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Disclosery

CTMX CYTOMX THERAPEUTICS INC.

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COMMON STOCK (common), issuer CIK 1501989

118 managers (122 13F filers) reported a position in CTMX shares at 2025-12-31, 144,098,408 shares in all. 34 filers opened a position and 20 filers sold out during the quarter.

Managers
118
13F filers
122
New
34
Added
39
Reduced
25
Sold out
20
Shares held by filers
144,098,408

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
FMR LLCin group FMR LLC24,688,109$105M0.01%+9,291,90913F-HRTimelineGroup
Venrock Adviser, LLC15,561,500$66.3M3.27%013F-HRTimeline
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC9,680,185$41.2M0.76%013F-HRTimelineGroup
Kynam Capital Management, LP8,966,077$38.2M2.49%+5,319,57413F-HRTimeline
VANGUARD GROUP INCgroup of 2 filers holding8,502,349$36.2M-472,397Timeline
Commodore Capital LPin group Commodore Capital LP7,692,300$32.8M2.18%013F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.5,189,538$22.1M0.03%+1,120,96313F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP5,140,931$21.9M<0.01%+4,495,94913F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP4,250,826$18.1M0.11%013F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC4,182,769$17.8M1.33%+137,35513F-HR/ATimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management3,872,202$16.5M0.03%-40,87913F-HRTimelineGroup
Financial Engines Advisors L.L.C.3,828,717$16.3M0.03%+2,447,36013F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.3,669,393$15.6M<0.01%+1,287,48113F-HRTimelineGroup
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC3,525,650$15M0.31%-4,935,85013F-HRTimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC3,172,616$13.5M1.75%-200,00013F-HRTimelineGroup
Vivo Capital, LLC2,884,615$12.3M0.79%013F-HRTimeline
Eversept Partners, LP2,507,090$10.7M0.6%new13F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC2,460,944$10.5M<0.01%+2,013,19113F-HR/ATimelineGroup
Woodline Partners LP2,337,005$9.96M0.04%013F-HRTimeline
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding1,896,279$8.08M+1,126,581Timeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,525,666$6.5M<0.01%-43,63213F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP1,289,656$5.49M<0.01%+838,52813F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP1,156,936$4.93M<0.01%+51,94313F-HRTimelineGroup
Qube Research & Technologies Ltd1,061,128$4.52M0.01%+938,62813F-HRTimeline
STEMPOINT CAPITAL LP1,036,311$4.41M0.76%new13F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding1,029,610$4.39M+714,113Timeline
BOOTHBAY FUND MANAGEMENT, LLC894,663$3.81M0.1%-342,39413F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/876,305$3.73M<0.01%-128,92313F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC856,056$3.64M0.01%+202,33113F-HRTimelineGroup
Exome Asset Management LLC745,305$3.17M1.57%013F-HRTimeline
Elmind Capital, LP700,000$2.98M0.88%13F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC607,218$2.59M<0.01%+205,85113F-HRTimelineGroup
Assenagon Asset Management S.A.592,696$2.52M<0.01%-137,27113F-HRTimeline
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP423,168$1.8M<0.01%+21,27713F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP415,178$1.77M<0.01%+25,49313F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY401,191$1.71M<0.01%+81,90313F-HR/ATimelineGroup
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…385,974$1.64M0.24%new13F-HRTimelineGroup
SCHULHOFF & CO INC374,850$1.6M0.67%new13F-HRTimeline
UBS Group AGin group UBS Group AG370,739$1.58M<0.01%+340,57113F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC342,304$1.46M<0.01%-1,458,13113F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC336,525$1.43M<0.01%+335,03513F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp328,248$1.4M<0.01%+75,58913F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC316,971$1.35M<0.01%+23,41113F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC289,653$1.23M<0.01%-1,097,21013F-HRTimelineGroup
Rafferty Asset Management, LLC273,584$1.17M<0.01%new13F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC229,599$989K<0.01%+71,27013F-HRTimelineGroup
PRELUDE CAPITAL MANAGEMENT, LLC206,526$880K0.06%013F-HRTimeline
Informed Momentum Co LLC203,823$868K0.1%new13F-HRTimeline
HighVista Strategies LLC193,941$826K0.21%-63,20713F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO124,124$529K<0.01%new13F-HRTimelineGroup
LPL Financial LLC113,440$483K<0.01%+26,78713F-HRTimeline
CANADA PENSION PLAN INVESTMENT BOARD104,200$444K<0.01%new13F-HRTimeline
Aspire Growth Partners LLC102,254$436K0.3%013F-HRTimeline
NLB Skladi, upravljanje premozenja, d.o…100,000$426K0.02%13F-HRTimeline
PROFUND ADVISORS LLC98,633$420K0.01%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC96,326$410K<0.01%+88,57013F-HRTimelineGroup
OMERS ADMINISTRATION Corp87,800$374K<0.01%new13F-HRTimeline
GSA CAPITAL PARTNERS LLP81,886$349K0.03%-454,08813F-HRTimeline
Velan Capital Investment Management LP80,000$341K0.2%013F-HRTimeline
HRT FINANCIAL LP71,867$306K<0.01%new13F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co68,687$293K<0.01%-19,88313F-HRTimelineGroup
Miller Financial Services LLC68,000$290K0.34%+1,00013F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…63,491$270K0.07%new13F-HRTimelineGroup
Brooklyn Investment Group61,474$258K0.01%new13F-HRTimeline
Congress Park Capital LLC58,922$251K0.07%-45,00013F-HRTimeline
Merit Financial Group, LLC53,243$227K<0.01%013F-HRTimeline
SG Americas Securities, LLC53,109$226K<0.01%new13F-HRTimeline
Timothy G. Youngquist 2020 Irrevocable …51,155$218K0.19%13F-HRTimeline
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…50,990$217K<0.01%new13F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC49,897$213K<0.01%+2,16913F-HRTimelineGroup
Seven Fleet Capital Management LP48,898$208K0.14%13F-HR/ATimeline
XTX Topco Ltdin group XTX Topco Ltd47,991$204K0.01%+18,70513F-HRTimelineGroup
Formidable Asset Management, LLC45,763$195K0.03%-72,57413F-HRTimeline
Tidal Investments LLCin group Tidal Investments LLC45,763$195K<0.01%-72,57413F-HRTimelineGroup
Baader Bank Aktiengesellschaft45,000$192K0.02%new13F-HRTimeline
Private Advisor Group, LLC44,002$187K<0.01%013F-HRTimeline
Lighthouse Investment Partners, LLCin group Lighthouse Investment Partner…32,040$136K<0.01%new13F-HRTimelineGroup
Cambria Investment Management, L.P.31,332$133K0.01%new13F-HRTimeline
Empowered Funds, LLC31,332$133K<0.01%new13F-HR/ATimeline
China Universal Asset Management Co., L…27,609$118K0.01%new13F-HRTimeline
Truvestments Capital LLC27,428$117K0.02%+10,32713F-HRTimeline
Engineers Gate Manager LP26,539$113K<0.01%new13F-HRTimeline
MANGROVE PARTNERS IM, LLC26,265$112K0.01%new13F-HRTimeline
HB Wealth Management, LLC25,000$106K<0.01%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…24,794$106K<0.01%+24,79113F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO24,363$104K<0.01%+8,21113F-HRTimelineGroup
SIMPLEX TRADING, LLC24,051$102K<0.01%new13F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding24,192$101KnewTimeline
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.23,764$101K<0.01%-29,15013F-HRTimelineGroup
Ethos Financial Group, LLC23,697$101K0.01%013F-HRTimeline
Mariner, LLCin group Mariner, LLC22,180$94.5K<0.01%+11,93013F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.21,976$93.6K<0.01%-45013F-HRTimelineGroup
State of Wyoming21,511$91.6K0.01%new13F-HRTimeline
Jain Global LLC21,212$90.4K<0.01%-12,44013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.19,410$82.7K<0.01%+2,70013F-HRTimelineGroup
Sanctuary Advisors, LLC19,140$81.5K<0.01%-15,49413F-HRTimeline
Forefront Analytics, LLC18,699$79.7K0.07%+59013F-HRTimeline
TWINBEECH CAPITAL LP17,600$75K0.01%new13F-HRTimeline
WestHill Financial Advisors, Inc.17,082$72.8K0.01%013F-HRTimeline
EVOLVE PRIVATE WEALTH, LLC14,834$63.2K<0.01%13F-HRTimeline
PACES FERRY WEALTH ADVISORS, LLC14,822$63.1K0.03%new13F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC14,722$62.7K<0.01%+60113F-HRTimeline
PURSUE WEALTH PARTNERS LLC14,492$62K0.03%013F-HRTimeline
BANK OF NOVA SCOTIAin group BANK OF NOVA SCOTIA13,661$58.2K<0.01%new13F-HRTimelineGroup
Nierenberg Investment Management Compan…12,555$53.5K0.03%013F-HRTimeline
IPG Investment Advisors LLC12,500$53.2K0.01%013F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC12,230$52.1K<0.01%new13F-HR/ATimelineGroup
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…11,404$48.6K<0.01%new13F-HRTimelineGroup
Peregrine Asset Advisers, Inc.10,000$42.6K0.01%013F-HRTimeline
Farther Finance Advisors, LLC7,875$33.5K<0.01%-9513F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN6,605$28.1K<0.01%+3,00013F-HRTimelineGroup
Caitong International Asset Management …4,690$20K<0.01%+4,00113F-HR/ATimeline
GF FUND MANAGEMENT CO. LTD.3,329$14.2K<0.01%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS2,825$12K<0.01%+2,80813F-HRTimelineGroup
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.564$2K<0.01%new13F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA214$1K<0.01%-152,09013F-HRTimelineGroup
SBI Securities Co., Ltd.28$119<0.01%-5713F-HRTimeline
Inspire Investing, LLCin group Inspire Investing, LLC8$32<0.01%-522,47413F-HRTimelineGroup