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Disclosery

FULC FULCRUM THERAPEUTICS INC

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COMMON STOCK (common), issuer CIK 1680581

169 managers (172 13F filers) reported a position in FULC shares at 2025-12-31, 67,444,383 shares in all. 56 filers opened a position and 16 filers sold out during the quarter.

Managers
169
13F filers
172
New
56
Added
43
Reduced
49
Sold out
16
Shares held by filers
67,444,383

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
MONTANOVA CAPITAL, LLC6,561,111$74.2M1.85%+1,180,11113F-HRTimeline
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.6,053,960$68.5M0.7%-4,175,13913F-HRTimelineGroup
TCG Crossover Management, LLC5,250,000$59.4M1.97%013F-HRTimeline
Nantahala Capital Management, LLCin group Nantahala Capital Management,…4,293,346$48.6M2.89%-377,43813F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.4,263,761$48.2M<0.01%+557,01113F-HRTimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding3,572,710$40.4M+560,078Timeline
BRAIDWELL LP3,061,222$34.6M1.11%+2,841,73413F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.2,398,232$27.1M0.04%new13F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.1,950,000$22.1M0.66%new13F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.1,913,755$21.6M0.02%+464,33213F-HRTimelineGroup
First Turn Management, LLC1,892,683$21.4M2.45%new13F-HRTimeline
GSK plc1,785,714$20.2M2.53%13F-HRTimeline
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…1,700,000$19.2M0.03%-732,00013F-HRTimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC1,375,472$15.6M2.01%+86,24713F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc1,254,027$14.2M0.02%+1,116,06613F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC1,253,749$14.2M1.06%+912,13713F-HR/ATimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC1,207,004$13.7M0.01%+352,44813F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,105,813$12.5M<0.01%+101,76213F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP1,051,124$11.9M<0.01%-248,18413F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP1,005,345$11.4M<0.01%-57,86213F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management970,439$11M0.02%-480,04113F-HRTimelineGroup
Vestal Point Capital, LP950,000$10.7M0.39%new13F-HRTimeline
GREAT POINT PARTNERS LLC800,000$9.05M2.93%new13F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC736,740$8.33M0.01%+196,09913F-HRTimelineGroup
Connor, Clark & Lunn Investment Managem…582,377$6.59M0.02%+198,23913F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP552,220$6.25M<0.01%-16,10213F-HRTimelineGroup
BOOTHBAY FUND MANAGEMENT, LLC517,526$5.85M0.15%-160,88813F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC493,750$5.58M0.01%+172,23013F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.417,189$4.72M<0.01%+293,31713F-HRTimelineGroup
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…394,650$4.46M0.65%new13F-HRTimelineGroup
Qube Research & Technologies Ltd392,489$4.44M0.01%new13F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co388,896$4.4M<0.01%+55,41313F-HRTimelineGroup
Sio Capital Management, LLC382,000$4.32M0.72%new13F-HRTimeline
Trexquant Investment LP355,547$4.02M0.04%+334,53213F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC323,879$3.66M<0.01%-262,47213F-HR/ATimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\287,096$3.25M<0.01%+1,76713F-HRTimelineGroup
BESSEMER GROUP INCin group BESSEMER GROUP INC286,988$3.25M<0.01%013F-HRTimelineGroup
Driehaus Capital Management LLC243,388$2.75M0.02%new13F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/231,177$2.61M<0.01%+83,96613F-HRTimelineGroup
Catalio Capital Management, LP201,301$2.28M0.4%new13F-HR/ATimeline
Nicholas Investment Partners, LP182,961$2.07M0.15%new13F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN166,395$1.88M<0.01%+133,88813F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY165,623$1.87M<0.01%-78,21213F-HR/ATimelineGroup
Simplify Asset Management Inc.159,674$1.81M0.03%+76,44013F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC157,672$1.78M<0.01%+5,42813F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…146,427$1.66M<0.01%-32,93113F-HRTimelineGroup
SummitTX Capital, L.P.138,143$1.56M0.05%new13F-HRTimeline
Fiduciary Trust Coin group Fiduciary Trust Co136,555$1.54M0.02%013F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC132,541$1.5M<0.01%+42,92513F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp116,906$1.32M<0.01%-2,25213F-HRTimelineGroup
Nuveen, LLCin group TIAA112,203$1.27M<0.01%013F-HRTimelineGroup
Walleye Capital LLCin group Walleye Capital LLC108,434$1.23M0.01%new13F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding103,676$1.17M-197,481Timeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP102,921$1.16M<0.01%new13F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC100,675$1.14M<0.01%-23,99113F-HRTimelineGroup
Maven Securities LTDin group Maven Securities LTD100,000$1.13M0.14%new13F-HRTimelineGroup
GSA CAPITAL PARTNERS LLP99,709$1.13M0.1%-16,35913F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC97,688$1.1M<0.01%+31,13813F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC92,200$1.04M0.01%new13F-HRTimelineGroup
Exome Asset Management LLC92,055$1.04M0.51%-6,74413F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding87,930$994K-77,223Timeline
STATE OF WISCONSIN INVESTMENT BOARD86,499$978K<0.01%+72,83313F-HRTimeline
RBF Capital, LLC80,506$911K0.04%013F-HR/ATimeline
Verition Fund Management LLC74,691$845K<0.01%new13F-HRTimeline
SUPERSTRING CAPITAL MANAGEMENT LP72,060$815K0.44%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC67,102$759K<0.01%+66,38413F-HRTimelineGroup
Y-Intercept (Hong Kong) Ltd66,716$755K0.02%+55,44413F-HRTimeline
Legato Capital Management LLC66,347$750K0.06%new13F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC65,852$745K<0.01%+48,02613F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/63,760$722K<0.01%-2,13213F-HRTimeline
Integrated Quantitative Investments LLC62,522$707K0.15%new13F-HRTimeline
Informed Momentum Co LLC61,620$697K0.08%new13F-HRTimeline
Atom Investors LP60,595$685K0.05%new13F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND57,725$653K<0.01%+44,62513F-HRTimeline
RHUMBLINE ADVISERS55,713$630K<0.01%-13,65913F-HRTimeline
DekaBank Deutsche Girozentrale60,000$617K<0.01%013F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC54,431$616K<0.01%-96,43613F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd51,802$586K0.02%new13F-HRTimelineGroup
KVP Capital Advisors, LP50,000$566K0.58%13F-HRTimeline
Burkehill Global Management, LP50,000$566K0.04%new13F-HRTimeline
SEVEN GRAND MANAGERS, LLC50,000$566K0.04%new13F-HRTimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…48,900$559K0.01%+33,59713F-HRTimelineGroup
STRS OHIO49,300$558K<0.01%-28,60013F-HRTimeline
Graham Capital Management, L.P.48,464$548K0.02%+17,97813F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources44,249$500K<0.01%-15,77313F-HRTimelineGroup
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC43,262$498K<0.01%-10,54413F-HR/ATimelineGroup
Jain Global LLC41,260$467K<0.01%new13F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC40,000$452K<0.01%-43,42813F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO37,511$424K<0.01%new13F-HRTimelineGroup
Campbell & CO Investment Adviser LLC35,601$403K0.02%-66,86913F-HRTimeline
GROUP ONE TRADING LLC34,750$393K0.01%+28,99013F-HRTimeline
AXQ CAPITAL, LP31,545$357K0.08%new13F-HRTimeline
Woodline Partners LP30,793$348K<0.01%new13F-HRTimeline
TWO SIGMA ADVISERS, LPin group TWO SIGMA INVESTMENTS, LP30,500$345K<0.01%-1,00013F-HRTimelineGroup
COUNTRY TRUST BANK30,041$340K0.01%013F-HRTimeline
LMR Partners LLPin group LMR Partners LLP30,000$339K<0.01%013F-HRTimelineGroup
Quantinno Capital Management LP29,264$331K<0.01%+4,61513F-HRTimeline
PRELUDE CAPITAL MANAGEMENT, LLC28,832$326K0.02%013F-HRTimeline
FOX RUN MANAGEMENT, L.L.C.25,568$289K0.04%-25,22313F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…22,714$257K<0.01%-3,18113F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding22,652$256K+2,646Timeline
Creative Planningin group Creative Planning22,104$250K<0.01%+7,75013F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO20,789$235K<0.01%+2,72013F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…20,463$231K0.06%new13F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC19,747$223K<0.01%+2,50313F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC17,400$197K<0.01%-230,80013F-HRTimeline
Quarry LP17,165$194K0.03%+13,39113F-HRTimeline
Schonfeld Strategic Advisors LLC16,791$190K<0.01%-349,51213F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc16,373$185K<0.01%013F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC15,502$175K<0.01%new13F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.15,270$173K<0.01%-59,32013F-HRTimeline
Man Group plcin group Man Group plc15,253$173K<0.01%new13F-HRTimelineGroup
EntryPoint Capital, LLC15,076$171K0.07%new13F-HRTimeline
WINTON GROUP Ltdin group WINTON GROUP Ltd14,294$162K0.01%-1,91813F-HRTimelineGroup
Alphabet Inc.in group Alphabet Inc.14,262$161K0.01%013F-HRTimelineGroup
Matisse Capital13,460$152K0.07%-5,17013F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …12,883$146K<0.01%-1,06513F-HRTimelineGroup
Police & Firemen's Retirement System of…12,843$145K<0.01%013F-HRTimeline
Entropy Technologies, LP11,996$136K0.01%new13F-HRTimeline
BAILARD, INC.11,781$133K<0.01%-15,10013F-HRTimeline
SG Americas Securities, LLC11,766$133K<0.01%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS10,522$119K<0.01%-3,75213F-HRTimelineGroup
ProShare Advisors LLC10,259$116K<0.01%new13F-HRTimeline
AlphaQuest LLC9,658$109K0.01%-25,71713F-HRTimeline
China Universal Asset Management Co., L…8,819$99.7K0.01%new13F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC8,184$92.6K<0.01%-1,42713F-HRTimelineGroup
SIMPLEX TRADING, LLC8,014$90.6K<0.01%-4,78613F-HRTimeline
FMR LLCin group FMR LLC7,691$87K<0.01%+34113F-HRTimelineGroup
Persistent Asset Partners Ltd6,615$74.8K0.04%new13F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA4,107$47K<0.01%-996,74213F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC3,602$40.7K<0.01%-67913F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…3,598$40.7K<0.01%013F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…3,574$40.4K<0.01%-10,15713F-HRTimelineGroup
MEEDER ASSET MANAGEMENT INCin group Meeder Advisory Services, Inc.3,479$39.3K<0.01%new13F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…2,651$30K<0.01%-68313F-HRTimeline
Sterling Capital Management LLC2,332$26.4K<0.01%-41413F-HRTimeline
Farther Finance Advisors, LLC2,190$24.8K<0.01%-4,92213F-HRTimeline
Versant Capital Management, Inc1,800$20.4K<0.01%013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,624$18.4K<0.01%-28613F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…1,442$16.3K<0.01%+2513F-HRTimelineGroup
AMALGAMATED BANK1,353$15K<0.01%-79413F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,062$12K<0.01%new13F-HRTimeline
IFP Advisors, Inc988$11.2K<0.01%-98813F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC915$7.87K<0.01%new13F-HRTimeline
Aster Capital Management (DIFC) Ltd623$7.05K<0.01%new13F-HRTimeline
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…472$5.34K<0.01%new13F-HR/ATimelineGroup
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/443$5K<0.01%+1513F-HRTimelineGroup
CWM, LLCin group CWM, LLC372$4K<0.01%+17313F-HRTimelineGroup
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.328$3.71K<0.01%013F-HRTimelineGroup
Optiver Holding B.V.in group Optiver Holding B.V.322$3.64K<0.01%013F-HRTimelineGroup
COMERICA BANK287$3.25K<0.01%new13F-HRTimeline
Physician Wealth Advisors, Inc.283$3.2K<0.01%013F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…224$2.53K<0.01%new13F-HR/ATimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…207$2.34K<0.01%+313F-HRTimelineGroup
Arax Advisory Partners181$2.05K<0.01%new13F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.180$2K<0.01%new13F-HRTimelineGroup
Rialto Wealth Management, LLC159$1.8K<0.01%013F-HRTimeline
Altshuler Shaham Ltd100$1.13K<0.01%new13F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.90$1.02K<0.01%013F-HRTimelineGroup
SIGNATUREFD, LLC68$769<0.01%new13F-HRTimeline
Caitong International Asset Management …41$464<0.01%new13F-HR/ATimeline
GAMMA Investing LLC25$283<0.01%new13F-HRTimeline
Keating Financial Advisory Services, In…24$271<0.01%13F-HRTimeline
True Wealth Design, LLC16$181<0.01%013F-HRTimeline
MAI Capital Management10$114<0.01%new13F-HRTimeline
ROTHSCHILD INVESTMENT LLC8$90<0.01%new13F-HRTimeline
SBI Securities Co., Ltd.4$45<0.01%-2413F-HRTimeline
SJS Investment Consulting Inc.3$34<0.01%new13F-HRTimeline
Essential Partners LLC1$11<0.01%013F-HRTimeline