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Disclosery

VRTX VERTEX PHARMACEUTICALS INC

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COM (common), issuer CIK 875320

1,650 managers (1,700 13F filers) reported a position in VRTX shares at 2026-03-31, 237,778,310 shares in all. 127 filers opened a position and 106 filers sold out during the quarter.

Managers
1,650
13F filers
1,700
New
127
Added
684
Reduced
600
Sold out
106
Shares held by filers
237,778,310

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2026

Filers in the available 13F reports with a share position at 2026-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
O'SHAUGHNESSY ASSET MANAGEMENT, LLC61,867$27.6M0.14%+14,62213F-HRTimeline
OFI INVEST ASSET MANAGEMENT69,233$26.8M0.35%+10913F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC59,954$26.8M0.05%-30,52913F-HRTimelineGroup
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCH…59,167$26.4M0.13%+15113F-HRTimeline
Hardman Johnston Global Advisors LLC58,357$26.1M1.24%-5,44913F-HRTimeline
Allianz SEgroup of 2 filers holding58,260$26M-3,197Timeline
NISA INVESTMENT ADVISORS, LLC58,183$26M0.1%+1,58913F-HRTimeline
FOSTER DYKEMA CABOT & PARTNERS, LLC57,792$25.8M1.64%-55213F-HRTimeline
MOODY LYNN LIEBERSON & WALKER, LLC57,640$25.7M1.44%+2,64813F-HRTimeline
SG Americas Securities, LLC56,982$25.4M0.03%-58,91713F-HRTimeline
BEACON INVESTMENT ADVISORY SERVICES, IN…56,104$25.1M1.04%-17,98913F-HRTimeline
ATWOOD & PALMER INC55,753$24.9M1.4%+36113F-HRTimeline
Smith Group Asset Management, LLC55,746$24.9M1.27%+3,69513F-HRTimeline
Edgemoor Investment Advisors, Inc.55,415$24.7M1.95%+57613F-HRTimeline
PINEBRIDGE INVESTMENTS LLC55,100$24.6M0.21%+52,19913F-HRTimeline
ZACKS INVESTMENT MANAGEMENT55,082$24.6M0.2%-1,54413F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC54,972$24.5M0.03%+82913F-HRTimeline
Reynders McVeigh Capital Management, LLC54,664$24.4M1.23%+75913F-HRTimeline
Rafferty Asset Management, LLC54,572$24.4M0.1%-13,51013F-HRTimeline
Retirement Systems of Alabama53,938$24.1M0.08%-3813F-HRTimeline
AMALGAMATED BANK53,269$23.8M0.18%-1,85113F-HRTimeline
Rakuten Group, Inc.group of 2 filers holding52,710$23.4M+5,504Timeline
CULLINAN ASSOCIATES INC51,762$23.1M1.87%+45013F-HRTimeline
Hemenway Trust Co LLC51,499$23M1.85%+48213F-HRTimeline
DAVIDSON INVESTMENT ADVISORS51,222$22.9M0.99%-13,00513F-HR/ATimeline
IFM Investors Pty Ltd51,070$22.8M0.19%+1,29013F-HRTimeline
Caisse de depot et placement du Quebec50,917$22.7M0.04%-62,85113F-HRTimeline
VALLEY WEALTH MANAGERS, INC.in group VALLEY WEALTH MANAGERS, INC.50,139$22.4M1.44%-81213F-HRTimelineGroup
CITIZENS FINANCIAL GROUP INC/RIin group CITIZENS FINANCIAL GROUP INC/…49,824$22.2M0.31%+6,42113F-HRTimelineGroup
BI Asset Management Fondsmaeglerselskab…in group BI Asset Management Fondsmaeg…49,531$22.1M0.23%+39,00513F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding49,410$22.1M-63,875Timeline
Sanctuary Advisors, LLC49,360$22M0.12%-44413F-HRTimeline
PensionDanmark Pensionsforsikringsaktie…49,204$22M0.21%-17713F-HRTimeline
USS Investment Management Ltd47,128$21M0.08%+1,73513F-HRTimeline
Wealthfront Advisers LLC46,395$20.7M0.05%+3,22613F-HRTimeline
C WorldWide Group Holding A/Sin group C WorldWide Group Holding A/S46,057$20.6M0.44%013F-HRTimelineGroup
Skandinaviska Enskilda Banken AB (publ)46,000$20.5M0.47%-128,46613F-HRTimeline
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…45,000$20.1M0.12%-119,51813F-HRTimelineGroup
MARTINGALE ASSET MANAGEMENT L P44,750$20M0.5%+1,52913F-HRTimeline
Zurich Insurance Group Ltd/FIin group Zurich Insurance Group Ltd/FI44,618$19.9M0.16%-4,08113F-HRTimelineGroup
Pathstone Holdings, LLCin group Pathstone Holdings, LLC44,262$19.8M0.08%-1,34213F-HRTimelineGroup
W.G. Shaheen & Associates DBA Whitney &…44,117$19.7M1.64%-4713F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.43,972$19.6M0.03%+22013F-HRTimelineGroup
China Universal Asset Management Co., L…43,902$19.6M1.48%-4,14513F-HRTimeline
Varma Mutual Pension Insurance Co43,626$19.5M0.11%+3,00013F-HR/ATimeline
Lido Advisors, LLCin group Lido Advisors, LLC43,511$19.4M0.08%-10,08613F-HRTimelineGroup
Rhenman & Partners Asset Management AB43,485$19.4M2.4%+9,23013F-HRTimeline
Empowered Funds, LLC41,737$18.6M0.12%+26,93113F-HR/ATimeline
Gradient Investments LLCin group Gradient Investments LLC41,736$18.6M0.29%-1,85913F-HRTimelineGroup
Utah Retirement Systems41,265$18.4M0.19%-1,22513F-HRTimeline
Public Sector Pension Investment Board41,177$18.4M0.06%+8,32613F-HRTimeline
BANCO BILBAO VIZCAYA ARGENTARIA, S.A.40,778$18.1M0.13%-53,05913F-HRTimeline
Illinois Municipal Retirement Fund40,573$18.1M0.23%-6,21313F-HRTimeline
Tweedy, Browne Co LLC40,387$18M1.43%+1,23913F-HRTimeline
CAPITAL GROUP INVESTMENT MANAGEMENT PTE…group of 2 filers holding40,310$18M-4,407Timeline
MACQUARIE GROUP LTDin group MACQUARIE GROUP LTD40,236$18M0.11%-4,50013F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management40,137$17.9M0.04%-73,35113F-HRTimelineGroup
Integral Health Asset Management, LLC40,000$17.9M0.95%new13F-HRTimeline
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC39,547$17.7M0.06%-18813F-HRTimeline
FLPUTNAM INVESTMENT MANAGEMENT CO39,498$17.6M0.26%+2,70713F-HRTimeline
OSSIAM39,357$17.6M0.31%+21,76313F-HRTimeline
Police & Firemen's Retirement System of…39,061$17.4M0.15%-41213F-HRTimeline
WEALTH ENHANCEMENT ADVISORY SERVICES, L…40,668$17.4M0.04%-40,57813F-HRTimeline
Apollon Wealth Management, LLCin group Apollon Wealth Management, LLC38,595$17.2M0.28%+9,40013F-HRTimelineGroup
SEGALL BRYANT & HAMILL, LLC38,073$17M0.24%-1,74613F-HR/ATimeline
New York Life Investment Management LLCin group New York Life Investment Mana…38,069$17M0.14%+1,25113F-HRTimelineGroup
BAILARD, INC.37,862$16.9M0.39%+3,88713F-HRTimeline
Aristotle Atlantic Partners, LLCin group ARISTOTLE INVESTMENT SERVICES…37,532$16.8M0.78%-85913F-HRTimelineGroup
TEACHERS RETIREMENT SYSTEM OF THE STATE…36,725$16.4M0.13%-3,59813F-HRTimeline
SHELTON CAPITAL MANAGEMENT36,379$16.2M0.36%-86213F-HRTimeline
CAXTON ASSOCIATES LLP36,026$16.1M0.37%new13F-HRTimeline
Y-Intercept (Hong Kong) Ltd35,829$16M0.3%new13F-HRTimeline
BANK OF NOVA SCOTIAin group BANK OF NOVA SCOTIA35,361$15.8M0.03%-62,55913F-HRTimelineGroup
Galvin, Gaustad & Stein, LLC35,233$15.7M1.26%+92413F-HRTimeline
FIDEURAM - INTESA SANPAOLO PRIVATE BANK…34,991$15.6M0.55%+3,71013F-HRTimeline
BRITISH COLUMBIA INVESTMENT MANAGEMENT …34,971$15.6M0.09%-10,52513F-HRTimeline
MCRAE CAPITAL MANAGEMENT INC34,123$15.2M3.16%-1,43513F-HRTimeline
Vestcor Inc34,019$15.2M0.42%-2,67113F-HRTimeline
Ilmarinen Mutual Pension Insurance Co33,800$15.1M0.12%-5,00013F-HRTimeline
MML INVESTORS SERVICES, LLC33,419$14.9M0.04%-4,58513F-HRTimeline
State of Alaska, Department of Revenue33,180$14.8M0.16%+26513F-HRTimeline
CAPTRUST FINANCIAL ADVISORS32,092$14.3M0.03%+18,28813F-HRTimeline
Elo Mutual Pension Insurance Co31,378$14M0.23%-23513F-HRTimeline
Fisher Asset Management, LLC31,158$13.9M<0.01%+5,94013F-HRTimeline
iA Global Asset Management Inc.30,915$13.8M0.2%-6,77013F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC30,823$13.8M0.01%-334,84113F-HRTimelineGroup
Walleye Capital LLCgroup of 2 filers holding30,752$13.7M+2,439Timeline
Foster Victor Wealth Advisors, LLC30,754$13.7M0.78%-2,17513F-HRTimeline
BARLOW WEALTH PARTNERS, LLC30,411$13.4M1.49%+32413F-HRTimeline
Caprock Group, LLC30,007$13.4M0.33%+98413F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\29,781$13.3M0.02%-6913F-HRTimelineGroup
Americana Partners, LLC29,773$13.3M0.35%+2,64013F-HRTimeline
Louisiana State Employees Retirement Sy…29,600$13.2M0.23%-40013F-HRTimeline
Osmosis Investment Management UK Ltd29,580$13.2M0.35%-10,71413F-HRTimeline
AIA Group Ltdin group AIA Group Ltd29,522$13.2M0.19%-4,29913F-HRTimelineGroup
HUNTINGTON NATIONAL BANKin group HUNTINGTON NATIONAL BANK29,123$13M0.07%-3,87613F-HRTimelineGroup
OREGON PUBLIC EMPLOYEES RETIREMENT FUND29,083$13M0.17%+3913F-HRTimeline
MassMutual Private Wealth & Trust, FSB28,726$12.8M0.35%+81213F-HRTimeline
BANQUE PICTET & CIE SA28,550$12.7M0.15%+4,22213F-HRTimeline
CIBC WORLD MARKET INC.28,078$12.5M0.02%+19,94513F-HRTimeline
Avanza Fonder AB27,647$12.3M0.34%+6213F-HRTimeline
Shelter Mutual Insurance Coin group Shelter Mutual Insurance Co27,600$12.3M2.74%013F-HRTimelineGroup
Madison Asset Management, LLCin group Madison Asset Management, LLC27,387$12.2M0.15%+10,95213F-HRTimelineGroup
Atria Investments, Inc27,342$12.2M0.14%-91913F-HRTimeline
Bogart Wealth, LLC27,196$12.1M0.47%+1913F-HRTimeline
IEQ CAPITAL, LLC27,175$12.1M0.06%+4,65113F-HRTimeline
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCin group MUTUAL OF AMERICA CAPITAL MAN…26,967$12M0.14%-23013F-HRTimelineGroup
NORDEA INVESTMENT MANAGEMENT ABin group NORDEA INVESTMENT MANAGEMENT …27,171$12M0.01%-419,99813F-HRTimelineGroup
HRT FINANCIAL LP26,790$12M0.03%new13F-HRTimeline
ASR Vermogensbeheer N.V.26,691$11.9M0.14%+63213F-HRTimeline
FAGAN ASSOCIATES, INC.26,553$11.9M1.65%-1313F-HRTimeline
OP Asset Management Ltd26,189$11.7M0.12%-2,26313F-HR/ATimeline
BENDER ROBERT & ASSOCIATES26,171$11.7M2.8%-29213F-HRTimeline
Danica Pension, Livsforsikringsaktiesel…26,126$11.7M0.22%new13F-HRTimeline
CCM INVESTMENT ADVISERS LLC25,894$11.6M1.11%-35513F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC25,868$11.5M0.02%+3,65813F-HRTimelineGroup
LVM CAPITAL MANAGEMENT LTD/MI25,830$11.5M1.09%+5513F-HRTimeline
Biondo Investment Advisors, LLC25,315$11.3M1.45%+17513F-HRTimeline
Norinchukin Bank, Thein group Norinchukin Bank, The25,049$11.2M0.13%+84613F-HRTimelineGroup
Atle Fund Management AB22,984$11.2M3.61%013F-HRTimeline
Longaeva Partners L.P.24,935$11.1M0.54%new13F-HRTimeline
Washington Trust Bank24,923$11.1M0.82%-4,91613F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
Horizon Investments, LLC24,435$10.9M0.12%+13,06013F-HRTimeline
Advisors Asset Management, Inc.24,300$10.9M0.18%-41313F-HRTimeline
Andra AP-fonden23,903$10.7M0.13%-12,03713F-HRTimeline
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.23,810$10.6M0.13%-7,56213F-HRTimelineGroup
Kestra Advisory Services, LLCgroup of 3 filers holding23,625$10.5M-1,902Timeline
Heirloom Wealth Management23,458$10.5M1.89%+3,25913F-HRTimeline
&PARTNERS23,387$10.5M0.05%+1,24913F-HRTimeline
YOUSIF CAPITAL MANAGEMENT, LLC23,367$10.4M0.12%-93713F-HRTimeline
Telos Capital Management, Inc.23,234$10.4M0.99%+85813F-HRTimeline
PROFUND ADVISORS LLC23,137$10.3M0.38%-5,68113F-HRTimeline
Waverly Advisors, LLC23,055$10.3M0.08%+32313F-HRTimeline
CARY STREET PARTNERS ASSET MANAGEMENT L…group of 2 filers holding23,035$10.3M+85Timeline
KENNEDY CAPITAL MANAGEMENT LLC22,994$10.3M0.22%+58013F-HRTimeline
MERCER GLOBAL ADVISORS INC /ADV22,762$10.2M0.02%-1,06013F-HRTimeline
ExodusPoint Capital Management, LP22,403$10M0.1%new13F-HRTimeline
Diversify Advisory Services, LLCgroup of 2 filers holding23,213$9.82M+4,396Timeline
GRANDFIELD & DODD, LLC21,704$9.69M0.55%+47313F-HRTimeline
FIL Ltdin group FIL Ltd21,623$9.66M0.01%+11,82013F-HRTimelineGroup
OPPENHEIMER ASSET MANAGEMENT INC.group of 2 filers holding21,610$9.65M+618Timeline
EXENCIAL WEALTH ADVISORS, LLC21,598$9.64M0.3%-78413F-HRTimeline
PINNACLE ASSOCIATES LTD21,590$9.64M0.12%-3,64813F-HRTimeline
ALLSTATE CORPin group ALLSTATE CORP21,523$9.61M0.1%+2,42813F-HRTimelineGroup
Eurizon SLJ Capital Ltd21,523$9.54M4.54%-2,63313F-HRTimeline
EULAV Asset Management21,000$9.38M0.3%-1,00013F-HRTimeline
CAMDEN NATIONAL BANK20,907$9.34M1.26%-6113F-HRTimeline
Gotham Asset Management, LLC20,887$9.33M0.03%-62413F-HRTimeline
Modera Wealth Management, LLC20,685$9.24M0.11%-59013F-HRTimeline
GW HENSSLER & ASSOCIATES LTD20,640$9.22M0.43%+1,80613F-HRTimeline
AIMZ Investment Advisors, LLC19,956$8.91M2.75%-30513F-HRTimeline
QRG CAPITAL MANAGEMENT, INC.19,900$8.89M0.09%+1,50413F-HRTimeline
Fiduciary Trust Coin group Fiduciary Trust Co19,876$8.88M0.1%-15613F-HRTimelineGroup
LMR Partners LLPin group LMR Partners LLP19,853$8.87M0.08%+3,38513F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC19,713$8.8M0.09%-8,81713F-HRTimeline
UniSuper Management Pty Ltd19,658$8.78M0.06%-33413F-HRTimeline
Gulf International Bank (UK) Ltd19,636$8.77M0.2%+6,72013F-HRTimeline
Investment Management Corp of Ontario19,562$8.74M0.11%-2,73813F-HRTimeline
Harvest Fund Management Co., Ltdin group Harvest Fund Management Co., …19,486$8.7M0.37%-34,71213F-HRTimelineGroup
Pinnacle Financial Partners, Inc.in group Pinnacle Financial Partners, …19,226$8.59M0.07%+63813F-HRTimelineGroup
SAPIENT CAPITAL LLC18,992$8.48M0.13%-15,33213F-HR/ATimeline
OMERS ADMINISTRATION Corp18,797$8.39M0.05%+3,31813F-HRTimeline
Broderick Brian C18,656$8.33M1.54%+1,45413F-HRTimeline
Azimuth Capital Investment Management L…18,656$8.33M0.31%-8613F-HRTimeline
Ethic Inc.17,896$7.99M0.13%+1,91313F-HRTimeline
Beacon Pointe Advisors, LLC17,894$7.99M0.04%+4,39213F-HRTimeline
Steward Partners Investment Advisory, L…17,863$7.98M0.04%+49913F-HRTimeline
HANTZ FINANCIAL SERVICES, INC.17,807$7.95M0.12%+10,61613F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
SIG BROKERAGE, LP17,605$7.86M2.22%-3,25913F-HRTimeline
PRUDENTIAL PLCin group PRUDENTIAL PLC17,526$7.83M0.05%+1,75513F-HRTimelineGroup
STRATEGIC PLANNING GROUP, LLC17,389$7.77M1.09%new13F-HRTimeline
Bleakley Financial Group, LLC17,226$7.69M0.12%+1,63213F-HRTimeline
Boston Common Asset Management, LLC17,205$7.68M0.49%+1,12413F-HRTimeline
NewEdge Advisors, LLC17,146$7.66M0.03%-18913F-HR/ATimeline
NORTHWESTERN MUTUAL INVESTMENT MANAGEME…group of 2 filers holding16,983$7.58M+576Timeline
Third View Private Wealth, LLC16,901$7.55M1.03%+1,18413F-HRTimeline
CAPITOLIS LIQUID GLOBAL MARKETS LLCin group CAPITOLIS LIQUID GLOBAL MARKE…16,806$7.5M0.05%13F-HRTimelineGroup
Trifecta Capital Advisors, LLC16,757$7.48M1.16%+26013F-HRTimeline
SOMERVILLE KURT F16,735$7.47M1.97%-6,59213F-HRTimeline
Cullen/Frost Bankers, Inc.in group Cullen/Frost Bankers, Inc.16,568$7.4M0.08%+15,97813F-HRTimelineGroup
BLAIR WILLIAM & CO/IL16,541$7.39M0.02%+45113F-HRTimeline
Fulcrum Capital LLC16,496$7.37M1.6%-12013F-HRTimeline
LEUTHOLD GROUP, LLC16,455$7.35M0.78%+4813F-HRTimeline
SILVERCREST ASSET MANAGEMENT GROUP LLC16,358$7.3M0.05%+33013F-HRTimeline
NLB Skladi, upravljanje premozenja, d.o…16,303$7.28M0.35%+1,15213F-HRTimeline
Vident Advisory, LLCin group Vident Advisory, LLC16,063$7.17M0.06%+2,37813F-HRTimelineGroup
Federation des caisses Desjardins du Qu…15,955$7.12M0.03%+2,93913F-HRTimeline
Cambridge Investment Research Advisors,…15,955$7.12M0.02%+1,59813F-HRTimeline
Allworth Financial LP15,803$7.06M0.03%+1,76713F-HRTimeline
ANDERSON HOAGLAND & CO15,734$7.03M0.6%013F-HRTimeline
Baldwin Investment Management, LLC15,662$6.99M0.82%+10813F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd15,632$6.98M0.12%new13F-HRTimelineGroup
NIA IMPACT ADVISORS, LLC15,490$6.92M3.08%-2,14813F-HRTimeline
PUZO MICHAEL J15,414$6.88M2%+4313F-HRTimeline
Torray Investment Partners LLC15,386$6.87M1.01%-8013F-HRTimeline
MIZUHO SECURITIES USA LLCin group MIZUHO FINANCIAL GROUP INC15,355$6.86M0.16%-3,11913F-HRTimelineGroup
Generali Asset Management SPA SGR15,300$6.83M0.14%-3,23813F-HRTimeline
Callan Family Office, LLC15,262$6.82M0.15%+82213F-HRTimeline
Trexquant Investment LP15,171$6.77M0.05%-30,88213F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC15,075$6.73M0.4%+1,35913F-HRTimelineGroup