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Disclosery

PLRX PLIANT THERAPEUTICS INC

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COM (common), issuer CIK 1746473

83 managers (86 13F filers) reported a position in PLRX shares at 2026-06-30, 48,100,481 shares in all. 8 filers opened a position and 13 filers sold out during the quarter.

Managers
83
13F filers
86
New
8
Added
18
Reduced
26
Sold out
13
Shares held by filers
48,100,481

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2026

Filers in the available 13F reports with a share position at 2026-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC6,141,261$7M0.32%-1,87113F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC5,509,724$6.28M0.3%+2,924,59813F-HRTimelineGroup
VANGUARD GROUP INCgroup of 5 filers holding2,955,321$3.37M+89,334Timeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC2,416,508$2.75M<0.01%013F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP2,262,832$2.58M<0.01%+9,69413F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC2,142,226$2.44M<0.01%-1,084,37313F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC2,049,874$2.34M<0.01%+197,03213F-HRTimeline
Monaco Asset Management SAM1,938,747$2.21M0.82%013F-HRTimeline
Lynx1 Capital Management LPin group Lynx1 Capital Management LP1,798,070$2.05M0.24%new13F-HR/ATimelineGroup
BML Capital Management, LLC1,546,137$1.76M1.01%013F-HRTimeline
Prosight Management, LP1,370,233$1.56M0.27%-297,36713F-HRTimeline
Peapod Lane Capital LLC1,309,013$1.49M1.01%+20,43513F-HRTimeline
Woodline Partners LP1,296,534$1.48M<0.01%-370,29613F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.1,151,214$1.31M<0.01%+54,78413F-HRTimelineGroup
Ikarian Capital, LLC1,000,000$1.14M0.19%new13F-HRTimeline
Eversept Partners, LP891,425$1.02M0.06%013F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP835,124$952K<0.01%-160,84913F-HRTimelineGroup
Redmile Group, LLCin group Redmile Group, LLC772,126$880K0.06%013F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO681,647$784K<0.01%-180,17613F-HRTimelineGroup
JACOBS LEVY EQUITY MANAGEMENT, INC643,120$733K<0.01%-75,42313F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC578,577$660K<0.01%+161,30313F-HRTimelineGroup
UBS Group AGin group UBS Group AG571,760$652K<0.01%-486,19413F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC559,447$638K<0.01%-621,07113F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC553,630$631K0.01%013F-HRTimeline
Connor, Clark & Lunn Investment Managem…536,081$611K<0.01%+18,62813F-HRTimeline
BESSEMER GROUP INCin group BESSEMER GROUP INC532,079$606K<0.01%013F-HRTimelineGroup
DAFNA Capital Management LLC487,000$555K0.11%013F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd440,844$503K0.01%-59,99413F-HRTimelineGroup
Laurion Capital Management LP412,796$471K0.03%013F-HRTimeline
TORNO CAPITAL, LLC351,445$401K0.03%+1,44513F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
BOOTHBAY FUND MANAGEMENT, LLC303,000$345K0.01%new13F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY298,976$341K<0.01%-206,76313F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO297,291$339K<0.01%013F-HRTimelineGroup
Verdad Advisers, LP281,343$321K0.31%+183,02313F-HRTimeline
ArrowMark Colorado Holdings LLC281,189$321K0.01%013F-HRTimeline
NANO CAP NEW MILLENNIUM GROWTH FUND L P275,000$314K0.24%013F-HRTimeline
STATE STREET CORPin group STATE STREET CORP253,418$289K<0.01%013F-HRTimelineGroup
Stonepine Capital Management, LLC230,538$263K0.2%+5,88813F-HR/ATimeline
Rangeley Capital, LLC225,000$256K0.24%013F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC208,585$238K<0.01%-388,25213F-HRTimelineGroup
Marquette Asset Management, LLC174,500$199K0.03%new13F-HRTimeline
HighMark Wealth Management LLC166,224$189K0.06%013F-HRTimeline
GSA CAPITAL PARTNERS LLP162,206$185K0.01%-239,88613F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC129,951$148K<0.01%-226,84313F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP125,060$143K<0.01%-29,11613F-HRTimelineGroup
ALGERT GLOBAL LLC123,402$141K<0.01%+38,95013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.114,924$131K<0.01%013F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.104,678$119K<0.01%-10,54013F-HRTimelineGroup
Bond & Devick Financial Network, Inc.100,160$114K0.03%013F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP99,773$114K<0.01%013F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC55,129$62.8K<0.01%013F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC40,814$46.5K<0.01%-122,40113F-HRTimelineGroup
Headlands Technologies LLC33,688$38.4K<0.01%new13F-HRTimeline
Quadrature Capital Ltdin group Quadrature Capital Ltd33,280$37.9K<0.01%-17,70113F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL29,729$33.9K<0.01%013F-HRTimeline
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.29,055$33.1K<0.01%-33,59613F-HRTimelineGroup
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF O…28,500$32.5K<0.01%013F-HRTimeline
Spark Investment Management LLC22,600$25.8K0.05%new13F-HRTimeline
Blackstone Inc.in group Blackstone Inc.22,206$25.3K<0.01%013F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.20,073$22.9K<0.01%-26,98113F-HRTimelineGroup
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …18,065$20.6K<0.01%013F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp16,032$18.3K<0.01%+20813F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…15,480$17.6K<0.01%-37,47613F-HRTimelineGroup
NewEdge Advisors, LLC15,000$17.1K<0.01%new13F-HRTimeline
Fiduciary Trust Coin group Fiduciary Trust Co11,620$13.2K<0.01%013F-HRTimelineGroup
Qube Research & Technologies Ltd10,033$11.4K<0.01%-93313F-HRTimeline
SIMPLEX TRADING, LLC4,925$5.61K<0.01%-43,12913F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA995$2K<0.01%-213F-HRTimelineGroup
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…660$752<0.01%013F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS657$749<0.01%013F-HRTimelineGroup
HARBOUR INVESTMENTS, INC.590$672<0.01%+10213F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC426$486<0.01%+39213F-HRTimelineGroup
FMR LLCin group FMR LLC419$478<0.01%-10513F-HRTimelineGroup
SBI Securities Co., Ltd.300$342<0.01%013F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN50$57<0.01%013F-HRTimelineGroup
Truvestments Capital LLC50$57<0.01%013F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…36$41<0.01%013F-HRTimeline
Caitong International Asset Management …8$9<0.01%+413F-HRTimeline
Farther Finance Advisors, LLC5$6<0.01%013F-HRTimeline
FIFTH THIRD BANCORPin group FIFTH THIRD BANK, NATIONAL AS…4$5<0.01%013F-HRTimelineGroup
IFG Advisory, LLC4$5<0.01%new13F-HRTimeline
Global Retirement Partners, LLC4$5<0.01%13F-HRTimeline
Capital Advisors, Ltd. LLC31$00%+1113F-HRTimelineValue filed as zero, left out of ratios.