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Disclosery

SPRY ARS PHARMACEUTICALS INC

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COM (common), issuer CIK 1671858

185 managers (188 13F filers) reported a position in SPRY shares at 2025-09-30, 83,632,752 shares in all. 42 filers opened a position and 43 filers sold out during the quarter.

Managers
185
13F filers
188
New
42
Added
69
Reduced
44
Sold out
43
Shares held by filers
83,632,752

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.10,860,977$109M1.34%013F-HRTimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC8,288,510$83.3M2%013F-HRTimelineGroup
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…7,503,812$75.4M1.16%-2,220,69613F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.4,831,327$48.6M<0.01%+407,86313F-HRTimelineGroup
Rubric Capital Management LP4,500,000$45.2M0.61%+3,205,12213F-HRTimeline
SR One Capital Management, LP4,012,903$40.3M5.83%013F-HRTimeline
VANGUARD GROUP INCin group VANGUARD GROUP INC3,500,303$35.2M<0.01%+237,63013F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc3,097,022$31.1M0.05%+1,594,44713F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP2,895,256$29.1M<0.01%+700,76313F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.2,642,111$26.6M0.01%-1,183,68213F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources2,398,012$24.1M0.01%+569,25713F-HRTimelineGroup
Casdin Capital, LLC1,600,000$16.1M1.34%new13F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC1,586,033$15.9M0.01%-656,14313F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,505,617$15.1M<0.01%+163,23013F-HRTimelineGroup
Southpoint Capital Advisors LPin group Southpoint Capital Advisors LP1,500,000$15.1M0.4%-209,06913F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC1,325,739$13.3M<0.01%-138,57313F-HRTimelineGroup
MPM BIOIMPACT LLC1,303,399$13.1M2.14%013F-HRTimeline
BAMCO INC /NY/in group Baron Capital1,268,532$12.7M0.03%+1,228,53213F-HRTimelineGroup
Janney Montgomery Scott LLC1,213,020$12.2M0.03%+621,59513F-HRTimeline
Qube Research & Technologies Ltd1,034,798$10.4M0.01%new13F-HRTimeline
UBS Group AGgroup of 2 filers holding995,034$10M-197,546Timeline
Eversept Partners, LP976,511$9.81M0.75%new13F-HRTimeline
LEVIN CAPITAL STRATEGIES, L.P.764,294$7.68M0.7%+475,14713F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC756,347$7.6M<0.01%+82,97713F-HRTimelineGroup
FMR LLCin group FMR LLC742,508$7.46M<0.01%-824,50213F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY700,414$7.04M<0.01%+316,79813F-HR/ATimelineGroup
Nextech Invest Ltd.660,703$6.64M1.01%-81,02613F-HRTimeline
Trexquant Investment LP631,720$6.35M0.07%new13F-HRTimeline
K2 PRINCIPAL FUND, L.P.621,807$6.25M0.66%+304,68113F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP531,503$5.34M<0.01%+46,48913F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co520,758$5.23M<0.01%+78,55613F-HRTimelineGroup
CenterBook Partners LP512,367$5.15M0.25%new13F-HRTimeline
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.390,092$3.92M0.01%+100,00013F-HRTimelineGroup
Empire Life Investments Inc.355,686$3.57M0.21%new13F-HRTimeline
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP352,943$3.55M<0.01%+12,82413F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/272,026$2.73M<0.01%-53,32613F-HR/ATimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management246,170$2.47M<0.01%-82,90313F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC242,037$2.43M<0.01%new13F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC228,569$2.3M<0.01%-393,66613F-HR/ATimelineGroup
Lisanti Capital Growth, LLC211,189$2.12M0.52%-208,88613F-HRTimeline
FAS Wealth Partners, Inc.200,620$2.02M0.14%+51,46013F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC199,153$2M<0.01%new13F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP197,320$1.98M<0.01%+157,40613F-HRTimelineGroup
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…186,726$1.82M<0.01%-48,11513F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP178,148$1.79M<0.01%-2,34413F-HRTimelineGroup
WEXFORD CAPITAL LP168,238$1.69M0.51%-214,31713F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp154,604$1.55M<0.01%+9,48713F-HRTimelineGroup
Freestone Grove Partners LP152,197$1.53M0.01%new13F-HRTimeline
Woodline Partners LP150,936$1.52M0.01%-149,48313F-HRTimeline
Nuveen, LLCin group TIAA149,597$1.5M<0.01%+10,46413F-HRTimelineGroup
HUSSMAN STRATEGIC ADVISORS, INC.147,000$1.48M0.32%+42,00013F-HRTimeline
Steward Partners Investment Advisory, L…146,692$1.47M0.01%+18,51213F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd143,636$1.44M0.07%+126,54313F-HRTimelineGroup
DAFNA Capital Management LLC140,500$1.41M0.35%new13F-HRTimeline
Knights of Columbus Asset Advisors LLC134,476$1.35M0.08%+66,38213F-HRTimeline
Quinn Opportunity Partners LLC125,000$1.26M0.09%+80,00013F-HRTimeline
Rafferty Asset Management, LLC122,410$1.23M<0.01%+41,56413F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC114,853$1.15M<0.01%-51,33113F-HRTimelineGroup
Aquatic Capital Management LLC105,751$1.06M0.02%+57,06313F-HRTimeline
Coastal Bridge Advisors, LLC91,675$921K0.07%+4,65013F-HRTimeline
Epoch Investment Partners, Inc.89,980$904K<0.01%+17,20013F-HRTimeline
Cambridge Investment Research Advisors,…87,161$876K<0.01%-113F-HRTimeline
Swiss National Bank84,300$847K<0.01%013F-HRTimeline
VALLEY FORGE INVESTMENT CONSULTANTS INC…83,225$836K0.24%013F-HRTimeline
SECTORAL ASSET MANAGEMENT INC81,785$822K0.51%+16,00013F-HRTimeline
RHUMBLINE ADVISERS81,204$816K<0.01%-5713F-HRTimeline
Sculptor Capital LPin group Sculptor Capital LP77,100$775K0.01%new13F-HRTimelineGroup
PRINCIPAL FINANCIAL GROUP INCgroup of 2 filers holding76,901$773K+21,438Timeline
SIT INVESTMENT ASSOCIATES INCin group SIT INVESTMENT ASSOCIATES INC74,525$749K0.02%+34,17513F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN73,842$742K<0.01%+12,73613F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding72,177$725K+30,977Timeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…67,212$675K0.01%new13F-HRTimelineGroup
CastleKnight Management LP65,300$656K0.04%013F-HRTimeline
Campbell & CO Investment Adviser LLC60,525$608K0.05%new13F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC59,230$595K0.06%new13F-HRTimelineGroup
Matisse Capital57,791$581K0.26%+1,07713F-HRTimeline
AssuredPartners Investment Advisors, LLC57,785$581K0.13%+81613F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc55,243$555K<0.01%+41813F-HRTimelineGroup
AMERICAN ASSETS INCin group American Assets Investment Ma…55,000$553K0.18%new13F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD53,402$537K<0.01%+35,84513F-HRTimeline
Permanent Capital Management, LP53,341$536K0.1%13F-HRTimeline
DARK FOREST CAPITAL MANAGEMENT LP50,940$512K0.02%new13F-HR/ATimeline
ALPS ADVISORS INCin group ALPS ADVISORS INC49,600$498K<0.01%-3,40013F-HRTimelineGroup
Kestra Advisory Services, LLCin group Kestra Advisory Services, LLC49,199$494K<0.01%+15,43913F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO48,112$484K<0.01%-36,97013F-HRTimelineGroup
AlphaQuest LLC45,819$460K0.03%+22,28313F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…44,388$446K<0.01%+7,40013F-HRTimeline
DIKER MANAGEMENT LLCin group DIKER MANAGEMENT LLC43,508$437K0.35%+2,50813F-HRTimelineGroup
SCHULHOFF & CO INC43,500$437K0.19%013F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\41,951$422K<0.01%+4,93813F-HRTimelineGroup
Quantinno Capital Management LP40,472$407K<0.01%new13F-HRTimeline
Invesco Ltd.in group Invesco Ltd.40,109$403K<0.01%-77,39113F-HRTimelineGroup
Legato Capital Management LLC39,410$396K0.04%-64,72313F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA38,116$383K<0.01%-64,67513F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding37,483$375K-305Timeline
Walleye Capital LLCin group Walleye Capital LLC36,862$370K<0.01%new13F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC35,856$360K<0.01%new13F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO35,059$352K<0.01%+49913F-HR/ATimelineGroup
DRW Securities, LLC35,742$349K0.02%new13F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…34,338$345K<0.01%+1,56113F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.34,219$344K<0.01%-23,23013F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/33,788$340K<0.01%+6,39713F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …32,473$326K<0.01%-1,54713F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC31,514$317K<0.01%+5,55113F-HRTimeline
Cresset Asset Management, LLC30,152$303K<0.01%013F-HR/ATimeline
Caption Management, LLC29,812$300K0.02%new13F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC27,600$277K<0.01%new13F-HRTimelineGroup
Creative Planningin group Creative Planning27,175$273K<0.01%-10,42913F-HRTimelineGroup
PROFUND ADVISORS LLC26,330$265K0.01%+9,24213F-HRTimeline
HighTower Advisors, LLC26,330$265K<0.01%+22013F-HRTimeline
Allianz Asset Management GmbHin group Allianz SE26,000$261K<0.01%-10,60013F-HRTimelineGroup
LETKO, BROSSEAU & ASSOCIATES INC24,700$248K<0.01%013F-HRTimeline
WOLVERINE TRADING, LLC24,266$236K<0.01%new13F-HRTimeline
LPL Financial LLC23,084$232K<0.01%-2,81713F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson21,600$217K<0.01%-47,87913F-HRTimelineGroup
Private Advisor Group, LLC20,582$207K<0.01%new13F-HRTimeline
Everstar Asset Management, LLC20,000$201K0.11%+5,00013F-HRTimeline
Belpointe Asset Management LLC18,860$190K0.01%+1,53713F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND17,707$178K<0.01%-75,59113F-HRTimeline
China Universal Asset Management Co., L…17,323$174K0.01%-2,40313F-HRTimeline
Police & Firemen's Retirement System of…15,148$152K<0.01%+3,16013F-HRTimeline
FOSTER & MOTLEY INC14,780$149K0.01%013F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding14,370$144K-242,596Timeline
AMICA MUTUAL INSURANCE CO14,350$144K0.01%013F-HRTimeline
ProShare Advisors LLC13,607$137K<0.01%-1,30313F-HRTimeline
American Capital Advisory, LLC13,570$136K0.06%+15713F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM13,073$131K<0.01%+20413F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS12,531$126K<0.01%+6,43413F-HRTimelineGroup
OPPENHEIMER & CO INCin group OPPENHEIMER ASSET MANAGEMENT …12,514$126K<0.01%013F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…11,662$117K<0.01%+4,24313F-HRTimeline
KLP KAPITALFORVALTNING AS11,600$117K<0.01%013F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS10,825$109K<0.01%-1,04113F-HRTimeline
SG Americas Securities, LLC10,105$102K<0.01%-15,19613F-HRTimeline
CX Institutional9,190$92K<0.01%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC8,619$86.6K<0.01%-28,96413F-HRTimelineGroup
Quantbot Technologies LP8,126$81.7K<0.01%new13F-HRTimeline
GROUP ONE TRADING LLC7,698$77.4K<0.01%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…7,453$74.9K<0.01%+1,16913F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…6,668$67K<0.01%+4,42713F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC6,253$62.8K<0.01%-2813F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…5,598$56.3K<0.01%013F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.4,128$42.8K<0.01%-1,08713F-HRTimelineGroup
SIGNATUREFD, LLC2,812$28.3K<0.01%013F-HRTimeline
CWM, LLCin group CWM, LLC2,547$26K<0.01%+1,80613F-HRTimelineGroup
Bernard Wealth Management Corp.2,520$25.3K0.01%013F-HRTimeline
Affinity Asset Advisors, LLC2,500$25.1K<0.01%new13F-HRTimeline
Future Financial Wealth Managment LLC2,200$22.1K0.01%+1,20013F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
TD Waterhouse Canada Inc.2,160$21.8K<0.01%013F-HRTimeline
GF FUND MANAGEMENT CO. LTD.2,126$21.4K<0.01%-36213F-HRTimeline
CAZ INVESTMENTS LPin group CAZ INVESTMENTS LP2,000$20.1K0.04%013F-HRTimelineGroup
PARK CIRCLE Co2,000$20.1K0.02%013F-HRTimeline
AMALGAMATED BANK1,682$17K<0.01%013F-HRTimeline
Caitong International Asset Management …1,687$17K0.01%new13F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\1,575$15.8K<0.01%+64913F-HRTimelineGroup
Farther Finance Advisors, LLC1,540$15.5K<0.01%+1,04713F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP1,460$14.3K<0.01%+12513F-HRTimelineGroup
Versant Capital Management, Inc1,343$13.5K<0.01%+72113F-HRTimeline
Capital Analysts, LLCin group Capital Analysts, LLC1,300$13K<0.01%013F-HRTimelineGroup
Heritage Wealth Advisors1,000$10.1K<0.01%013F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…1,000$10.1K<0.01%new13F-HRTimelineGroup
Allworth Financial LP796$8K<0.01%+4413F-HRTimeline
SBI Securities Co., Ltd.698$7.01K<0.01%+4813F-HRTimeline
Smartleaf Asset Management LLC552$5.37K<0.01%new13F-HRTimeline
Avion Wealth500$5K<0.01%013F-HRTimeline
Golden State Wealth Management, LLC484$4.86K<0.01%new13F-HRTimeline
Tripletail Wealth Management, LLC450$4.66K0.01%new13F-HRTimeline
BROWN, LISLE/CUMMINGS, INC.400$4.02K<0.01%013F-HRTimeline
Spire Wealth Managementin group Spire Wealth Management400$4.02K<0.01%013F-HRTimelineGroup
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.367$4K<0.01%013F-HRTimelineGroup
Optiver Holding B.V.in group Optiver Holding B.V.356$3.58K<0.01%new13F-HRTimelineGroup
QUADRANT CAPITAL GROUP LLC347$3.49K<0.01%new13F-HRTimeline
Amica Retiree Medical Trust346$3K<0.01%013F-HRTimeline
BESSEMER GROUP INCin group BESSEMER GROUP INC235$2K<0.01%013F-HRTimelineGroup
GAMMA Investing LLC179$1.8K<0.01%-11613F-HRTimeline
Tidemark, LLC169$1.7K<0.01%-1,50013F-HRTimeline
Sterling Capital Management LLC143$1.44K<0.01%+1013F-HRTimeline
Arax Advisory Partners128$1.29K<0.01%new13F-HRTimeline
COMERICA BANK118$1.19K<0.01%new13F-HRTimeline
JPL Wealth Management, LLC55$553<0.01%new13F-HRTimeline
Parkside Financial Bank & Trust45$453<0.01%013F-HRTimeline
ROTHSCHILD INVESTMENT LLC35$352<0.01%-13013F-HRTimeline
Advisory Services Network, LLC27$271<0.01%new13F-HRTimeline
Larson Financial Group LLC4$40<0.01%-2813F-HRTimeline
LANARK FINANCIAL, INC.1$10<0.01%new13F-HRTimeline
Covestor Ltd8$00%013F-HRTimelineValue filed as zero, left out of ratios.