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Disclosery

DSGN DESIGN THERAPEUTICS INC

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COM (common), issuer CIK 1807120

120 managers (125 13F filers) reported a position in DSGN shares at 2026-03-31, 37,986,626 shares in all. 18 filers opened a position and 13 filers sold out during the quarter.

Managers
120
13F filers
125
New
18
Added
56
Reduced
28
Sold out
13
Shares held by filers
37,986,626

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2026

Filers in the available 13F reports with a share position at 2026-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
SR One Capital Management, LP6,526,476$69.4M7.59%013F-HRTimeline
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.2,972,973$31.6M0.34%+1,511,59213F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.2,722,754$29M0.05%-2,649,25013F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP2,585,978$27.5M0.16%+352,87913F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.2,133,764$22.7M<0.01%+16,60813F-HRTimelineGroup
Logos Global Management LP1,950,000$20.7M1.07%-550,00013F-HRTimeline
Driehaus Capital Management LLC1,744,987$18.6M0.14%+565,17013F-HRTimeline
VANGUARD GROUP INCgroup of 4 filers holding1,695,912$18MnewTimeline
Vivo Capital, LLC1,612,903$17.2M1.43%013F-HR/ATimeline
Almitas Capital LLC1,530,335$16.3M3.68%-10013F-HRTimeline
Woodline Partners LP961,501$10.2M0.04%+17,46213F-HR/ATimeline
Trails Edge Capital Partners, LP852,013$9.07M2.13%new13F-HRTimeline
FMR LLCin group FMR LLC798,411$8.5M<0.01%+27,14313F-HRTimelineGroup
Kynam Capital Management, LP784,606$8.35M0.53%013F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC692,518$7.37M<0.01%+12,92813F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP659,575$7.02M<0.01%+11,93913F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY656,565$6.99M<0.01%-45,74113F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC616,481$6.55M0.01%+3,71313F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC504,718$5.37M<0.01%+234,06413F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.470,270$5M<0.01%+31,37613F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP431,840$4.59M<0.01%+133,91913F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC408,200$4.34M0.01%+121,10013F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP300,279$3.19M<0.01%+13,70713F-HRTimelineGroup
JACOBS LEVY EQUITY MANAGEMENT, INC289,385$3.08M0.01%+94,77413F-HRTimeline
KENNEDY CAPITAL MANAGEMENT LLC271,554$2.89M0.06%+221,53113F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co241,485$2.57M<0.01%+4,62213F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC231,513$2.46M<0.01%-228,36113F-HRTimelineGroup
Elmind Capital, LP207,900$2.21M0.63%013F-HRTimeline
ALGERT GLOBAL LLC204,739$2.18M0.03%+16,97013F-HR/ATimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP151,008$1.61M<0.01%-74,52013F-HRTimelineGroup
ACUTA CAPITAL PARTNERS, LLC145,900$1.55M1.1%-5,00613F-HRTimeline
Invesco Ltd.in group Invesco Ltd.141,920$1.51M<0.01%-163,83713F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO133,203$1.42M<0.01%+80,47313F-HRTimelineGroup
Nuveen, LLCin group TIAA126,815$1.35M<0.01%+1,55513F-HRTimelineGroup
Lynx1 Capital Management LPin group Lynx1 Capital Management LP119,516$1.27M0.2%+50,00013F-HRTimelineGroup
Trexquant Investment LP117,111$1.25M0.01%+17,14413F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC108,928$1.16M<0.01%-71,93813F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC108,449$1.15M<0.01%-1,31413F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC103,902$1.11M<0.01%-122,61013F-HRTimelineGroup
Verdad Advisers, LP92,310$982K1.11%new13F-HRTimeline
Caption Management, LLC86,708$923K0.04%new13F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC86,117$916K<0.01%+39,97513F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp79,645$847K<0.01%-5,33013F-HRTimelineGroup
Informed Momentum Co LLC78,949$840K0.1%013F-HRTimeline
Palumbo Wealth Management LLC71,408$760K0.19%+2,03113F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC65,638$698K<0.01%+7,84013F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd60,939$648K0.01%+25,65513F-HRTimelineGroup
CANADA PENSION PLAN INVESTMENT BOARD60,400$643K<0.01%+5,80013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC55,790$594K<0.01%-31,27013F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC52,000$553K0.01%-26,50013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS50,272$535K<0.01%-44,55613F-HRTimelineGroup
ALPS ADVISORS INCin group ALPS ADVISORS INC50,209$534K<0.01%+3,43813F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD49,214$524K<0.01%-1,44313F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC45,810$487K<0.01%+3,10013F-HRTimelineGroup
STRS OHIO44,700$476K<0.01%+19,50013F-HRTimeline
ALLIANCEBERNSTEIN L.P.46,120$433K<0.01%013F-HRTimeline
China Universal Asset Management Co., L…35,109$374K0.03%+82713F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC34,990$372K<0.01%-123,39313F-HR/ATimelineGroup
RHUMBLINE ADVISERS34,860$371K<0.01%+8213F-HRTimeline
Qube Research & Technologies Ltd34,183$364K<0.01%new13F-HRTimeline
Corient Private Wealth LPin group Corient Private Wealth LP27,169$289K<0.01%+20413F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC25,957$276K<0.01%+12,22713F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…25,437$271K<0.01%+20313F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/23,264$248K<0.01%-4,18213F-HRTimelineGroup
AlphaCentric Advisors LLC21,231$226K0.23%+96913F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\20,644$220K<0.01%+5,10313F-HRTimelineGroup
Velan Capital Investment Management LP20,000$213K0.13%013F-HRTimeline
UBS Group AGgroup of 2 filers holding18,234$194K-7,683Timeline
PRICE T ROWE ASSOCIATES INC /MD/16,370$175K<0.01%+65913F-HRTimeline
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP16,300$173K<0.01%-29,93713F-HRTimelineGroup
Engineers Gate Manager LP16,090$171K<0.01%+2,07813F-HRTimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…15,294$163K<0.01%new13F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…15,249$162K<0.01%013F-HRTimelineGroup
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF O…15,193$162K<0.01%+8,10013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC14,824$158K<0.01%+3,00013F-HRTimeline
Dynamic Technology Lab Private Ltd14,749$157K0.03%new13F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding14,334$153K+475Timeline
Quantinno Capital Management LP14,128$150K<0.01%new13F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO14,134$147K<0.01%-31713F-HR/ATimelineGroup
Mariner, LLCin group Mariner, LLC13,066$139K<0.01%+24413F-HRTimelineGroup
Baader Bank Aktiengesellschaft12,792$136K0.01%-7,20813F-HRTimeline
MIRABELLA FINANCIAL SERVICES LLP11,814$126K0.01%new13F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA11,366$121K<0.01%+10,72813F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC10,000$106K0.01%new13F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN9,027$96K<0.01%-17,75913F-HR/ATimelineGroup
Police & Firemen's Retirement System of…6,598$70.2K<0.01%013F-HRTimeline
CITIGROUP INCin group CITIGROUP INC4,263$45.4K<0.01%+1,15013F-HRTimelineGroup
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…3,684$39.2K<0.01%+2,94613F-HRTimelineGroup
CAZ INVESTMENTS LPin group CAZ INVESTMENTS LP3,500$37.2K0.04%013F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…2,570$27.3K<0.01%013F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc2,077$22.1K<0.01%013F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND2,026$21.6K<0.01%013F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…1,816$19.3K<0.01%013F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…1,594$17K<0.01%+36713F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…1,545$16.4K<0.01%-2,72813F-HRTimelineGroup
GAMMA Investing LLC1,472$15.7K<0.01%+72213F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…1,292$13.7K<0.01%-17913F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,271$13.5K<0.01%+15313F-HRTimeline
Sterling Capital Management LLC791$8.42K<0.01%-58613F-HRTimeline
Clearstead Advisors, LLC610$6.49K<0.01%013F-HRTimeline
Private Wealth Management Group, LLC533$5.67K<0.01%-2513F-HRTimeline
CWM, LLCin group CWM, LLC423$4.5K<0.01%+18413F-HRTimelineGroup
Farther Finance Advisors, LLC386$4.25K<0.01%+113F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.306$3.26K<0.01%+29613F-HRTimelineGroup
Physician Wealth Advisors, Inc.268$2.85K<0.01%013F-HRTimeline
MassMutual Private Wealth & Trust, FSB239$2.54K<0.01%013F-HRTimeline
Stone House Investment Management, LLC239$2.54K<0.01%new13F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.224$2.38K<0.01%-10413F-HR/ATimelineGroup
Larson Financial Group LLC181$1.93K<0.01%+17813F-HRTimeline
Allworth Financial LP130$1.38K<0.01%new13F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\61$649<0.01%new13F-HRTimelineGroup
Root Financial Partners, LLC38$404<0.01%new13F-HRTimeline
ROTHSCHILD INVESTMENT LLC23$245<0.01%new13F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…10$107<0.01%+713F-HR/ATimelineGroup
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/9$96<0.01%new13F-HRTimelineGroup
MAI Capital Management8$86<0.01%new13F-HRTimeline
Caitong International Asset Management …1$11<0.01%new13F-HRTimeline
True Wealth Design, LLC1$11<0.01%013F-HRTimeline
Essential Partners LLC1$11<0.01%new13F-HRTimeline
Capital Advisors, Ltd. LLC12$00%013F-HRTimelineValue filed as zero, left out of ratios.