13F-HR filed by Paradigm Biocapital Advisors LP
Paradigm Biocapital Advisors LP filed this 13F-HR for the quarter ended 2025-06-30, filed 2025-08-14, with 28 holding rows worth $2,342,122,068.
- Accession
- 0001855655-25-000010
- Filer
- CIK 1855655
- Filed
- 2025-08-14
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q2 2025
A holdings report, 28 entries on the cover page, a total value of $2,342,122,068 stated on the cover page (in dollars after the unit check, H1), rows summing to $2,342,122,068 with VALUE read as dollars as filed, 13F file number 028-21950. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| NUVALENT INC COM | 670703107 | Stock | 5,269,433 | $402,057,738 | dollars as filed | |
| ARCELLX INC COMMON STOCK | 03940C100 | Stock | 4,649,016 | $306,137,704 | dollars as filed | |
| MERUS N V | N5749R100 | COM | 4,281,954 | $225,230,780 | dollars as filed | |
| REVOLUTION MEDICINES INC COM | 76155X100 | Stock | 6,093,291 | $224,172,176 | dollars as filed | |
| TARSUS PHARMACEUTICALS INC | 87650L103 | COMMON STOCK | 2,976,099 | $120,561,770 | dollars as filed | |
| VAXCYTE INC COM | 92243G108 | Stock | 3,372,837 | $109,650,931 | dollars as filed | |
| BEONE MEDICINES LTD SPONSORED ADS | 07725L102 | ADR | 347,787 | $84,188,799 | dollars as filed | |
| EDGEWISE THERAPEUTICS INC | 28036F105 | COM | 6,142,344 | $80,526,130 | dollars as filed | |
| COGENT BIOSCIENCES INC | 19240Q201 | COM | 10,352,449 | $74,330,584 | dollars as filed | |
| JANUX THERAPEUTICS INC | 47103J105 | COM | 2,920,258 | $67,457,960 | dollars as filed | |
| CRINETICS PHARMACEUTICALS INC COM | 22663K107 | Stock | 2,343,553 | $67,400,584 | dollars as filed | |
| DISC MEDICINE INC COM | 254604101 | Stock | 1,210,971 | $64,133,024 | dollars as filed | |
| SCHOLAR ROCK HLDG CORP | 80706P103 | COM | 1,600,554 | $56,691,623 | dollars as filed | |
| LENZ THERAPEUTICS INC | 52635N103 | COM | 1,717,066 | $50,327,204 | dollars as filed | |
| BRIDGEBIO PHARMA INC | 10806X102 | COM | 965,764 | $41,701,690 | dollars as filed | |
| APOGEE THERAPEUTICS INC COM | 03770N101 | Stock | 958,630 | $41,633,301 | dollars as filed | |
| MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD | 61559X104 | Stock | 878,323 | $41,456,846 | dollars as filed | |
| ALKERMES PLC | G01767105 | SHS | 1,375,569 | $39,355,029 | dollars as filed | |
| VIRIDIAN THERAPEUTICS INC | 92790C104 | COM | 2,741,576 | $38,327,232 | dollars as filed | |
| AGIOS PHARMACEUTICALS INC | 00847X104 | COM | 1,142,511 | $37,999,916 | dollars as filed | |
| OCULAR THERAPEUTIX INC | 67576A100 | COM | 3,420,340 | $31,740,755 | dollars as filed | |
| OLEMA PHARMACEUTICALS INC | 68062P106 | COM | 6,764,172 | $28,815,373 | dollars as filed | |
| SPYRE THERAPEUTICS INC | 00773J202 | COM NEW | 1,870,445 | $28,000,562 | dollars as filed | |
| Y-mAbs Therapeutics Inc | 984241109 | Common Stock | 4,236,346 | $19,105,920 | dollars as filed | |
| PHARVARIS NV | N69605108 | COMMON STOCK | 1,062,911 | $18,707,234 | dollars as filed | |
| IMMATICS N.V | N44445109 | SHS | 3,144,157 | $16,915,565 | dollars as filed | |
| ERASCA INC COM | 29479A108 | Stock | 11,907,182 | $15,122,121 | dollars as filed | |
| CRESCENT BIOPHARMA INC | G2545C104 | COMMON STOCK | 642,721 | $10,373,517 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001855655-25-000010 | this filing | 2025-08-14 | acceptance time not in the bulk data set |