13F-HR filed by Commodore Capital LP
Commodore Capital LP filed this 13F-HR for the quarter ended 2025-12-31, filed 2026-02-17, with 33 holding rows worth $1,502,245,473.
- Accession
- 0001831942-26-000004
- Filer
- CIK 1831942
- Filed
- 2026-02-17
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2025
A holdings report, 33 entries on the cover page, a total value of $1,502,245,473 stated on the cover page (in dollars after the unit check, H1), rows summing to $1,502,245,473 with VALUE read as dollars as filed, 13F file number 028-20976. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| RELAY THERAPEUTICS INC COM | 75943R102 | Stock | 17,000,000 | $143,820,000 | dollars as filed | |
| ALKERMES PLC | G01767105 | SHS | 3,550,000 | $99,329,000 | dollars as filed | |
| TYRA BIOSCIENCES INC | 90240B106 | COMMON STOCK | 3,375,000 | $88,728,750 | dollars as filed | |
| XENON PHARMACEUTICALS INC COM | 98420N105 | Stock | 1,800,000 | $80,676,000 | dollars as filed | |
| SPYRE THERAPEUTICS INC | 00773J202 | COM NEW | 2,388,245 | $78,238,906 | dollars as filed | |
| COGENT BIOSCIENCES INC | 19240Q201 | COM | 2,196,845 | $78,031,934 | dollars as filed | |
| ENLIVEN THERAPEUTICS INC COM | 29337E102 | Stock | 4,692,809 | $72,269,259 | dollars as filed | |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 2,565,000 | $69,665,400 | dollars as filed | |
| AMYLYX PHARMACEUTICALS INC | 03237H101 | COM | 5,650,000 | $68,252,000 | dollars as filed | |
| TERNS PHARMACEUTICALS INC COM | 880881107 | Stock | 1,475,000 | $59,590,000 | dollars as filed | |
| KYMERA THERAPEUTICS INC | 501575104 | COM | 750,000 | $58,357,500 | dollars as filed | |
| SOLENO THERAPEUTICS INC | 834203309 | COM | 1,200,000 | $55,560,000 | dollars as filed | |
| NUVALENT INC COM | 670703107 | Stock | 550,000 | $55,324,500 | dollars as filed | |
| ORUKA THERAPEUTICS INC COM | 687604108 | Stock | 1,753,054 | $53,135,067 | dollars as filed | |
| PHARVARIS NV | N69605108 | COMMON STOCK | 1,889,445 | $52,432,099 | dollars as filed | |
| NURIX THERAPEUTICS INC | 67080M103 | COMMON STOCK | 2,275,000 | $43,156,750 | dollars as filed | |
| PROTAGONIST THERAPEUTICS | 74366E102 | COM | 450,000 | $39,303,000 | dollars as filed | |
| ASSEMBLY BIOSCIENCES INC | 045396207 | COMMON STOCK | 1,000,000 | $34,010,000 | dollars as filed | |
| LB PHARMACEUTICALS INC | 50180M108 | COMMON STOCK | 1,500,000 | $33,390,000 | dollars as filed | |
| CYTOMX THERAPEUTICS INC | 23284F105 | COMMON STOCK | 7,692,300 | $32,769,198 | dollars as filed | |
| ALTO NEUROSCIENCE INC COM SHS | 02157Q109 | Stock | 1,823,196 | $32,452,889 | dollars as filed | |
| PALISADE BIO INC | 696389402 | COMMON STOCK | 11,445,000 | $26,895,750 | dollars as filed | |
| MIND MEDICINE MINDMED INC | 60255C885 | COM NEW | 2,000,000 | $26,780,000 | dollars as filed | |
| CENTESSA PHARMACEUTICALS PLC | 152309100 | SPONSORED ADS | 1,000,000 | $25,010,000 | dollars as filed | |
| PEPGEN INC COM | 713317105 | Stock | 3,400,000 | $22,134,000 | dollars as filed | |
| SAB BIOTHERAPEUTICS INC | 78397T202 | COMMON STOCK | 4,401,500 | $16,461,610 | dollars as filed | |
| REPLIMUNE GROUP INC | 76029N106 | COMMON STOCK | 1,425,000 | $13,851,000 | dollars as filed | |
| INHIBIKASE THERAPEUTICS INC | 45719W205 | COMMON STOCK | 5,397,488 | $11,064,850 | dollars as filed | |
| CONTINEUM THERAPEUTICS INC CL A | 21217B100 | Stock | 816,326 | $9,330,606 | dollars as filed | |
| AVALO THERAPEUTICS INC | 05338F306 | COMMON STOCK | 483,000 | $8,771,280 | dollars as filed | |
| RAPT THERAPEUTICS INC | 75382E208 | COM NEW | 250,000 | $8,467,500 | dollars as filed | |
| LeonaBio Inc | 04746L203 | COM | 464,398 | $3,515,493 | dollars as filed | |
| BRIGHT MINDS BIOSCIENCES INC | 10919W405 | COMMON STOCK | 18,851 | $1,471,132 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001831942-26-000004 | this filing | 2026-02-17 | acceptance time not in the bulk data set |