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Disclosery

AMLX AMYLYX PHARMACEUTICALS INC

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COM (common), issuer CIK 1658551

135 managers (137 13F filers) reported a position in AMLX shares at 2025-03-31, 73,897,737 shares in all. 31 filers opened a position and 16 filers sold out during the quarter.

Managers
135
13F filers
137
New
31
Added
50
Reduced
31
Sold out
16
Shares held by filers
73,897,737

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

The latest Form 4 transactions, non-derivative.
OwnerDateSharesPriceFiling
MILNE GEORGE M JRdirector2026-10-05-30,000 S$27.6968Form 4

13F holders, Q1 2025

Filers in the available 13F reports with a share position at 2025-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC7,874,348$27.9M0.99%+1,100,00013F-HR/ATimelineGroup
TCG Crossover Management, LLC5,943,812$21M2.87%+1,300,00013F-HRTimeline
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…5,697,605$20.2M0.04%new13F-HRTimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding4,138,268$14.6M+1,428,055Timeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC3,081,853$10.9M0.01%+2,487,61713F-HRTimelineGroup
Nantahala Capital Management, LLCin group Nantahala Capital Management,…2,934,405$10.4M0.86%+1,482,25213F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC2,757,776$9.76M0.01%+787,07213F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc2,430,358$8.6M0.02%+707,55313F-HRTimelineGroup
Saturn V Capital Management LP2,426,436$8.59M4.33%+1,537,36313F-HRTimeline
683 Capital Management, LLCin group 683 Capital Management, LLC2,411,400$8.54M0.87%+481,40013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.2,387,409$8.45M<0.01%+108,47513F-HRTimelineGroup
Almitas Capital LLC2,122,597$7.51M2.49%+90,22713F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC2,002,961$7.09M<0.01%+143,06513F-HR/ATimelineGroup
GREAT POINT PARTNERS LLC1,811,996$6.41M3.49%new13F-HRTimeline
Boxer Capital Management, LLCin group Boxer Capital Management, LLC1,750,000$6.2M1.86%013F-HR/ATimelineGroup
Woodline Partners LP1,609,447$5.7M0.04%new13F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC1,471,587$5.21M1%new13F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…1,470,925$5.21M0.01%+602,54313F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding1,411,853$5M+518,936Timeline
UBS Group AGin group UBS Group AG1,388,427$4.92M<0.01%+744,90313F-HRTimelineGroup
Connor, Clark & Lunn Investment Managem…1,199,691$4.25M0.02%-63,66213F-HRTimeline
FMR LLCin group FMR LLC1,157,988$4.1M<0.01%+426,63213F-HRTimelineGroup
Qube Research & Technologies Ltd942,891$3.34M0.01%+162,32513F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.916,966$3.25M0.01%new13F-HR/ATimelineGroup
PFM Health Sciences, LP834,135$2.95M0.23%new13F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC806,161$2.85M<0.01%+238,25813F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/794,354$2.81M<0.01%-1,631,90913F-HRTimelineGroup
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.750,412$2.66M0.01%-73,00813F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\570,857$2.02M<0.01%013F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC515,100$1.82M<0.01%+50,70013F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY474,418$1.68M<0.01%+10,19813F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC463,240$1.64M<0.01%-146,08413F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co372,853$1.32M<0.01%+73,90413F-HR/ATimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC348,000$1.23M0.03%013F-HRTimelineGroup
Rock Springs Capital Management LP343,228$1.22M0.07%new13F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC331,185$1.17M<0.01%-434,29013F-HR/ATimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…290,682$1.03M<0.01%+80,97413F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.270,006$956K<0.01%-36,73813F-HRTimelineGroup
Allostery Investments LP266,099$942K1.36%new13F-HRTimeline
STATE STREET CORPin group STATE STREET CORP261,783$927K<0.01%+43,40013F-HRTimelineGroup
Aldebaran Capital, LLC259,253$918K0.87%-3,50013F-HRTimeline
Walleye Capital LLCgroup of 2 filers holding250,888$888K-270,545Timeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP247,275$875K<0.01%+62,59713F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC242,107$855K<0.01%-369,81913F-HRTimelineGroup
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.202,785$718K<0.01%+46913F-HRTimelineGroup
Kennondale Capital Management LLC202,743$718K0.78%+68,29813F-HRTimeline
Alpha Wave Global, LP187,311$663K0.3%+38,68413F-HRTimeline
OMERS ADMINISTRATION Corp169,600$600K0.01%+103,60013F-HRTimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC155,700$551K0.01%+9,20013F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management148,559$526K<0.01%+98,31113F-HRTimelineGroup
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/143,512$508K<0.01%013F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP139,332$493K<0.01%+32,76813F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC137,405$486K<0.01%+62,56013F-HR/ATimelineGroup
HRT FINANCIAL LP127,998$453K<0.01%new13F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP123,576$438K<0.01%+69,46213F-HRTimelineGroup
Schonfeld Strategic Advisors LLC117,140$415K<0.01%-76,79113F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC107,014$379K<0.01%+47,70413F-HRTimelineGroup
CANTOR FITZGERALD, L. P.in group CANTOR FITZGERALD, L. P.100,000$354K0.01%new13F-HRTimelineGroup
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC100,000$354K0.02%013F-HRTimelineGroup
Man Group plcin group Man Group plc87,352$309K<0.01%-12,70713F-HRTimelineGroup
Hennion & Walsh Asset Management, Inc.83,236$295K0.01%-7,38313F-HRTimeline
Cubist Systematic Strategies, LLC83,130$294K<0.01%-389,26713F-HRTimeline
JACOBS LEVY EQUITY MANAGEMENT, INC77,091$273K<0.01%-237,84813F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC75,849$269K<0.01%+56513F-HR/ATimelineGroup
Jain Global LLC73,942$262K0.01%new13F-HRTimeline
ALPS ADVISORS INCin group ALPS ADVISORS INC67,597$239K<0.01%+12,16713F-HRTimelineGroup
ExodusPoint Capital Management, LP59,491$211K<0.01%-46,74613F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/57,700$205K<0.01%013F-HRTimeline
ALGERT GLOBAL LLC57,133$202K0.01%new13F-HR/ATimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO54,069$191K<0.01%-1,53713F-HRTimelineGroup
Mariner, LLCin group Mariner, LLC50,906$180K<0.01%+36713F-HRTimelineGroup
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.46,200$164K<0.01%013F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.45,694$162K<0.01%new13F-HRTimelineGroup
GROUP ONE TRADING LLC43,234$153K0.01%-6,66513F-HRTimeline
LMR Partners LLPin group LMR Partners LLP43,228$153K<0.01%new13F-HRTimelineGroup
Point72 Asia (Singapore) Pte. Ltd.43,200$153K0.04%-29,66313F-HRTimeline
Quantessence Capital LLC40,134$142K0.04%new13F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd39,542$140K0.01%-13,83413F-HRTimelineGroup
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC37,796$134K<0.01%+1,92813F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL33,428$118K<0.01%-25913F-HRTimeline
Centiva Capital, LP28,222$99.9K0.01%-5,60913F-HRTimeline
Cannon Global Investment Management, LLC25,500$90.3K0.25%new13F-HRTimeline
SG Americas Securities, LLC25,210$89K<0.01%+9,25213F-HRTimeline
Verition Fund Management LLC24,013$85K<0.01%new13F-HRTimeline
GSA CAPITAL PARTNERS LLP23,085$82K0.01%+12,44613F-HRTimeline
Paloma Partners Management Coin group Paloma Partners Management Co22,242$78.7K0.01%new13F-HRTimelineGroup
PARSONS CAPITAL MANAGEMENT INC/RI21,645$76.6K<0.01%013F-HRTimeline
Premier Path Wealth Partners, LLC20,265$71.7K0.01%new13F-HRTimeline
Marex Group Ltdin group Marex Group Ltd20,000$70.8K<0.01%013F-HRTimelineGroup
BROWN ADVISORY INCin group BROWN ADVISORY INC19,930$70.6K<0.01%013F-HRTimelineGroup
China Universal Asset Management Co., L…17,188$60.8K0.01%+2,65313F-HRTimeline
CAPSTONE INVESTMENT ADVISORS, LLCin group CAPSTONE INVESTMENT ADVISORS,…16,150$57.2K<0.01%new13F-HRTimelineGroup
State of Wyoming15,920$56.4K0.01%-15713F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC15,200$53.8K<0.01%-4,20013F-HRTimelineGroup
Catalyst Funds Management Pty Ltd14,905$52.8K0.01%new13F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC14,419$51.4K<0.01%+2,85313F-HRTimelineGroup
Engineers Gate Manager LP13,382$47.4K<0.01%-4,25513F-HRTimeline
TWO SIGMA SECURITIES, LLC13,301$47.1K0.01%new13F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC12,805$45.3K<0.01%-37,62313F-HRTimelineGroup
R Squared Ltd12,736$45.1K0.05%+6,36613F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
Quadrature Capital Ltdin group Quadrature Capital Ltd12,744$45K<0.01%new13F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA11,850$42K<0.01%-2413F-HR/ATimelineGroup
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…11,330$40.1K<0.01%new13F-HRTimelineGroup
Capula Management Ltdin group Capula Management Ltd10,980$38.9K<0.01%new13F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
EntryPoint Capital, LLC10,587$37.5K0.02%-3,32213F-HRTimeline
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…10,340$36.6K<0.01%new13F-HRTimelineGroup
Valeo Financial Advisors, LLC10,000$35.4K<0.01%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…6,803$24.1K<0.01%-39,18413F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…6,700$23.7K<0.01%+1,63113F-HRTimelineGroup
Point72 (DIFC) Ltd5,047$17.9K<0.01%+25113F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\4,000$14.2K<0.01%013F-HRTimelineGroup
SIMPLEX TRADING, LLC4,162$14K<0.01%-13,65713F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…3,152$11.2K<0.01%new13F-HRTimeline
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…2,930$10.7K<0.01%+64613F-HRTimelineGroup
LORING WOLCOTT & COOLIDGE FIDUCIARY ADV…1,803$9.12K<0.01%013F-HRTimeline
Advisors Asset Management, Inc.2,573$9.11K<0.01%-1,32913F-HR/ATimeline
Caitong International Asset Management …2,229$7.89K0.01%new13F-HRTimeline
Steward Partners Investment Advisory, L…2,000$7.08K<0.01%013F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,700$6.02K<0.01%+26113F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS1,363$4.83K<0.01%+21413F-HRTimelineGroup
CWM, LLCin group CWM, LLC890$3K<0.01%013F-HRTimelineGroup
Dunhill Financial, LLC600$2.12K<0.01%013F-HRTimeline
North Capital, Inc.500$1.77K<0.01%13F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN300$1.06K<0.01%013F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC285$1.01K<0.01%-21013F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.266$1K<0.01%013F-HRTimelineGroup
Physician Wealth Advisors, Inc.274$970<0.01%new13F-HRTimeline
COLDSTREAM CAPITAL MANAGEMENT INC238$843<0.01%new13F-HRTimeline
HARBOUR INVESTMENTS, INC.90$319<0.01%013F-HRTimeline
Catherine Avery Investment Management L…87$308<0.01%013F-HRTimeline
SALEM INVESTMENT COUNSELORS INC55$195<0.01%013F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…53$188<0.01%013F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…25$89<0.01%013F-HRTimelineGroup
SBI Securities Co., Ltd.1$4<0.01%013F-HRTimeline
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.

Events

  • MILNE GEORGE M JR sold 30,000 AMLX shares on 2026-10-05, Form 4 filed 2026-10-07. 0001193125-26-416950

    Accepted , ingested