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Disclosery

FULC FULCRUM THERAPEUTICS INC

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COMMON STOCK (common), issuer CIK 1680581

127 managers (129 13F filers) reported a position in FULC shares at 2025-09-30, 53,791,125 shares in all. 26 filers opened a position and 18 filers sold out during the quarter.

Managers
127
13F filers
129
New
26
Added
40
Reduced
43
Sold out
18
Shares held by filers
53,791,125

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.10,229,099$94.1M1.16%013F-HRTimelineGroup
MONTANOVA CAPITAL, LLC5,381,000$49.5M1.5%+298,10013F-HRTimeline
TCG Crossover Management, LLC5,250,000$48.3M2.38%013F-HRTimeline
Nantahala Capital Management, LLCin group Nantahala Capital Management,…4,670,784$43M2.65%+382,48513F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.3,706,750$34.1M<0.01%-672,27313F-HRTimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding3,012,632$27.7M-146,754Timeline
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…2,432,000$22.4M0.04%-2,157,00013F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management1,450,480$13.3M0.03%+112,26613F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.1,449,423$13.3M0.01%+272,71213F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP1,299,308$12M<0.01%-73,32913F-HRTimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC1,289,225$11.9M2.4%+860,70413F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP1,063,207$9.78M<0.01%-155,15913F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,004,051$9.24M<0.01%-189,08713F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA1,000,849$9.21M<0.01%+996,63213F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC854,556$7.86M0.01%+688,32213F-HRTimelineGroup
BOOTHBAY FUND MANAGEMENT, LLC678,414$6.24M0.16%+537,03613F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC586,351$5.39M<0.01%-557,18513F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP568,322$5.23M<0.01%-43,21413F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC540,641$4.97M0.01%-22,73913F-HRTimelineGroup
Connor, Clark & Lunn Investment Managem…384,138$3.53M0.01%+41,59113F-HRTimeline
Schonfeld Strategic Advisors LLC366,303$3.37M0.02%+161,90313F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC341,612$3.14M0.31%+288,26313F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co333,483$3.07M<0.01%-54,29913F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC321,520$2.96M<0.01%+304,09313F-HRTimelineGroup
UBS Group AGin group UBS Group AG301,157$2.77M<0.01%+165,95213F-HRTimelineGroup
BESSEMER GROUP INCin group BESSEMER GROUP INC286,988$2.64M<0.01%013F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\285,329$2.63M<0.01%+6,07813F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC248,200$2.28M<0.01%+169,70013F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY243,835$2.24M<0.01%-70,57513F-HR/ATimelineGroup
BRAIDWELL LP219,488$2.02M0.06%new13F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…179,358$1.65M<0.01%+52,95613F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding165,153$1.52M-45,919Timeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC152,244$1.4M<0.01%+19,89513F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC150,867$1.39M<0.01%+45,17413F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/147,211$1.35M<0.01%+101,22213F-HR/ATimelineGroup
Aberdeen Group plcin group Aberdeen Group plc137,961$1.27M<0.01%+79,26513F-HRTimelineGroup
Fiduciary Trust Coin group Fiduciary Trust Co136,555$1.26M0.01%013F-HRTimelineGroup
J. Goldman & Co LP135,000$1.24M0.05%+67,50013F-HRTimeline
HRT FINANCIAL LP124,924$1.15M<0.01%new13F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC124,666$1.15M<0.01%new13F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.123,872$1.14M<0.01%-346,46113F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp119,158$1.1M<0.01%-17,84213F-HRTimelineGroup
GSA CAPITAL PARTNERS LLP116,068$1.07M0.09%+83,50513F-HRTimeline
Nuveen, LLCin group TIAA112,203$1.03M<0.01%-12,52013F-HRTimelineGroup
Campbell & CO Investment Adviser LLC102,470$943K0.07%new13F-HRTimeline
Exome Asset Management LLC98,799$909K0.6%-346,15013F-HRTimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC95,400$878K0.02%-2,20013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC89,616$824K<0.01%-22,44713F-HR/ATimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC83,428$768K<0.01%013F-HRTimeline
Simplify Asset Management Inc.83,234$766K0.02%+10,08013F-HRTimeline
RBF Capital, LLC80,506$741K0.03%013F-HRTimeline
STRS OHIO77,900$717K<0.01%+2,80013F-HRTimeline
ALLIANCEBERNSTEIN L.P.74,590$686K<0.01%013F-HRTimeline
JACOBS LEVY EQUITY MANAGEMENT, INC70,015$644K<0.01%-22,45513F-HRTimeline
RHUMBLINE ADVISERS69,372$638K<0.01%-13,87813F-HRTimeline
SUMMIT WEALTH GROUP LLC / CO533$616K0.07%new13F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC66,550$612K<0.01%new13F-HRTimelineGroup
DekaBank Deutsche Girozentrale60,000$611K<0.01%013F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/65,892$607K<0.01%-3,13613F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources60,022$552K<0.01%013F-HRTimelineGroup
ACUTA CAPITAL PARTNERS, LLC57,141$526K0.54%-2,50913F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC53,806$474K<0.01%+4,27013F-HRTimelineGroup
FOX RUN MANAGEMENT, L.L.C.50,791$467K0.07%new13F-HRTimeline
AlphaQuest LLC35,375$325K0.02%new13F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN32,507$299K<0.01%-1,24113F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding31,500$290K-109,565Timeline
Graham Capital Management, L.P.30,486$280K0.01%+18,43413F-HRTimeline
COUNTRY TRUST BANK30,041$276K0.01%-14513F-HRTimeline
LMR Partners LLPin group LMR Partners LLP30,000$276K<0.01%-20,00013F-HRTimelineGroup
PRELUDE CAPITAL MANAGEMENT, LLC28,832$265K0.02%-114,29713F-HRTimeline
BAILARD, INC.26,881$247K0.01%013F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…25,895$238K<0.01%-6,65013F-HRTimelineGroup
Quantinno Capital Management LP24,649$227K<0.01%new13F-HRTimeline
PharVision Advisers, LLC23,868$220K0.12%new13F-HRTimeline
Trexquant Investment LP21,015$193K<0.01%new13F-HRTimeline
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.in group Mirae Asset Global Investment…20,006$184K<0.01%-9,42713F-HRTimelineGroup
Matisse Capital18,630$171K0.08%-7,47013F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO18,069$166K<0.01%-8,09313F-HR/ATimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC17,826$164K<0.01%+4,15113F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC17,244$159K<0.01%-10,81413F-HRTimeline
ALGERT GLOBAL LLC16,550$152K<0.01%new13F-HR/ATimeline
Legal & General Group Plcin group Legal & General Group Plc16,373$151K<0.01%-1,08813F-HRTimelineGroup
WINTON GROUP Ltdin group WINTON GROUP Ltd16,212$149K0.01%new13F-HRTimelineGroup
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…15,303$141K<0.01%new13F-HRTimelineGroup
Creative Planningin group Creative Planning14,354$132K<0.01%-2,58513F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS14,274$131K<0.01%+8,27513F-HRTimelineGroup
Alphabet Inc.in group Alphabet Inc.14,262$131K0.01%013F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …13,948$128K<0.01%-5,93913F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…13,731$126K<0.01%+4,42313F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD13,666$126K<0.01%new13F-HRTimeline
Sanctuary Advisors, LLC13,154$121K<0.01%new13F-HR/ATimeline
NEW YORK STATE COMMON RETIREMENT FUND13,100$121K<0.01%013F-HRTimeline
Police & Firemen's Retirement System of…12,843$118K<0.01%+36813F-HRTimeline
SIMPLEX TRADING, LLC12,800$117K<0.01%-96,56513F-HRTimeline
Y-Intercept (Hong Kong) Ltd11,272$104K<0.01%new13F-HRTimeline
MARTINGALE ASSET MANAGEMENT L P10,563$97.2K<0.01%-80,45213F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC9,611$88.4K<0.01%new13F-HRTimelineGroup
FMR LLCin group FMR LLC7,350$67.6K<0.01%+38313F-HRTimelineGroup
Farther Finance Advisors, LLC7,112$65.4K<0.01%+3,69713F-HRTimeline
BIT Capital GmbH6,090$56K<0.01%+1,25813F-HRTimeline
GROUP ONE TRADING LLC5,760$53K<0.01%+14113F-HRTimeline
NISA INVESTMENT ADVISORS, LLC4,281$39.4K<0.01%013F-HRTimeline
Quarry LP3,774$34.7K0.01%new13F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…3,598$33.1K<0.01%-2,48113F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…3,334$30.7K<0.01%+213F-HRTimeline
SUMMIT SECURITIES GROUP LLC2,917$26.8K0.01%new13F-HRTimeline
Sterling Capital Management LLC2,746$25.3K<0.01%+1,40713F-HRTimeline
MACQUARIE GROUP LTDin group MACQUARIE GROUP LTD2,495$23K<0.01%new13F-HRTimelineGroup
AMALGAMATED BANK2,147$20K<0.01%013F-HRTimeline
IFP Advisors, Inc1,976$18.2K<0.01%+36813F-HR/ATimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,910$17.6K<0.01%-4,46713F-HRTimelineGroup
Versant Capital Management, Inc1,800$16.6K<0.01%new13F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…1,417$13K<0.01%-3213F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC718$6.61K<0.01%-20,29813F-HRTimelineGroup
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/428$3.94K<0.01%-4513F-HRTimelineGroup
Rise Advisors, LLC348$3.2K<0.01%013F-HRTimeline
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.328$3.02K<0.01%new13F-HRTimelineGroup
Optiver Holding B.V.in group Optiver Holding B.V.322$2.96K<0.01%new13F-HRTimelineGroup
Physician Wealth Advisors, Inc.283$2.6K<0.01%013F-HRTimeline
CWM, LLCin group CWM, LLC199$2K<0.01%+1413F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…204$1.88K<0.01%-1413F-HRTimelineGroup
Rialto Wealth Management, LLC159$1.46K<0.01%013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.90$828<0.01%013F-HRTimelineGroup
SBI Securities Co., Ltd.28$258<0.01%+213F-HRTimeline
True Wealth Design, LLC16$148<0.01%013F-HRTimeline
Clearstead Advisors, LLC4$37<0.01%new13F-HRTimeline
Essential Partners LLC1$9<0.01%new13F-HRTimeline