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Disclosery

VTYX VENTYX BIOSCIENCES INC

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Common Stock (common)

135 managers (139 13F filers) reported a position in VTYX shares at 2025-12-31, 52,225,382 shares in all. 47 filers opened a position and 22 filers sold out during the quarter.

Managers
135
13F filers
139
New
47
Added
30
Reduced
41
Sold out
22
Shares held by filers
52,225,382

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Affinity Asset Advisors, LLC6,484,558$58.6M4.21%+2,560,14313F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY4,292,951$38.8M<0.01%+4,049,19413F-HR/ATimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding3,990,127$36M+172,835Timeline
BlackRock, Inc.in group BlackRock, Inc.3,142,440$28.4M<0.01%+1,959,20013F-HRTimelineGroup
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC2,814,000$25.4M1.26%-286,00013F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP2,349,280$21.2M0.12%+1,326,15013F-HRTimelineGroup
BRAIDWELL LP1,920,255$17.3M0.55%new13F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.1,665,474$15M0.01%+1,142,78613F-HRTimelineGroup
MPM BIOIMPACT LLC1,639,061$14.8M1.69%new13F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC1,563,611$14.1M0.01%-316,37813F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 3 filers holding1,287,159$11.6M+417,520Timeline
Connor, Clark & Lunn Investment Managem…1,203,997$10.9M0.03%+144,17413F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.1,056,520$9.54M0.01%-2,153,12513F-HRTimelineGroup
683 Capital Management, LLCin group 683 Capital Management, LLC1,040,000$9.39M0.78%+40,00013F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC989,917$8.94M0.01%-661,87713F-HRTimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC958,704$8.66M1.12%-350,90013F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC941,067$8.5M0.01%+555,96313F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC837,602$7.56M<0.01%+430,69113F-HR/ATimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC773,512$6.98M0.01%+69,71213F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP742,544$6.7M<0.01%+321,20313F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management735,711$6.64M0.01%new13F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC722,355$6.53M<0.01%-6,36513F-HRTimelineGroup
Artia Global Partners LP695,982$6.28M1.01%new13F-HRTimeline
TUDOR INVESTMENT CORP ET AL583,611$5.27M0.03%new13F-HRTimeline
STATE STREET CORPin group STATE STREET CORP548,743$4.96M<0.01%+261,00213F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC538,071$4.86M0.01%+303,07113F-HRTimeline
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding515,530$4.66M-236,152Timeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS452,310$4.08M<0.01%+452,06913F-HRTimelineGroup
NOMURA ASSET MANAGEMENT INTERNATIONAL I…in group NOMURA ASSET MANAGEMENT CO LTD430,000$3.88M0.01%13F-HRTimelineGroup
Squadron Capital Management LLC410,000$3.7M1.65%13F-HRTimeline
Sio Capital Management, LLC387,751$3.5M0.58%-441,42713F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co383,231$3.46M<0.01%-14,35813F-HRTimelineGroup
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…375,000$3.39M0.01%new13F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/316,856$2.86M<0.01%-212,39313F-HRTimelineGroup
TCG Crossover Management, LLC316,195$2.86M0.09%013F-HRTimeline
Qube Research & Technologies Ltd273,444$2.47M<0.01%+126,83913F-HRTimeline
Moody Aldrich Partners LLC262,938$2.37M0.44%new13F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC251,994$2.28M0.06%-180,53313F-HRTimeline
Opaleye Management Inc.251,932$2.27M0.3%new13F-HR/ATimeline
ING GROEP NV239,000$2.16M0.01%new13F-HRTimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC233,600$2.11M0.04%013F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…227,229$2.05M<0.01%new13F-HRTimelineGroup
DIADEMA PARTNERS LP200,000$1.81M1.08%+128,79613F-HRTimeline
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.180,114$1.63M0.34%-260,00013F-HRTimelineGroup
GSA CAPITAL PARTNERS LLP172,363$1.56M0.13%-69,86613F-HRTimeline
Prospera Financial Services Inc151,570$1.37M0.02%+1,77013F-HRTimeline
CITIZENS FINANCIAL GROUP INC/RIin group CITIZENS FINANCIAL GROUP INC/…142,193$1.28M0.02%013F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP135,422$1.22M<0.01%+4,95013F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC118,702$1.07M<0.01%+116,87613F-HRTimelineGroup
Informed Momentum Co LLC111,398$1.01M0.11%new13F-HRTimeline
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…102,357$924K0.01%new13F-HRTimelineGroup
Birchview Capital, LP100,827$910K0.53%+2,00013F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC99,559$899K<0.01%+83,17513F-HRTimelineGroup
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC99,499$898K<0.01%+30,08613F-HRTimelineGroup
SECTORAL ASSET MANAGEMENT INC96,945$875K0.7%-1,010,32213F-HRTimeline
HighTower Advisors, LLC85,972$776K<0.01%-25,26913F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC81,600$737K0.06%013F-HR/ATimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO78,703$711K<0.01%new13F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC76,200$688K0.01%new13F-HRTimelineGroup
UBS Group AGin group UBS Group AG68,216$616K<0.01%-459,07613F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd67,361$608K0.02%-135,02113F-HRTimelineGroup
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.in group LANDSCAPE CAPITAL MANAGEMENT,…57,437$519K0.03%new13F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC56,344$509K<0.01%+53,87113F-HRTimelineGroup
Persistent Asset Partners Ltd53,642$484K0.23%+37,34713F-HRTimeline
ExodusPoint Capital Management, LP50,009$452K0.01%new13F-HRTimeline
Ashton Thomas Private Wealth, LLC48,316$436K0.01%+14,94213F-HRTimeline
LPL Financial LLC46,005$415K<0.01%013F-HRTimeline
GLENMEDE TRUST CO NAin group GLENMEDE TRUST CO NA42,055$380K<0.01%13F-HRTimelineGroup
Lion Point Capital, LP41,500$375K1.94%new13F-HRTimeline
Schonfeld Strategic Advisors LLC40,027$361K<0.01%-174,16213F-HRTimeline
Velan Capital Investment Management LP40,000$361K0.21%013F-HRTimeline
BROWN ADVISORY INCin group BROWN ADVISORY INC37,160$336K<0.01%013F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/33,977$307K<0.01%-35,10013F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC32,630$295K<0.01%-2,33013F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…32,483$293K0.08%new13F-HRTimelineGroup
Graham Capital Management, L.P.32,381$292K0.01%-126,68213F-HRTimeline
FOX RUN MANAGEMENT, L.L.C.32,361$292K0.05%new13F-HRTimeline
Quadrature Capital Ltdin group Quadrature Capital Ltd31,501$284K<0.01%new13F-HRTimelineGroup
Cannell & Spears LLC31,000$280K0.01%+2,00013F-HRTimeline
Man Group plcin group Man Group plc28,621$258K<0.01%-51,94813F-HRTimelineGroup
Arrowpoint Investment Partners (Singapo…in group Arrowpoint Investment Partner…28,453$257K0.04%+1,59513F-HRTimelineGroup
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC28,229$255K<0.01%new13F-HRTimelineGroup
OMERS ADMINISTRATION Corp26,200$237K<0.01%new13F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC25,768$233K<0.01%-157,67313F-HRTimelineGroup
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.23,750$214K<0.01%-10,35013F-HRTimelineGroup
ALGERT GLOBAL LLC23,050$208K<0.01%-20,27013F-HR/ATimeline
China Universal Asset Management Co., L…21,628$195K0.01%new13F-HRTimeline
BANK OF NOVA SCOTIAin group BANK OF NOVA SCOTIA19,534$176K<0.01%new13F-HRTimelineGroup
EntryPoint Capital, LLC17,708$160K0.06%new13F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC17,475$158K<0.01%new13F-HRTimelineGroup
J. Goldman & Co LP17,406$157K0.01%new13F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp14,638$132K<0.01%new13F-HRTimelineGroup
PROFUND ADVISORS LLC14,560$131K<0.01%new13F-HRTimeline
Rafferty Asset Management, LLC13,638$123K<0.01%new13F-HRTimeline
Scientech Research LLC13,174$119K0.07%new13F-HRTimeline
Lighthouse Investment Partners, LLCin group Lighthouse Investment Partner…12,660$114K<0.01%new13F-HRTimelineGroup
Entropy Technologies, LP11,663$105K0.01%new13F-HRTimeline
FMR LLCin group FMR LLC11,422$103K<0.01%-1,58013F-HRTimelineGroup
Avestar Capital, LLC11,412$103K0.01%013F-HRTimeline
Orion Porfolio Solutions, LLC11,355$103K<0.01%new13F-HRTimeline
Walleye Capital LLCgroup of 2 filers holding11,306$102K-174,159Timeline
State of Wyoming11,240$101K0.01%new13F-HRTimeline
IEQ CAPITAL, LLC10,102$91.2K<0.01%-59,80913F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\5,790$52.3K<0.01%new13F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO5,449$49.2K<0.01%-742,63913F-HRTimelineGroup
CANADA PENSION PLAN INVESTMENT BOARD5,100$46.1K<0.01%new13F-HRTimeline
CWM, LLCin group CWM, LLC4,425$40K<0.01%-14,85413F-HRTimelineGroup
Asset Dedication, LLC4,301$38.8K<0.01%013F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…4,080$36.8K<0.01%013F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…3,468$31.3K<0.01%new13F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…3,449$31.1K<0.01%-3,39313F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…2,543$23K<0.01%-46213F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.1,402$12.7K<0.01%new13F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN1,100$9.93K<0.01%+1,00013F-HRTimelineGroup
Physician Wealth Advisors, Inc.833$7.52K<0.01%013F-HRTimeline
Fortitude Family Office, LLC830$7.5K<0.01%013F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.806$7.28K<0.01%013F-HRTimelineGroup
QUADRANT CAPITAL GROUP LLC794$7.17K<0.01%new13F-HRTimeline
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.748$6.75K<0.01%-3,94813F-HRTimelineGroup
Clearstead Advisors, LLC500$4.51K<0.01%013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC481$4.34K<0.01%013F-HRTimeline
Basecamp Wealth Advisors LLC362$3.27K<0.01%13F-HRTimeline
MassMutual Private Wealth & Trust, FSB360$3.25K<0.01%new13F-HRTimeline
Rialto Wealth Management, LLC296$2.67K<0.01%013F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.238$2K<0.01%new13F-HRTimelineGroup
True Wealth Design, LLC165$1.49K<0.01%-1,54713F-HRTimeline
Modus Advisors, LLC150$1.35K<0.01%new13F-HRTimeline
OPTIMA CAPITAL LLC142$1.28K<0.01%new13F-HRTimeline
SIGNATUREFD, LLC129$1.17K<0.01%new13F-HRTimeline
SBI Securities Co., Ltd.125$1.13K<0.01%-213F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA91$1K<0.01%-44413F-HRTimelineGroup
Allworth Financial LP86$777<0.01%-10913F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…40$361<0.01%-9013F-HRTimelineGroup
Arax Advisory Partners15$135<0.01%-7,18813F-HRTimeline
Dauntless Investment Group, LLC1$9<0.01%new13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.