Skip to content
Disclosery

TYRA TYRA BIOSCIENCES INC

Follow

COMMON STOCK (common), issuer CIK 1863127

112 managers (115 13F filers) reported a position in TYRA shares at 2024-12-31, 48,613,629 shares in all. 27 filers opened a position and 18 filers sold out during the quarter.

Managers
112
13F filers
115
New
27
Added
34
Reduced
25
Sold out
18
Shares held by filers
48,613,629

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2024

Filers in the available 13F reports with a share position at 2024-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.10,637,290$148M1.97%+220,68113F-HRTimelineGroup
Canaan Partners XI LLC4,179,857$58.1M75.17%-230,13413F-HRTimeline
Alta Partners Management Company, L.P.4,080,296$56.7M89.47%13F-HRTimeline
Nextech Invest Ltd.4,055,861$56.4M9.15%013F-HRTimeline
BVF INC/ILin group BVF INC/IL3,944,194$54.8M1.86%-717,00013F-HRTimelineGroup
FMR LLCin group FMR LLC3,107,970$43.2M<0.01%-264,88013F-HRTimelineGroup
Boxer Capital Management, LLCin group Boxer Capital Management, LLC2,027,678$28.2M2.4%13F-HRTimelineGroup
TCG Crossover Management, LLC1,989,103$27.6M2.7%013F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson1,746,320$24.3M0.01%+679,12413F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.1,718,504$23.9M<0.01%+202,33213F-HRTimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC1,470,086$20.4M0.42%+701,44813F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC1,207,765$16.8M<0.01%-37,64313F-HRTimelineGroup
FARALLON CAPITAL MANAGEMENT, L.L.C.1,000,981$13.9M0.07%new13F-HRTimeline
Vestal Point Capital, LP990,000$13.8M0.82%new13F-HRTimeline
5AM Venture Management, LLC939,298$13.1M3.12%013F-HRTimeline
Kynam Capital Management, LP530,478$7.37M0.49%+62,53113F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC517,578$7.2M<0.01%-5,61213F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP407,573$5.67M<0.01%+22,84113F-HRTimelineGroup
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…354,012$4.92M0.01%new13F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC315,141$4.38M<0.01%+304,63713F-HRTimelineGroup
JACOBS LEVY EQUITY MANAGEMENT, INC244,245$3.4M0.01%new13F-HRTimeline
Sio Capital Management, LLC240,870$3.35M0.94%-160,00013F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP222,764$3.1M<0.01%+8,41113F-HRTimelineGroup
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…200,000$2.78M<0.01%013F-HRTimelineGroup
Ally Bridge Group (NY) LLC175,063$2.43M2.09%-95,01213F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co170,600$2.37M<0.01%-3,13713F-HRTimelineGroup
Polar Asset Management Partners Inc.111,107$1.54M0.02%+23,00713F-HR/ATimeline
Cubist Systematic Strategies, LLC109,748$1.53M0.02%new13F-HRTimeline
Nantahala Capital Management, LLCin group Nantahala Capital Management,…100,000$1.39M0.1%new13F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…94,859$1.32M<0.01%+4,03413F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO91,115$1.27M<0.01%-277,53213F-HRTimelineGroup
INVESTMENT COUNSEL CO OF NEVADA85,020$1.18M3%13F-HRTimeline
UBS Group AGgroup of 2 filers holding83,486$1.16M+47,313Timeline
OPPENHEIMER & CO INCin group OPPENHEIMER ASSET MANAGEMENT …75,439$1.05M0.02%-1,36713F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY74,149$1.03M<0.01%+5,23313F-HR/ATimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/66,157$920K<0.01%+11,80413F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD65,039$904K<0.01%+29,47313F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC64,110$891K<0.01%-24,97113F-HRTimelineGroup
Walleye Capital LLCin group Walleye Capital LLC62,980$875K0.01%-63,61713F-HRTimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC60,000$834K0.24%new13F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding58,569$814K+19,393Timeline
VICTORY CAPITAL MANAGEMENT INC56,640$787K<0.01%+26,56013F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC55,587$773K<0.01%+31,63513F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC54,783$761K<0.01%13F-HR/ATimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP54,077$752K<0.01%+34,46313F-HRTimelineGroup
Nuveen Asset Management, LLCin group TIAA49,998$695K<0.01%013F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp45,007$626K<0.01%+2,22113F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC43,070$599K<0.01%+5,44513F-HR/ATimelineGroup
SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLCin group SUSQUEHANNA INTERNATIONAL GRO…39,093$543K0.01%13F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP37,981$528K<0.01%+28,07413F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC29,100$404K<0.01%new13F-HRTimeline
RHUMBLINE ADVISERS26,202$364K<0.01%+1,02713F-HR/ATimeline
HighVista Strategies LLC23,941$333K0.12%+7,86313F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC22,142$308K<0.01%-20,85713F-HRTimelineGroup
Auour Investments LLC21,020$304K0.11%013F-HRTimeline
Swiss National Bank20,700$288K<0.01%-5,00013F-HRTimeline
PDT Partners, LLC20,359$283K0.03%new13F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\18,909$263K<0.01%+6,46613F-HR/ATimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC18,216$253K<0.01%new13F-HRTimelineGroup
EntryPoint Capital, LLC18,209$253K0.11%new13F-HRTimeline
ALLIANCEBERNSTEIN L.P.17,570$244K<0.01%013F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC17,560$244K0.01%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC16,803$234K<0.01%+2,13613F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL15,577$217K<0.01%-10,76913F-HRTimeline
Jump Financial, LLCin group Jump Financial, LLC15,160$211K<0.01%new13F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …13,368$186K<0.01%-81613F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding13,327$186K+2,218Timeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.12,783$178K<0.01%new13F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources12,751$177K<0.01%+10413F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…12,207$170K<0.01%013F-HRTimelineGroup
China Universal Asset Management Co., L…10,730$149K0.01%new13F-HRTimeline
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP10,607$147K<0.01%013F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…10,570$147K<0.01%-2,36613F-HR/ATimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…10,455$145K<0.01%+10,44713F-HRTimelineGroup
Corebridge Financial, Inc.in group Corebridge Financial, Inc.10,102$140K<0.01%-76213F-HRTimelineGroup
SG Americas Securities, LLC9,671$134K<0.01%-3,54013F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN9,493$132K<0.01%+3,23613F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc9,340$130K<0.01%013F-HRTimelineGroup
EXCHANGE TRADED CONCEPTS, LLC8,311$116K<0.01%013F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND7,423$103K<0.01%013F-HR/ATimeline
Police & Firemen's Retirement System of…5,049$70.2K<0.01%13F-HRTimeline
AlphaQuest LLC5,023$69.8K0.01%-15,85513F-HRTimeline
VIRTUS ADVISERS, LLCin group Virtus Investment Advisers, L…4,686$65.1K0.03%+4413F-HRTimelineGroup
Aquatic Capital Management LLC4,586$63.7K<0.01%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS4,318$60K<0.01%new13F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\3,612$50.2K<0.01%new13F-HRTimelineGroup
KLP KAPITALFORVALTNING AS2,200$30.6K<0.01%13F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…1,991$27.7K<0.01%013F-HRTimelineGroup
R Squared Ltd1,480$20.6K0.02%13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,417$19.7K<0.01%+20613F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.1,063$14.8K<0.01%13F-HRTimeline
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.1,028$14.3K<0.01%+9813F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA774$11K<0.01%-1,36113F-HRTimelineGroup
STRS OHIO700$9.73K<0.01%013F-HRTimeline
Point72 (DIFC) Ltd561$7.79K<0.01%new13F-HRTimeline
AMALGAMATED BANK424$6K<0.01%013F-HRTimeline
Aster Capital Management (DIFC) Ltd214$2.98K<0.01%new13F-HRTimeline
CWM, LLCin group CWM, LLC71$1K<0.01%+4913F-HRTimelineGroup
Creative Planningin group Creative Planning63$876<0.01%new13F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…58$806<0.01%013F-HRTimelineGroup
GAMMA Investing LLC26$361<0.01%-5713F-HRTimeline
SIGNATUREFD, LLC24$334<0.01%new13F-HRTimeline
NISA INVESTMENT ADVISORS, LLC23$320<0.01%-1713F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.22$306<0.01%-18313F-HR/ATimelineGroup
Sterling Capital Management LLC21$292<0.01%013F-HRTimeline
SBI Securities Co., Ltd.19$264<0.01%13F-HRTimeline
CoreCap Advisors, LLC16$222<0.01%new13F-HRTimeline
ROTHSCHILD INVESTMENT LLC5$70<0.01%-1013F-HRTimeline
IFP Advisors, Inc2$28<0.01%new13F-HRTimeline
Covestor Ltd6$00%013F-HRTimelineValue filed as zero, left out of ratios.
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$00%013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.
NOMURA ASSET MANAGEMENT CO LTDin group NOMURA ASSET MANAGEMENT CO LTD0$00%new13F-HRTimelineGroupValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.