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Disclosery

AMLX AMYLYX PHARMACEUTICALS INC

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COM (common), issuer CIK 1658551

120 managers (123 13F filers) reported a position in AMLX shares at 2024-12-31, 49,804,272 shares in all. 27 filers opened a position and 20 filers sold out during the quarter.

Managers
120
13F filers
123
New
27
Added
35
Reduced
40
Sold out
20
Shares held by filers
49,804,272

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

The latest Form 4 transactions, non-derivative.
OwnerDateSharesPriceFiling
MILNE GEORGE M JRdirector2026-10-05-30,000 S$27.6968Form 4

13F holders, Q4 2024

Filers in the available 13F reports with a share position at 2024-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC6,774,348$25.6M0.71%+4,648,69913F-HRTimelineGroup
TCG Crossover Management, LLC4,643,812$17.6M1.72%013F-HRTimeline
VANGUARD GROUP INCgroup of 2 filers holding2,710,213$10.2M-396,024Timeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/2,426,263$9.17M<0.01%+1,513,74813F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.2,278,934$8.61M<0.01%-269,27213F-HRTimelineGroup
Almitas Capital LLC2,032,370$7.68M1.69%+43,80713F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC1,970,704$7.45M0.01%+71,14413F-HRTimelineGroup
683 Capital Management, LLCin group 683 Capital Management, LLC1,930,000$7.3M0.72%-70,00013F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC1,859,896$7.03M<0.01%+246,03313F-HRTimelineGroup
Boxer Capital Management, LLCin group Boxer Capital Management, LLC1,750,000$6.62M0.56%13F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc1,722,805$6.51M0.01%-249,43713F-HRTimelineGroup
Nantahala Capital Management, LLCin group Nantahala Capital Management,…1,452,153$5.49M0.38%+47,58913F-HRTimelineGroup
Connor, Clark & Lunn Investment Managem…1,263,353$4.78M0.02%+382,60813F-HRTimeline
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding892,917$3.38M+216,180Timeline
Saturn V Capital Management LP889,073$3.36M1.32%new13F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…868,382$3.28M<0.01%+462,22513F-HRTimelineGroup
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.823,420$3.11M0.01%-1,200,00013F-HRTimelineGroup
Qube Research & Technologies Ltd780,566$2.95M<0.01%+596,67213F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC765,475$2.89M<0.01%+421,30213F-HRTimelineGroup
FMR LLCin group FMR LLC731,356$2.76M<0.01%+510,35513F-HRTimelineGroup
UBS Group AGin group UBS Group AG643,524$2.43M<0.01%+414,44813F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC611,926$2.31M0.01%-1,158,27113F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC609,324$2.3M<0.01%+34,31913F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC594,236$2.25M<0.01%+137,42013F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\570,857$2.16M<0.01%013F-HR/ATimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC567,903$2.15M<0.01%+16,86413F-HRTimelineGroup
Walleye Capital LLCgroup of 2 filers holding521,433$1.97M-149,161Timeline
Cubist Systematic Strategies, LLC472,397$1.79M0.03%+423,31613F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC464,400$1.76M<0.01%+192,60013F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY464,220$1.75M<0.01%-14,04513F-HR/ATimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC348,000$1.32M0.03%new13F-HRTimelineGroup
JACOBS LEVY EQUITY MANAGEMENT, INC314,939$1.19M<0.01%-163,50113F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.306,744$1.16M<0.01%-384,32213F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co298,949$1.13M<0.01%-3,32113F-HRTimelineGroup
Aldebaran Capital, LLC262,753$993K0.94%-7,05013F-HRTimeline
STATE STREET CORPin group STATE STREET CORP218,383$825K<0.01%+63,47513F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…209,708$793K<0.01%new13F-HRTimelineGroup
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.202,316$765K<0.01%+16,03013F-HRTimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC201,187$760K0.22%-73,36413F-HRTimelineGroup
Schonfeld Strategic Advisors LLC193,931$733K<0.01%+27,50213F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC188,386$712K<0.01%-460,69313F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP184,678$698K<0.01%-99,30813F-HRTimelineGroup
Alpha Wave Global, LP148,627$562K0.26%-520,86013F-HRTimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC146,500$554K0.01%+16,50013F-HRTimeline
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/143,512$542K<0.01%013F-HRTimelineGroup
Kennondale Capital Management LLC134,445$508K0.55%13F-HR/ATimeline
MACKENZIE FINANCIAL CORP111,310$421K<0.01%+78,07013F-HR/ATimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP106,564$403K<0.01%+11,21413F-HRTimelineGroup
ExodusPoint Capital Management, LP106,237$402K<0.01%new13F-HRTimeline
Jump Financial, LLCin group Jump Financial, LLC104,342$394K0.01%new13F-HRTimelineGroup
Man Group plcin group Man Group plc100,059$378K<0.01%-30,80313F-HRTimelineGroup
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC100,000$378K0.03%013F-HRTimelineGroup
Hennion & Walsh Asset Management, Inc.90,619$343K0.02%-23,91513F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC80,543$304K0.01%-4,93413F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC75,284$285K<0.01%+27,27913F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC74,845$283K<0.01%-9,72713F-HR/ATimelineGroup
Point72 Asia (Singapore) Pte. Ltd.72,863$275K0.07%-10,70013F-HRTimeline
OMERS ADMINISTRATION Corp66,000$249K<0.01%new13F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC59,310$224K<0.01%+38,26113F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/57,700$219K<0.01%+2,10013F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO55,606$210K<0.01%-84,95313F-HRTimelineGroup
ALPS ADVISORS INCin group ALPS ADVISORS INC55,430$210K<0.01%new13F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP54,114$205K<0.01%new13F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd53,376$202K0.02%+5,70413F-HRTimelineGroup
Mariner, LLCin group Mariner, LLC50,539$191K<0.01%-5,79513F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC50,428$191K<0.01%new13F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management50,248$190K<0.01%-65513F-HRTimelineGroup
GROUP ONE TRADING LLC49,899$189K0.01%-79,39113F-HR/ATimeline
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.in group LANDSCAPE CAPITAL MANAGEMENT,…49,661$188K0.02%new13F-HRTimelineGroup
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.46,200$175K<0.01%013F-HR/ATimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…45,987$174K<0.01%+36,34713F-HRTimelineGroup
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC35,868$136K<0.01%+20,47013F-HRTimelineGroup
Centiva Capital, LP33,831$128K<0.01%new13F-HRTimeline
TUDOR INVESTMENT CORP ET AL33,687$127K<0.01%new13F-HRTimeline
PARSONS CAPITAL MANAGEMENT INC/RI21,645$81.8K<0.01%-30013F-HRTimeline
Marex Group Ltdin group Marex Group Ltd20,000$75.6K<0.01%-20,00013F-HRTimelineGroup
BROWN ADVISORY INCin group BROWN ADVISORY INC19,930$75.3K<0.01%-2013F-HRTimelineGroup
WEDBUSH SECURITIES INC19,914$75K<0.01%new13F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC19,400$73.3K<0.01%013F-HRTimelineGroup
SIMPLEX TRADING, LLC17,819$67K<0.01%-93,90913F-HRTimeline
Engineers Gate Manager LP17,637$66.7K<0.01%new13F-HRTimeline
State of Wyoming16,077$60.8K0.01%-9,70013F-HRTimeline
SG Americas Securities, LLC15,958$60K<0.01%-41,42813F-HRTimeline
Y-Intercept (Hong Kong) Ltd14,809$56K<0.01%new13F-HRTimeline
China Universal Asset Management Co., L…14,535$54.9K0.01%+1,44113F-HRTimeline
EntryPoint Capital, LLC13,909$52.6K0.02%new13F-HRTimeline
RPO LLC12,136$45.9K0.06%new13F-HRTimeline
Alpine Global Management, LLC12,017$45.4K0.01%new13F-HR/ATimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA11,874$45K<0.01%+2413F-HRTimelineGroup
BANK OF NOVA SCOTIAin group BANK OF NOVA SCOTIA11,884$44.9K<0.01%+1,18813F-HR/ATimelineGroup
FOX RUN MANAGEMENT, L.L.C.11,788$44.6K0.01%new13F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC11,566$43.3K<0.01%-50,12113F-HRTimelineGroup
Vident Advisory, LLCin group Vident Advisory, LLC10,862$41.1K<0.01%-4,71013F-HRTimelineGroup
GSA CAPITAL PARTNERS LLP10,639$40K<0.01%new13F-HRTimeline
R Squared Ltd6,370$24.1K0.02%13F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…5,069$19.2K<0.01%-1,92013F-HRTimelineGroup
Point72 (DIFC) Ltd4,796$18.1K<0.01%new13F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\4,000$15.1K<0.01%new13F-HRTimelineGroup
Advisors Asset Management, Inc.3,902$14.8K<0.01%-3,75113F-HR/ATimeline
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…2,284$8.84K<0.01%-17813F-HRTimelineGroup
Arax Advisory Partners2,193$8.29K<0.01%013F-HRTimeline
Steward Partners Investment Advisory, L…2,000$7.56K<0.01%013F-HRTimeline
LORING WOLCOTT & COOLIDGE FIDUCIARY ADV…1,803$6.29K<0.01%013F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,439$5.44K<0.01%13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS1,149$4.34K<0.01%new13F-HRTimelineGroup
OLIVER LAGORE VANVALIN INVESTMENT GROUP1,100$4.16K<0.01%-50013F-HRTimeline
CWM, LLCin group CWM, LLC890$3K<0.01%013F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.638$2.41K<0.01%+42313F-HR/ATimelineGroup
Dunhill Financial, LLC600$2.27K<0.01%013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC495$1.87K<0.01%-25013F-HRTimeline
Global Retirement Partners, LLC400$1.51K<0.01%new13F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN300$1.13K<0.01%013F-HRTimelineGroup
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.266$1K<0.01%013F-HRTimelineGroup
HARBOUR INVESTMENTS, INC.90$340<0.01%new13F-HRTimeline
Catherine Avery Investment Management L…87$329<0.01%13F-HR/ATimeline
SALEM INVESTMENT COUNSELORS INC55$208<0.01%013F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…53$200<0.01%-4313F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…25$95<0.01%new13F-HRTimelineGroup
SBI Securities Co., Ltd.1$4<0.01%13F-HRTimeline
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$00%013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.

Events

  • MILNE GEORGE M JR sold 30,000 AMLX shares on 2026-10-05, Form 4 filed 2026-10-07. 0001193125-26-416950

    Accepted , ingested