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Disclosery

APGE APOGEE THERAPEUTICS INC

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Stock (common)

167 managers (170 13F filers) reported a position in APGE shares at 2025-03-31, 61,488,129 shares in all. 33 filers opened a position and 21 filers sold out during the quarter.

Managers
167
13F filers
170
New
33
Added
50
Reduced
58
Sold out
21
Shares held by filers
61,488,129

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2025

Filers in the available 13F reports with a share position at 2025-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Venrock Adviser, LLC8,493,321$317M27%013F-HRTimeline
FMR LLCin group FMR LLC7,493,626$280M0.02%-5,75613F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…5,485,754$205M0.04%+968,39113F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.2,910,829$109M<0.01%-134,12913F-HRTimelineGroup
RTW INVESTMENTS, LP2,712,097$101M1.55%013F-HRTimeline
Driehaus Capital Management LLC2,339,563$87.4M0.84%-265,74713F-HRTimeline
VANGUARD GROUP INCin group VANGUARD GROUP INC2,082,606$77.8M<0.01%-14,99113F-HRTimelineGroup
Fairmount Funds Management LLCin group Fairmount Funds Management LLC2,048,647$76.5M11.87%013F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson1,793,833$71.3M0.04%+658,73313F-HRTimelineGroup
MERCER GLOBAL ADVISORS INC /ADV1,640,180$61.3M0.14%+920,07913F-HRTimeline
RA CAPITAL MANAGEMENT, L.P.in group RA CAPITAL MANAGEMENT, L.P.1,569,491$58.6M0.98%013F-HRTimelineGroup
BRAIDWELL LP1,540,362$57.5M2.02%013F-HRTimeline
STATE STREET CORPin group STATE STREET CORP1,313,750$49.1M<0.01%-153,36413F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.1,280,950$47.9M0.02%-74,23513F-HRTimeline
Affinity Asset Advisors, LLC1,151,199$43M6.73%+219,47113F-HRTimeline
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC1,122,767$41.9M1.49%+75,53513F-HR/ATimelineGroup
Woodline Partners LP1,061,053$39.6M0.26%+45,44513F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO962,631$36M<0.01%+925,37613F-HRTimelineGroup
Paradigm Biocapital Advisors LPin group Paradigm Biocapital Advisors …961,707$35.9M1.65%-322,05913F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources876,076$32.7M0.01%+9,88813F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC835,695$31.2M<0.01%+19,58213F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/821,850$30.7M<0.01%-230,74513F-HRTimeline
UBS Group AGgroup of 2 filers holding737,635$27.6M+164,088Timeline
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…727,000$27.2M0.05%+486,80013F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.594,994$22.2M1.25%-152,33113F-HR/ATimelineGroup
Polar Capital Holdings Plcin group Polar Capital Holdings Plc550,000$20.5M0.13%new13F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY519,939$19.4M<0.01%+310,40513F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC498,625$18.6M0.01%+21,86513F-HR/ATimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/425,880$15.9M<0.01%+320,34013F-HRTimelineGroup
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.421,796$15.8M0.27%-465,70113F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.392,488$14.7M0.04%+89,75313F-HR/ATimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding319,835$11.9M-18,147Timeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP314,478$11.7M<0.01%-12,81413F-HRTimelineGroup
JENNISON ASSOCIATES LLC293,757$11M0.01%-18,63413F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC290,699$10.9M<0.01%-117,32013F-HR/ATimelineGroup
Commodore Capital LPin group Commodore Capital LP290,000$10.8M0.8%013F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co271,879$10.2M<0.01%-5,61313F-HR/ATimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC260,335$9.73M0.01%+130,16413F-HRTimelineGroup
VICTORY CAPITAL MANAGEMENT INC232,983$8.7M0.01%+9,92113F-HRTimeline
First Turn Management, LLC229,675$8.58M1.73%-23,05013F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp214,231$8M<0.01%+103,40413F-HRTimelineGroup
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC200,000$7.47M0.41%+100,00013F-HRTimelineGroup
Capital World Investors193,895$7.24M<0.01%-11,20513F-HRTimeline
Blackstone Inc.in group Blackstone Inc.183,747$6.86M0.03%+103,74713F-HRTimelineGroup
VOLORIDGE INVESTMENT MANAGEMENT, LLC167,991$6.28M0.02%+126,88513F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …127,208$4.75M0.01%-16,74413F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management112,730$4.21M0.01%new13F-HRTimelineGroup
Nuveen, LLCin group TIAA110,855$4.14M<0.01%13F-HRTimelineGroup
Allostery Investments LP110,000$4.11M5.93%+10,00013F-HRTimeline
ArrowMark Colorado Holdings LLC109,410$4.09M0.07%013F-HRTimeline
FRONTIER CAPITAL MANAGEMENT CO LLC108,817$4.07M0.04%-63,89413F-HRTimeline
Granahan Investment Management, LLC108,340$4.05M0.2%+15,48613F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC104,853$3.92M0.75%+63,57913F-HRTimelineGroup
SCHRODER INVESTMENT MANAGEMENT GROUP96,992$3.85M<0.01%+38,52613F-HRTimeline
TD Asset Management Inc101,388$3.79M<0.01%-25,05813F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC96,326$3.6M<0.01%+90,61613F-HRTimelineGroup
PLATINUM INVESTMENT MANAGEMENT LTD95,646$3.57M0.21%013F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …87,347$3.26M<0.01%-60613F-HRTimelineGroup
KENNEDY CAPITAL MANAGEMENT LLC78,397$2.93M0.07%+6,09013F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…70,338$2.63M<0.01%+39,05013F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC66,182$2.47M<0.01%-6,54213F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC61,362$2.29M<0.01%+5,26013F-HRTimelineGroup
RHUMBLINE ADVISERS54,385$2.03M<0.01%+1,66513F-HR/ATimeline
Parkman Healthcare Partners LLC46,663$1.74M0.21%-38,33713F-HRTimeline
Swiss National Bank43,600$1.63M<0.01%-70013F-HRTimeline
HighVista Strategies LLC43,190$1.61M0.62%013F-HRTimeline
Rafferty Asset Management, LLC43,001$1.61M0.01%-14,67213F-HRTimeline
DIADEMA PARTNERS LP40,000$1.49M1.19%-10,62013F-HRTimeline
ALPS ADVISORS INCin group ALPS ADVISORS INC33,096$1.24M0.01%-3,31413F-HRTimelineGroup
B Group, Inc.30,000$1.12M0.97%+15,00013F-HRTimeline
DARK FOREST CAPITAL MANAGEMENT LP29,871$1.12M0.05%new13F-HRTimeline
Polymer Capital Management (HK) LTD29,268$1.09M0.19%new13F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\28,869$1.08M<0.01%-2,87013F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding26,036$981K+701Timeline
Legal & General Group Plcin group Legal & General Group Plc25,782$963K<0.01%-9113F-HRTimelineGroup
Erste Asset Management GmbHin group Erste Asset Management GmbH24,000$953K0.01%013F-HRTimelineGroup
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC24,905$930K<0.01%+37013F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.24,310$908K<0.01%+3,05413F-HRTimelineGroup
TWINBEECH CAPITAL LP24,298$908K0.02%new13F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…22,605$845K<0.01%-35513F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…22,178$829K<0.01%013F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC21,427$801K<0.01%-24,53313F-HR/ATimelineGroup
Corebridge Financial, Inc.in group Corebridge Financial, Inc.18,563$694K<0.01%-27613F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC18,417$688K0.01%+1,48313F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN18,104$676K<0.01%+39913F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd17,188$642K0.03%+10,84013F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC16,232$606K<0.01%-20,11213F-HR/ATimelineGroup
Soleus Capital Management, L.P.16,000$598K0.05%-54,00013F-HRTimeline
COMERICA BANK15,360$574K<0.01%-5,18013F-HRTimeline
NATIXIS ADVISORS, LLCin group Natixis Investment Managers15,016$561K<0.01%+23813F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC13,742$513K<0.01%+8,17413F-HR/ATimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND12,187$455K<0.01%013F-HR/ATimeline
TEACHERS RETIREMENT SYSTEM OF THE STATE…11,644$435K<0.01%013F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP11,599$433K<0.01%-64,25013F-HRTimelineGroup
Jain Global LLC11,586$433K0.01%new13F-HRTimeline
ProShare Advisors LLC10,235$382K<0.01%-2,57013F-HRTimeline
STATE BOARD OF ADMINISTRATION OF FLORID…9,350$349K<0.01%013F-HRTimeline
PROFUND ADVISORS LLC9,215$344K0.01%-2,22113F-HRTimeline
Persistent Asset Partners Ltd9,178$343K0.3%-8,76213F-HRTimeline
China Universal Asset Management Co., L…9,032$337K0.03%-51513F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.8,776$328K<0.01%-1,03713F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD8,491$317K<0.01%-4,90213F-HRTimeline
CIBC WORLD MARKETS CORP8,408$314K<0.01%new13F-HRTimeline
Police & Firemen's Retirement System of…8,126$304K<0.01%013F-HRTimeline
Birchview Capital, LP8,000$299K0.26%new13F-HRTimeline
Global Endowment Management, LPin group Global Endowment Management, …7,797$291K0.04%013F-HRTimelineGroup
Handelsbanken Fonder AB7,500$280K<0.01%013F-HRTimeline
Family Manage LLC6,860$256K0.04%-15313F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC6,502$243K<0.01%+1,59613F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM6,452$241K<0.01%-6513F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS6,060$226K<0.01%-62913F-HRTimeline
Engineers Gate Manager LP5,988$224K<0.01%new13F-HRTimeline
GLENMEDE TRUST CO NAin group GLENMEDE TRUST CO NA5,915$221K<0.01%-813F-HRTimelineGroup
KLP KAPITALFORVALTNING AS5,000$187K<0.01%013F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…3,839$143K<0.01%013F-HRTimelineGroup
Virtus Investment Advisers, LLCgroup of 2 filers holding3,701$138K+2,097Timeline
WEXFORD CAPITAL LP2,879$108K0.03%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS2,708$101K<0.01%-2,11613F-HRTimelineGroup
Point72 Asia (Singapore) Pte. Ltd.2,584$96.5K0.03%new13F-HRTimeline
Caption Management, LLC2,415$90.2K<0.01%new13F-HRTimeline
Point72 (DIFC) Ltd1,583$59.1K0.01%-20,60813F-HRTimeline
AMALGAMATED BANK1,312$49K<0.01%+6113F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…1,207$45.1K<0.01%013F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,153$43.1K<0.01%+20813F-HRTimeline
AlphaQuest LLC1,141$42.6K<0.01%new13F-HRTimeline
Brooklyn Investment Group1,134$42.4K0.01%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…985$36.8K<0.01%-5,30213F-HRTimelineGroup
Aster Capital Management (DIFC) Ltd1,050$33K0.01%+96013F-HRTimeline
GROUP ONE TRADING LLC805$30.1K<0.01%-51913F-HRTimeline
BI Asset Management Fondsmaeglerselskab…in group BI Asset Management Fondsmaeg…681$25K<0.01%new13F-HRTimelineGroup
ANTIPODES PARTNERS Ltd542$20.3K<0.01%new13F-HRTimeline
Versant Capital Management, Inc434$16.2K<0.01%new13F-HRTimeline
NISA INVESTMENT ADVISORS, LLC386$14.4K<0.01%-4213F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…204$7.62K<0.01%+1613F-HRTimelineGroup
Farther Finance Advisors, LLC161$5.73K<0.01%new13F-HRTimeline
GAMMA Investing LLC145$5.42K<0.01%-313F-HR/ATimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.131$5K<0.01%-4013F-HRTimelineGroup
Washington Trust Advisors, Inc.96$3.59K<0.01%013F-HRTimeline
Red Tortoise LLC94$3.51K<0.01%013F-HRTimeline
ROTHSCHILD INVESTMENT LLC85$3.18K<0.01%+6013F-HRTimeline
Leonteq Securities AG73$2.79K<0.01%new13F-HRTimeline
COLDSTREAM CAPITAL MANAGEMENT INC54$2.02K<0.01%new13F-HRTimeline
Lindbrook Capital, LLC54$2.02K<0.01%+4313F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA49$2K<0.01%-72713F-HR/ATimelineGroup
US BANCORP \DE\in group US BANCORP \DE\49$1.83K<0.01%+4413F-HRTimelineGroup
Sterling Capital Management LLC39$1.46K<0.01%013F-HRTimeline
BELLEVUE ASSET MANAGEMENT, LLC36$1.34K<0.01%013F-HRTimeline
Amundiin group Amundi35$1.23K<0.01%+2313F-HRTimelineGroup
Rise Advisors, LLC31$1.16K<0.01%new13F-HRTimeline
Larson Financial Group LLC30$1.12K<0.01%new13F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…27$1.01K<0.01%new13F-HRTimelineGroup
CWM, LLCin group CWM, LLC16$1K<0.01%-313F-HRTimelineGroup
Arax Advisory Partners26$972<0.01%new13F-HRTimeline
SIGNATUREFD, LLC25$934<0.01%new13F-HRTimeline
SIERRA OCEAN, LLC25$934<0.01%new13F-HRTimeline
Parkside Financial Bank & Trust10$374<0.01%new13F-HRTimeline
Stephens Consulting, LLC10$374<0.01%new13F-HRTimeline
Federation des caisses Desjardins du Qu…10$374<0.01%013F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…7$262<0.01%-413F-HRTimelineGroup
SouthState Bank Corpin group SouthState Bank Corp5$187<0.01%new13F-HRTimelineGroup
Quantbot Technologies LP5$187<0.01%new13F-HRTimeline
WealthTrak Capital Management LLC5$187<0.01%new13F-HRTimeline
IFP Advisors, Inc0$112<0.01%013F-HRTimelineAmount filed as zero, left out of ratios.
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.2$75<0.01%-1213F-HRTimelineGroup
True Wealth Design, LLC1$38<0.01%new13F-HRTimeline
Covestor Ltd3$00%013F-HRTimelineValue filed as zero, left out of ratios.
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.