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BRAIDWELL LP

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13F filer, CIK 1920938, STAMFORD, CT

BRAIDWELL LP reported $3,126,999,740 across 73 holdings for the quarter ended 2025-12-31, in a 13F-HR filed 2026-02-17. Its ten largest share positions make up 37.92% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001420506-26-000586

Period
2025-12-31
Reported value
$3.13B
Holdings
73
Top 10 weight
37.92%
New
20
Sold out
20

Largest buys vs the previous quarter

SecurityShares changeApprox. value
KODnew+2,072,788$58M
CNTAnew+2,188,320$54.7M
BTSGnew+1,195,786$44.8M
NRIXnew+2,183,864$41.4M
ILMNnew+269,673$35.4M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
XENEreduced-1,779,953-$79.8M
KRYSreduced-318,300-$78.5M
APGEreduced-863,678-$65.2M
CGONreduced-1,412,746-$58.7M
DHRreduced-191,112-$43.7M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q4 2025

Share positions as resolved from 13F-HR 0001420506-26-000586, largest first. % of portfolio is the value over $3,126,999,740, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
CAICARIS LIFE SCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 7,316,142 shares; 2025Q3: 7,316,142 shares; 2025Q4: 7,816,142 shares 7,816,142$211M6.74%+500,000Timeline
EWTXEDGEWISE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,958,310 shares; 2024Q4: 2,332,196 shares; 2025Q1: 2,458,808 shares; 2025Q2: 5,210,831 shares; 2025Q3: 5,210,831 shares; 2025Q4: 5,210,831 shares 5,210,831$129M4.14%0Timeline
NBIXNEUROCRINE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 917,674 shares; 2024Q4: 901,790 shares; 2025Q1: 1,191,925 shares; 2025Q2: 1,160,425 shares; 2025Q3: 880,282 shares; 2025Q4: 751,534 shares 751,534$107M3.41%-128,748Timeline
GKOSGLAUKOS CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 311,616 shares; 2024Q4: 288,876 shares; 2025Q1: 624,435 shares; 2025Q2: 603,414 shares; 2025Q3: 780,164 shares; 2025Q4: 921,979 shares 921,979$104M3.33%+141,815Timeline
NUVLNUVALENT INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 241,235 shares; 2025Q1: 840,945 shares; 2025Q2: 1,175,876 shares; 2025Q3: 1,012,982 shares; 2025Q4: 821,406 shares 821,406$82.6M2.64%-191,576Timeline
XENEXENON PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,707,255 shares; 2024Q4: 2,913,964 shares; 2025Q1: 2,709,875 shares; 2025Q2: 3,605,029 shares; 2025Q3: 3,605,029 shares; 2025Q4: 1,825,076 shares 1,825,076$81.8M2.62%-1,779,953Timeline
CGONCG ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,170,875 shares; 2024Q4: 3,283,317 shares; 2025Q1: 3,283,317 shares; 2025Q2: 3,283,317 shares; 2025Q3: 3,283,317 shares; 2025Q4: 1,870,571 shares 1,870,571$77.7M2.48%-1,412,746Timeline
HNGEHINGE HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 910,476 shares; 2025Q4: 1,304,623 shares 1,304,623$60.6M1.94%+394,147Timeline
ALGNALIGN TECHNOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 311,679 shares; 2024Q4: 375,179 shares; 2025Q1: 530,530 shares; 2025Q2: 496,730 shares; 2025Q3: 409,691 shares; 2025Q4: 381,004 shares 381,004$59.5M1.9%-28,687Timeline
KODKODIAK SCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 2,072,788 shares 2,072,788$58M1.85%newTimeline
SLNOSOLENO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,281,989 shares; 2025Q4: 1,187,859 shares 1,187,859$55M1.76%-94,130Timeline
CNTACENTESSA PHARMACEUTICALS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 2,188,320 shares 2,188,320$54.7M1.75%newTimeline
NEONEOGENOMICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,771,146 shares; 2025Q4: 4,632,801 shares 4,632,801$54.5M1.74%+2,861,655Timeline
ACADACADIA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 2,378,655 shares; 2025Q4: 2,032,021 shares 2,032,021$54.3M1.74%-346,634Timeline
SYRESPYRE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,189,836 shares; 2024Q4: 2,578,404 shares; 2025Q1: 2,578,404 shares; 2025Q2: 2,578,404 shares; 2025Q3: 2,578,404 shares; 2025Q4: 1,634,615 shares 1,634,615$53.5M1.71%-943,789Timeline
DNTHDIANTHUS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 493,687 shares; 2024Q4: 1,206,589 shares; 2025Q1: 375,355 shares; 2025Q2: not reported; 2025Q3: 835,057 shares; 2025Q4: 1,273,935 shares 1,273,935$52.5M1.68%+438,878Timeline
CLDXCELLDEX THERAPEUTICS INC NEWQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 591,689 shares; 2025Q4: 1,858,109 shares 1,858,109$50.5M1.61%+1,266,420Timeline
INSPINSPIRE MED SYS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 238,911 shares; 2024Q4: 293,410 shares; 2025Q1: 302,410 shares; 2025Q2: 522,410 shares; 2025Q3: 883,747 shares; 2025Q4: 540,890 shares 540,890$49.9M1.6%-342,857Timeline
KRYSKRYSTAL BIOTECH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 168,691 shares; 2024Q4: 200,500 shares; 2025Q1: 400,744 shares; 2025Q2: 727,811 shares; 2025Q3: 520,401 shares; 2025Q4: 202,101 shares 202,101$49.8M1.59%-318,300Timeline
ISRGINTUITIVE SURGICAL INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 91,300 shares; 2024Q4: 75,300 shares; 2025Q1: 88,000 shares; 2025Q2: 89,600 shares; 2025Q3: 130,227 shares; 2025Q4: 83,417 shares 83,417$47.2M1.51%-46,810Timeline
TMOTHERMO FISHER SCIENTIFIC INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 89,754 shares; 2025Q1: 127,733 shares; 2025Q2: 135,233 shares; 2025Q3: 113,933 shares; 2025Q4: 80,725 shares 80,725$46.8M1.5%-33,208Timeline
BTSGBRIGHTSPRING HEALTH SVCS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,195,786 shares 1,195,786$44.8M1.43%newTimeline
CVSCVS HEALTH CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 438,600 shares; 2025Q4: 564,200 shares 564,200$44.8M1.43%+125,600Timeline
APGEAPOGEE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,643,226 shares; 2024Q4: 1,540,362 shares; 2025Q1: 1,540,362 shares; 2025Q2: 1,478,512 shares; 2025Q3: 1,438,745 shares; 2025Q4: 575,067 shares 575,067$43.4M1.39%-863,678Timeline
NRIXNURIX THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 2,183,864 shares 2,183,864$41.4M1.32%newTimeline
VERAVERA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 472,739 shares; 2025Q4: 784,742 shares 784,742$39.7M1.27%+312,003Timeline
IRTCIRHYTHM HOLDINGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 782,557 shares; 2024Q4: 705,391 shares; 2025Q1: 556,391 shares; 2025Q2: 300,029 shares; 2025Q3: 225,845 shares; 2025Q4: 217,345 shares 217,345$38.6M1.23%-8,500Timeline
TMDXTRANSMEDICS GROUP INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 922,100 shares; 2025Q1: 854,884 shares; 2025Q2: 255,048 shares; 2025Q3: 351,248 shares; 2025Q4: 315,341 shares 315,341$38.4M1.23%-35,907Timeline
BMRNBIOMARIN PHARMACEUTICAL INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 528,000 shares; 2025Q4: 601,520 shares 601,520$35.7M1.14%+73,520Timeline
ILMNILLUMINA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 269,673 shares 269,673$35.4M1.13%newTimeline
KYMRKYMERA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 276,692 shares; 2025Q4: 454,259 shares 454,259$35.3M1.13%+177,567Timeline
FULCFULCRUM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,069,158 shares; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 219,488 shares; 2025Q4: 3,061,222 shares 3,061,222$34.6M1.11%+2,841,734Timeline
PENPENUMBRA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 361,428 shares; 2024Q4: 183,828 shares; 2025Q1: 110,128 shares; 2025Q2: 129,628 shares; 2025Q3: 141,528 shares; 2025Q4: 110,152 shares 110,152$34.2M1.1%-31,376Timeline
MBXMBX BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,018,600 shares 1,018,600$32.1M1.03%newTimeline
RAPTRAPT THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 929,694 shares 929,694$31.5M1.01%newTimeline
CDNACAREDX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 2,182,781 shares; 2025Q4: 1,585,220 shares 1,585,220$29.9M0.96%-597,561Timeline
DYNDYNE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 681,182 shares; 2025Q1: 3,621,344 shares; 2025Q2: 3,273,349 shares; 2025Q3: 2,730,481 shares; 2025Q4: 1,478,329 shares 1,478,329$28.9M0.92%-1,252,152Timeline
ENGNENGENE HOLDINGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 2,266,319 shares; 2025Q4: 3,131,319 shares 3,131,319$28.3M0.9%+865,000Timeline
LEGNLEGEND BIOTECH CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,541,551 shares; 2024Q4: 2,977,951 shares; 2025Q1: 2,977,951 shares; 2025Q2: 2,542,104 shares; 2025Q3: 1,826,155 shares; 2025Q4: 1,298,142 shares 1,298,142$28.2M0.9%-528,013Timeline
MRVIMARAVAI LIFESCIENCES HLDGS IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 8,353,287 shares; 2024Q4: 8,353,287 shares; 2025Q1: 8,353,287 shares; 2025Q2: 8,353,287 shares; 2025Q3: 8,353,287 shares; 2025Q4: 8,353,287 shares 8,353,287$27.1M0.87%0Timeline
DHRDANAHER CORP DELQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 309,339 shares; 2025Q2: 309,339 shares; 2025Q3: 309,339 shares; 2025Q4: 118,227 shares 118,227$27.1M0.87%-191,112Timeline
ARGXARGENX SEQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 96,724 shares; 2024Q4: 80,766 shares; 2025Q1: 160,849 shares; 2025Q2: 194,491 shares; 2025Q3: 76,091 shares; 2025Q4: 31,007 shares 31,007$26.1M0.83%-45,084Timeline
NTRANATERA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 111,500 shares 111,500$25.5M0.82%newTimeline
DRUGBRIGHT MINDS BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 303,685 shares; 2025Q4: 324,358 shares 324,358$25.3M0.81%+20,673Timeline
TERNTERNS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 575,321 shares 575,321$23.2M0.74%newTimeline
EOLSEVOLUS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 3,105,209 shares 3,105,209$20.6M0.66%newTimeline
BIIBBIOGEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 115,700 shares 115,700$20.4M0.65%newTimeline
KIDSORTHOPEDIATRICS CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,107,770 shares; 2024Q4: 1,107,770 shares; 2025Q1: 1,107,770 shares; 2025Q2: 1,107,770 shares; 2025Q3: 1,107,770 shares; 2025Q4: 1,100,370 shares 1,100,370$19.5M0.62%-7,400Timeline
TECXTECTONIC THERAPEUTIC INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 736,867 shares; 2025Q4: 927,524 shares 927,524$19.3M0.62%+190,657Timeline
VTYXVENTYX BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,920,255 shares 1,920,255$17.3M0.55%newTimeline
ZURAZURA BIO LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,472,806 shares; 2024Q4: 2,472,806 shares; 2025Q1: 2,472,806 shares; 2025Q2: 2,472,806 shares; 2025Q3: 2,472,806 shares; 2025Q4: 3,180,389 shares 3,180,389$16.7M0.53%+707,583Timeline
CMPXCOMPASS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 2,786,778 shares 2,786,778$15M0.48%newTimeline
GLUEMONTE ROSA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 948,316 shares 948,316$14.9M0.48%newTimeline
HROWHARROW INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 439,638 shares; 2024Q4: 907,039 shares; 2025Q1: 956,839 shares; 2025Q2: 872,246 shares; 2025Q3: 342,391 shares; 2025Q4: 295,291 shares 295,291$14.5M0.46%-47,100Timeline
XFORX4 PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 3,368,904 shares 3,368,904$13.5M0.43%newTimeline
RGENREPLIGEN CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 396,781 shares; 2024Q4: 283,823 shares; 2025Q1: 81,656 shares; 2025Q2: 144,556 shares; 2025Q3: 195,656 shares; 2025Q4: 81,790 shares 81,790$13.4M0.43%-113,866Timeline
ICLRICON PUB LTD COQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 73,370 shares 73,370$13.4M0.43%newTimeline
KNSAKINIKSA PHARMACEUTICALS INTLQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,894,513 shares; 2024Q4: 3,452,447 shares; 2025Q1: 1,962,909 shares; 2025Q2: 1,102,580 shares; 2025Q3: 643,180 shares; 2025Q4: 313,823 shares 313,823$12.9M0.41%-329,357Timeline
GRALGRAIL INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 142,755 shares 142,755$12.2M0.39%newTimeline
SRZNSURROZEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 140,000 shares; 2025Q3: 140,000 shares; 2025Q4: 470,000 shares 470,000$10.6M0.34%+330,000Timeline
RLMDRELMADA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 1,582,257 shares 1,582,257$7.64M0.24%newTimeline
XNCRXENCOR INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 466,448 shares; 2024Q4: 615,531 shares; 2025Q1: 1,655,690 shares; 2025Q2: 1,655,690 shares; 2025Q3: 1,246,280 shares; 2025Q4: 459,166 shares 459,166$7.03M0.22%-787,114Timeline
CSTLCASTLE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 331,986 shares; 2024Q4: not reported; 2025Q1: 365,247 shares; 2025Q2: 822,735 shares; 2025Q3: 822,735 shares; 2025Q4: 177,183 shares 177,183$6.89M0.22%-645,552Timeline
ADPTADAPTIVE BIOTECHNOLOGIES CORQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 4,803,794 shares; 2025Q2: 3,863,107 shares; 2025Q3: 736,014 shares; 2025Q4: 311,991 shares 311,991$5.07M0.16%-424,023Timeline
BLLNBILLIONTOONE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 50,000 shares 50,000$4.09M0.13%newTimeline
ORKAORUKA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 515,726 shares; 2024Q4: 1,147,676 shares; 2025Q1: 1,572,426 shares; 2025Q2: 1,524,842 shares; 2025Q3: 1,382,350 shares; 2025Q4: 84,795 shares 84,795$2.57M0.08%-1,297,555Timeline
KPTIKARYOPHARM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 303,370 shares 303,370$2.23M0.07%newTimeline
LUNGPULMONX CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 752,541 shares; 2024Q4: 752,541 shares; 2025Q1: 752,541 shares; 2025Q2: 752,541 shares; 2025Q3: 752,541 shares; 2025Q4: 752,541 shares 752,541$1.66M0.05%0Timeline

Principal amounts

Notes and convertibles filed as a face amount (PRN). A face amount is never added to a share count (H6).

SecurityTypeAmountValueChange
GUARDANT HEALTH INCGUARDANT HEALTH INC DEBT 1.250% 2/1principal104,854,000$192M-114,600,000
REPLIGEN CORPREPLIGEN CORP NOTE 1.000%12/1principal101,000,000$111M0
NEOGENOMICS INCNEOGENOMICS INC NOTE 0.250% 1/1principal100,381,000$89.7M0
IRHYTHM HOLDINGS INCIRHYTHM HOLDINGS INC NOTE 1.500% 9/0principal52,000,000$72.8M-10,000,000
IRONWOOD PHARMACEUTICALS INCIRONWOOD PHARMACEUTICALS INC NOTE 1.500% 6/1principal53,405,000$50.5M-28,735,000

Sold out in Q4 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
NOVOCURE LTDNOVOCURE LTD211,364,000$210Mprincipal
KARYOPHARM THERAPEUTICS INCKARYOPHARM THERAPEUTICS INC48,482,000$35Mprincipal
GMEDGLOBUS MED INC498,000$28.5Mshares
THCTENET HEALTHCARE CORP121,700$24.7Mshares
EXASEXACT SCIENCES CORP414,600$22.7Mshares
AKROAKERO THERAPEUTICS INC475,400$22.6Mshares
ATECALPHATEC HLDGS INC1,514,604$22Mshares
VKTXVIKING THERAPEUTICS INC759,455$20Mshares
RAREULTRAGENYX PHARMACEUTICAL IN588,700$17.7Mshares
SRPTSAREPTA THERAPEUTICS INC832,100$16Mshares
DAWNDAY ONE BIOPHARMACEUTICALS I2,181,598$15.4Mshares
RNAMAVIDITY BIOSCIENCES INC331,907$14.5Mshares
EHCENCOMPASS HEALTH CORP113,335$14.4Mshares
DEXCOM INCDEXCOM INC13,500,000$13.4Mprincipal
REPLREPLIMUNE GROUP INC2,750,092$11.5Mshares
SIONSIONNA THERAPEUTICS INC314,013$9.24Mshares
AMLXAMYLYX PHARMACEUTICALS INC612,841$8.33Mshares
RPRXROYALTY PHARMA PLC182,068$6.42Mshares
IMMUNOCORE HLDGS PLCIMMUNOCORE HLDGS PLC6,828,000$6.19Mprincipal
HTFLHEARTFLOW INC50,000$1.68Mshares

How Q4 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001420506-26-000586 base2026-02-17acceptance time not in the bulk data set