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Disclosery

13F-HR filed by Exome Asset Management LLC

Exome Asset Management LLC filed this 13F-HR for the quarter ended 2025-12-31, filed 2026-02-13, with 60 holding rows worth $209,146,246.

Accession
0001420506-26-000376
Filer
CIK 2011932
Filed
2026-02-13
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q4 2025

A holdings report, 60 entries on the cover page, a total value of $209,146,246 stated on the cover page (in dollars after the unit check, H1), rows summing to $209,146,246 with VALUE read as dollars as filed, 13F file number 028-23951. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
PRAXIS PRECISION MEDICINES I74006W207COM NEW58,122$17,130,878dollars as filed
COGENT BIOSCIENCES INC19240Q201COM305,568$10,853,775dollars as filed
GUARDANT HEALTH INC COM40131M109Stock98,182$10,028,309dollars as filed
IONIS PHARMACEUTICALS INC COM462222100Stock116,515$9,217,502dollars as filed
Eli Lilly and Company532457108COM7,852$8,438,387dollars as filed
CYTOKINETICS INC23282W605COM NEW124,749$7,926,551dollars as filed
WAVE LIFE SCIENCES LTD SHSY95308105Stock421,488$7,165,296dollars as filed
VERA THERAPEUTICS INC92337R101COMMON STOCK124,391$6,299,160dollars as filed
BRIDGEBIO PHARMA INC10806X102COM80,723$6,174,502dollars as filed
Elevance Health, Inc.036752103COM17,191$6,026,305dollars as filed
ASTRAZENECA PLC SPONSORED ADR046353108ADR28,362$5,260,652dollars as filed
JAZZ PHARMACEUTICALS PLC SHS USDG50871105Stock26,494$4,503,980dollars as filed
NATERA INC COM632307104Stock18,650$4,272,529dollars as filed
IMMUNOVANT INC45258J102COM158,622$4,032,171dollars as filed
UNIVERSAL HLTH SVCS INC CL B913903100Stock17,628$3,843,257dollars as filed
UNITED THERAPEUTICS CORP DEL COM91307C102Stock7,685$3,744,516dollars as filed
AGIOS PHARMACEUTICALS INC00847X104COM136,942$3,727,561dollars as filed
DISC MEDICINE INC COM254604101Stock46,743$3,711,862dollars as filed
Intuitive Surgical,Inc.46120E602COM6,358$3,600,917dollars as filed
GLAUKOS CORP COM377322102Stock31,471$3,553,391dollars as filed
ENLIVEN THERAPEUTICS INC COM29337E102Stock222,308$3,423,543dollars as filed
CELCUITY INC15102K100COM34,289$3,419,985dollars as filed
APELLIS PHARMACEUTICALS INC03753U106COM135,849$3,412,527dollars as filed
TRAVERE THERAPEUTICS INC89422G107COM89,052$3,402,677dollars as filed
DEXCOM INC COM252131107Stock50,147$3,328,256dollars as filed
ARROWHEAD PHARMACEUTICALS IN04280A100COM49,758$3,303,434dollars as filed
CYTOMX THERAPEUTICS INC23284F105COMMON STOCK745,305$3,174,999dollars as filed
LIQUIDIA CORPORATION COM NEW53635D202Stock91,148$3,143,695dollars as filed
VERASTEM INC92337C203COMMON STOCK401,743$3,101,456dollars as filed
TRAVERE THERAPEUTICS INC89422G957PUT74,700$2,854,287dollars as filedput
ALUMIS INC022307102COM292,250$2,852,360dollars as filed
PENUMBRA INC COM70975L107Stock9,000$2,798,190dollars as filed
10X GENOMICS INC CL A COM88025U109Stock163,658$2,669,262dollars as filed
IMMUNOCORE HLDGS PLC ADS45258D105ADR76,750$2,663,993dollars as filed
EDGEWISE THERAPEUTICS INC28036F105COM100,046$2,482,641dollars as filed
NEXTCURE INC65343E207COM NEW165,000$2,341,350dollars as filed
BELITE BIO INC07782B104CMN14,328$2,291,907dollars as filed
WAYSTAR HLDG CORP946784105COM68,969$2,258,735dollars as filed
IRONWOOD PHARMACEUTICALS INC46333X108COMMON STOCK648,532$2,185,553dollars as filed
KARYOPHARM THERAPEUTICS INC48576U205COMMON STOCK295,541$2,175,182dollars as filed
ADAGENE INC005329107CMN1,060,221$2,003,818dollars as filed
NOVABRIDGE BIOSCIENCES44975P103CMN499,587$1,988,356dollars as filed
UnitedHealth Group Inc91324P102COM5,835$1,926,192dollars as filed
PALISADE BIO INC696389402COMMON STOCK758,203$1,781,777dollars as filed
UPSTREAM BIO INC91678A107COMMON STOCK64,845$1,760,542dollars as filed
GOSSAMER BIO INC COM38341P102Stock451,699$1,400,267dollars as filed
DISC MEDICINE INC254604951PUT16,000$1,270,560dollars as filedput
INHIBIKASE THERAPEUTICS INC45719W205COMMON STOCK600,000$1,230,000dollars as filed
IQVIA HLDGS INC COM46266C105Stock5,378$1,212,255dollars as filed
TENET HEALTHCARE CORP COM NEW88033G407Stock6,084$1,209,012dollars as filed
CORBUS PHARMACEUTICALS21833P301COM NEW139,543$1,135,880dollars as filed
FULCRUM THERAPEUTICS INC359616109COMMON STOCK92,055$1,041,142dollars as filed
ESTABLISHMENT LABS HOLDINGSG31249108COMMON STOCK13,100$954,728dollars as filed
ULTRAGENYX PHARMACEUTICAL IN90400D958COM35,200$809,600dollars as filedcall
ALUMIS INC022307952COM53,200$519,232dollars as filedput
ALDEYRA THERAPEUTICS INC01438T906COM100,000$518,000dollars as filedcall
RAPT THERAPEUTICS INC75382E208COM NEW14,194$480,751dollars as filed
PRECIGEN INC74017N955COM100,000$418,000dollars as filedput
Arbutus Biopharma Corp03879J100Common Shares, without par value75,484$363,078dollars as filed
SOLENO THERAPEUTICS INC834203959PUT7,100$327,523dollars as filedput

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001420506-26-000376this filing2026-02-13acceptance time not in the bulk data set