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Stonepine Capital Management, LLC

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13F filer, CIK 1440771, Bend, OR

Stonepine Capital Management, LLC reported $101,927,543 across 59 holdings for the quarter ended 2025-06-30, in a 13F-HR filed 2025-08-13. Its ten largest share positions make up 59.23% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0000935836-25-000497

Period
2025-06-30
Reported value
$102M
Holdings
59
Top 10 weight
59.23%
New
21
Sold out
28

Largest buys vs the previous quarter

SecurityShares changeApprox. value
VSTMadded+747,386$3.1M
ACADadded+131,607$2.84M
ARDXnew+555,000$2.18M
ITEOS THERAPEUTICS INCadded+200,033$1.99M
NKTRnew+50,200$1.3M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
OPTINOSE INCexited-788,647-$7.23M
URGNexited-333,400-$3.69M
AQSTexited-200,000-$3.04M
ESTAreduced-67,500-$2.88M
LKFTexited-93,968-$2.36M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q2 2025

Share positions as resolved from 13F-HR 0000935836-25-000497, largest first. % of portfolio is the value over $101,512,543, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
ADMAADMA BIOLOGICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,870,000 shares; 2024Q4: 1,241,032 shares; 2025Q1: 810,000 shares; 2025Q2: 750,000 shares 750,000$13.7M13.45%-60,000Timeline
EOLSEVOLUS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,369,821 shares; 2024Q4: 1,264,651 shares; 2025Q1: 1,134,574 shares; 2025Q2: 916,500 shares 916,500$8.44M8.32%-218,074Timeline
ZVRAZEVRA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 700,000 shares; 2024Q4: 597,700 shares; 2025Q1: 650,000 shares; 2025Q2: 775,620 shares 775,620$6.83M6.73%+125,620Timeline
VSTMVERASTEM INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,310,287 shares; 2024Q4: 870,000 shares; 2025Q1: 613,000 shares; 2025Q2: 1,360,386 shares 1,360,386$5.65M5.56%+747,386Timeline
INDIVIOR PLCINDIVIOR PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 270,000 shares; 2024Q4: 305,000 shares; 2025Q1: 304,000 shares; 2025Q2: 350,000 shares 350,000$5.16M5.08%+46,000
ACADACADIA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 196,895 shares; 2024Q4: 220,000 shares; 2025Q1: 93,393 shares; 2025Q2: 225,000 shares 225,000$4.85M4.78%+131,607Timeline
ENTAENANTA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 331,900 shares; 2025Q1: 590,742 shares; 2025Q2: 604,066 shares 604,066$4.57M4.5%+13,324Timeline
TELATELA BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,110,000 shares; 2024Q4: 2,353,099 shares; 2025Q1: 2,055,225 shares; 2025Q2: 2,083,762 shares 2,083,762$4.04M3.98%+28,537Timeline
XOMAXOMA ROYALTY CORPORATIONQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 195,096 shares; 2024Q4: 125,700 shares; 2025Q1: 129,813 shares; 2025Q2: 152,143 shares 152,143$3.83M3.78%+22,330Timeline
ITEOS THERAPEUTICS INCITEOS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 30,000 shares; 2024Q4: 110,000 shares; 2025Q1: 110,000 shares; 2025Q2: 310,033 shares 310,033$3.09M3.04%+200,033
DAWNDAY ONE BIOPHARMACEUTICALS IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 205,675 shares; 2024Q4: 235,000 shares; 2025Q1: 348,820 shares; 2025Q2: 450,000 shares 450,000$2.92M2.88%+101,180Timeline
SRZNSURROZEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 110,000 shares; 2024Q4: 137,200 shares; 2025Q1: 285,782 shares; 2025Q2: 306,029 shares 306,029$2.74M2.7%+20,247Timeline
ANIPANI PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 20,400 shares; 2025Q1: 48,000 shares; 2025Q2: 38,597 shares 38,597$2.52M2.48%-9,403Timeline
ARDXARDELYX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 555,000 shares 555,000$2.18M2.14%newTimeline
ANIKANIKA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 189,308 shares; 2024Q4: 238,222 shares; 2025Q1: 206,639 shares; 2025Q2: 190,590 shares 190,590$2.02M1.99%-16,049Timeline
AYTUAYTU BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 500,958 shares; 2024Q4: 407,549 shares; 2025Q1: 463,721 shares; 2025Q2: 812,676 shares 812,676$1.77M1.75%+348,955Timeline
IKTINHIBIKASE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 1,132,388 shares; 2025Q1: 914,973 shares; 2025Q2: 733,793 shares 733,793$1.43M1.41%-181,180Timeline
GERNGERON CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 500,000 shares; 2025Q2: 1,000,000 shares 1,000,000$1.41M1.39%+500,000Timeline
HRTXHERON THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 700,000 shares; 2025Q1: 796,100 shares; 2025Q2: 657,380 shares 657,380$1.36M1.34%-138,720Timeline
NKTRNEKTAR THERAPEUTICSQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 50,200 shares 50,200$1.3M1.28%newTimeline
Y-mAbs Therapeutics IncY-mAbs Therapeutics IncQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 131,160 shares; 2025Q2: 285,300 shares 285,300$1.29M1.27%+154,140
COLLCOLLEGIUM PHARMACEUTICAL INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 20,607 shares; 2025Q2: 41,500 shares 41,500$1.23M1.21%+20,893Timeline
VNDAVANDA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 25,000 shares; 2025Q1: 35,148 shares; 2025Q2: 250,000 shares 250,000$1.18M1.16%+214,852Timeline
KALVKALVISTA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 21,550 shares; 2025Q2: 100,000 shares 100,000$1.13M1.11%+78,450Timeline
ALMSALUMIS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 349,615 shares 349,615$1.05M1.03%newTimeline
MYOMYOMO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 100,000 shares; 2024Q4: 274,426 shares; 2025Q1: 276,707 shares; 2025Q2: 457,419 shares 457,419$988K0.97%+180,712Timeline
RZLTREZOLUTE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 219,000 shares 219,000$977K0.96%newTimeline
XERSXERIS BIOPHARMA HOLDINGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 182,317 shares; 2025Q1: 102,265 shares; 2025Q2: 205,100 shares 205,100$958K0.94%+102,835Timeline
PMVPPMV PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 535,805 shares; 2025Q1: 630,183 shares; 2025Q2: 845,968 shares 845,968$897K0.88%+215,785Timeline
SNDXSYNDAX PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 92,900 shares 92,900$870K0.86%newTimeline
GRCEGRACE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 294,550 shares; 2025Q2: 292,500 shares 292,500$869K0.86%-2,050Timeline
KZRKEZAR LIFE SCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 110,000 shares; 2025Q1: 100,000 shares; 2025Q2: 169,859 shares 169,859$778K0.77%+69,859Timeline
ANGOANGIODYNAMICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 77,141 shares 77,141$765K0.75%newTimeline
ACHVACHIEVE LIFE SCIENCE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 333,333 shares 333,333$753K0.74%newTimeline
ACRSACLARIS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,458,873 shares; 2024Q4: 663,405 shares; 2025Q1: 527,842 shares; 2025Q2: 491,300 shares 491,300$698K0.69%-36,542Timeline
VIRVIR BIOTECHNOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 164,106 shares; 2025Q1: 144,628 shares; 2025Q2: 130,000 shares 130,000$655K0.65%-14,628Timeline
BIOABIOAGE LABS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 50,000 shares; 2025Q2: 151,085 shares 151,085$624K0.61%+101,085Timeline
LQDALIQUIDIA CORPORATIONQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 50,000 shares 50,000$623K0.61%newTimeline
ANTXAN2 THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 196,732 shares; 2025Q1: not reported; 2025Q2: 544,494 shares 544,494$577K0.57%newTimeline
KPRXKIORA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 202,400 shares; 2024Q4: 200,970 shares; 2025Q1: 200,647 shares; 2025Q2: 178,000 shares 178,000$513K0.51%-22,647Timeline
SPROSPERO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 156,888 shares 156,888$455K0.45%newTimeline
HILLEVAX INCHILLEVAX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 132,347 shares; 2025Q1: 238,950 shares; 2025Q2: 226,009 shares 226,009$450K0.44%-12,941
THERATECHNOLOGIES INCTHERATECHNOLOGIES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 25,825 shares; 2025Q2: 189,051 shares 189,051$446K0.44%+163,226
LUNGPULMONX CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 145,900 shares 145,900$378K0.37%newTimeline
HCATHEALTH CATALYST INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 100,000 shares 100,000$377K0.37%newTimeline
ESTAESTABLISHMENT LABS HLDGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 75,000 shares; 2024Q4: 80,002 shares; 2025Q1: 74,500 shares; 2025Q2: 7,000 shares 7,000$299K0.29%-67,500Timeline
DVAXDYNAVAX TECHNOLOGIES CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 30,000 shares 30,000$298K0.29%newTimeline
ABEOABEONA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 45,000 shares 45,000$256K0.25%newTimeline
SVRASAVARA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 29,079 shares; 2025Q2: 85,000 shares 85,000$194K0.19%+55,921Timeline
INABIN8BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 82,430 shares 82,430$172K0.17%newTimeline
NUVBNUVATION BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 85,300 shares 85,300$166K0.16%newTimeline
KURAKURA ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 25,000 shares 25,000$144K0.14%newTimeline
CLYMCLIMB BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 116,147 shares 116,147$144K0.14%newTimeline
CALCCALCIMEDICA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 468,793 shares; 2025Q1: 367,371 shares; 2025Q2: 85,000 shares 85,000$136K0.13%-282,371Timeline
GLUEMONTE ROSA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 30,000 shares 30,000$135K0.13%newTimeline
ZNTLZENTALIS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 60,000 shares; 2025Q2: 109,010 shares 109,010$126K0.12%+49,010Timeline
BOLDBOUNDLESS BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 106,175 shares 106,175$107K0.11%newTimeline
CHRSCOHERUS ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 250,000 shares; 2025Q1: 620,588 shares; 2025Q2: 62,700 shares 62,700$45.9K0.05%-557,888Timeline

Options

Puts and calls, as filed. The amount and value describe the underlying shares, not the option premium, so they stay out of % of portfolio (H5).

SecurityTypeAmountValueChange
VSTMVERASTEM INC COMMON STOCKcall100,000$415Knew

Sold out in Q2 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
OPTINOSE INCOPTINOSE INC788,647$7.23Mshares
URGNUROGEN PHARMA LTD333,400$3.69Mshares
AQSTAQUESTIVE THERAPEUTICS INC200,000$3.04Mshares
LKFTLAKEFRONT BIOTHERAPEUTICS NV93,968$2.36Mshares
EDSAEDESA BIOTECH INC687,500$1.68Mshares
KROSKEROS THERAPEUTICS INC100,000$1.02Mshares
SCPHARMACEUTICALS INCSCPHARMACEUTICALS INC347,687$914Kshares
INOINOVIO PHARMACEUTICALS INC518,331$845Kshares
PROFPROFOUND MED CORP139,942$814Kshares
THRDTHIRD HARMONIC BIO INC212,783$738Kshares
ACELYRIN INCACELYRIN INC167,580$414Kshares
NBPNOVABRIDGE BIOSCIENCES483,647$398Kshares
SEPNSEPTERNA INC68,084$394Kshares
XGNEXAGEN INC95,747$344Kshares
RNXTRENOVORX INC278,188$275Kshares
ADICET BIO INCADICET BIO INC508,266$204Kshares
CARGO THERAPEUTICS INC COMCARGO THERAPEUTICS INC COM50,000$204Kshares
MISTMILESTONE PHARMACEUTICALS IN250,000$200Kshares
CRBPCORBUS PHARMACEUTICALS HLDGS35,000$186Kshares
PYPDPOLYPID LTD54,975$149Kshares
ELANELANCO ANIMAL HEALTH INC10,000$105Kshares
AMARIN CORP PLCAMARIN CORP PLC651,614$105Kshares
WHWKWHITEHAWK THERAPEUTICS INC46,698$83.1Kshares
IOVAIOVANCE BIOTHERAPEUTICS INC20,000$66.6Kshares
EBSEMERGENT BIOSOLUTIONS INC5,000$24.3Kshares
NKTXNKARTA INC10,000$18.4Kshares
ESPRESPERION THERAPEUTICS INC NE10,000$14.4Kshares
APREAPREA THERAPEUTICS INC102,242$14.4Kshares

How Q2 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0000935836-25-000497 base2025-08-13acceptance time not in the bulk data set