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Disclosery

AMLX AMYLYX PHARMACEUTICALS INC

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COM (common), issuer CIK 1658551

129 managers (132 13F filers) reported a position in AMLX shares at 2025-06-30, 81,690,010 shares in all. 30 filers opened a position and 36 filers sold out during the quarter.

Managers
129
13F filers
132
New
30
Added
37
Reduced
37
Sold out
36
Shares held by filers
81,690,010

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

The latest Form 4 transactions, non-derivative.
OwnerDateSharesPriceFiling
MILNE GEORGE M JRdirector2026-10-05-30,000 S$27.6968Form 4

13F holders, Q2 2025

Filers in the available 13F reports with a share position at 2025-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…8,800,000$56.4M0.1%+3,102,39513F-HRTimelineGroup
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC7,902,365$50.7M1.9%+28,01713F-HRTimelineGroup
TCG Crossover Management, LLC5,943,812$38.1M4.35%013F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.5,510,189$35.3M<0.01%+3,122,78013F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.4,536,266$29.1M0.07%+3,619,30013F-HRTimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding4,519,151$29M+380,883Timeline
Saturn V Capital Management LP3,260,570$20.9M8.47%+834,13413F-HRTimeline
FMR LLCin group FMR LLC3,048,019$19.5M<0.01%+1,890,03113F-HRTimelineGroup
Nantahala Capital Management, LLCin group Nantahala Capital Management,…2,934,405$18.8M1.33%013F-HRTimelineGroup
683 Capital Management, LLCin group 683 Capital Management, LLC2,160,000$13.8M1.4%-251,40013F-HRTimelineGroup
Almitas Capital LLC2,122,597$13.6M3.43%013F-HRTimeline
GREAT POINT PARTNERS LLC2,000,000$12.8M8.34%+188,00413F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,692,413$10.9M<0.01%+886,25213F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC1,512,058$9.69M0.01%-1,569,79513F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC1,297,982$8.32M<0.01%-704,97913F-HRTimelineGroup
Driehaus Capital Management LLC1,264,997$8.11M0.06%new13F-HRTimeline
UBS Group AGin group UBS Group AG1,253,344$8.03M<0.01%-135,08313F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC1,242,927$7.97M0.01%-1,514,84913F-HRTimelineGroup
Boxer Capital Management, LLCin group Boxer Capital Management, LLC1,225,000$7.85M3.95%-525,00013F-HR/ATimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC1,205,101$7.72M1.25%-266,48613F-HRTimelineGroup
Woodline Partners LP1,200,290$7.69M0.04%-409,15713F-HRTimeline
Connor, Clark & Lunn Investment Managem…1,154,485$7.4M0.03%-45,20613F-HRTimeline
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding1,028,846$6.59M-383,007Timeline
STATE STREET CORPin group STATE STREET CORP1,008,909$6.47M<0.01%+747,12613F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP820,164$5.26M<0.01%+680,83213F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc738,657$4.73M0.01%-1,691,70113F-HRTimelineGroup
PFM Health Sciences, LP732,256$4.69M0.41%-101,87913F-HRTimeline
Parkman Healthcare Partners LLC650,000$4.17M0.48%new13F-HRTimeline
Schonfeld Strategic Advisors LLC646,443$4.14M0.03%+529,30313F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\616,919$3.95M<0.01%+46,06213F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co588,411$3.77M<0.01%+215,55813F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.586,883$3.76M<0.01%+541,18913F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC569,083$3.65M0.01%+326,97613F-HRTimelineGroup
Rock Springs Capital Management LP499,764$3.2M0.2%+156,53613F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY486,893$3.12M<0.01%+12,47513F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/451,808$2.9M<0.01%-342,54613F-HRTimelineGroup
Qube Research & Technologies Ltd438,026$2.81M<0.01%-504,86513F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC396,200$2.54M<0.01%-118,90013F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP373,739$2.4M<0.01%+250,16313F-HRTimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC313,200$2.01M0.05%-34,80013F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…288,618$1.85M<0.01%-2,06413F-HRTimelineGroup
Alpha Wave Global, LP275,842$1.77M0.19%+88,53113F-HRTimeline
J. Goldman & Co LP258,600$1.66M0.05%new13F-HRTimeline
Y-Intercept (Hong Kong) Ltd240,379$1.54M0.04%new13F-HRTimeline
Tetragon Partners GP Ltdin group Tetragon Partners GP Ltd218,750$1.4M0.25%new13F-HRTimelineGroup
Aldebaran Capital, LLC217,827$1.4M1.38%-41,42613F-HRTimeline
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.203,930$1.31M<0.01%+1,14513F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC186,986$1.2M<0.01%-144,19913F-HRTimelineGroup
GSA CAPITAL PARTNERS LLP170,533$1.09M0.08%+147,44813F-HRTimeline
Nuveen, LLCin group TIAA155,536$997K<0.01%new13F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.151,502$971K<0.01%-118,50413F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp150,837$967K<0.01%new13F-HRTimelineGroup
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/143,512$920K<0.01%013F-HRTimelineGroup
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC134,380$861K<0.01%+27,36613F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC130,274$835K<0.01%-7,13113F-HR/ATimelineGroup
Cubist Systematic Strategies, LLC123,242$790K0.01%+40,11213F-HRTimeline
Allostery Investments LP120,119$770K9.81%-145,98013F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…110,846$711K<0.01%-1,360,07913F-HRTimelineGroup
RHUMBLINE ADVISERS100,576$645K<0.01%new13F-HRTimeline
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC100,000$641K0.03%013F-HRTimelineGroup
Informed Momentum Co LLC99,960$641K0.1%new13F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC95,219$610K<0.01%+82,41413F-HRTimelineGroup
Kennondale Capital Management LLC95,165$610K0.62%-107,57813F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/91,392$586K<0.01%+33,69213F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO87,989$564K<0.01%+33,92013F-HRTimelineGroup
Hennion & Walsh Asset Management, Inc.56,831$364K0.01%-26,40513F-HRTimeline
CANTOR FITZGERALD, L. P.in group CANTOR FITZGERALD, L. P.50,000$320K0.01%-50,00013F-HRTimelineGroup
Mariner, LLCin group Mariner, LLC48,668$312K<0.01%-2,23813F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC47,800$306K<0.01%new13F-HR/ATimelineGroup
Centiva Capital, LP45,464$291K0.02%+17,24213F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…42,929$275K<0.01%new13F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding41,430$266K+38,500Timeline
Squarepoint Ops LLCin group Squarepoint Ops LLC40,643$261K<0.01%-35,20613F-HR/ATimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN38,101$244K<0.01%+37,80113F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC36,315$233K<0.01%new13F-HRTimeline
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC35,752$229K<0.01%-2,04413F-HRTimelineGroup
Graham Capital Management, L.P.34,153$219K0.01%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC31,098$199K<0.01%-432,14213F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.30,600$196K<0.01%new13F-HRTimeline
Quadrature Capital Ltdin group Quadrature Capital Ltd29,430$188K<0.01%+16,68613F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …25,999$167K<0.01%new13F-HRTimelineGroup
GROUP ONE TRADING LLC25,856$166K0.01%-17,37813F-HRTimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC25,700$165K<0.01%-130,00013F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC23,320$149K<0.01%new13F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND21,900$140K<0.01%new13F-HR/ATimeline
PARSONS CAPITAL MANAGEMENT INC/RI21,645$139K0.01%013F-HRTimeline
Premier Path Wealth Partners, LLC20,265$130K0.02%013F-HRTimeline
Marex Group Ltdin group Marex Group Ltd20,000$128K<0.01%013F-HRTimelineGroup
BROWN ADVISORY INCin group BROWN ADVISORY INC19,930$128K<0.01%013F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC19,476$125K<0.01%new13F-HRTimelineGroup
China Universal Asset Management Co., L…17,904$115K0.01%+71613F-HRTimeline
ProShare Advisors LLC17,551$113K<0.01%new13F-HRTimeline
Police & Firemen's Retirement System of…15,992$103K<0.01%new13F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC15,620$100K<0.01%+42013F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA12,133$78K<0.01%+28313F-HR/ATimelineGroup
TUDOR INVESTMENT CORP ET AL12,073$77.4K<0.01%-21,35513F-HRTimeline
Valeo Financial Advisors, LLC10,000$64.1K<0.01%013F-HR/ATimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…7,467$47.9K<0.01%+66413F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc7,402$47.4K<0.01%new13F-HRTimelineGroup
STRS OHIO7,300$46.8K<0.01%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS7,267$46.6K<0.01%+5,90413F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…7,081$45.4K<0.01%new13F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…6,229$39.9K<0.01%-47113F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…4,328$27.7K<0.01%new13F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\4,000$25.6K<0.01%013F-HRTimelineGroup
Caitong International Asset Management …2,913$18.7K0.01%+68413F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…2,823$18.1K<0.01%-32913F-HRTimeline
Global Retirement Partners, LLC2,500$16K<0.01%13F-HRTimeline
AMALGAMATED BANK2,369$15K<0.01%new13F-HRTimeline
Steward Partners Investment Advisory, L…2,000$12.8K<0.01%013F-HRTimeline
LORING WOLCOTT & COOLIDGE FIDUCIARY ADV…1,803$11.6K<0.01%013F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,700$10.9K<0.01%013F-HRTimeline
CWM, LLCin group CWM, LLC890$6K<0.01%013F-HRTimelineGroup
Dunhill Financial, LLC600$3.85K<0.01%013F-HRTimeline
Sterling Capital Management LLC552$3.54K<0.01%new13F-HR/ATimeline
North Capital, Inc.500$3.21K<0.01%013F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.266$2K<0.01%013F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC285$1.83K<0.01%013F-HRTimeline
Physician Wealth Advisors, Inc.274$1.76K<0.01%013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.240$1.54K<0.01%new13F-HR/ATimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC104$667<0.01%new13F-HRTimelineGroup
HARBOUR INVESTMENTS, INC.90$577<0.01%013F-HRTimeline
Catherine Avery Investment Management L…87$558<0.01%013F-HRTimeline
SALEM INVESTMENT COUNSELORS INC55$353<0.01%013F-HR/ATimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…53$340<0.01%013F-HRTimelineGroup
Brooklyn Investment Group42$270<0.01%new13F-HR/ATimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…25$160<0.01%013F-HRTimelineGroup
SBI Securities Co., Ltd.1$6<0.01%013F-HRTimeline
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.

Events

  • MILNE GEORGE M JR sold 30,000 AMLX shares on 2026-10-05, Form 4 filed 2026-10-07. 0001193125-26-416950

    Accepted , ingested