timeline Cubist Systematic Strategies, LLC More: the full row for Cubist Systematic Strategies, LLC 45,885 $769K 0.01% -88,235 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 43,708 $732K <0.01% -269,630 13F-HR Timeline Group BOOTHBAY FUND MANAGEMENT, LLC More: the full row for BOOTHBAY FUND MANAGEMENT, LLC 41,900 $702K 0.02% new 13F-HR Timeline Persistent Asset Partners Ltd More: the full row for Persistent Asset Partners Ltd 37,701 $638K 0.55% 13F-HR Timeline TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 37,900 $635K <0.01% -66,008 13F-HR Timeline Group Verition Fund Management LLC More: the full row for Verition Fund Management LLC 36,195 $606K <0.01% new 13F-HR Timeline PRELUDE CAPITAL MANAGEMENT, LLC More: the full row for PRELUDE CAPITAL MANAGEMENT, LLC 35,800 $600K 0.05% -1,100 13F-HR Timeline VOYA INVESTMENT MANAGEMENT LLC in group VOYA INVESTMENT MANAGEMENT LLC More: the full row for VOYA INVESTMENT MANAGEMENT LLC 29,670 $497K <0.01% new 13F-HR/A Timeline Group Squarepoint Ops LLC in group Squarepoint Ops LLC More: the full row for Squarepoint Ops LLC 26,806 $449K <0.01% +6,685 13F-HR Timeline Group Jump Financial, LLC in group Jump Financial, LLC More: the full row for Jump Financial, LLC 25,700 $430K 0.01% -23,411 13F-HR Timeline Group Jain Global LLC More: the full row for Jain Global LLC 23,466 $393K 0.01% 13F-HR Timeline XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 22,680 $380K 0.03% +12,506 13F-HR Timeline Group AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 19,122 $320K <0.01% new 13F-HR Timeline Group China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 18,909 $317K 0.03% +5,316 13F-HR Timeline Lynx1 Capital Management LP in group Lynx1 Capital Management LP More: the full row for Lynx1 Capital Management LP 17,400 $291K 0.11% 0 13F-HR Timeline Group Atom Investors LP More: the full row for Atom Investors LP 17,197 $288K 0.04% new 13F-HR Timeline Rathbones Group PLC More: the full row for Rathbones Group PLC 16,650 $279K <0.01% -13,750 13F-HR Timeline Harbour Capital Advisors, LLC More: the full row for Harbour Capital Advisors, LLC 16,375 $279K 0.06% -300 13F-HR Timeline SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 15,746 $264K <0.01% -12,138 13F-HR Timeline Group Shay Capital LLC More: the full row for Shay Capital LLC 14,269 $239K 0.06% new 13F-HR Timeline Atria Investments, Inc More: the full row for Atria Investments, Inc 13,774 $231K <0.01% -3,360 13F-HR Timeline OMERS ADMINISTRATION Corp More: the full row for OMERS ADMINISTRATION Corp 10,200 $171K <0.01% new 13F-HR Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 9,672 $162K <0.01% new 13F-HR Timeline Group ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 8,343 $139K <0.01% +2,064 13F-HR Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 5,302 $88.8K <0.01% +4,952 13F-HR/A Timeline Group VIRTUS ADVISERS, LLC in group Virtus Investment Advisers, L… More: the full row for VIRTUS ADVISERS, LLC 4,214 $70.6K 0.03% -5,071 13F-HR Timeline Group GAMMA Investing LLC More: the full row for GAMMA Investing LLC 3,837 $64.3K 0.01% +865 13F-HR Timeline Mirae Asset Global Investments Co., Ltd. in group Mirae Asset Global Investment… More: the full row for Mirae Asset Global Investments Co., Ltd. 2,972 $50.4K <0.01% +416 13F-HR Timeline Group Advisors Preferred, LLC in group Advisors Preferred, LLC More: the full row for Advisors Preferred, LLC 2,372 $41.5K 0.01% -2,183 13F-HR Timeline Group GF FUND MANAGEMENT CO. LTD. More: the full row for GF FUND MANAGEMENT CO. LTD. 1,872 $31.4K <0.01% 13F-HR Timeline Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 1,861 $31.2K <0.01% -428 13F-HR Timeline Group Zurcher Kantonalbank (Zurich Cantonalba… More: the full row for Zurcher Kantonalbank (Zurich Cantonalbank) 1,813 $30.4K <0.01% -386 13F-HR Timeline ACADIAN ASSET MANAGEMENT LLC in group ACADIAN ASSET MANAGEMENT LLC More: the full row for ACADIAN ASSET MANAGEMENT LLC 1,457 $24K <0.01% new 13F-HR Timeline Group CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 1,179 $19.7K <0.01% -12,915 13F-HR Timeline Group R Squared Ltd More: the full row for R Squared Ltd 990 $16.6K 0.02% 13F-HR Timeline ADIRONDACK TRUST CO More: the full row for ADIRONDACK TRUST CO 925 $15.5K 0.01% 0 13F-HR Timeline Global Retirement Partners, LLC More: the full row for Global Retirement Partners, LLC 700 $11.7K <0.01% 0 13F-HR Timeline NATIONAL BANK OF CANADA /FI/ in group NATIONAL BANK OF CANADA /FI/ More: the full row for NATIONAL BANK OF CANADA /FI/ 600 $10.1K <0.01% new 13F-HR Timeline Group Daiwa Securities Group Inc. in group Daiwa Securities Group Inc. More: the full row for Daiwa Securities Group Inc. 294 $5K <0.01% +83 13F-HR Timeline Group CALDWELL SUTTER CAPITAL, INC. More: the full row for CALDWELL SUTTER CAPITAL, INC. 43 $720 <0.01% -43 13F-HR Timeline Bell Investment Advisors, Inc More: the full row for Bell Investment Advisors, Inc 31 $520 <0.01% new 13F-HR Timeline Caitong International Asset Management … More: the full row for Caitong International Asset Management Co., Ltd 21 $352 <0.01% 13F-HR/A Timeline CONCOURSE FINANCIAL GROUP SECURITIES, I… More: the full row for CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0 $0 0% 0 13F-HR Timeline Value filed as zero, left out of ratios. Amount filed as zero, left out of ratios.