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Disclosery

DSGN DESIGN THERAPEUTICS INC

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COM (common), issuer CIK 1807120

97 managers (99 13F filers) reported a position in DSGN shares at 2025-03-31, 34,459,627 shares in all. 13 filers opened a position and 10 filers sold out during the quarter.

Managers
97
13F filers
99
New
13
Added
28
Reduced
36
Sold out
10
Shares held by filers
34,459,627

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2025

Filers in the available 13F reports with a share position at 2025-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
SR One Capital Management, LP6,526,476$25.2M6.47%013F-HRTimeline
Logos Global Management LP4,217,627$16.3M2.89%013F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.2,479,963$9.57M<0.01%-99,63613F-HRTimelineGroup
Frazier Life Sciences Management, L.P.1,953,547$7.54M0.34%013F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.1,817,858$7.02M0.02%-38,89213F-HR/ATimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP1,743,725$6.73M0.07%013F-HRTimelineGroup
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC1,680,975$6.49M0.36%+200,00013F-HRTimelineGroup
Almitas Capital LLC1,452,896$5.61M1.86%+129,22913F-HRTimeline
VANGUARD GROUP INCin group VANGUARD GROUP INC1,427,467$5.51M<0.01%-3,27813F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC963,460$3.72M<0.01%+4,66713F-HRTimelineGroup
FMR LLCin group FMR LLC948,050$3.66M<0.01%-3,83213F-HRTimelineGroup
Driehaus Capital Management LLC913,399$3.53M0.03%+137,31713F-HRTimeline
Kynam Capital Management, LP904,017$3.49M0.3%new13F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC775,497$2.99M<0.01%+13,85713F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP714,074$2.76M<0.01%-9,24513F-HRTimelineGroup
Woodline Partners LP645,694$2.49M0.02%new13F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC630,953$2.43M0.01%+63,34913F-HRTimelineGroup
MPM BIOIMPACT LLC562,943$2.17M0.37%+3,39613F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.395,251$1.53M<0.01%-117,07913F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP373,653$1.44M<0.01%-14,47213F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP288,602$1.11M<0.01%+73,33713F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding275,447$1.06M-162,384Timeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC266,016$1.03M<0.01%-31,11313F-HR/ATimelineGroup
RENAISSANCE TECHNOLOGIES LLC265,000$1.02M<0.01%+11,50013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co258,375$997K<0.01%-6,30013F-HR/ATimelineGroup
MORGAN STANLEYin group MORGAN STANLEY247,878$957K<0.01%-98,30513F-HRTimelineGroup
Nuveen, LLCin group TIAA147,228$568K<0.01%13F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…141,519$546K<0.01%new13F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC113,800$439K0.01%-14,60013F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp95,348$368K<0.01%013F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC87,988$340K<0.01%new13F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC84,006$324K<0.01%-19,56513F-HR/ATimelineGroup
GSA CAPITAL PARTNERS LLP72,149$278K0.03%-46,17913F-HRTimeline
Lynx1 Capital Management LPin group Lynx1 Capital Management LP65,954$255K0.09%new13F-HRTimelineGroup
Palumbo Wealth Management LLC58,278$225K0.08%+3,58213F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC56,405$218K<0.01%+9013F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS52,872$204K<0.01%+12,58313F-HRTimelineGroup
RHUMBLINE ADVISERS46,369$179K<0.01%-6,56313F-HR/ATimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC44,415$171K<0.01%+5,30013F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…43,223$167K<0.01%+5,91113F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.42,090$162K<0.01%013F-HRTimeline
Assenagon Asset Management S.A.36,917$142K<0.01%-19,70013F-HRTimeline
UBS Group AGin group UBS Group AG32,819$127K<0.01%-33,76813F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC31,740$123K<0.01%+1,88513F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\28,129$109K<0.01%+3513F-HRTimelineGroup
Corient Private Wealth LPin group Corient Private Wealth LP26,965$104K<0.01%013F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC22,879$88.3K<0.01%-1,59713F-HRTimelineGroup
STRS OHIO22,600$87.2K<0.01%-10,00013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/22,166$85.6K<0.01%-12,99413F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD21,962$84.8K<0.01%new13F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding20,632$80.3K+788Timeline
INTECH INVESTMENT MANAGEMENT LLC20,550$79.3K<0.01%+2,88513F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO19,277$74.4K<0.01%-69,93813F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…18,962$73.2K<0.01%-37213F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN18,846$72.7K<0.01%+41813F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC18,125$70K<0.01%new13F-HR/ATimelineGroup
JACOBS LEVY EQUITY MANAGEMENT, INC17,482$67.5K<0.01%-77913F-HRTimeline
Mariner, LLCin group Mariner, LLC15,471$59.7K<0.01%-78613F-HRTimelineGroup
Corebridge Financial, Inc.in group Corebridge Financial, Inc.15,383$59.4K<0.01%-22713F-HRTimelineGroup
CAZ INVESTMENTS LPin group CAZ INVESTMENTS LP15,000$58K0.42%013F-HRTimelineGroup
KENNEDY CAPITAL MANAGEMENT LLC14,383$55.5K<0.01%+11713F-HRTimeline
Velan Capital Investment Management LP14,000$54K0.06%new13F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/13,069$51K<0.01%+61813F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …12,957$50K<0.01%-11313F-HRTimelineGroup
SG Americas Securities, LLC12,980$50K<0.01%-68713F-HRTimeline
NISA INVESTMENT ADVISORS, LLC11,916$46K<0.01%+6113F-HRTimeline
China Universal Asset Management Co., L…11,357$43.8K<0.01%-64913F-HRTimeline
Invesco Ltd.in group Invesco Ltd.11,331$43.7K<0.01%-25213F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…9,251$35.7K<0.01%+3213F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…7,902$30.5K<0.01%+6,14113F-HRTimelineGroup
Police & Firemen's Retirement System of…6,598$25.5K<0.01%013F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…3,940$15.2K<0.01%+88113F-HRTimelineGroup
CoreCap Advisors, LLC2,879$11.1K<0.01%+2,16713F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA2,806$11K<0.01%-1,26113F-HR/ATimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…2,570$9.92K<0.01%013F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc2,565$9.91K<0.01%013F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…2,275$8.78K<0.01%013F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…2,165$8.36K<0.01%new13F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND2,026$7.82K<0.01%013F-HR/ATimeline
GF FUND MANAGEMENT CO. LTD.1,449$5.59K<0.01%+26013F-HRTimeline
AMALGAMATED BANK1,176$5K<0.01%013F-HRTimeline
Clearstead Advisors, LLC610$2.35K<0.01%013F-HRTimeline
Private Wealth Management Group, LLC558$2.15K<0.01%013F-HRTimeline
Sterling Capital Management LLC542$2.09K<0.01%-46313F-HRTimeline
COLDSTREAM CAPITAL MANAGEMENT INC535$2.07K<0.01%new13F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.350$1K<0.01%new13F-HRTimelineGroup
SIMPLEX TRADING, LLC263$1K<0.01%-4,90513F-HRTimeline
MassMutual Private Wealth & Trust, FSB239$923<0.01%013F-HRTimeline
GAMMA Investing LLC228$880<0.01%-84213F-HR/ATimeline
PRINCIPAL SECURITIES, INC.in group PRINCIPAL FINANCIAL GROUP INC74$457<0.01%013F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.49$189<0.01%-2413F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…31$120<0.01%new13F-HRTimelineGroup
Brooklyn Investment Group19$74<0.01%new13F-HRTimeline
Farther Finance Advisors, LLC19$68<0.01%013F-HRTimeline
CWM, LLCin group CWM, LLC111$00%-3013F-HRTimelineGroupValue filed as zero, left out of ratios.
Capital Advisors, Ltd. LLC12$00%013F-HRTimelineValue filed as zero, left out of ratios.
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.