Skip to content
Disclosery

SPRY ARS PHARMACEUTICALS INC

Follow

COM (common), issuer CIK 1671858

190 managers (192 13F filers) reported a position in SPRY shares at 2025-12-31, 90,158,236 shares in all. 31 filers opened a position and 33 filers sold out during the quarter.

Managers
190
13F filers
192
New
31
Added
58
Reduced
55
Sold out
33
Shares held by filers
90,158,236

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.10,860,977$127M1.3%013F-HRTimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC8,288,510$96.6M1.98%013F-HRTimelineGroup
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…7,503,812$87.4M1.12%013F-HRTimelineGroup
Rubric Capital Management LP6,200,000$72.2M0.86%+1,700,00013F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.5,085,317$59.2M<0.01%+253,99013F-HRTimelineGroup
SR One Capital Management, LP4,012,903$46.8M6.62%013F-HRTimeline
Aberdeen Group plcin group Aberdeen Group plc3,556,049$41.4M0.06%+459,02713F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC3,509,174$40.9M<0.01%+8,87113F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP3,223,581$37.6M<0.01%+328,32513F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC3,168,406$36.9M0.03%new13F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources2,543,097$29.6M0.01%+145,08513F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding2,515,311$29.3M+1,520,277Timeline
Tyro Capital Management LLC1,994,852$23.2M7.23%new13F-HR/ATimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC1,954,472$22.8M0.02%+368,43913F-HRTimelineGroup
Casdin Capital, LLC1,600,000$18.6M1.16%013F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,552,870$18.1M<0.01%+47,25313F-HRTimelineGroup
Southpoint Capital Advisors LPin group Southpoint Capital Advisors LP1,500,000$17.5M0.41%013F-HRTimelineGroup
Janney Montgomery Scott LLC1,287,832$15M0.03%+74,81213F-HRTimeline
BAMCO INC /NY/in group Baron Capital1,268,532$14.8M0.04%013F-HRTimelineGroup
Pavaki Capital Management LLC1,172,000$13.7M9.53%13F-HR/ATimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC812,036$9.46M<0.01%-513,70313F-HR/ATimelineGroup
FIL Ltdin group FIL Ltd810,073$9.44M0.01%new13F-HRTimelineGroup
LEVIN CAPITAL STRATEGIES, L.P.747,506$8.71M0.76%-16,78813F-HRTimeline
Nextech Invest Ltd.660,703$7.7M0.74%013F-HRTimeline
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/643,407$7.5M<0.01%new13F-HRTimelineGroup
CenterBook Partners LP568,361$6.62M0.32%+55,99413F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC566,056$6.59M<0.01%-190,29113F-HRTimelineGroup
GENERAL AMERICAN INVESTORS CO INC559,959$6.52M0.41%new13F-HRTimeline
Third Point LLC556,237$6.48M0.09%new13F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY552,364$6.44M<0.01%-148,05013F-HR/ATimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co550,932$6.42M<0.01%+30,17413F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP521,009$6.07M<0.01%-10,49413F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/482,084$5.62M<0.01%+210,05813F-HRTimelineGroup
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC455,766$5.31M<0.01%new13F-HRTimelineGroup
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.418,883$4.88M0.01%+28,79113F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO417,090$4.86M<0.01%+382,03113F-HRTimelineGroup
FMR LLCin group FMR LLC398,959$4.65M<0.01%-343,54913F-HRTimelineGroup
Lisanti Capital Growth, LLC396,509$4.62M1.09%+185,32013F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC369,569$4.31M0.32%+310,33913F-HR/ATimelineGroup
Empire Life Investments Inc.352,602$4.11M0.23%-3,08413F-HRTimeline
INVESTMENT MANAGEMENT ASSOCIATES INC /A…311,503$3.63M1.01%new13F-HRTimeline
Creek Drive Management Group LLC295,863$3.45M2.54%13F-HR/ATimeline
Eversept Partners, LP251,593$2.93M0.16%-724,91813F-HRTimeline
Steward Partners Investment Advisory, L…216,296$2.52M0.01%+69,60413F-HRTimeline
ROYCE & ASSOCIATES LP207,051$2.41M0.02%new13F-HRTimeline
FAS Wealth Partners, Inc.202,407$2.36M0.15%+1,78713F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC201,474$2.35M0.06%new13F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC196,387$2.29M<0.01%-32,18213F-HRTimelineGroup
DAFNA Capital Management LLC190,065$2.21M0.51%+49,56513F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP176,122$2.05M<0.01%-2,02613F-HRTimelineGroup
WEXFORD CAPITAL LP165,313$1.93M0.5%-2,92513F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp163,006$1.9M<0.01%+8,40213F-HRTimelineGroup
Quinn Opportunity Partners LLC155,000$1.81M0.08%+30,00013F-HRTimeline
Woodline Partners LP150,936$1.76M0.01%013F-HRTimeline
Trexquant Investment LP150,100$1.75M0.02%-481,62013F-HRTimeline
Nuveen, LLCin group TIAA149,597$1.74M<0.01%013F-HRTimelineGroup
Knights of Columbus Asset Advisors LLC130,729$1.52M0.09%-3,74713F-HRTimeline
Rafferty Asset Management, LLC115,564$1.35M<0.01%-6,84613F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCgroup of 2 filers holding112,766$1.31M+35,865Timeline
Legato Capital Management LLC109,095$1.27M0.11%+69,68513F-HRTimeline
Swiss National Bank107,200$1.25M<0.01%+22,90013F-HRTimeline
SIT INVESTMENT ASSOCIATES INCin group SIT INVESTMENT ASSOCIATES INC92,875$1.08M0.02%+18,35013F-HRTimelineGroup
Cambridge Investment Research Advisors,…87,161$1.01M<0.01%013F-HRTimeline
VALLEY FORGE INVESTMENT CONSULTANTS INC…83,225$970K0.28%013F-HRTimeline
ALPS ADVISORS INCin group ALPS ADVISORS INC81,168$946K0.01%+31,56813F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP79,214$923K<0.01%-118,10613F-HRTimelineGroup
SG Americas Securities, LLC76,203$888K<0.01%+66,09813F-HRTimeline
AssuredPartners Investment Advisors, LLC75,779$883K0.13%+17,99413F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO74,807$872K<0.01%+26,69513F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN74,256$865K<0.01%+41413F-HRTimelineGroup
RHUMBLINE ADVISERS73,293$854K<0.01%-7,91113F-HRTimeline
HRT FINANCIAL LP68,645$799K<0.01%new13F-HRTimeline
ALLIANCEBERNSTEIN L.P.60,120$700K<0.01%-2,581,99113F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc58,368$680K<0.01%+3,12513F-HRTimelineGroup
Matisse Capital55,561$647K0.29%-2,23013F-HRTimeline
AMERICAN ASSETS INCin group American Assets Investment Ma…55,000$641K0.2%013F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…54,098$630K<0.01%+9,71013F-HRTimeline
Coastal Bridge Advisors, LLC53,830$627K0.05%-37,84513F-HRTimeline
Quantinno Capital Management LP53,113$619K<0.01%+12,64113F-HRTimeline
Permanent Capital Management, LP52,306$609K0.12%-1,03513F-HRTimeline
SCHULHOFF & CO INC51,150$596K0.25%+7,65013F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\48,727$568K<0.01%+6,77613F-HRTimelineGroup
LOS ANGELES CAPITAL MANAGEMENT LLC65,746$567K<0.01%new13F-HRTimeline
PROFUND ADVISORS LLC42,808$499K0.02%+16,47813F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding38,903$453K+1,420Timeline
FOX RUN MANAGEMENT, L.L.C.38,587$450K0.07%new13F-HRTimeline
Invesco Ltd.in group Invesco Ltd.37,230$434K<0.01%-2,87913F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd37,201$433K0.01%-106,43513F-HRTimelineGroup
Aquatic Capital Management LLC36,037$420K0.01%-69,71413F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…34,338$400K<0.01%013F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC34,128$398K<0.01%-80,72513F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/33,788$394K<0.01%013F-HRTimeline
DIKER MANAGEMENT LLCin group DIKER MANAGEMENT LLC33,508$390K0.3%-10,00013F-HRTimelineGroup
AlphaQuest LLC32,970$384K0.02%-12,84913F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …32,058$373K<0.01%-41513F-HRTimelineGroup
Private Advisor Group, LLC31,460$367K<0.01%+10,87813F-HRTimeline
Cresset Asset Management, LLC30,152$351K<0.01%013F-HRTimeline
SECTORAL ASSET MANAGEMENT INC29,803$347K0.28%-51,98213F-HRTimeline
CANADA PENSION PLAN INVESTMENT BOARD29,600$345K<0.01%new13F-HRTimeline
Freestone Grove Partners LP28,003$326K<0.01%-124,19413F-HRTimeline
HighTower Advisors, LLC26,529$309K<0.01%+19913F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.26,527$309K<0.01%-7,69213F-HRTimelineGroup
Belpointe Asset Management LLC25,468$297K0.01%+6,60813F-HRTimeline
Creative Planningin group Creative Planning25,328$295K<0.01%-1,84713F-HRTimelineGroup
NANO CAP NEW MILLENNIUM GROWTH FUND L P25,000$291K0.25%13F-HRTimeline
LETKO, BROSSEAU & ASSOCIATES INC24,700$288K<0.01%013F-HRTimeline
Wealthspire Advisors, LLC23,650$276K<0.01%new13F-HRTimeline
LPL Financial LLC22,916$267K<0.01%-16813F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC22,626$264K<0.01%-8,88813F-HRTimeline
VARCOV Co.22,300$260K0.1%13F-HRTimeline
Empirical Financial Services, LLC d.b.a…21,614$252K<0.01%new13F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson21,600$252K<0.01%013F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC20,620$240K<0.01%+14,36713F-HRTimeline
Everstar Asset Management, LLC20,000$233K0.12%013F-HRTimeline
CITIGROUP INCin group CITIGROUP INC18,564$216K<0.01%+9,94513F-HRTimelineGroup
OPPENHEIMER & CO INCin group OPPENHEIMER ASSET MANAGEMENT …17,858$208K<0.01%+5,34413F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND17,707$206K<0.01%013F-HRTimeline
China Universal Asset Management Co., L…16,107$188K0.01%-1,21613F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM15,372$179K<0.01%+2,29913F-HRTimeline
Cetera Investment Advisers15,340$179K<0.01%new13F-HRTimeline
Police & Firemen's Retirement System of…15,148$176K<0.01%013F-HRTimeline
ProShare Advisors LLC15,139$176K<0.01%+1,53213F-HRTimeline
FOSTER & MOTLEY INC14,780$172K0.01%013F-HRTimeline
LAZARD ASSET MANAGEMENT LLCin group LAZARD ASSET MANAGEMENT LLC14,347$167K<0.01%new13F-HRTimelineGroup
AMICA MUTUAL INSURANCE CO14,350$167K0.01%013F-HRTimeline
SHERBROOKE PARK ADVISERS LLC13,139$153K0.4%new13F-HRTimeline
Tannin Capital LLC13,066$152K0.14%13F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP12,140$141K<0.01%+10,68013F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…11,662$136K<0.01%013F-HRTimeline
BLAIR WILLIAM & CO/IL11,600$135K<0.01%new13F-HRTimeline
KLP KAPITALFORVALTNING AS11,600$135K<0.01%013F-HRTimeline
Cygnus Capital Advisors, LLC10,556$123K0.09%13F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…10,362$121K<0.01%-176,36413F-HRTimelineGroup
K2 PRINCIPAL FUND, L.P.10,200$119K0.01%-611,60713F-HRTimeline
Wealth Architects, LLC10,000$116K0.01%new13F-HRTimeline
GROUP ONE TRADING LLC9,517$111K<0.01%+1,81913F-HRTimeline
CX Institutional8,990$105K<0.01%-20013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS6,407$74.6K<0.01%-6,12413F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…5,805$67.6K<0.01%-86313F-HRTimelineGroup
OSTERWEIS CAPITAL MANAGEMENT INCin group OSTERWEIS CAPITAL MANAGEMENT …5,610$65.4K<0.01%new13F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…4,888$56.9K<0.01%-71013F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA4,684$54K<0.01%-33,43213F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.3,626$42.2K<0.01%-50213F-HRTimelineGroup
Kestra Advisory Services, LLCin group Kestra Advisory Services, LLC3,470$40.4K<0.01%-45,72913F-HRTimelineGroup
SIGNATUREFD, LLC2,812$32.8K<0.01%013F-HRTimeline
Torren Management, LLC2,762$32.2K0.02%13F-HRTimeline
Versant Capital Management, Inc2,574$30K<0.01%+1,23113F-HRTimeline
Bernard Wealth Management Corp.2,520$29.4K0.01%013F-HRTimeline
TD Waterhouse Canada Inc.2,160$25.2K<0.01%013F-HRTimeline
CAZ INVESTMENTS LPin group CAZ INVESTMENTS LP2,000$23.3K0.04%013F-HRTimelineGroup
Smartleaf Asset Management LLC1,952$22.7K<0.01%+1,40013F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,942$22.6K<0.01%-18413F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…1,894$22.1K<0.01%+89413F-HR/ATimelineGroup
AMALGAMATED BANK1,853$22K<0.01%+17113F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\1,475$17.2K<0.01%-10013F-HRTimelineGroup
Capital Analysts, LLCin group Capital Analysts, LLC1,300$15K<0.01%013F-HR/ATimelineGroup
Farther Finance Advisors, LLC1,139$13.3K<0.01%-40113F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,049$12.2K<0.01%-6,40413F-HRTimelineGroup
Heritage Wealth Advisors1,000$11.7K<0.01%013F-HRTimeline
EASTERN BANK750$8.74K<0.01%new13F-HRTimeline
SBI Securities Co., Ltd.749$8.73K<0.01%+5113F-HRTimeline
Allworth Financial LP743$8.66K<0.01%-5313F-HRTimeline
Golden State Wealth Management, LLC484$5.64K<0.01%013F-HRTimeline
Avion Wealth500$5K<0.01%013F-HRTimeline
Sterling Capital Management LLC402$4.68K<0.01%+25913F-HRTimeline
BROWN, LISLE/CUMMINGS, INC.400$4.66K<0.01%013F-HRTimeline
Spire Wealth Managementin group Spire Wealth Management400$4.66K<0.01%013F-HRTimelineGroup
Arax Advisory Partners369$4.3K<0.01%+24113F-HRTimeline
Hilton Head Capital Partners, LLC365$4.25K<0.01%13F-HRTimeline
QUADRANT CAPITAL GROUP LLC347$4.04K<0.01%013F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.367$4K<0.01%013F-HRTimelineGroup
Optiver Holding B.V.in group Optiver Holding B.V.260$3.03K<0.01%-9613F-HRTimelineGroup
BESSEMER GROUP INCin group BESSEMER GROUP INC235$3K<0.01%013F-HRTimelineGroup
Quarry LP250$2.91K<0.01%new13F-HRTimeline
COMERICA BANK217$2.53K<0.01%+9913F-HRTimeline
Key Financial Inc200$2.33K<0.01%new13F-HRTimeline
Tidemark, LLC169$1.97K<0.01%013F-HRTimeline
Aster Capital Management (DIFC) Ltd153$1.78K<0.01%new13F-HRTimeline
GAMMA Investing LLC108$1.26K<0.01%-7113F-HRTimeline
Tripletail Wealth Management, LLC100$1.17K<0.01%-35013F-HRTimeline
CWM, LLCin group CWM, LLC62$1K<0.01%-2,48513F-HRTimelineGroup
Larson Financial Group LLC83$967<0.01%+7913F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…36$419<0.01%new13F-HRTimelineGroup
Strategic Wealth Partners, Ltd.20$233<0.01%new13F-HRTimeline
ROTHSCHILD INVESTMENT LLC16$186<0.01%-1913F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…9$105<0.01%new13F-HRTimelineGroup
Essential Partners LLC4$47<0.01%new13F-HRTimeline
LANARK FINANCIAL, INC.1$11<0.01%013F-HRTimeline
Covestor Ltd7$00%-113F-HRTimelineValue filed as zero, left out of ratios.
NOMURA ASSET MANAGEMENT CO LTDin group NOMURA ASSET MANAGEMENT CO LTD0$00%new13F-HRTimelineGroupValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.