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Disclosery

DSGN DESIGN THERAPEUTICS INC

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COM (common), issuer CIK 1807120

94 managers (96 13F filers) reported a position in DSGN shares at 2024-12-31, 33,460,912 shares in all. 13 filers opened a position and 18 filers sold out during the quarter.

Managers
94
13F filers
96
New
13
Added
34
Reduced
22
Sold out
18
Shares held by filers
33,460,912

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2024

Filers in the available 13F reports with a share position at 2024-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
SR One Capital Management, LP6,526,476$40.3M9.82%013F-HRTimeline
Logos Global Management LP4,217,627$26M3.04%013F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.2,579,599$15.9M<0.01%+220,80213F-HRTimelineGroup
Frazier Life Sciences Management, L.P.1,953,547$12.1M0.5%+61,00013F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.1,856,750$11.5M0.03%+256,01013F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP1,743,725$10.8M0.11%013F-HRTimelineGroup
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC1,480,975$9.14M0.6%013F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC1,430,745$8.83M<0.01%+36,72113F-HRTimelineGroup
Almitas Capital LLC1,323,667$8.17M1.79%013F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC958,793$5.92M0.01%+383,24313F-HRTimelineGroup
FMR LLCin group FMR LLC951,882$5.87M<0.01%+123,21713F-HRTimelineGroup
Driehaus Capital Management LLC776,082$4.79M0.04%new13F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC761,640$4.7M<0.01%+3,09013F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP723,319$4.46M<0.01%+32,49313F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC567,604$3.5M0.01%-15,55613F-HRTimelineGroup
MPM BIOIMPACT LLC559,547$3.45M0.49%new13F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.512,330$3.16M<0.01%-70,52813F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding437,831$2.7M-171,313Timeline
EcoR1 Capital, LLC426,683$2.63M0.11%+372,84913F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP388,125$2.39M<0.01%+51,35113F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY346,183$2.14M<0.01%-82,61513F-HR/ATimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC297,129$1.83M<0.01%+21,59713F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co264,675$1.63M<0.01%+7,24313F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC253,500$1.56M<0.01%-20,50013F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP215,265$1.33M<0.01%+80,90513F-HRTimelineGroup
Nuveen Asset Management, LLCin group TIAA158,004$975K<0.01%-54,55013F-HRTimelineGroup
Walleye Capital LLCin group Walleye Capital LLC141,127$871K0.01%+71,12713F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC128,400$792K0.02%-107,20013F-HRTimeline
GSA CAPITAL PARTNERS LLP118,328$730K0.05%-55,41613F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC103,571$639K<0.01%+6,93613F-HR/ATimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp95,348$588K<0.01%-3,77713F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO89,215$550K<0.01%+48,52813F-HRTimelineGroup
UBS Group AGin group UBS Group AG66,587$411K<0.01%+51,70713F-HRTimelineGroup
Assenagon Asset Management S.A.56,617$349K<0.01%-289,57513F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC56,315$347K<0.01%-2,80013F-HRTimelineGroup
Palumbo Wealth Management LLC54,696$337K0.13%+17,92213F-HRTimeline
RHUMBLINE ADVISERS52,932$327K<0.01%+2,36513F-HR/ATimeline
XTX Topco Ltdin group XTX Topco Ltd48,424$299K0.03%new13F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC48,186$297K<0.01%-36,94513F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.42,090$260K<0.01%013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS40,289$249K<0.01%new13F-HRTimelineGroup
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC39,115$241K<0.01%+6,48113F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…37,312$230K<0.01%new13F-HRTimelineGroup
PDT Partners, LLC36,099$223K0.02%013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/35,160$217K<0.01%-1,65113F-HRTimelineGroup
STRS OHIO32,600$201K<0.01%013F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC29,855$184K<0.01%+19,07113F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\28,094$173K<0.01%013F-HR/ATimelineGroup
Corient Private Wealth LPin group Corient Private Wealth LP26,965$166K<0.01%013F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC24,476$151K<0.01%+1,33113F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding19,844$123K+2,647Timeline
MetLife Investment Management, LLCin group MetLife Investment Management…19,334$119K<0.01%013F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN18,428$114K<0.01%+4,01313F-HRTimelineGroup
JACOBS LEVY EQUITY MANAGEMENT, INC18,261$113K<0.01%-262,01013F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC17,665$109K<0.01%new13F-HRTimeline
Mariner, LLCin group Mariner, LLC16,257$100K<0.01%+12913F-HRTimelineGroup
ALGERT GLOBAL LLC16,238$100K<0.01%+1,86013F-HR/ATimeline
Corebridge Financial, Inc.in group Corebridge Financial, Inc.15,610$96.3K<0.01%-1,17913F-HRTimelineGroup
CAZ INVESTMENTS LPin group CAZ INVESTMENTS LP15,000$93K0.13%013F-HRTimelineGroup
KENNEDY CAPITAL MANAGEMENT LLC14,266$88K<0.01%new13F-HRTimeline
SG Americas Securities, LLC13,667$84K<0.01%+1,37813F-HRTimeline
Bleakley Financial Group, LLC13,266$81.9K<0.01%+1,67513F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …13,070$80.6K<0.01%-15113F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/12,451$77K<0.01%+2,16713F-HRTimeline
China Universal Asset Management Co., L…12,006$74.1K0.01%new13F-HRTimeline
NISA INVESTMENT ADVISORS, LLC11,855$73.1K<0.01%-5013F-HRTimeline
Invesco Ltd.in group Invesco Ltd.11,583$71.5K<0.01%new13F-HRTimelineGroup
ProShare Advisors LLC11,525$71.1K<0.01%new13F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…9,219$56.9K<0.01%013F-HRTimelineGroup
Police & Firemen's Retirement System of…6,598$40.7K<0.01%13F-HRTimeline
SIMPLEX TRADING, LLC5,168$31K<0.01%-2,43413F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA4,067$25K<0.01%-85613F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…3,059$18.9K<0.01%-1,43313F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…2,570$15.9K<0.01%013F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc2,565$15.8K<0.01%013F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…2,275$14K<0.01%013F-HR/ATimeline
NEW YORK STATE COMMON RETIREMENT FUND2,026$12.5K<0.01%013F-HR/ATimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,761$10.9K<0.01%+5613F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.1,189$7.34K<0.01%13F-HRTimeline
AMALGAMATED BANK1,176$7K<0.01%013F-HRTimeline
GAMMA Investing LLC1,070$6.6K<0.01%+65313F-HRTimeline
Sterling Capital Management LLC1,005$6.2K<0.01%+90313F-HRTimeline
Venturi Wealth Management, LLC753$4.65K<0.01%new13F-HRTimeline
CoreCap Advisors, LLC712$4.39K<0.01%new13F-HRTimeline
Clearstead Advisors, LLC610$3.76K<0.01%013F-HRTimeline
Private Wealth Management Group, LLC558$3.44K<0.01%013F-HRTimeline
MassMutual Private Wealth & Trust, FSB239$1.48K<0.01%013F-HRTimeline
CWM, LLCin group CWM, LLC141$1K<0.01%+1713F-HRTimelineGroup
Arax Advisory Partners143$883<0.01%-10113F-HRTimeline
PRINCIPAL SECURITIES, INC.in group PRINCIPAL FINANCIAL GROUP INC74$457<0.01%013F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.73$450<0.01%+6313F-HR/ATimelineGroup
Farther Finance Advisors, LLC19$117<0.01%013F-HRTimeline
Capital Advisors, Ltd. LLC12$00%013F-HRTimelineValue filed as zero, left out of ratios.
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$00%013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.