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Disclosery

MAZE MAZE THERAPEUTICS INC

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Stock (common), issuer CIK 1842295

93 managers (94 13F filers) reported a position in MAZE shares at 2025-09-30, 42,970,640 shares in all. 23 filers opened a position and 3 filers sold out during the quarter.

Managers
93
13F filers
94
New
23
Added
39
Reduced
15
Sold out
3
Shares held by filers
42,970,640

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
TRV GP IV, LLC6,073,958$157M57.49%013F-HRTimeline
Frazier Life Sciences Management, L.P.4,567,274$118M3.55%-113F-HRTimeline
ARCH Venture Management, LLC4,120,053$107M21.7%013F-HRTimeline
Deep Track Capital, LP3,948,910$102M2.86%013F-HRTimeline
Alphabet Inc.in group Alphabet Inc.2,412,471$62.6M2.6%013F-HRTimelineGroup
a16z Capital Management, L.L.C.in group a16z Capital Management, L.L.…1,702,225$44.1M3.16%013F-HRTimelineGroup
Matrix Capital Management Company, LP1,653,684$42.9M40.17%-832,50013F-HRTimeline
VANGUARD GROUP INCin group VANGUARD GROUP INC1,334,955$34.6M<0.01%+915,34213F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.1,316,016$34.1M<0.01%+701,31213F-HRTimelineGroup
Venrock Adviser, LLC1,230,769$31.9M1.8%new13F-HRTimeline
Logos Global Management LP1,227,300$31.8M3.14%+615,38613F-HRTimeline
General Catalyst Group Management, LLC1,035,910$26.9M0.88%013F-HRTimeline
Woodline Partners LP1,035,229$26.8M0.13%+94,52913F-HRTimeline
TRV GP V, LLC950,800$24.7M6.97%013F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP777,701$20.2M0.02%+758,10413F-HRTimelineGroup
Casdin Capital, LLC758,857$19.7M1.64%013F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson751,874$19.5M0.01%-649,38613F-HRTimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC740,825$19.2M3.89%+478,08513F-HRTimelineGroup
FMR LLCin group FMR LLC655,614$17M<0.01%+101,08013F-HRTimelineGroup
Foresite Capital Management VI LLCgroup of 2 filers holding608,948$15.8M-1,848,162Timeline
ArrowMark Colorado Holdings LLC545,132$14.1M0.26%new13F-HRTimeline
BESSEMER GROUP INCin group BESSEMER GROUP INC481,790$12.5M0.02%013F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC473,549$12.3M<0.01%+242,31213F-HRTimelineGroup
HHLR ADVISORS, LTD.in group HHLR ADVISORS, LTD.457,535$11.9M0.29%013F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management433,725$11.2M0.02%new13F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP384,702$9.98M<0.01%+240,01713F-HRTimelineGroup
Driehaus Capital Management LLC378,015$9.8M0.07%+184,61513F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC351,875$9.12M0.23%+276,34513F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY212,762$5.52M<0.01%+180,98113F-HR/ATimelineGroup
WASHINGTON UNIVERSITY210,681$5.46M3.06%new13F-HRTimeline
Parkman Healthcare Partners LLC200,000$5.19M0.57%new13F-HRTimeline
Octagon Capital Advisors LP177,667$4.61M0.72%013F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP176,890$4.59M<0.01%+91,34413F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co167,928$4.35M<0.01%+92,75713F-HRTimelineGroup
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.154,343$4M0.95%-202,11013F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.132,062$3.42M<0.01%+113,63213F-HRTimelineGroup
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.125,000$3.24M0.01%013F-HRTimelineGroup
Schonfeld Strategic Advisors LLC114,049$2.96M0.02%new13F-HRTimeline
Nantahala Capital Management, LLCin group Nantahala Capital Management,…93,351$2.42M0.15%new13F-HRTimelineGroup
HARVARD MANAGEMENT CO INC92,396$2.4M0.11%-545,13213F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC86,100$2.23M<0.01%new13F-HRTimeline
Ensign Peak Advisors, Inc70,665$1.83M<0.01%+52,12613F-HR/ATimeline
ALLIANCEBERNSTEIN L.P.60,100$1.56M<0.01%+28,30413F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp45,240$1.17M<0.01%+23,69413F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.30,525$792K<0.01%+30,47113F-HRTimelineGroup
Nuveen, LLCin group TIAA30,304$786K<0.01%+18,92913F-HRTimelineGroup
UBS Group AGin group UBS Group AG27,793$721K<0.01%-23,60913F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC27,615$716K<0.01%+14813F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC27,516$713K<0.01%+12,87513F-HR/ATimelineGroup
XTX Topco Ltdin group XTX Topco Ltd26,867$697K0.04%new13F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC26,045$675K0.07%new13F-HRTimelineGroup
RHUMBLINE ADVISERS20,970$544K<0.01%+13,25613F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources18,198$472K<0.01%new13F-HRTimelineGroup
STRS OHIO17,900$464K<0.01%-29,00013F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…16,165$419K<0.01%+5,59813F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN14,779$383K<0.01%+9,16413F-HRTimelineGroup
WINTON GROUP Ltdin group WINTON GROUP Ltd14,487$376K0.01%new13F-HRTimelineGroup
ALPS ADVISORS INCin group ALPS ADVISORS INC13,742$356K<0.01%-9,83513F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS12,018$312K<0.01%+11,25913F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…11,801$306K<0.01%new13F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP11,150$289K<0.01%new13F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/10,474$272K<0.01%new13F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/9,574$248K<0.01%+3,79213F-HR/ATimelineGroup
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.in group Mirae Asset Global Investment…9,078$235K<0.01%+4,17713F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\8,885$230K<0.01%013F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…8,397$218K0.06%+1,45713F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO7,890$205K<0.01%+3,52413F-HR/ATimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND6,700$174K<0.01%+4,40013F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc5,219$135K<0.01%+97713F-HRTimelineGroup
Police & Firemen's Retirement System of…5,030$130K<0.01%+2,78913F-HRTimeline
SG Americas Securities, LLC5,015$130K<0.01%new13F-HRTimeline
Caption Management, LLC4,000$104K0.01%new13F-HRTimeline
CWM, LLCin group CWM, LLC2,138$55K<0.01%-12813F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…2,012$52.2K<0.01%-2,59613F-HRTimelineGroup
China Universal Asset Management Co., L…2,000$51.9K<0.01%new13F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…1,907$49.4K<0.01%+1,72513F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…1,632$42.3K<0.01%+73813F-HRTimelineGroup
Sterling Capital Management LLC1,260$32.7K<0.01%+1,03613F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…555$14.4K<0.01%+113F-HRTimeline
Farther Finance Advisors, LLC383$9.93K<0.01%new13F-HRTimeline
AMALGAMATED BANK305$8K<0.01%013F-HRTimeline
Arax Advisory Partners307$7.96K<0.01%new13F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA283$7K<0.01%-80313F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC269$6.98K<0.01%-12,72113F-HRTimelineGroup
GAMMA Investing LLC159$4.12K<0.01%+10813F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…149$3.86K<0.01%+3513F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…93$2.41K<0.01%new13F-HRTimelineGroup
SBI Securities Co., Ltd.61$1.58K<0.01%-44413F-HRTimeline
NISA INVESTMENT ADVISORS, LLC26$674<0.01%013F-HRTimeline
Sunbelt Securities, Inc.12$311<0.01%new13F-HRTimeline
ROTHSCHILD INVESTMENT LLC10$259<0.01%new13F-HRTimeline
Essential Partners LLC7$182<0.01%013F-HRTimeline
True Wealth Design, LLC5$130<0.01%013F-HRTimeline