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Sofinnova Investments, Inc.

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13F filer, CIK 1631134, Menlo Park, CA

Sofinnova Investments, Inc. reported $1,635,018,721 across 63 holdings for the quarter ended 2025-06-30, in a 13F-HR filed 2025-08-14. Its ten largest share positions make up 55.99% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001104659-25-078481

Period
2025-06-30
Reported value
$1.64B
Holdings
63
Top 10 weight
55.99%
New
18
Sold out
19

Largest buys vs the previous quarter

SecurityShares changeApprox. value
GILDadded+631,408$70M
ABBVnew+265,850$49.3M
BSXnew+431,200$46.3M
LLYadded+44,218$34.5M
UTHRnew+118,513$34.1M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
SYKexited-298,567-$111M
MDTexited-562,992-$50.6M
ALNYexited-176,181-$47.6M
BLUEPRINT MEDICINES CORPexited-261,039-$23.1M
BMYexited-371,497-$22.7M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q2 2025

Share positions as resolved from 13F-HR 0001104659-25-078481, largest first. % of portfolio is the value over $1,469,701,421, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
NTRANATERA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,550,280 shares; 2024Q4: 1,550,280 shares; 2025Q1: 1,550,280 shares; 2025Q2: 1,550,280 shares 1,550,280$262M17.82%0Timeline
GILDGILEAD SCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 774,227 shares; 2025Q1: 418,900 shares; 2025Q2: 1,050,308 shares 1,050,308$116M7.92%+631,408Timeline
LLYELI LILLY & COQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 14,364 shares; 2025Q1: 52,800 shares; 2025Q2: 97,018 shares 97,018$75.6M5.15%+44,218Timeline
JAZZJAZZ PHARMACEUTICALS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 188,562 shares; 2024Q4: 504,193 shares; 2025Q1: 510,050 shares; 2025Q2: 694,096 shares 694,096$73.7M5.01%+184,046Timeline
VERAVERA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,793,987 shares; 2024Q4: 2,793,987 shares; 2025Q1: 2,793,987 shares; 2025Q2: 2,793,987 shares 2,793,987$65.8M4.48%0Timeline
ABBVABBVIE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 359,393 shares; 2025Q1: not reported; 2025Q2: 265,850 shares 265,850$49.3M3.36%newTimeline
BSXBOSTON SCIENTIFIC CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 135,819 shares; 2024Q4: 346,571 shares; 2025Q1: not reported; 2025Q2: 431,200 shares 431,200$46.3M3.15%newTimeline
DXCMDEXCOM INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 290,210 shares; 2025Q1: 395,975 shares; 2025Q2: 523,694 shares 523,694$45.7M3.11%+127,719Timeline
IDYAIDEAYA BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,749,455 shares; 2024Q4: 1,069,090 shares; 2025Q1: 2,622,192 shares; 2025Q2: 2,147,795 shares 2,147,795$45.1M3.07%-474,397Timeline
BBIOBRIDGEBIO PHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 734,227 shares; 2025Q2: 993,093 shares 993,093$42.9M2.92%+258,866Timeline
ISRGINTUITIVE SURGICAL INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 37,896 shares; 2025Q1: 11,984 shares; 2025Q2: 70,642 shares 70,642$38.4M2.61%+58,658Timeline
RYTMRHYTHM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 276,678 shares; 2024Q4: 397,428 shares; 2025Q1: 446,839 shares; 2025Q2: 586,010 shares 586,010$37M2.52%+139,171Timeline
AVBPARRIVENT BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,696,752 shares; 2024Q4: 1,696,752 shares; 2025Q1: 1,696,752 shares; 2025Q2: 1,696,752 shares 1,696,752$36.9M2.51%0Timeline
ROIVROIVANT SCIENCES LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 1,279,510 shares; 2025Q2: 3,088,814 shares 3,088,814$34.8M2.37%+1,809,304Timeline
SLNOSOLENO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 586,344 shares; 2024Q4: 757,248 shares; 2025Q1: 484,471 shares; 2025Q2: 415,219 shares 415,219$34.8M2.37%-69,252Timeline
UTHRUNITED THERAPEUTICS CORP DELQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 118,513 shares 118,513$34.1M2.32%newTimeline
INSMINSMED INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 286,307 shares; 2024Q4: 256,281 shares; 2025Q1: 304,254 shares; 2025Q2: 313,923 shares 313,923$31.6M2.15%+9,669Timeline
AKROAKERO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 510,020 shares; 2025Q2: 548,788 shares 548,788$29.3M1.99%+38,768Timeline
SUPNSUPERNUS PHARMACEUTICALSQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 520,678 shares; 2025Q2: 799,253 shares 799,253$25.2M1.71%+278,575Timeline
ANABANAPTYSBIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 132,927 shares; 2025Q1: 1,160,033 shares; 2025Q2: 1,032,362 shares 1,032,362$22.9M1.56%-127,671Timeline
RAPPRAPPORT THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,995,594 shares; 2024Q4: 1,995,594 shares; 2025Q1: 1,995,594 shares; 2025Q2: 1,995,594 shares 1,995,594$22.7M1.54%0Timeline
QUREUNIQURE NVQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 545,771 shares; 2025Q2: 1,558,356 shares 1,558,356$21.7M1.48%+1,012,585Timeline
MERUS N VMERUS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 404,562 shares 404,562$21.3M1.45%new
AZNASTRAZENECA PLC-SPONS ADRQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 809,406 shares; 2024Q4: 651,344 shares; 2025Q1: not reported; 2025Q2: 293,661 shares 293,661$20.5M1.4%newTimeline
PTCTPTC THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 579,339 shares; 2025Q2: 375,939 shares 375,939$18.4M1.25%-203,400Timeline
INOZYME PHARMA INCINOZYME PHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 4,280,308 shares; 2024Q4: 4,280,308 shares; 2025Q1: 4,280,308 shares; 2025Q2: 4,280,308 shares 4,280,308$17.1M1.16%0
COGTCOGENT BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,265,230 shares; 2024Q4: 823,160 shares; 2025Q1: 2,182,121 shares; 2025Q2: 2,355,505 shares 2,355,505$16.9M1.15%+173,384Timeline
REPLREPLIMUNE GROUP INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 48,138 shares; 2024Q4: 3,149,522 shares; 2025Q1: 2,479,939 shares; 2025Q2: 1,806,529 shares 1,806,529$16.8M1.14%-673,410Timeline
RNAMAVIDITY BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 30,472 shares; 2024Q4: 13,789 shares; 2025Q1: 379,931 shares; 2025Q2: 584,801 shares 584,801$16.6M1.13%+204,870Timeline
SNDXSYNDAX PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 786,999 shares; 2024Q4: 658,627 shares; 2025Q1: 2,275,223 shares; 2025Q2: 1,524,440 shares 1,524,440$14.3M0.97%-750,783Timeline
CDTXCIDARA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 251,031 shares 251,031$12.2M0.83%newTimeline
IMTXIMMATICS N.VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 386,100 shares; 2024Q4: 343,206 shares; 2025Q1: 1,554,304 shares; 2025Q2: 2,240,528 shares 2,240,528$12.1M0.82%+686,224Timeline
EXASEXACT SCIENCES CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 37,637 shares; 2024Q4: 52,042 shares; 2025Q1: not reported; 2025Q2: 208,300 shares 208,300$11.1M0.75%newTimeline
PHVSPHARVARIS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 600,302 shares; 2024Q4: 560,723 shares; 2025Q1: 593,403 shares; 2025Q2: 585,532 shares 585,532$10.3M0.7%-7,871Timeline
INBXINHIBRX BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 536,068 shares; 2024Q4: 527,190 shares; 2025Q1: 697,916 shares; 2025Q2: 708,678 shares 708,678$10.1M0.69%+10,762Timeline
RCUSARCUS BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 1,037,776 shares; 2025Q2: 1,216,016 shares 1,216,016$9.9M0.67%+178,240Timeline
Y-mAbs Therapeutics IncY-mAbs Therapeutics IncQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,194,278 shares; 2024Q4: 2,194,278 shares; 2025Q1: 2,194,278 shares; 2025Q2: 2,194,278 shares 2,194,278$9.9M0.67%0
AXSMAXSOME THERAPEUTICS INC.Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 379,527 shares; 2024Q4: 491,726 shares; 2025Q1: 175,317 shares; 2025Q2: 93,610 shares 93,610$9.77M0.66%-81,707Timeline
BIOABIOAGE LABS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,304,901 shares; 2024Q4: 2,304,901 shares; 2025Q1: 2,304,901 shares; 2025Q2: 2,304,901 shares 2,304,901$9.52M0.65%0Timeline
EWTXEDGEWISE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 384,767 shares; 2024Q4: 402,773 shares; 2025Q1: 342,218 shares; 2025Q2: 716,873 shares 716,873$9.4M0.64%+374,655Timeline
IMNMIMMUNOME INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 676,766 shares; 2024Q4: 746,824 shares; 2025Q1: 788,666 shares; 2025Q2: 778,476 shares 778,476$7.24M0.49%-10,190Timeline
DYNDYNE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 772,070 shares; 2024Q4: 1,071,498 shares; 2025Q1: 716,896 shares; 2025Q2: 614,865 shares 614,865$5.85M0.4%-102,031Timeline
SVRASAVARA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 5,662,550 shares; 2024Q4: 5,471,299 shares; 2025Q1: 5,481,666 shares; 2025Q2: 2,457,352 shares 2,457,352$5.6M0.38%-3,024,314Timeline
APGEAPOGEE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 76,180 shares 76,180$3.31M0.23%newTimeline
NEXTCURE INCNEXTCURE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,671,856 shares; 2024Q4: 2,671,856 shares; 2025Q1: 2,671,856 shares; 2025Q2: 2,671,856 shares 2,671,856$1.23M0.08%0
ESTAESTABLISHMENT LABS HLDGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 181,476 shares; 2024Q4: 95,305 shares; 2025Q1: 28,675 shares; 2025Q2: 28,120 shares 28,120$1.2M0.08%-555Timeline
JBIOJADE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 107,391 shares 107,391$1.07M0.07%newTimeline
MTSRMETSERA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 36,800 shares; 2025Q2: 36,191 shares 36,191$1.03M0.07%-609Timeline
SRRKSCHOLAR ROCK HLDG CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 116,117 shares; 2025Q2: 26,440 shares 26,440$937K0.06%-89,677Timeline
BOLTBOLT BIOTHERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 137,721 shares 137,721$795K0.05%newTimeline
WVEWAVE LIFE SCIENCES LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 117,903 shares 117,903$766K0.05%newTimeline
GPCRSTRUCTURE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 38,792 shares; 2024Q4: 20,892 shares; 2025Q1: 34,952 shares; 2025Q2: 34,353 shares 34,353$712K0.05%-599Timeline
PRAXPRAXIS PRECISION MEDICINES IQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 157,640 shares; 2025Q2: 15,717 shares 15,717$661K0.04%-141,923Timeline
IKENA ONCOLOGY INCIKENA ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 382,616 shares; 2024Q4: 382,616 shares; 2025Q1: 382,616 shares; 2025Q2: 382,616 shares 382,616$513K0.03%0
IRONDISC MEDICINE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 41,352 shares; 2024Q4: 22,752 shares; 2025Q1: 7,485 shares; 2025Q2: 7,312 shares 7,312$387K0.03%-173Timeline

Options

Puts and calls, as filed. The amount and value describe the underlying shares, not the option premium, so they stay out of % of portfolio (H5).

SecurityTypeAmountValueChange
IWMISHARES TR SHSput250,000$53.9M-100,000
IBBISHARES TR ISHARES BIOTECHput375,000$47.4Mnew
SMMTSUMMIT THERAPEUTICS INC COMcall700,000$14.9Mnew
RYTMRHYTHM PHARMACEUTICALS INC COMput225,000$14.2Mnew
REPLREPLIMUNE GROUP INC COMMON STOCKput1,500,000$13.9Mnew
ROIVROIVANT SCIENCES LTD SHScall1,000,000$11.3Mnew
CDTXCIDARA THERAPEUTICS INC COM NEWcall100,000$4.87Mnew
COGTCOGENT BIOSCIENCES INC COMcall660,000$4.74Mnew

Sold out in Q2 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
SYKSTRYKER CORPORATION298,567$111Mshares
QQQINVESCO QQQ TR175,000$82.1Mput
MDTMEDTRONIC PLC562,992$50.6Mshares
ALNYALNYLAM PHARMACEUTICALS INC176,181$47.6Mshares
SLNOSOLENO THERAPEUTICS INC529,300$37.8Mput
BLUEPRINT MEDICINES CORPBLUEPRINT MEDICINES CORP261,039$23.1Mshares
BMYBRISTOL-MYERS SQUIBB CO371,497$22.7Mshares
INCYINCYTE CORP357,800$21.7Mshares
SRPTSAREPTA THERAPEUTICS INC327,618$20.9Mshares
DHRDANAHER CORP DEL58,606$12Mshares
PENPENUMBRA INC42,936$11.5Mshares
AEROVATE THERAPEUTICS INCAEROVATE THERAPEUTICS INC3,758,686$9.43Mshares
ACADACADIA PHARMACEUTICALS INC500,000$8.3Mcall
EWTXEDGEWISE THERAPEUTICS INC320,400$7.05Mput
KURAKURA ONCOLOGY INC791,667$5.23Mshares
ERASERASCA INC1,877,085$2.57Mshares
BOLT BIOTHERAPEUTICS INCBOLT BIOTHERAPEUTICS INC2,754,437$1.1Mshares
ELVNENLIVEN THERAPEUTICS INC33,547$660Kshares
VIRVIR BIOTECHNOLOGY INC83,010$538Kshares

How Q2 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001104659-25-078481 base2025-08-14acceptance time not in the bulk data set