13F-HR filed by Ikarian Capital, LLC
Ikarian Capital, LLC filed this 13F-HR for the quarter ended 2024-12-31, filed 2025-02-14, with 171 holding rows worth $735,256,871.
- Accession
- 0001420506-25-000610
- Filer
- CIK 1778253
- Filed
- 2025-02-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2024
A holdings report, 171 entries on the cover page, a total value of $735,256,871 stated on the cover page (in dollars after the unit check, H1), rows summing to $735,256,871 with VALUE read as dollars as filed, 13F file number 028-19721. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| SPDR SER TR | 78464A870 | S&P BIOTECH | 750,000 | $67,545,000 | dollars as filed | put |
| SPDR SER TR | 78464A870 | S&P BIOTECH | 700,000 | $63,042,000 | dollars as filed | call |
| TYSON FOODS INC CL A | 902494103 | Stock | 630,000 | $36,187,200 | dollars as filed | put |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 607,689 | $33,647,740 | dollars as filed | |
| CRINETICS PHARMACEUTICALS INC COM | 22663K107 | Stock | 516,431 | $26,405,117 | dollars as filed | |
| Amgen Inc. | 031162100 | COM | 74,000 | $19,287,360 | dollars as filed | call |
| BRIDGEBIO PHARMA INC | 10806X102 | COM | 700,000 | $19,208,000 | dollars as filed | call |
| SCHOLAR ROCK HLDG CORP | 80706P103 | COM | 357,185 | $15,437,536 | dollars as filed | |
| BLUEPRINT MEDICINES CORP | 09627Y109 | COM | 169,374 | $14,772,801 | dollars as filed | |
| FORTE BIOSCIENCES INC | 34962G208 | COMMON STOCK | 609,225 | $13,835,500 | dollars as filed | |
| PILGRIMS PRIDE CORP COM | 72147K108 | Stock | 300,000 | $13,617,000 | dollars as filed | put |
| AVIDITY BIOSCIENCES INC COM | 05370A108 | Stock | 400,000 | $11,632,000 | dollars as filed | put |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 150,000 | $10,356,000 | dollars as filed | call |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 81,000 | $9,848,790 | dollars as filed | call |
| NEUMORA THERAPEUTICS INC. | 640979100 | COM | 900,000 | $9,540,000 | dollars as filed | call |
| VIRIDIAN THERAPEUTICS INC | 92790C104 | COM | 469,949 | $9,008,923 | dollars as filed | |
| ENLIVEN THERAPEUTICS INC COM | 29337E102 | Stock | 394,538 | $8,877,106 | dollars as filed | |
| TG THERAPEUTICS INC COM | 88322Q108 | Stock | 291,240 | $8,766,324 | dollars as filed | |
| AXSOME THERAPEUTICS INC. COM | 05464T104 | Stock | 100,000 | $8,461,000 | dollars as filed | call |
| INSMED INC COM PAR $.01 | 457669307 | Stock | 119,800 | $8,270,991 | dollars as filed | |
| CAL MAINE FOODS INC COM NEW | 128030202 | Stock | 75,000 | $7,719,000 | dollars as filed | put |
| STRUCTURE THERAPEUTICS INC COMP | 86366E106 | EQUITY | 284,085 | $7,704,386 | dollars as filed | |
| GINKGO BIOWORKS HOLDINGS INC | 37611X209 | COMMON STOCK | 769,700 | $7,558,454 | dollars as filed | call |
| ULTRAGENYX PHARMACEUTICAL IN | 90400D108 | COM | 178,989 | $7,530,068 | dollars as filed | |
| IMMUNOVANT INC | 45258J102 | COM | 300,000 | $7,431,000 | dollars as filed | call |
| CATALYST PHARMACEUTICALS INC | 14888U101 | COM | 349,649 | $7,297,174 | dollars as filed | |
| AVALO THERAPEUTICS INC | 05338F306 | COMMON STOCK | 970,259 | $7,209,024 | dollars as filed | |
| CYTOKINETICS INC | 23282W605 | COM NEW | 149,982 | $7,055,153 | dollars as filed | |
| DYNE THERAPEUTICS INC COM | 26818M108 | Stock | 280,800 | $6,615,648 | dollars as filed | put |
| VIR BIOTECHNOLOGY INC | 92764N102 | COM | 897,862 | $6,590,308 | dollars as filed | |
| TECTONIC THERAPEUTIC INC | 878972108 | COMMON STOCK | 142,328 | $6,571,283 | dollars as filed | |
| SPYRE THERAPEUTICS INC | 00773J202 | COM NEW | 282,159 | $6,568,661 | dollars as filed | |
| BRIDGEBIO PHARMA INC | 10806X102 | COM | 215,713 | $5,919,165 | dollars as filed | |
| KODIAK SCIENCES INC | 50015M109 | COM | 576,166 | $5,732,852 | dollars as filed | |
| ARCUS BIOSCIENCES INC | 03969F109 | COM | 378,363 | $5,633,825 | dollars as filed | |
| AKERO THERAPEUTICS INC | 00973Y108 | COM | 199,000 | $5,536,180 | dollars as filed | put |
| BEONE MEDICINES LTD SPONSORED ADS | 07725L102 | ADR | 29,800 | $5,504,358 | dollars as filed | call |
| BRIGHT MINDS BIOSCIENCES INC | 10919W405 | COMMON STOCK | 152,211 | $5,482,641 | dollars as filed | |
| VIR BIOTECHNOLOGY INC | 92764N102 | COM | 720,300 | $5,287,002 | dollars as filed | call |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 205,500 | $5,192,985 | dollars as filed | put |
| CAPRICOR THERAPEUTICS INC | 14070B309 | COMMON STOCK | 361,100 | $4,983,180 | dollars as filed | call |
| ELEDON PHARMACEUTICALS INC | 28617k101 | COM | 1,126,637 | $4,641,745 | dollars as filed | |
| ALPHA COGNITION INC | 02074J501 | COM NEW | 755,867 | $4,452,057 | dollars as filed | |
| SCHOLAR ROCK HLDG CORP | 80706P103 | COM | 102,100 | $4,412,762 | dollars as filed | call |
| LENZ THERAPEUTICS INC | 52635N103 | COM | 149,502 | $4,316,123 | dollars as filed | |
| REZOLUTE INC | 76200L309 | COMMON STOCK | 857,230 | $4,200,427 | dollars as filed | |
| MODERNA INC | 60770K107 | COM | 100,000 | $4,158,000 | dollars as filed | put |
| SAREPTA THERAPEUTICS INC | 803607100 | COM | 34,087 | $4,144,639 | dollars as filed | |
| CAPRICOR THERAPEUTICS INC | 14070B309 | COMMON STOCK | 300,000 | $4,140,000 | dollars as filed | put |
| EVOLUS INC | 30052C107 | COM | 373,265 | $4,120,847 | dollars as filed | |
| ANAPTYSBIO INC | 032724106 | COM | 310,800 | $4,114,992 | dollars as filed | put |
| MINERALYS THERAPEUTICS INC | 603170101 | COM | 332,390 | $4,091,722 | dollars as filed | |
| NUVALENT INC COM | 670703107 | Stock | 52,216 | $4,087,469 | dollars as filed | |
| CORVUS PHARMACEUTICALS INC | 221015100 | COM | 754,400 | $4,036,040 | dollars as filed | call |
| JANUX THERAPEUTICS INC | 47103J105 | COM | 74,691 | $3,998,956 | dollars as filed | |
| VERONA PHARMA PLC | 925050106 | SPONSORED ADS | 80,000 | $3,715,200 | dollars as filed | |
| NEUMORA THERAPEUTICS INC. | 640979100 | COM | 350,000 | $3,710,000 | dollars as filed | put |
| CYBIN INC | 23256X407 | COM NEW | 397,175 | $3,503,084 | dollars as filed | |
| ARCTURUS THERAPEUTICS HLDGS | 03969T109 | COM | 200,000 | $3,394,001 | dollars as filed | |
| SOLENO THERAPEUTICS INC | 834203309 | COM | 75,000 | $3,371,250 | dollars as filed | put |
| VIRIDIAN THERAPEUTICS INC | 92790C104 | COM | 175,100 | $3,356,667 | dollars as filed | call |
| ANAPTYSBIO INC | 032724106 | COM | 250,000 | $3,310,000 | dollars as filed | call |
| LEXEO THERAPEUTICS INC | 52886X107 | COMMON STOCK | 499,301 | $3,285,401 | dollars as filed | |
| ABEONA THERAPEUTICS INC | 00289Y206 | COM NEW | 533,581 | $2,972,046 | dollars as filed | |
| AVIDITY BIOSCIENCES INC COM | 05370A108 | Stock | 100,000 | $2,908,000 | dollars as filed | call |
| RELAY THERAPEUTICS INC COM | 75943R102 | Stock | 693,308 | $2,856,429 | dollars as filed | |
| ROCKET PHARMACEUTICALS INC | 77313F106 | COM | 221,911 | $2,789,421 | dollars as filed | |
| PROTAGONIST THERAPEUTICS | 74366E102 | COM | 70,000 | $2,701,999 | dollars as filed | |
| CORVUS PHARMACEUTICALS INC | 221015100 | COM | 500,000 | $2,675,000 | dollars as filed | put |
| ALIGOS THERAPEUTICS INC | 01626L204 | COM NEW | 64,300 | $2,561,712 | dollars as filed | |
| ZEVRA THERAPEUTICS INC COM NEW | 488445206 | Stock | 292,772 | $2,441,719 | dollars as filed | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 62,052 | $2,432,438 | dollars as filed | |
| NOVAVAX INC | 670002401 | COM NEW | 300,000 | $2,412,000 | dollars as filed | call |
| Ventyx Biosciences Inc | 92332V107 | Common Stock | 1,092,590 | $2,392,772 | dollars as filed | |
| TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS | 881624209 | ADR | 100,000 | $2,204,000 | dollars as filed | call |
| ONKURE THERAPEUTICS INC | 68277Q105 | COM CL A | 253,754 | $2,182,285 | dollars as filed | |
| MONTE ROSA THERAPEUTICS INC | 61225M102 | COM | 311,575 | $2,162,331 | dollars as filed | |
| ACELYRIN INC | 00445A100 | COM | 676,608 | $2,124,549 | dollars as filed | |
| ARCUS BIOSCIENCES INC | 03969F109 | COM | 141,000 | $2,099,490 | dollars as filed | call |
| HARROW INC | 415858109 | COM | 58,300 | $1,955,965 | dollars as filed | call |
| CARDIFF ONCOLOGY INC | 14147L108 | COM | 450,000 | $1,953,000 | dollars as filed | |
| SANGAMO THERAPEUTICS INC | 800677106 | COM | 1,860,179 | $1,897,384 | dollars as filed | |
| NEKTAR THERAPEUTICS | 640268108 | COM | 2,029,028 | $1,886,995 | dollars as filed | |
| PROTARA THERAPEUTICS INC | 74365U107 | COM STK | 350,489 | $1,850,582 | dollars as filed | |
| ALECTOR INC | 014442107 | COMMON STOCK | 950,000 | $1,795,501 | dollars as filed | |
| TERNS PHARMACEUTICALS INC COM | 880881107 | Stock | 308,491 | $1,709,041 | dollars as filed | |
| BIOMEA FUSION INC | 09077A106 | CMN | 431,100 | $1,672,668 | dollars as filed | put |
| ACHILLES THERAPEUTICS PL-ADR | 00449L102 | COM | 1,441,141 | $1,642,901 | dollars as filed | |
| IMMUNIC INC | 4525EP101 | COM | 1,614,170 | $1,614,170 | dollars as filed | |
| GALECTIN THERAPEUTICS INC | 363225202 | COMMON STOCK | 1,200,000 | $1,548,000 | dollars as filed | put |
| GALECTIN THERAPEUTICS INC | 363225202 | COMMON STOCK | 1,200,000 | $1,548,000 | dollars as filed | call |
| ALTO NEUROSCIENCE INC COM SHS | 02157Q109 | Stock | 350,000 | $1,480,500 | dollars as filed | |
| IBIO INC | 451033708 | CMN | 599,913 | $1,469,787 | dollars as filed | |
| CIDARA THERAPEUTICS INC | 171757206 | COM NEW | 53,940 | $1,449,907 | dollars as filed | |
| Tourmaline Bio Inc | 89157D105 | Common Stock | 67,927 | $1,377,559 | dollars as filed | |
| SPRINGWORKS THERAPEUTICS INC | 85205L107 | COM | 37,519 | $1,355,561 | dollars as filed | |
| TREVI THERAPEUTICS INC COM | 89532M101 | Stock | 325,000 | $1,339,000 | dollars as filed | |
| DELCATH SYSTEMS INC | 24661P807 | COMMON STOCK | 100,365 | $1,208,394 | dollars as filed | |
| SOLID BIOSCIENCES INC | 83422E204 | COMMON STOCK | 300,000 | $1,200,000 | dollars as filed | call |
| ALTIMMUNE INC | 02155H200 | COM NEW | 165,700 | $1,194,697 | dollars as filed | put |
| ALTIMMUNE INC | 02155H200 | COM NEW | 165,700 | $1,194,697 | dollars as filed | call |
| JASPER THERAPEUTICS INC | 471871202 | COM NEW | 55,107 | $1,178,187 | dollars as filed | |
| ALLAKOS INC | 01671P100 | COM | 971,950 | $1,176,059 | dollars as filed | |
| LEXICON PHARMACEUTICALS INC | 528872302 | COMMON STOCK | 1,550,000 | $1,144,675 | dollars as filed | |
| Milestone Pharmaceuticals Inc | 59935V107 | COM | 466,030 | $1,099,830 | dollars as filed | |
| SANA BIOTECHNOLOGY INC | 799566104 | COM | 650,000 | $1,059,500 | dollars as filed | call |
| THIRD HARMONIC BIO INC | 88427A107 | COM | 100,000 | $1,029,001 | dollars as filed | |
| VERVE THERAPEUTICS INC | 92539P101 | COM | 169,991 | $958,748 | dollars as filed | |
| PYXIS ONCOLOGY INC COMMON STOCK | 747324101 | Stock | 613,253 | $956,675 | dollars as filed | |
| FULCRUM THERAPEUTICS INC | 359616109 | COMMON STOCK | 200,096 | $940,452 | dollars as filed | |
| CARTESIAN THERAPEUTICS INC | 816212302 | COMMON STOCK | 52,166 | $934,294 | dollars as filed | |
| TRAWS PHARMA INC | 68232V884 | COM NEW | 98,493 | $874,618 | dollars as filed | |
| ACLARIS THERAPEUTICS INC COM | 00461U105 | Stock | 350,000 | $868,001 | dollars as filed | |
| VIGIL NEUROSCIENCE INC | 92673K108 | COM | 500,000 | $850,000 | dollars as filed | |
| TYRA BIOSCIENCES INC | 90240B106 | COMMON STOCK | 60,000 | $834,000 | dollars as filed | |
| LYELL IMMUNOPHARMA INC | 55083R104 | COM | 1,276,037 | $816,664 | dollars as filed | |
| SANA BIOTECHNOLOGY INC | 799566104 | COM | 500,000 | $815,000 | dollars as filed | put |
| COMPASS PATHWAYS PLC | 20451W101 | SPONSORED ADS | 202,894 | $766,939 | dollars as filed | |
| AMYLYX PHARMACEUTICALS INC | 03237H101 | COM | 201,187 | $760,486 | dollars as filed | |
| KEZAR LIFE SCIENCES INC | 49372L209 | COM NEW | 106,901 | $718,375 | dollars as filed | |
| NURIX THERAPEUTICS INC | 67080M103 | COMMON STOCK | 34,985 | $659,116 | dollars as filed | |
| BIOMX INC | 09090D301 | COM | 892,976 | $651,962 | dollars as filed | |
| INHIBRX BIOSCIENCES INC | 45720N103 | COM | 42,122 | $648,679 | dollars as filed | |
| Aethlon Medical Inc OLD | 00808Y406 | COM NEW | 750,000 | $645,001 | dollars as filed | |
| IMMUNIC INC | 4525EP101 | COM | 635,800 | $635,800 | dollars as filed | call |
| Veru Inc | 92536C103 | Common Stock | 945,239 | $614,878 | dollars as filed | |
| CORBUS PHARMACEUTICALS | 21833P301 | COM NEW | 51,431 | $606,885 | dollars as filed | |
| ITEOS THERAPEUTICS INC | 46565G104 | COM | 78,585 | $603,533 | dollars as filed | |
| SANA BIOTECHNOLOGY INC | 799566104 | COM | 365,000 | $594,949 | dollars as filed | |
| OLEMA PHARMACEUTICALS INC | 68062P106 | COM | 91,994 | $536,324 | dollars as filed | |
| ACUMEN PHARMACEUTICALS INC | 00509G209 | CMN | 265,769 | $457,123 | dollars as filed | |
| MIND MEDICINE MINDMED INC | 60255C885 | COM NEW | 62,691 | $436,329 | dollars as filed | |
| SPRUCE BIOSCIENCES INC | 85209E109 | COM | 1,000,000 | $420,000 | dollars as filed | |
| TRAVERE THERAPEUTICS INC | 89422G107 | COM | 22,600 | $393,692 | dollars as filed | |
| ELEVATION ONCOLOGY INC COM | 28623U101 | Stock | 690,050 | $388,222 | dollars as filed | |
| CHEMOMAB THERAPEUTICS LTD | 16385C104 | SPONSORED ADS | 213,052 | $385,624 | dollars as filed | |
| ABEONA THERAPEUTICS INC | 00289Y206 | COM NEW | 65,000 | $362,050 | dollars as filed | call |
| PERSPECTIVE THERAPEUTICS INC | 46489V302 | COMMON STOCK | 108,300 | $345,476 | dollars as filed | |
| PERSPECTIVE THERAPEUTICS INC | 46489V302 | COMMON STOCK | 107,200 | $341,968 | dollars as filed | put |
| SENSEI BIOTHERAPEUTICS INC | 81728A108 | COM | 649,963 | $318,546 | dollars as filed | |
| VOYAGER THERAPEUTICS INC | 92915B106 | COMMON STOCK | 55,766 | $316,194 | dollars as filed | |
| CLIMB BIO INC | 28658R106 | COMMON STOCK | 175,088 | $315,159 | dollars as filed | |
| AVENUE THERAPEUTICS INC | 05360L403 | COM NEW | 140,000 | $280,000 | dollars as filed | |
| KARYOPHARM THERAPEUTICS INC | 48576U106 | COM | 408,899 | $276,539 | dollars as filed | |
| ANEBULO PHARMACEUTICALS INC | 034569103 | COM | 157,720 | $264,971 | dollars as filed | |
| MACROGENICS INC | 556099109 | COM | 80,071 | $260,232 | dollars as filed | |
| VISTAGEN THERAPEUTICS INC | 92840H400 | COM | 77,616 | $228,968 | dollars as filed | |
| LARIMAR THERAPEUTICS INC | 517125100 | COM | 58,526 | $226,496 | dollars as filed | |
| NUVATION BIO INC COM CL A | 67080N101 | Stock | 83,407 | $221,863 | dollars as filed | |
| LYRA THERAPEUTICS INC | 55234L105 | COM | 1,058,148 | $218,403 | dollars as filed | |
| QUOIN PHARMACEUTICALS ADR | 74907L300 | COM | 275,000 | $178,942 | dollars as filed | |
| AEON BIOPHARMA INC | 00791X100 | CL A | 257,563 | $139,085 | dollars as filed | |
| MONOPAR THERAPEUTICS INC | 61023L207 | COMMON STOCK | 5,908 | $129,976 | dollars as filed | |
| APELLIS PHARMACEUTICALS INC | 03753U106 | COM | 3,594 | $114,685 | dollars as filed | |
| HOOKIPA PHARMA INC | 43906K209 | COM NEW | 52,996 | $106,522 | dollars as filed | |
| Tempest Therapeutics, Inc. | 87978U108 | Common Stock | 105,285 | $87,860 | dollars as filed | |
| AUTONOMIX MED INC | 05330T205 | COM NEW | 20,000 | $75,200 | dollars as filed | |
| STOKE THERAPEUTICS INC | 86150R107 | COM | 6,798 | $74,982 | dollars as filed | |
| SAGIMET BIOSCIENCES INC A | 786700104 | COMMON STOCK | 11,984 | $53,929 | dollars as filed | |
| CANDEL THERAPEUTICS INC | 137404109 | COMMON STOCK | 3,600 | $31,248 | dollars as filed | put |
| CANDEL THERAPEUTICS INC | 137404109 | COMMON STOCK | 3,600 | $31,248 | dollars as filed | call |
| SYNLOGIC INC | 87166L209 | COM | 20,422 | $27,978 | dollars as filed | |
| RELMADA THERAPEUTICS INC | 75955J402 | COMMON STOCK | 40,270 | $20,940 | dollars as filed | |
| IMMUNOVANT INC | 45258J102 | COM | 600 | $14,862 | dollars as filed | |
| BRAINSTORM CELL THERAPEUTICS | 10501E300 | COM | 6,016 | $13,657 | dollars as filed | |
| CANDEL THERAPEUTICS INC | 137404109 | COMMON STOCK | 1,400 | $12,151 | dollars as filed | |
| CYTOMX THERAPEUTICS INC | 23284F105 | COMMON STOCK | 8,924 | $9,192 | dollars as filed | |
| EDGEWISE THERAPEUTICS INC | 28036F105 | COM | 200 | $5,340 | dollars as filed | put |
| GLYCOMIMETICS INC | 38000Q102 | COM | 6,501 | $1,619 | dollars as filed | |
| 4D MOLECULAR THERAPEUTICS INC COM | 35104E100 | Stock | 40 | $223 | dollars as filed | |
| GALECTIN THERAPEUTICS INC | 363225202 | COMMON STOCK | 100 | $129 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001420506-25-000610 | this filing | 2025-02-14 | acceptance time not in the bulk data set |