Essex Woodlands Management, Inc. More: the full row for Essex Woodlands Management, Inc. 7,714,709 $5.79M 2.28% 0 13F-HR Timeline Nantahala Capital Management, LLC More: the full row for Nantahala Capital Management, LLC 5,894,114 $4.42M 0.27% +750,000 13F-HR/A Timeline Stonepine Capital Management, LLC More: the full row for Stonepine Capital Management, LLC 2,662,427 $2M 1.52% +45,175 13F-HR/A Timeline SILVERARC CAPITAL MANAGEMENT, LLC in group SILVERARC CAPITAL MANAGEMENT,… More: the full row for SILVERARC CAPITAL MANAGEMENT, LLC 2,137,201 $1.6M 0.18% -122,111 13F-HR Timeline Group VANGUARD GROUP INC group of 3 filers holding More: the full row for VANGUARD GROUP INC 1,785,960 $1.34M +29,070 Timeline DAFNA Capital Management LLC More: the full row for DAFNA Capital Management LLC 1,441,029 $1.08M 0.21% 0 13F-HR Timeline PERKINS CAPITAL MANAGEMENT INC More: the full row for PERKINS CAPITAL MANAGEMENT INC 1,375,042 $1.03M 0.78% -43,286 13F-HR Timeline Sio Capital Management, LLC More: the full row for Sio Capital Management, LLC 636,300 $477K 0.08% 0 13F-HR Timeline WealthTrust Axiom LLC More: the full row for WealthTrust Axiom LLC 457,734 $343K 0.08% +80,796 13F-HR Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 389,223 $292K <0.01% -65,836 13F-HR Timeline Group BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 374,516 $281K <0.01% -91,298 13F-HR Timeline Group UP STRATEGIC WEALTH INVESTMENT ADVISORS… More: the full row for UP STRATEGIC WEALTH INVESTMENT ADVISORS LLC 99,888 $91.4K 0.05% 0 13F-HR Timeline Embree Financial Group More: the full row for Embree Financial Group 90,906 $68.2K 0.01% -27,272 13F-HR Timeline NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 74,790 $56.1K <0.01% -99,608 13F-HR Timeline Group RAYMOND JAMES FINANCIAL INC in group RAYMOND JAMES FINANCIAL INC More: the full row for RAYMOND JAMES FINANCIAL INC 67,700 $50.8K <0.01% +18,000 13F-HR Timeline Group STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 63,383 $47.5K <0.01% 0 13F-HR Timeline Group RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 58,100 $43.6K <0.01% +5,500 13F-HR Timeline PNC Financial Services Group, Inc. in group PNC Financial Services Group,… More: the full row for PNC Financial Services Group, Inc. 53,612 $40.2K <0.01% 0 13F-HR Timeline Group Destiny Wealth Partners, LLC More: the full row for Destiny Wealth Partners, LLC 52,500 $38.3K 0.01% 0 13F-HR Timeline Ducere Wealth Management LLC More: the full row for Ducere Wealth Management LLC 51,000 $38.2K 0.01% +10,000 13F-HR Timeline JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 49,245 $36.9K <0.01% new 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 33,466 $25.1K <0.01% -1,026,058 13F-HR Timeline Group XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 29,558 $22.2K <0.01% +14,385 13F-HR Timeline Group TD Waterhouse Canada Inc. More: the full row for TD Waterhouse Canada Inc. 23,000 $16.6K <0.01% new 13F-HR Timeline PRIMORIS WEALTH ADVISORS, LLC More: the full row for PRIMORIS WEALTH ADVISORS, LLC 20,300 $15.2K 0.01% new 13F-HR Timeline GREAT VALLEY ADVISOR GROUP, INC. More: the full row for GREAT VALLEY ADVISOR GROUP, INC. 19,602 $14.7K <0.01% -101 13F-HR Timeline J.W. COLE ADVISORS, INC. More: the full row for J.W. COLE ADVISORS, INC. 16,250 $12.2K <0.01% new 13F-HR Timeline Atom Investors LP More: the full row for Atom Investors LP 15,473 $11.6K <0.01% new 13F-HR Timeline MERCER GLOBAL ADVISORS INC /ADV More: the full row for MERCER GLOBAL ADVISORS INC /ADV 14,828 $11.1K <0.01% new 13F-HR/A Timeline Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 13,612 $10.2K <0.01% +12,728 13F-HR Timeline Group HighTower Advisors, LLC More: the full row for HighTower Advisors, LLC 11,200 $8.4K <0.01% 0 13F-HR Timeline GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 10,383 $7.79K <0.01% new 13F-HR Timeline Group WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 4,200 $3.15K <0.01% 0 13F-HR Timeline Group Steward Partners Investment Advisory, L… More: the full row for Steward Partners Investment Advisory, LLC 1,991 $1.49K <0.01% 0 13F-HR Timeline CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 1,774 $1.33K <0.01% -748,226 13F-HR Timeline Group SIMPLEX TRADING, LLC More: the full row for SIMPLEX TRADING, LLC 1,276 $957 <0.01% +1,133 13F-HR Timeline SBI Securities Co., Ltd. More: the full row for SBI Securities Co., Ltd. 301 $226 <0.01% 0 13F-HR Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 210 $158 <0.01% -4 13F-HR Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 208 $156 <0.01% new 13F-HR Timeline Group OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 100 $75 <0.01% new 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 39 $28 <0.01% 0 13F-HR Timeline Group MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 37 $28 <0.01% new 13F-HR Timeline Group ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 59 $0 0% +1 13F-HR Timeline Group Value filed as zero, left out of ratios.