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Venrock Adviser, LLC

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13F filer, CIK 1615982, NEW YORK, NY

Venrock Adviser, LLC reported $1,175,247,364 across 37 holdings for the quarter ended 2025-03-31, in a 13F-HR filed 2025-05-15. Its ten largest share positions make up 76.08% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001415889-25-013093

Period
2025-03-31
Reported value
$1.18B
Holdings
37
Top 10 weight
76.08%
New
4
Sold out
4

Largest buys vs the previous quarter

SecurityShares changeApprox. value
MTSRnew+3,750,662$102M
SLDBnew+2,481,400$9.18M
SVRAnew+3,257,639$9.02M
ORKAadded+862,808$8.85M
SRZNnew+632,931$7.38M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
MERUS N Vexited-592,411-$24.9M
AQSTexited-2,629,786-$9.36M
FDMTreduced-2,274,771-$7.35M
ORICreduced-1,212,000-$6.76M
TERNexited-1,077,090-$5.97M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q1 2025

Share positions as resolved from 13F-HR 0001415889-25-013093, largest first. % of portfolio is the value over $1,175,247,364, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
APGEAPOGEE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 8,493,321 shares; 2024Q4: 8,493,321 shares; 2025Q1: 8,493,321 shares 8,493,321$317M27%0Timeline
MTSRMETSERA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 3,750,662 shares 3,750,662$102M8.69%newTimeline
OCULOCULAR THERAPEUTIX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 12,762,462 shares; 2024Q4: 12,762,462 shares; 2025Q1: 12,762,462 shares 12,762,462$93.5M7.96%0Timeline
ELVNENLIVEN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 4,026,331 shares; 2024Q4: 4,026,331 shares; 2025Q1: 4,026,331 shares 4,026,331$79.2M6.74%0Timeline
KALVKALVISTA PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 6,249,731 shares; 2024Q4: 6,249,731 shares; 2025Q1: 6,703,985 shares 6,703,985$77.4M6.58%+454,254Timeline
VRDNVIRIDIAN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,882,709 shares; 2024Q4: 3,882,709 shares; 2025Q1: 3,882,709 shares 3,882,709$52.3M4.45%0Timeline
PHVSPHARVARIS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,395,606 shares; 2024Q4: 3,220,130 shares; 2025Q1: 3,112,720 shares 3,112,720$48.9M4.16%-107,410Timeline
SYRESPYRE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,685,448 shares; 2024Q4: 2,685,448 shares; 2025Q1: 2,685,448 shares 2,685,448$43.3M3.69%0Timeline
ORKAORUKA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,085,620 shares; 2024Q4: 3,285,620 shares; 2025Q1: 4,148,428 shares 4,148,428$42.6M3.62%+862,808Timeline
PRAXPRAXIS PRECISION MEDICINES IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 706,131 shares; 2024Q4: 989,985 shares; 2025Q1: 989,985 shares 989,985$37.5M3.19%0Timeline
COGTCOGENT BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 5,684,167 shares; 2024Q4: 5,684,411 shares; 2025Q1: 5,684,411 shares 5,684,411$34M2.9%0Timeline
DNTHDIANTHUS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,744,373 shares; 2024Q4: 1,744,373 shares; 2025Q1: 1,744,373 shares 1,744,373$31.6M2.69%0Timeline
DYNDYNE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,173,913 shares; 2024Q4: 2,173,913 shares; 2025Q1: 2,173,913 shares 2,173,913$22.7M1.93%0Timeline
CDTXCIDARA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 765,723 shares; 2025Q1: 1,051,518 shares 1,051,518$22.6M1.93%+285,795Timeline
ENGNENGENE HOLDINGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,565,841 shares; 2024Q4: 5,046,414 shares; 2025Q1: 5,046,414 shares 5,046,414$22.6M1.92%0Timeline
ERASERASCA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 16,216,216 shares; 2024Q4: 16,216,216 shares; 2025Q1: 16,216,216 shares 16,216,216$22.2M1.89%0Timeline
ORICORIC PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 4,394,527 shares; 2024Q4: 4,394,527 shares; 2025Q1: 3,182,527 shares 3,182,527$17.8M1.51%-1,212,000Timeline
UPBUPSTREAM BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 2,295,319 shares; 2025Q1: 2,295,319 shares 2,295,319$14M1.2%0Timeline
ASTRIA THERAPEUTICS INCASTRIA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,458,645 shares; 2024Q4: 2,457,348 shares; 2025Q1: 2,457,348 shares 2,457,348$13.1M1.12%0
CGEMCULLINAN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,379,965 shares; 2024Q4: 1,379,965 shares; 2025Q1: 1,379,965 shares 1,379,965$10.4M0.89%0Timeline
SLDBSOLID BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 2,481,400 shares 2,481,400$9.18M0.78%newTimeline
SVRASAVARA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 3,257,639 shares 3,257,639$9.02M0.77%newTimeline
ABVXABIVAX SAQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,345,780 shares; 2024Q4: 1,345,780 shares; 2025Q1: 1,345,780 shares 1,345,780$8.41M0.72%0Timeline
FRNMPERCEPTIVE CAP SOLUTIONS CORQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 750,000 shares; 2024Q4: 750,000 shares; 2025Q1: 750,000 shares 750,000$7.72M0.66%0Timeline
SRZNSURROZEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 632,931 shares 632,931$7.38M0.63%newTimeline
ZURAZURA BIO LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,023,166 shares; 2024Q4: 2,023,166 shares; 2025Q1: 5,023,166 shares 5,023,166$6.48M0.55%+3,000,000Timeline
ARTVARTIVA BIOTHERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,609,569 shares; 2024Q4: 1,609,569 shares; 2025Q1: 1,609,569 shares 1,609,569$4.83M0.41%0Timeline
TRVITREVI THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,422,656 shares; 2024Q4: 1,266,457 shares; 2025Q1: 615,506 shares 615,506$3.87M0.33%-650,951Timeline
Applied Therapeutics IncApplied Therapeutics IncQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 9,825,000 shares; 2024Q4: 9,990,591 shares; 2025Q1: 5,567,709 shares 5,567,709$2.72M0.23%-4,422,882
FDMT4D MOLECULAR THERAPEUTICS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 4,400,000 shares; 2024Q4: 2,952,371 shares; 2025Q1: 677,600 shares 677,600$2.19M0.19%-2,274,771Timeline
CASIFCASI PHARMACEUTICALS HLDGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 987,259 shares; 2024Q4: 987,259 shares; 2025Q1: 987,259 shares 987,259$2.13M0.18%0Timeline
TENXTENAX THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 208,333 shares; 2024Q4: 208,333 shares; 2025Q1: 208,333 shares 208,333$1.36M0.12%0Timeline
Mersana Therapeutics IncMersana Therapeutics IncQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 11,328,000 shares; 2024Q4: 10,257,790 shares; 2025Q1: 3,574,325 shares 3,574,325$1.23M0.1%-6,683,465
IPSCCENTURY THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 5,389,259 shares; 2024Q4: 3,957,186 shares; 2025Q1: 2,498,069 shares 2,498,069$1.19M0.1%-1,459,117Timeline
TNYATENAYA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,555,556 shares; 2024Q4: 1,555,556 shares; 2025Q1: 1,555,556 shares 1,555,556$887K0.08%0Timeline
GLYCOMIMETICS INCGLYCOMIMETICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 3,000,000 shares; 2025Q1: 3,000,000 shares 3,000,000$630K0.05%0
TILINSTIL BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 33,177 shares; 2024Q4: 33,177 shares; 2025Q1: 33,177 shares 33,177$576K0.05%0Timeline

Sold out in Q1 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
MERUS N VMERUS N V592,411$24.9Mshares
AQSTAQUESTIVE THERAPEUTICS INC2,629,786$9.36Mshares
TERNTERNS PHARMACEUTICALS INC1,077,090$5.97Mshares
TSHATAYSHA GENE THERAPIES INC3,225,180$5.58Mshares

How Q1 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001415889-25-013093 base2025-05-15acceptance time not in the bulk data set