JANUS HENDERSON GROUP PLC in group Janus Henderson More: the full row for JANUS HENDERSON GROUP PLC 1,284,324 $93.5M 0.04% +128,329 13F-HR/A Timeline Group Cormorant Asset Management, LP More: the full row for Cormorant Asset Management, LP 1,059,331 $77.3M 3.9% 0 13F-HR Timeline BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 621,933 $45.4M <0.01% +227,890 13F-HR Timeline Group Vivo Capital, LLC More: the full row for Vivo Capital, LLC 557,172 $40.7M 3.38% +55,555 13F-HR/A Timeline BRAIDWELL LP More: the full row for BRAIDWELL LP 539,708 $39.4M 1.31% +215,350 13F-HR Timeline ADAGE CAPITAL PARTNERS GP, L.L.C. in group ADAGE CAPITAL PARTNERS GP, L.… More: the full row for ADAGE CAPITAL PARTNERS GP, L.L.C. 495,743 $36.2M 0.06% +100,000 13F-HR Timeline Group Vestal Point Capital, LP More: the full row for Vestal Point Capital, LP 492,319 $35.9M 1% new 13F-HR Timeline Driehaus Capital Management LLC More: the full row for Driehaus Capital Management LLC 432,515 $31.6M 0.23% +162,874 13F-HR Timeline PERCEPTIVE ADVISORS LLC in group PERCEPTIVE ADVISORS LLC More: the full row for PERCEPTIVE ADVISORS LLC 377,544 $27.5M 0.54% -71,746 13F-HR/A Timeline Group Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 297,158 $21.7M 0.04% +71,746 13F-HR Timeline Group DEERFIELD MANAGEMENT COMPANY, L.P. in group DEERFIELD MANAGEMENT COMPANY,… More: the full row for DEERFIELD MANAGEMENT COMPANY, L.P. 283,000 $20.7M 0.24% new 13F-HR Timeline Group RA CAPITAL MANAGEMENT, L.P. in group RA CAPITAL MANAGEMENT, L.P. More: the full row for RA CAPITAL MANAGEMENT, L.P. 265,000 $19.3M 0.2% new 13F-HR Timeline Group GREAT POINT PARTNERS LLC More: the full row for GREAT POINT PARTNERS LLC 220,000 $16.1M 3.93% new 13F-HR Timeline MPM BIOIMPACT LLC More: the full row for MPM BIOIMPACT LLC 212,175 $15.5M 1.2% -17,972 13F-HR Timeline Ikarian Capital, LLC in group Ikarian Capital, LLC More: the full row for Ikarian Capital, LLC 166,647 $12.2M 1.74% +7,226 13F-HR Timeline Group WELLINGTON MANAGEMENT GROUP LLP in group WELLINGTON MANAGEMENT GROUP L… More: the full row for WELLINGTON MANAGEMENT GROUP LLP 136,677 $9.97M <0.01% +122,989 13F-HR Timeline Group MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 132,764 $9.69M <0.01% +642 13F-HR Timeline Group EVENTIDE ASSET MANAGEMENT, LLC More: the full row for EVENTIDE ASSET MANAGEMENT, LLC 130,013 $9.49M 0.16% +27,000 13F-HR Timeline SEVEN GRAND MANAGERS, LLC More: the full row for SEVEN GRAND MANAGERS, LLC 120,000 $8.76M 0.59% +70,000 13F-HR Timeline ACUTA CAPITAL PARTNERS, LLC More: the full row for ACUTA CAPITAL PARTNERS, LLC 111,996 $8.17M 5.81% +27,519 13F-HR Timeline STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 108,239 $7.9M <0.01% +30,961 13F-HR Timeline Group GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 88,716 $6.47M <0.01% +25,170 13F-HR Timeline Group Sio Capital Management, LLC More: the full row for Sio Capital Management, LLC 86,083 $6.28M 0.91% +4,200 13F-HR Timeline GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 74,369 $5.43M <0.01% +25,822 13F-HR Timeline Group VANGUARD GROUP INC group of 3 filers holding More: the full row for VANGUARD GROUP INC 69,602 $5.08M new Timeline B Group, Inc. More: the full row for B Group, Inc. 67,500 $4.93M 3.65% new 13F-HR Timeline Walleye Capital LLC in group Walleye Capital LLC More: the full row for Walleye Capital LLC 53,706 $3.92M 0.02% +27,880 13F-HR/A Timeline Group MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 52,832 $3.86M <0.01% -141,605 13F-HR Timeline Group BOOTHBAY FUND MANAGEMENT, LLC More: the full row for BOOTHBAY FUND MANAGEMENT, LLC 51,290 $3.74M 0.09% +3,800 13F-HR Timeline AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 50,027 $3.65M <0.01% new 13F-HR/A Timeline Group Woodline Partners LP More: the full row for Woodline Partners LP 45,668 $3.33M 0.01% new 13F-HR/A Timeline Parkman Healthcare Partners LLC More: the full row for Parkman Healthcare Partners LLC 40,098 $2.93M 0.3% new 13F-HR Timeline ORBIMED ADVISORS LLC in group ORBIMED ADVISORS LLC More: the full row for ORBIMED ADVISORS LLC 40,000 $2.92M 0.06% new 13F-HR Timeline Group Artia Global Partners LP More: the full row for Artia Global Partners LP 38,407 $2.8M 0.63% +5,000 13F-HR Timeline NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 37,378 $2.73M <0.01% +11,808 13F-HR Timeline Group ADAR1 Capital Management, LLC in group ADAR1 Capital Management, LLC More: the full row for ADAR1 Capital Management, LLC 33,900 $2.47M 0.15% +30,400 13F-HR Timeline Group KVP Capital Advisors, LP More: the full row for KVP Capital Advisors, LP 31,813 $2.32M 1.73% new 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 19,422 $1.42M <0.01% +4,347 13F-HR Timeline Group PLATINUM INVESTMENT MANAGEMENT LTD More: the full row for PLATINUM INVESTMENT MANAGEMENT LTD 19,127 $1.4M 0.35% -2,603 13F-HR Timeline D. E. Shaw & Co., Inc. in group D. E. Shaw & Co., Inc. More: the full row for D. E. Shaw & Co., Inc. 15,445 $1.13M <0.01% +11,528 13F-HR Timeline Group CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 15,318 $1.12M <0.01% +2,853 13F-HR Timeline Group SUPERSTRING CAPITAL MANAGEMENT LP More: the full row for SUPERSTRING CAPITAL MANAGEMENT LP 13,311 $971K 0.69% -33,967 13F-HR Timeline UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 13,280 $969K <0.01% -533 13F-HR Timeline Group Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 13,253 $967K <0.01% +3,264 13F-HR Timeline Group Schonfeld Strategic Advisors LLC More: the full row for Schonfeld Strategic Advisors LLC 13,244 $966K 0.01% -16,967 13F-HR Timeline AdvisorShares Investments LLC More: the full row for AdvisorShares Investments LLC 12,613 $920K 0.17% +2,669 13F-HR Timeline SEI INVESTMENTS CO in group SEI INVESTMENTS CO More: the full row for SEI INVESTMENTS CO 11,188 $816K <0.01% new 13F-HR Timeline Group Ghisallo Capital Management LLC More: the full row for Ghisallo Capital Management LLC 11,000 $803K 0.02% new 13F-HR Timeline Informed Momentum Co LLC More: the full row for Informed Momentum Co LLC 9,189 $671K 0.08% new 13F-HR Timeline Nuveen, LLC in group TIAA More: the full row for Nuveen, LLC 8,329 $608K <0.01% +2,342 13F-HR Timeline Group RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 7,762 $566K <0.01% +1,826 13F-HR Timeline Trexquant Investment LP More: the full row for Trexquant Investment LP 7,451 $544K <0.01% new 13F-HR Timeline Quadrature Capital Ltd in group Quadrature Capital Ltd More: the full row for Quadrature Capital Ltd 6,498 $474K 0.01% new 13F-HR Timeline Group LPL Financial LLC More: the full row for LPL Financial LLC 6,495 $474K <0.01% +850 13F-HR Timeline JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 6,400 $467K <0.01% -2,618 13F-HR Timeline Group Seven Fleet Capital Management LP More: the full row for Seven Fleet Capital Management LP 6,395 $467K 0.15% new 13F-HR/A Timeline Invesco Ltd. in group Invesco Ltd. More: the full row for Invesco Ltd. 6,296 $459K <0.01% +2,098 13F-HR Timeline Group DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 6,258 $457K <0.01% +1,999 13F-HR Timeline Group PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 4,947 $361K <0.01% +2,117 13F-HR Timeline DNB Asset Management AS in group DNB Asset Management AS More: the full row for DNB Asset Management AS 4,441 $324K <0.01% new 13F-HR Timeline Group MetLife Investment Management, LLC in group MetLife Investment Management… More: the full row for MetLife Investment Management, LLC 3,911 $285K <0.01% +993 13F-HR Timeline Group STATE BOARD OF ADMINISTRATION OF FLORID… More: the full row for STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 3,781 $276K <0.01% 0 13F-HR Timeline JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 3,877 $265K <0.01% +1,361 13F-HR/A Timeline Group MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. in group Mirae Asset Global Investment… More: the full row for MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 3,260 $238K <0.01% +937 13F-HR Timeline Group SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 3,141 $229K <0.01% new 13F-HR Timeline Group Virtu Financial LLC in group Virtu Financial LLC More: the full row for Virtu Financial LLC 3,129 $228K 0.01% +232 13F-HR Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 3,077 $225K <0.01% -6,583 13F-HR Timeline Group STRS OHIO More: the full row for STRS OHIO 2,700 $197K <0.01% +1,800 13F-HR Timeline NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 2,600 $190K <0.01% 0 13F-HR Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 2,532 $185K <0.01% -2,991 13F-HR/A Timeline Group Persistent Asset Partners Ltd More: the full row for Persistent Asset Partners Ltd 2,310 $169K 0.07% new 13F-HR Timeline Aquatic Capital Management LLC More: the full row for Aquatic Capital Management LLC 2,045 $149K <0.01% new 13F-HR Timeline Police & Firemen's Retirement System of… More: the full row for Police & Firemen's Retirement System of New Jersey 2,036 $149K <0.01% +531 13F-HR Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 1,571 $115K <0.01% -24,105 13F-HR Timeline Group Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 882 $64.4K <0.01% -52 13F-HR Timeline Group FMR LLC in group FMR LLC More: the full row for FMR LLC 819 $59.8K <0.01% -292 13F-HR Timeline Group Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 616 $45K <0.01% +69 13F-HR Timeline Group Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 597 $43.6K <0.01% -485 13F-HR Timeline Group China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 500 $36.5K <0.01% new 13F-HR Timeline Ameritas Investment Partners, Inc. in group Ameritas Investment Partners,… More: the full row for Ameritas Investment Partners, Inc. 470 $34.3K <0.01% 0 13F-HR Timeline Group ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 406 $30K <0.01% -121 13F-HR Timeline Group CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 380 $27.7K <0.01% +70 13F-HR Timeline CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 297 $21.6K <0.01% +183 13F-HR Timeline Group NewEdge Advisors, LLC More: the full row for NewEdge Advisors, LLC 250 $18.2K <0.01% +200 13F-HR/A Timeline Sterling Capital Management LLC More: the full row for Sterling Capital Management LLC 45 $3.28K <0.01% +15 13F-HR Timeline GAMMA Investing LLC More: the full row for GAMMA Investing LLC 33 $2.41K <0.01% new 13F-HR Timeline CWM, LLC in group CWM, LLC More: the full row for CWM, LLC 11 $803 <0.01% +1 13F-HR Timeline Group Bell Investment Advisors, Inc More: the full row for Bell Investment Advisors, Inc 6 $438 <0.01% new 13F-HR Timeline SBI Securities Co., Ltd. More: the full row for SBI Securities Co., Ltd. 5 $365 <0.01% 0 13F-HR Timeline Allworth Financial LP More: the full row for Allworth Financial LP 3 $219 <0.01% new 13F-HR Timeline MAI Capital Management More: the full row for MAI Capital Management 1 $73 <0.01% new 13F-HR Timeline TWIN PEAKS WEALTH ADVISORS, LLC More: the full row for TWIN PEAKS WEALTH ADVISORS, LLC 1 $73 <0.01% new 13F-HR Timeline