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Disclosery

PLRX PLIANT THERAPEUTICS INC

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COM (common), issuer CIK 1746473

97 managers (99 13F filers) reported a position in PLRX shares at 2025-09-30, 50,407,728 shares in all. 12 filers opened a position and 26 filers sold out during the quarter.

Managers
97
13F filers
99
New
12
Added
22
Reduced
42
Sold out
26
Shares held by filers
50,407,728

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC6,003,446$8.89M0.34%+3,44613F-HRTimelineGroup
Woodline Partners LP4,504,817$6.67M0.03%+2,156,29113F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.4,338,394$6.42M0.01%new13F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY3,507,288$5.19M<0.01%-246,32513F-HR/ATimelineGroup
Blue Owl Capital Holdings LP2,969,199$4.39M1.36%013F-HRTimeline
VANGUARD GROUP INCgroup of 2 filers holding2,810,681$4.16M-227,207Timeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC2,369,542$3.5M0.01%+739,12913F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC2,339,468$3.46M<0.01%-16,43113F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO2,130,489$3.15M<0.01%+172,05613F-HR/ATimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding1,855,755$2.75M+1,122,397Timeline
Redmile Group, LLCin group Redmile Group, LLC1,591,695$2.36M0.23%-40,88213F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.1,420,863$2.1M<0.01%-709,65613F-HRTimelineGroup
UBS Group AGin group UBS Group AG1,322,017$1.96M<0.01%-1,324,53913F-HRTimelineGroup
Peapod Lane Capital LLC1,097,028$1.62M1.45%+203,29813F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC1,011,802$1.5M<0.01%+811,85413F-HRTimeline
GREAT POINT PARTNERS LLC850,000$1.26M0.53%013F-HRTimeline
Eversept Partners, LP824,594$1.22M0.09%new13F-HRTimeline
Monaco Asset Management SAM822,693$1.22M0.45%+120,30013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/708,056$1.05M<0.01%+227,52613F-HR/ATimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC587,409$870K<0.01%+4,82313F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC555,076$822K<0.01%-41,62213F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC537,337$795K<0.01%-313,13713F-HRTimelineGroup
BESSEMER GROUP INCin group BESSEMER GROUP INC532,079$787K<0.01%-3913F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd466,984$691K0.04%+37,97413F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC380,327$563K<0.01%+56,91513F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC369,556$547K<0.01%+356,67013F-HR/ATimelineGroup
JACOBS LEVY EQUITY MANAGEMENT, INC367,113$543K<0.01%new13F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP299,461$443K<0.01%new13F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO297,291$440K<0.01%013F-HRTimelineGroup
Stonepine Capital Management, LLC289,237$428K0.35%new13F-HRTimeline
ArrowMark Colorado Holdings LLC281,189$416K0.01%013F-HRTimeline
STATE STREET CORPin group STATE STREET CORP253,834$376K<0.01%013F-HRTimelineGroup
HighMark Wealth Management LLC219,000$324K0.14%+78,00013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS182,356$270K<0.01%+27,66513F-HRTimelineGroup
GSA CAPITAL PARTNERS LLP160,884$238K0.02%+146,74213F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP151,673$225K<0.01%-164,21413F-HRTimelineGroup
Voleon Capital Management LP149,041$221K0.01%new13F-HRTimeline
RICE HALL JAMES & ASSOCIATES, LLC144,843$214K0.01%-16,40513F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP136,500$202K<0.01%-28,94013F-HRTimelineGroup
TORNO CAPITAL, LLC130,916$194K0.03%new13F-HR/ATimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.125,376$186K<0.01%+115,26213F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.107,096$159K<0.01%+33,60213F-HRTimelineGroup
ALGERT GLOBAL LLC104,382$154K<0.01%+15,69213F-HR/ATimeline
Bond & Devick Financial Network, Inc.100,160$148K0.04%013F-HRTimeline
Hennion & Walsh Asset Management, Inc.98,034$145K0.01%-1,78513F-HRTimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC82,300$122K<0.01%013F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…73,954$109K<0.01%-96,03213F-HRTimelineGroup
Rangeley Capital, LLC60,220$89.1K0.08%013F-HRTimeline
Catalyst Funds Management Pty Ltd59,539$88.1K0.01%+25,52413F-HRTimeline
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.55,296$81.8K<0.01%-30,12513F-HRTimelineGroup
Cubist Systematic Strategies, LLC54,367$80.5K<0.01%-213,98613F-HRTimeline
Qube Research & Technologies Ltd49,515$73.3K<0.01%-102,14713F-HRTimeline
DekaBank Deutsche Girozentrale40,000$57K<0.01%013F-HRTimeline
Quadrature Capital Ltdin group Quadrature Capital Ltd37,595$55.5K<0.01%-23,62613F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC33,842$50.1K<0.01%-124,00213F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL29,729$44K<0.01%013F-HR/ATimeline
Jain Global LLC25,037$37.1K<0.01%-116,46013F-HRTimeline
FNY Investment Advisers, LLC25,400$37K0.01%new13F-HRTimeline
Connor, Clark & Lunn Investment Managem…24,340$36K<0.01%new13F-HRTimeline
Engineers Gate Manager LP23,488$34.8K<0.01%-7,93513F-HRTimeline
Blackstone Inc.in group Blackstone Inc.22,206$32.9K<0.01%013F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
Point72 Asia (Singapore) Pte. Ltd.21,905$32.4K0.01%-26,10213F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…20,749$30.7K<0.01%-2,56113F-HRTimelineGroup
Prosight Management, LP20,487$30.3K0.01%-816,91313F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …18,065$26.7K<0.01%013F-HRTimelineGroup
SG Americas Securities, LLC16,783$25K<0.01%-12,58213F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA16,175$24K<0.01%-28,45713F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp15,933$23.6K<0.01%-10213F-HRTimelineGroup
SIMPLEX TRADING, LLC12,989$19K<0.01%-29713F-HRTimeline
AlphaQuest LLC11,716$17.3K<0.01%013F-HRTimeline
Fiduciary Trust Coin group Fiduciary Trust Co11,620$17.2K<0.01%013F-HRTimelineGroup
China Universal Asset Management Co., L…10,760$15.9K<0.01%-1,56913F-HRTimeline
FMR LLCin group FMR LLC4,974$7.36K<0.01%-1,53313F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC4,319$6.39K<0.01%-19,60513F-HRTimelineGroup
GROUP ONE TRADING LLC3,121$4.62K<0.01%-1,50013F-HRTimeline
RHUMBLINE ADVISERS2,379$3.52K<0.01%013F-HRTimeline
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…2,373$3.51K<0.01%+213F-HRTimelineGroup
Caitong International Asset Management …2,047$3.03K<0.01%-3,50113F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…1,406$2.08K<0.01%-86713F-HRTimelineGroup
Fortitude Family Office, LLC1,278$1.89K<0.01%new13F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,264$1.87K<0.01%-24513F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…1,085$1.61K<0.01%new13F-HRTimelineGroup
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…984$1.46K<0.01%-73513F-HRTimelineGroup
Rise Advisors, LLC740$1.09K<0.01%013F-HRTimeline
CWM, LLCin group CWM, LLC657$1K<0.01%-2,64313F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…606$897<0.01%-26513F-HRTimeline
MAI Capital Management400$592<0.01%013F-HRTimeline
SBI Securities Co., Ltd.320$474<0.01%013F-HRTimeline
Bell Investment Advisors, Inc307$455<0.01%new13F-HRTimeline
Point72 (DIFC) Ltd112$166<0.01%-6,99613F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN50$74<0.01%-2,27913F-HRTimelineGroup
Truvestments Capital LLC50$74<0.01%-11713F-HRTimeline
COMERICA BANK14$21<0.01%013F-HRTimeline
Farther Finance Advisors, LLC5$7<0.01%013F-HRTimeline
Global Retirement Partners, LLC4$6<0.01%013F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.196$00%013F-HRTimelineGroupValue filed as zero, left out of ratios.
Covestor Ltd46$00%013F-HRTimelineValue filed as zero, left out of ratios.