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13F-HR filed by ARCH Venture Management, LLC

ARCH Venture Management, LLC filed this 13F-HR for the quarter ended 2025-09-30, filed 2025-11-14, with 9 holding rows worth $492,363,653.

Accession
0001012975-25-000787
Filed
2025-11-14
Accepted by EDGAR
acceptance time not in the bulk data set
Ingested
Source
SEC quarterly data set

Original filing

13F report for Q3 2025

A holdings report, 9 entries on the cover page, a total value of $492,363,653 stated on the cover page (in dollars after the unit check, H1), rows summing to $492,363,653 with VALUE read as dollars as filed, 13F file number 028-19358. The quarter's positions are built on this report. The resolved quarter.

The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).

Issuer as filedCUSIPClassAmountValueValue read asType
RAPPORT THERAPEUTICS INC COM75383L102Stock3,728,738$110,743,519dollars as filed
BEAM THERAPEUTICS INC07373V105COM4,540,132$110,189,004dollars as filed
MAZE THERAPEUTICS INC COM578784100Stock4,120,053$106,832,974dollars as filed
VIR BIOTECHNOLOGY INC92764N102COM12,916,663$73,754,146dollars as filed
LYELL IMMUNOPHARMA INC COM NEW55083R203Stock2,759,072$44,807,329dollars as filed
ERASCA INC COM29479A108Stock11,055,554$24,101,108dollars as filed
GOSSAMER BIO INC COM38341P102Stock8,055,916$21,187,059dollars as filed
Q32 BIO INC746964105Common Stock320,482$634,554dollars as filed
CERO THERAPEUTICS HLDGS INC71902K402COM22,389$113,960dollars as filed

Amendment chain

FilingRoleFiledAcceptedIngested
13F-HR 0001012975-25-000787this filing2025-11-14acceptance time not in the bulk data set