RA CAPITAL MANAGEMENT, L.P. in group RA CAPITAL MANAGEMENT, L.P. More: the full row for RA CAPITAL MANAGEMENT, L.P. 6,955,993 $117M 1.2% 0 13F-HR Timeline Group Siren, L.L.C. in group Siren, L.L.C. More: the full row for Siren, L.L.C. 5,216,969 $87.8M 2.62% 0 13F-HR Timeline Group Vestal Point Capital, LP More: the full row for Vestal Point Capital, LP 3,575,000 $60.2M 2.21% -1,525,000 13F-HR Timeline FMR LLC in group FMR LLC More: the full row for FMR LLC 3,347,223 $56.3M <0.01% +648,862 13F-HR Timeline Group T. Rowe Price Investment Management, In… More: the full row for T. Rowe Price Investment Management, Inc. 3,236,595 $54.5M 0.03% +2,771,868 13F-HR/A Timeline RED TREE MANAGEMENT, LLC More: the full row for RED TREE MANAGEMENT, LLC 3,170,509 $53.4M 48.94% 0 13F-HR Timeline TPG GP A, LLC in group TPG GP A, LLC More: the full row for TPG GP A, LLC 3,010,425 $50.7M 1.89% 0 13F-HR Timeline Group JANUS HENDERSON GROUP PLC in group Janus Henderson More: the full row for JANUS HENDERSON GROUP PLC 2,646,285 $44.5M 0.02% new 13F-HR Timeline Group Deep Track Capital, LP More: the full row for Deep Track Capital, LP 2,614,004 $44M 1% +187,347 13F-HR Timeline BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 2,528,451 $42.6M <0.01% +216,662 13F-HR Timeline Group Omega Fund Management, LLC More: the full row for Omega Fund Management, LLC 2,204,650 $37.1M 12.95% 0 13F-HR Timeline VANGUARD GROUP INC in group VANGUARD GROUP INC More: the full row for VANGUARD GROUP INC 2,186,150 $36.8M <0.01% -14,775 13F-HR Timeline Group Franklin Resources group of 2 filers holding More: the full row for Franklin Resources 1,918,787 $32.3M +1,594,466 Timeline STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 1,649,537 $27.8M <0.01% +1,059,260 13F-HR Timeline Group PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 1,559,535 $26.2M <0.01% -195,876 13F-HR Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 811,400 $13.7M <0.01% -19,808 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 772,258 $13M 0.01% new 13F-HR Timeline Group FIL Ltd in group FIL Ltd More: the full row for FIL Ltd 758,493 $12.8M 0.01% -45,260 13F-HR Timeline Group ACORN CAPITAL ADVISORS, LLC More: the full row for ACORN CAPITAL ADVISORS, LLC 643,382 $10.8M 3.67% 0 13F-HR Timeline Aisling Capital Management LP More: the full row for Aisling Capital Management LP 568,919 $9.57M 2% 0 13F-HR Timeline GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 552,331 $9.3M <0.01% +319,570 13F-HR/A Timeline Group MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 434,699 $7.32M 0.01% -580,193 13F-HR Timeline Group Rock Springs Capital Management LP More: the full row for Rock Springs Capital Management LP 429,095 $7.22M 0.37% +58,429 13F-HR Timeline Ensign Peak Advisors, Inc More: the full row for Ensign Peak Advisors, Inc 401,444 $6.76M 0.01% new 13F-HR/A Timeline NAN FUNG TRINITY (HK) LTD More: the full row for NAN FUNG TRINITY (HK) LTD 372,385 $6.27M 0.5% -12,500 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 335,682 $5.65M <0.01% -120,939 13F-HR Timeline Group ALGERT GLOBAL LLC More: the full row for ALGERT GLOBAL LLC 318,269 $5.36M 0.08% +300,679 13F-HR/A Timeline Palo Alto Investors LP More: the full row for Palo Alto Investors LP 298,575 $5.03M 0.7% new 13F-HR Timeline CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 272,145 $4.58M <0.01% -8,731 13F-HR Timeline Group DAFNA Capital Management LLC More: the full row for DAFNA Capital Management LLC 261,583 $4.4M 1.02% -55,418 13F-HR Timeline TD Asset Management Inc More: the full row for TD Asset Management Inc 244,626 $4.12M <0.01% +59,644 13F-HR Timeline NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 237,107 $3.99M <0.01% -23,759 13F-HR Timeline Group Woodline Partners LP More: the full row for Woodline Partners LP 232,690 $3.92M 0.02% -116,000 13F-HR Timeline ORBIMED ADVISORS LLC in group ORBIMED ADVISORS LLC More: the full row for ORBIMED ADVISORS LLC 209,100 $3.52M 0.07% new 13F-HR Timeline Group UBS Group AG group of 2 filers holding More: the full row for UBS Group AG 192,267 $3.24M +94,905 Timeline Hudson Bay Capital Management LP in group Hudson Bay Capital Management… More: the full row for Hudson Bay Capital Management LP 150,000 $2.52M 0.01% new 13F-HR Timeline Group D. E. Shaw & Co., Inc. in group D. E. Shaw & Co., Inc. More: the full row for D. E. Shaw & Co., Inc. 136,522 $2.3M <0.01% new 13F-HR Timeline Group DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 128,626 $2.16M <0.01% +1,171 13F-HR Timeline Group Napean Trading & Investment Co (Singapo… More: the full row for Napean Trading & Investment Co (Singapore) PTE Ltd 113,780 $1.91M 0.37% -162,162 13F-HR Timeline Atle Fund Management AB More: the full row for Atle Fund Management AB 111,363 $1.87M 0.6% -92,392 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 109,456 $1.84M <0.01% +9,428 13F-HR/A Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 103,241 $1.74M <0.01% +55,093 13F-HR Timeline Group Soleus Capital Management, L.P. More: the full row for Soleus Capital Management, L.P. 100,000 $1.68M 0.07% new 13F-HR Timeline TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 98,481 $1.66M <0.01% +3,243 13F-HR Timeline Group BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 95,901 $1.61M <0.01% +59,385 13F-HR Timeline Group MANUFACTURERS LIFE INSURANCE COMPANY, T… in group MANUFACTURERS LIFE INSURANCE … More: the full row for MANUFACTURERS LIFE INSURANCE COMPANY, THE 98,918 $1.6M <0.01% -27,884 13F-HR Timeline Group Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 88,677 $1.49M <0.01% +4,143 13F-HR Timeline Group JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 85,583 $1.44M <0.01% new 13F-HR Timeline Group CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 66,697 $1.12M <0.01% +66,041 13F-HR Timeline Group Mariner, LLC in group Mariner, LLC More: the full row for Mariner, LLC 64,562 $1.09M <0.01% +1,902 13F-HR Timeline Group Shay Capital LLC More: the full row for Shay Capital LLC 64,300 $1.08M 0.17% new 13F-HR Timeline Y-Intercept (Hong Kong) Ltd More: the full row for Y-Intercept (Hong Kong) Ltd 59,937 $1.01M 0.02% new 13F-HR Timeline Rafferty Asset Management, LLC More: the full row for Rafferty Asset Management, LLC 59,819 $1.01M <0.01% new 13F-HR Timeline Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 56,598 $953K <0.01% +17,472 13F-HR Timeline Group SCS Capital Management LLC More: the full row for SCS Capital Management LLC 53,430 $899K 0.01% 0 13F-HR Timeline HRT FINANCIAL LP More: the full row for HRT FINANCIAL LP 50,147 $843K <0.01% new 13F-HR Timeline ALPS ADVISORS INC in group ALPS ADVISORS INC More: the full row for ALPS ADVISORS INC 44,978 $757K <0.01% +18,600 13F-HR Timeline Group NORGES BANK More: the full row for NORGES BANK 42,889 $722K <0.01% new 13F-HR Timeline DIMENSIONAL FUND ADVISORS LP in group DIMENSIONAL FUND ADVISORS LP More: the full row for DIMENSIONAL FUND ADVISORS LP 40,934 $689K <0.01% new 13F-HR Timeline Group RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 40,583 $683K <0.01% -5,036 13F-HR Timeline Nuveen, LLC in group TIAA More: the full row for Nuveen, LLC 38,841 $654K <0.01% -5,596 13F-HR Timeline Group DARK FOREST CAPITAL MANAGEMENT LP More: the full row for DARK FOREST CAPITAL MANAGEMENT LP 37,636 $633K 0.03% new 13F-HR Timeline Trexquant Investment LP More: the full row for Trexquant Investment LP 37,094 $624K 0.01% -919 13F-HR Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 35,243 $593K <0.01% +9,319 13F-HR Timeline Group XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 34,067 $573K 0.02% -3,707 13F-HR Timeline Group Swiss National Bank More: the full row for Swiss National Bank 32,300 $544K <0.01% new 13F-HR Timeline SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 30,693 $517K <0.01% new 13F-HR Timeline Group Bleakley Financial Group, LLC More: the full row for Bleakley Financial Group, LLC 29,182 $491K 0.01% -1,296 13F-HR Timeline ALLIANCEBERNSTEIN L.P. More: the full row for ALLIANCEBERNSTEIN L.P. 29,110 $490K <0.01% -11,660 13F-HR Timeline TUDOR INVESTMENT CORP ET AL More: the full row for TUDOR INVESTMENT CORP ET AL 27,391 $461K <0.01% +8,661 13F-HR Timeline AMERICAN CENTURY COMPANIES INC in group AMERICAN CENTURY COMPANIES INC More: the full row for AMERICAN CENTURY COMPANIES INC 24,493 $412K <0.01% +13,816 13F-HR Timeline Group Caption Management, LLC More: the full row for Caption Management, LLC 23,000 $387K 0.02% new 13F-HR Timeline PROFUND ADVISORS LLC More: the full row for PROFUND ADVISORS LLC 22,177 $373K 0.01% new 13F-HR Timeline Creative Planning in group Creative Planning More: the full row for Creative Planning 21,834 $367K <0.01% +11,790 13F-HR Timeline Group MetLife Investment Management, LLC in group MetLife Investment Management… More: the full row for MetLife Investment Management, LLC 21,519 $362K <0.01% 0 13F-HR Timeline Group Invesco Ltd. in group Invesco Ltd. More: the full row for Invesco Ltd. 21,006 $354K <0.01% +3,595 13F-HR Timeline Group Jump Financial, LLC in group Jump Financial, LLC More: the full row for Jump Financial, LLC 20,988 $353K <0.01% new 13F-HR Timeline Group Mirae Asset Global Investments Co., Ltd. group of 2 filers holding More: the full row for Mirae Asset Global Investments Co., Ltd. 20,802 $348K +4,692 Timeline VOYA INVESTMENT MANAGEMENT LLC in group VOYA INVESTMENT MANAGEMENT LLC More: the full row for VOYA INVESTMENT MANAGEMENT LLC 18,195 $306K <0.01% new 13F-HR Timeline Group CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 17,158 $289K <0.01% +15,017 13F-HR Timeline GROUP ONE TRADING LLC More: the full row for GROUP ONE TRADING LLC 16,914 $285K 0.01% new 13F-HR Timeline JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 16,847 $284K <0.01% -8,088 13F-HR Timeline Group AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 16,032 $270K <0.01% +50 13F-HR Timeline Group Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 15,958 $269K <0.01% +12,802 13F-HR Timeline Group VARCOV Co. More: the full row for VARCOV Co. 15,653 $263K 0.1% 13F-HR Timeline Quantinno Capital Management LP More: the full row for Quantinno Capital Management LP 15,165 $255K <0.01% +4,588 13F-HR Timeline Virtus Investment Advisers, LLC in group Virtus Investment Advisers, L… More: the full row for Virtus Investment Advisers, LLC 14,395 $242K 0.07% +4,560 13F-HR Timeline Group LPL Financial LLC More: the full row for LPL Financial LLC 14,283 $240K <0.01% -14 13F-HR Timeline Ascent Group, LLC in group Ascent Group, LLC More: the full row for Ascent Group, LLC 14,151 $238K 0.01% +221 13F-HR Timeline Group Brevan Howard Capital Management LP in group Brevan Howard Capital Managem… More: the full row for Brevan Howard Capital Management LP 14,117 $238K <0.01% new 13F-HR Timeline Group INTECH INVESTMENT MANAGEMENT LLC More: the full row for INTECH INVESTMENT MANAGEMENT LLC 14,103 $237K <0.01% +65 13F-HR Timeline ADAR1 Capital Management, LLC in group ADAR1 Capital Management, LLC More: the full row for ADAR1 Capital Management, LLC 13,705 $231K 0.02% 0 13F-HR/A Timeline Group Graham Capital Management, L.P. More: the full row for Graham Capital Management, L.P. 13,116 $221K 0.01% new 13F-HR Timeline Orion Porfolio Solutions, LLC More: the full row for Orion Porfolio Solutions, LLC 11,278 $190K <0.01% -25 13F-HR Timeline LETKO, BROSSEAU & ASSOCIATES INC More: the full row for LETKO, BROSSEAU & ASSOCIATES INC 11,175 $188K <0.01% new 13F-HR Timeline Aquatic Capital Management LLC More: the full row for Aquatic Capital Management LLC 11,127 $187K 0.01% new 13F-HR Timeline SG Americas Securities, LLC More: the full row for SG Americas Securities, LLC 11,122 $187K <0.01% new 13F-HR Timeline VICTORY CAPITAL MANAGEMENT INC More: the full row for VICTORY CAPITAL MANAGEMENT INC 10,070 $169K <0.01% +160 13F-HR Timeline Police & Firemen's Retirement System of… More: the full row for Police & Firemen's Retirement System of New Jersey 9,836 $166K <0.01% 0 13F-HR Timeline China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 8,927 $150K 0.01% new 13F-HR Timeline NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 7,500 $126K <0.01% +3,500 13F-HR Timeline Caitong International Asset Management … More: the full row for Caitong International Asset Management Co., Ltd 5,775 $97.2K 0.02% +4,585 13F-HR/A Timeline Avanza Fonder AB More: the full row for Avanza Fonder AB 5,039 $84.8K <0.01% -4,332 13F-HR Timeline OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 4,494 $75.6K <0.01% +87 13F-HR Timeline Group SIMPLEX TRADING, LLC More: the full row for SIMPLEX TRADING, LLC 4,167 $70.1K <0.01% +3,159 13F-HR Timeline Larson Financial Group LLC More: the full row for Larson Financial Group LLC 3,559 $59.9K <0.01% -390 13F-HR Timeline KLP KAPITALFORVALTNING AS More: the full row for KLP KAPITALFORVALTNING AS 3,500 $58.9K <0.01% new 13F-HR Timeline Ameritas Investment Partners, Inc. in group Ameritas Investment Partners,… More: the full row for Ameritas Investment Partners, Inc. 2,893 $48.7K <0.01% -600 13F-HR Timeline Group Sterling Capital Management LLC More: the full row for Sterling Capital Management LLC 1,720 $28.9K <0.01% -506 13F-HR Timeline CWM, LLC in group CWM, LLC More: the full row for CWM, LLC 1,158 $19K <0.01% -197 13F-HR Timeline Group GAMMA Investing LLC More: the full row for GAMMA Investing LLC 1,125 $18.9K <0.01% -11 13F-HR Timeline GF FUND MANAGEMENT CO. LTD. More: the full row for GF FUND MANAGEMENT CO. LTD. 1,076 $18.1K <0.01% new 13F-HR Timeline ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 1,082 $18K <0.01% +671 13F-HR Timeline Group AMALGAMATED BANK More: the full row for AMALGAMATED BANK 989 $17K <0.01% +331 13F-HR Timeline Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 684 $11.5K <0.01% -1,117 13F-HR Timeline Group NISA INVESTMENT ADVISORS, LLC More: the full row for NISA INVESTMENT ADVISORS, LLC 570 $9.59K <0.01% +409 13F-HR Timeline PNC Financial Services Group, Inc. in group PNC Financial Services Group,… More: the full row for PNC Financial Services Group, Inc. 319 $5.37K <0.01% 0 13F-HR Timeline Group EverSource Wealth Advisors, LLC in group EverSource Wealth Advisors, L… More: the full row for EverSource Wealth Advisors, LLC 309 $5.2K <0.01% -60 13F-HR Timeline Group Smartleaf Asset Management LLC More: the full row for Smartleaf Asset Management LLC 274 $4.42K <0.01% new 13F-HR Timeline US BANCORP \DE\ in group US BANCORP \DE\ More: the full row for US BANCORP \DE\ 234 $3.94K <0.01% -1 13F-HR Timeline Group PRIVATE TRUST CO NA More: the full row for PRIVATE TRUST CO NA 225 $3.79K <0.01% 0 13F-HR Timeline Daiwa Securities Group Inc. in group Daiwa Securities Group Inc. More: the full row for Daiwa Securities Group Inc. 182 $3K <0.01% new 13F-HR Timeline Group Rockefeller Capital Management L.P. in group Rockefeller Capital Managemen… More: the full row for Rockefeller Capital Management L.P. 121 $2.04K <0.01% new 13F-HR/A Timeline Group Global Retirement Partners, LLC More: the full row for Global Retirement Partners, LLC 118 $1.99K <0.01% +13 13F-HR Timeline Versant Capital Management, Inc More: the full row for Versant Capital Management, Inc 108 $1.82K <0.01% +13 13F-HR Timeline Farther Finance Advisors, LLC More: the full row for Farther Finance Advisors, LLC 67 $1.13K <0.01% +52 13F-HR Timeline BELLEVUE ASSET MANAGEMENT, LLC More: the full row for BELLEVUE ASSET MANAGEMENT, LLC 61 $1.03K <0.01% new 13F-HR Timeline Allworth Financial LP More: the full row for Allworth Financial LP 53 $892 <0.01% +11 13F-HR Timeline MAI Capital Management More: the full row for MAI Capital Management 45 $758 <0.01% new 13F-HR Timeline CoreCap Advisors, LLC More: the full row for CoreCap Advisors, LLC 32 $539 <0.01% 0 13F-HR Timeline WPG Advisers, LLC More: the full row for WPG Advisers, LLC 26 $438 <0.01% new 13F-HR Timeline True Wealth Design, LLC More: the full row for True Wealth Design, LLC 23 $388 <0.01% 0 13F-HR Timeline COMERICA BANK More: the full row for COMERICA BANK 12 $202 <0.01% new 13F-HR Timeline Stone House Investment Management, LLC More: the full row for Stone House Investment Management, LLC 10 $168 <0.01% new 13F-HR Timeline Essential Partners LLC More: the full row for Essential Partners LLC 9 $151 <0.01% 0 13F-HR Timeline Arax Advisory Partners More: the full row for Arax Advisory Partners 3 $50 <0.01% -67 13F-HR Timeline Aster Capital Management (DIFC) Ltd More: the full row for Aster Capital Management (DIFC) Ltd 1 $17 <0.01% new 13F-HR Timeline