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Disclosery

APGE APOGEE THERAPEUTICS INC

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Stock (common)

181 managers (184 13F filers) reported a position in APGE shares at 2025-06-30, 57,837,560 shares in all. 37 filers opened a position and 22 filers sold out during the quarter.

Managers
181
13F filers
184
New
37
Added
55
Reduced
65
Sold out
22
Shares held by filers
57,837,560

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2025

Filers in the available 13F reports with a share position at 2025-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Venrock Adviser, LLC8,493,321$369M27.64%013F-HRTimeline
FMR LLCin group FMR LLC6,907,100$300M0.02%-586,52613F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…3,805,710$165M0.03%-1,680,04413F-HRTimelineGroup
RTW INVESTMENTS, LP2,712,097$118M1.68%013F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.2,562,539$111M<0.01%-348,29013F-HRTimelineGroup
Driehaus Capital Management LLC2,310,755$100M0.8%-28,80813F-HRTimeline
VANGUARD GROUP INCin group VANGUARD GROUP INC2,108,938$91.6M<0.01%+26,33213F-HRTimelineGroup
Fairmount Funds Management LLCin group Fairmount Funds Management LLC2,048,647$89M11.53%013F-HRTimelineGroup
BRAIDWELL LP1,478,512$64.2M2.2%-61,85013F-HRTimeline
ALLIANCEBERNSTEIN L.P.1,388,149$60.3M0.02%+107,19913F-HRTimeline
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…1,290,464$56M0.09%+563,46413F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP1,259,258$54.7M<0.01%-54,49213F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.1,230,377$53.4M0.13%+837,88913F-HRTimelineGroup
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC1,182,148$51.3M1.93%+59,38113F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO1,125,570$48.9M<0.01%+162,93913F-HRTimelineGroup
Paradigm Biocapital Advisors LPin group Paradigm Biocapital Advisors …958,630$41.6M1.78%-3,07713F-HRTimelineGroup
Woodline Partners LP870,208$37.8M0.2%-190,84513F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources852,531$37M0.01%-23,54513F-HRTimelineGroup
MERCER GLOBAL ADVISORS INC /ADV820,376$35.6M0.08%-819,80413F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC782,641$34M<0.01%-53,05413F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/760,844$33M<0.01%-61,00613F-HRTimeline
Affinity Asset Advisors, LLC691,899$30M4.44%-459,30013F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC659,186$28.6M<0.01%+368,48713F-HRTimelineGroup
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.642,357$27.9M0.46%+220,56113F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC608,822$26.4M0.01%+110,19713F-HR/ATimelineGroup
Siren, L.L.C.in group Siren, L.L.C.594,994$25.8M1.34%013F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson509,321$22.1M0.01%-1,284,51213F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/508,987$22.1M<0.01%+83,10713F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC495,659$21.5M0.02%+429,47713F-HRTimelineGroup
Polar Capital Holdings Plcin group Polar Capital Holdings Plc495,000$21.5M0.11%-55,00013F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY474,702$20.6M<0.01%-45,23713F-HRTimelineGroup
NOVO HOLDINGS A/S449,392$19.5M1.38%new13F-HRTimeline
First Turn Management, LLC311,490$13.5M2.52%+81,81513F-HRTimeline
FRONTIER CAPITAL MANAGEMENT CO LLC309,066$13.4M0.12%+200,24913F-HRTimeline
Commodore Capital LPin group Commodore Capital LP290,000$12.6M0.89%013F-HRTimelineGroup
JENNISON ASSOCIATES LLC270,366$11.7M0.01%-23,39113F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co266,384$11.6M<0.01%-5,49513F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP264,188$11.5M<0.01%-50,29013F-HRTimelineGroup
VICTORY CAPITAL MANAGEMENT INC254,770$11.1M0.01%+21,78713F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC245,133$10.6M0.01%-15,20213F-HRTimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC232,047$10.1M3.33%new13F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp201,151$8.74M<0.01%-13,08013F-HRTimelineGroup
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC200,000$8.69M0.44%013F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.194,528$8.45M0.01%+185,75213F-HRTimelineGroup
Capital World Investors193,895$8.42M<0.01%013F-HRTimeline
Blackstone Inc.in group Blackstone Inc.178,546$7.75M0.03%-5,20113F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding162,219$7.05M-575,416Timeline
Balyasny Asset Management L.P.in group Balyasny Asset Management158,635$6.89M0.02%+45,90513F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC156,108$6.78M<0.01%+59,78213F-HRTimelineGroup
Granahan Investment Management, LLC131,138$5.7M0.23%+22,79813F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …125,829$5.46M0.01%-1,37913F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding121,994$5.3M-197,841Timeline
SCHRODER INVESTMENT MANAGEMENT GROUP119,246$5.18M<0.01%+22,25413F-HRTimeline
ArrowMark Colorado Holdings LLC109,410$4.75M0.09%013F-HRTimeline
TD Asset Management Inc94,588$4.11M<0.01%-6,80013F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP90,568$3.93M<0.01%+78,96913F-HRTimelineGroup
PLATINUM INVESTMENT MANAGEMENT LTD86,512$3.76M0.25%-9,13413F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC85,183$3.7M0.11%new13F-HRTimeline
STEMPOINT CAPITAL LP84,466$3.67M1.18%new13F-HRTimeline
Nuveen, LLCin group TIAA83,291$3.62M<0.01%-27,56413F-HRTimelineGroup
Weiss Asset Management LPin group Weiss Asset Management LP82,302$3.57M0.06%new13F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
Sofinnova Investments, Inc.76,180$3.31M0.23%new13F-HRTimeline
KENNEDY CAPITAL MANAGEMENT LLC75,897$3.3M0.08%-2,50013F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …72,939$3.17M<0.01%-14,40813F-HRTimelineGroup
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC68,845$2.99M<0.01%+43,94013F-HRTimelineGroup
Avidity Partners Management LP65,000$2.82M0.57%new13F-HRTimeline
Capitolis Liquid Global Markets LLCin group CAPITOLIS LIQUID GLOBAL MARKE…62,800$2.73M0.02%new13F-HRTimelineGroup
Parkman Healthcare Partners LLC55,404$2.41M0.28%+8,74113F-HRTimeline
RHUMBLINE ADVISERS49,216$2.14M<0.01%-5,16913F-HRTimeline
HighVista Strategies LLC45,052$1.96M0.72%+1,86213F-HRTimeline
Swiss National Bank42,600$1.85M<0.01%-1,00013F-HRTimeline
Rafferty Asset Management, LLC42,211$1.83M0.01%-79013F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC41,100$1.78M<0.01%new13F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…38,697$1.68M<0.01%-31,64113F-HRTimelineGroup
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP37,622$1.63M<0.01%new13F-HRTimelineGroup
Blue Owl Capital Holdings LP35,000$1.52M0.49%new13F-HRTimeline
B Group, Inc.35,000$1.52M1.31%+5,00013F-HRTimeline
J. Goldman & Co LP34,605$1.5M0.05%new13F-HRTimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…33,085$1.44M0.02%new13F-HRTimelineGroup
COMERICA BANK29,469$1.28M<0.01%+14,10913F-HRTimeline
Polymer Capital Management (HK) LTD29,268$1.27M0.2%013F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc27,689$1.2M<0.01%+1,90713F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.26,866$1.17M<0.01%+2,55613F-HRTimelineGroup
ALPS ADVISORS INCin group ALPS ADVISORS INC24,850$1.08M0.01%-8,24613F-HRTimelineGroup
Erste Asset Management GmbHin group Erste Asset Management GmbH24,000$1.04M0.01%013F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\23,709$1.03M<0.01%-5,16013F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC22,928$996K<0.01%-38,43413F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…21,768$945K<0.01%+21,56413F-HRTimelineGroup
Moody Aldrich Partners LLC21,632$939K0.18%new13F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…21,386$929K<0.01%-79213F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding21,334$926K-4,702Timeline
MetLife Investment Management, LLCin group MetLife Investment Management…19,238$836K<0.01%-3,36713F-HRTimelineGroup
Lisanti Capital Growth, LLC18,410$800K0.22%new13F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC18,070$785K0.13%-86,78313F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN16,853$732K<0.01%-1,25113F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC16,070$698K0.01%-2,34713F-HRTimeline
Birchview Capital, LP16,000$695K0.69%+8,00013F-HRTimeline
NATIXIS ADVISORS, LLCin group Natixis Investment Managers15,031$653K<0.01%+1513F-HRTimelineGroup
WINTON GROUP Ltdin group WINTON GROUP Ltd14,617$635K0.03%new13F-HRTimelineGroup
China Universal Asset Management Co., L…14,248$619K0.06%+5,21613F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC12,445$540K<0.01%-8,98213F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd12,321$535K0.02%-4,86713F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD12,305$534K<0.01%+3,81413F-HRTimeline
Quadrature Capital Ltdin group Quadrature Capital Ltd11,829$513K0.01%new13F-HRTimelineGroup
TEACHERS RETIREMENT SYSTEM OF THE STATE…11,644$506K<0.01%013F-HRTimeline
DIADEMA PARTNERS LP10,572$459K0.29%-29,42813F-HRTimeline
FOX RUN MANAGEMENT, L.L.C.10,055$437K0.07%new13F-HRTimeline
Caption Management, LLC10,029$436K0.04%+7,61413F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND9,887$429K<0.01%-2,30013F-HR/ATimeline
STATE BOARD OF ADMINISTRATION OF FLORID…9,350$406K<0.01%013F-HRTimeline
Mariner, LLCin group Mariner, LLC9,267$402K<0.01%new13F-HRTimelineGroup
Creative Planningin group Creative Planning9,031$392K<0.01%new13F-HRTimelineGroup
PROFUND ADVISORS LLC8,981$390K0.01%-23413F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…8,960$389K<0.01%+7,75313F-HRTimeline
Glenmede Investment Management, LP8,857$385K<0.01%13F-HRTimeline
Handelsbanken Fonder AB8,500$369K<0.01%+1,00013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…8,419$366K0.01%+7,43413F-HRTimelineGroup
ProShare Advisors LLC8,265$359K<0.01%-1,97013F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC8,235$358K<0.01%-5,50713F-HRTimelineGroup
Global Endowment Management, LPin group Global Endowment Management, …7,797$339K0.05%013F-HRTimelineGroup
Police & Firemen's Retirement System of…7,349$319K<0.01%-77713F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC6,900$300K<0.01%+39813F-HRTimeline
Family Manage LLC6,860$298K0.05%013F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM6,488$282K<0.01%+3613F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS6,013$261K<0.01%-4713F-HRTimeline
Allostery Investments LP6,000$261K3.32%-104,00013F-HRTimeline
Aigen Investment Management, LP5,477$238K0.03%new13F-HRTimeline
OPTIMIZE FINANCIAL INC.5,284$229K0.14%new13F-HRTimeline
HRT FINANCIAL LP5,211$226K<0.01%new13F-HRTimeline
AlphaQuest LLC5,073$220K0.02%+3,93213F-HRTimeline
Allspring Global Investments Holdings, …in group Allspring Global Investments …4,931$218K<0.01%new13F-HRTimelineGroup
Legato Capital Management LLC4,720$205K0.02%new13F-HRTimeline
E Fund Management Co., Ltd.4,700$204K0.01%new13F-HRTimeline
KLP KAPITALFORVALTNING AS4,100$178K<0.01%-90013F-HRTimeline
Point72 Asia (Singapore) Pte. Ltd.3,813$166K0.03%+1,22913F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS3,649$158K<0.01%+94113F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…3,259$142K<0.01%-58013F-HRTimelineGroup
Persistent Asset Partners Ltd2,425$105K0.09%-6,75313F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…2,246$97.5K0.03%-1,45513F-HRTimelineGroup
Quarry LP1,930$83.8K0.02%new13F-HRTimeline
AMALGAMATED BANK1,312$57K<0.01%013F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,153$50.1K<0.01%013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC769$33.4K<0.01%+38313F-HRTimeline
ANTIPODES PARTNERS Ltd597$25.9K<0.01%+5513F-HRTimeline
T. Rowe Price Investment Management, In…464$21K<0.01%new13F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\422$18.3K<0.01%+37313F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.248$10.8K<0.01%+24613F-HR/ATimelineGroup
Versant Capital Management, Inc229$9.95K<0.01%-20513F-HRTimeline
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …202$9K<0.01%new13F-HRTimelineGroup
Larson Financial Group LLC194$8.43K<0.01%+16413F-HRTimeline
Caitong International Asset Management …188$8.16K0.01%new13F-HRTimeline
GROUP ONE TRADING LLC185$8.04K<0.01%-62013F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.166$7K<0.01%+3513F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…135$5.86K<0.01%+10813F-HRTimelineGroup
IFP Advisors, Inc0$5.3K<0.01%013F-HRTimelineAmount filed as zero, left out of ratios.
GAMMA Investing LLC121$5.25K<0.01%-2413F-HRTimeline
Washington Trust Advisors, Inc.96$4.17K<0.01%013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA85$4K<0.01%+3613F-HR/ATimelineGroup
Brooklyn Investment Group92$4K<0.01%-1,04213F-HR/ATimeline
ROTHSCHILD INVESTMENT LLC85$3.69K<0.01%013F-HRTimeline
Smartleaf Asset Management LLC79$3.43K<0.01%new13F-HRTimeline
Sterling Capital Management LLC77$3.34K<0.01%+3813F-HR/ATimeline
Leonteq Securities AG73$3.17K<0.01%013F-HRTimeline
CWM, LLCin group CWM, LLC80$3K<0.01%+6413F-HRTimelineGroup
Red Tortoise LLC69$3K<0.01%-2513F-HRTimeline
Farther Finance Advisors, LLC60$2.61K<0.01%-10113F-HRTimeline
Allworth Financial LP55$2.39K<0.01%new13F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…54$2.35K<0.01%+4713F-HRTimelineGroup
BESSEMER GROUP INCin group BESSEMER GROUP INC40$2K<0.01%new13F-HRTimelineGroup
BELLEVUE ASSET MANAGEMENT, LLC36$1.56K<0.01%013F-HRTimeline
SIGNATUREFD, LLC28$1.22K<0.01%+313F-HRTimeline
Arax Advisory Partners26$1.13K<0.01%013F-HRTimeline
Physician Wealth Advisors, Inc.18$782<0.01%new13F-HRTimeline
Rise Advisors, LLC16$695<0.01%-1513F-HRTimeline
Hughes Financial Services, LLC17$617<0.01%new13F-HRTimeline
Parkside Financial Bank & Trust10$435<0.01%013F-HRTimeline
Federation des caisses Desjardins du Qu…10$434<0.01%013F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC8$347<0.01%new13F-HRTimelineGroup
PRINCIPAL SECURITIES, INC.in group PRINCIPAL FINANCIAL GROUP INC5$217<0.01%new13F-HRTimelineGroup
Covestor Ltd3$00%013F-HRTimelineValue filed as zero, left out of ratios.
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.