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Disclosery

VRTX VERTEX PHARMACEUTICALS INC

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COM (common), issuer CIK 875320

1,632 managers (1,675 13F filers) reported a position in VRTX shares at 2025-12-31, 241,593,776 shares in all. 163 filers opened a position and 101 filers sold out during the quarter.

Managers
1,632
13F filers
1,675
New
163
Added
620
Reduced
566
Sold out
101
Shares held by filers
241,593,776

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
GATEWAY INVESTMENT ADVISERS LLC66,108$30M0.28%+18213F-HRTimeline
XPONANCE LLC65,773$29.8M0.22%+3,28213F-HRTimeline
GF FUND MANAGEMENT CO. LTD.65,411$29.7M0.51%+2,62013F-HRTimeline
DAVIDSON INVESTMENT ADVISORS64,227$29.1M1.21%+1,80613F-HRTimeline
Hardman Johnston Global Advisors LLC63,806$28.9M1.38%-15,34613F-HRTimeline
MACKENZIE FINANCIAL CORP63,299$28.7M0.03%+8,95613F-HRTimeline
TRILLIUM ASSET MANAGEMENT, LLC62,693$28.6M0.87%-5,69213F-HRTimeline
Sumitomo Mitsui DS Asset Management Com…in group SUMITOMO MITSUI FINANCIAL GRO…62,761$28.5M0.22%+7,76713F-HRTimelineGroup
Allianz SEgroup of 2 filers holding61,457$27.9M-72,625Timeline
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCH…59,016$26.8M0.14%-2,55313F-HRTimeline
OFI INVEST ASSET MANAGEMENT69,124$26.7M0.38%+68,83213F-HRTimeline
FOSTER DYKEMA CABOT & PARTNERS, LLC58,344$26.5M1.63%-2,34513F-HRTimeline
ZACKS INVESTMENT MANAGEMENT56,626$25.7M0.2%-1,40013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC56,594$25.7M0.08%+81613F-HRTimeline
ATWOOD & PALMER INC55,392$25.1M1.43%+9513F-HRTimeline
AMALGAMATED BANK55,120$25M0.18%-1,39413F-HRTimeline
MOODY LYNN LIEBERSON & WALKER, LLC54,992$24.9M1.32%-1,56713F-HRTimeline
Edgemoor Investment Advisors, Inc.54,839$24.9M1.93%-35513F-HRTimeline
CIBC Bancorp USA Inc.group of 2 filers holding54,797$24.8M+47,999Timeline
COMMONWEALTH EQUITY SERVICES, LLC54,143$24.5M0.03%-4,14213F-HRTimeline
Retirement Systems of Alabama53,976$24.5M0.08%-71713F-HRTimeline
Reynders McVeigh Capital Management, LLC53,905$24.4M1.15%-1,44513F-HRTimeline
Harvest Fund Management Co., Ltdin group Harvest Fund Management Co., …54,198$24.4M0.92%+3,52713F-HRTimelineGroup
FORSTA AP-FONDEN53,480$24.2M0.14%-1,52013F-HRTimeline
Smith Group Asset Management, LLC52,051$23.6M1.25%+3,19413F-HRTimeline
CULLINAN ASSOCIATES INC51,312$23.3M1.58%-10013F-HRTimeline
Hemenway Trust Co LLC51,017$23.1M1.77%-4,10813F-HRTimeline
VALLEY WEALTH MANAGERS, INC.in group VALLEY WEALTH MANAGERS, INC.50,951$23.1M1.48%+1,13213F-HRTimelineGroup
CI INVESTMENTS INC.in group CI INVESTMENTS INC.49,891$22.6M0.1%+38,90013F-HRTimelineGroup
Sanctuary Advisors, LLC49,804$22.6M0.12%+3,55113F-HRTimeline
IFM Investors Pty Ltd49,780$22.6M0.19%+29613F-HRTimeline
PensionDanmark Pensionsforsikringsaktie…49,381$22.4M0.2%13F-HRTimeline
Lido Advisors, LLCin group Lido Advisors, LLC53,597$22.1M0.09%-9813F-HRTimelineGroup
Zurich Insurance Group Ltd/FIin group Zurich Insurance Group Ltd/FI48,699$22.1M0.15%new13F-HRTimelineGroup
China Universal Asset Management Co., L…48,047$21.8M1.67%+2,93313F-HRTimeline
Rakuten Group, Inc.group of 2 filers holding47,206$21.7M-195,275Timeline
HighTower Advisors, LLC47,559$21.6M0.02%+3,54413F-HRTimeline
O'SHAUGHNESSY ASSET MANAGEMENT, LLC47,245$21.4M0.12%+11,56413F-HRTimeline
CREDIT AGRICOLE S Ain group CREDIT AGRICOLE S A46,894$21.3M0.06%-15,49313F-HRTimelineGroup
Illinois Municipal Retirement Fund46,786$21.2M0.27%-6,01513F-HRTimeline
ODDO BHF ASSET MANAGEMENT SAS46,633$21.1M0.79%+13,35513F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
C WorldWide Group Holding A/Sin group C WorldWide Group Holding A/S46,057$20.9M0.36%013F-HRTimelineGroup
Trexquant Investment LP46,053$20.9M0.19%+40,63713F-HRTimeline
Pathstone Holdings, LLCin group Pathstone Holdings, LLC45,604$20.7M0.08%+7,72513F-HRTimelineGroup
BRITISH COLUMBIA INVESTMENT MANAGEMENT …45,496$20.6M0.11%-86,35113F-HRTimeline
USS Investment Management Ltd45,393$20.6M0.1%+1,29413F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
MACQUARIE GROUP LTDin group MACQUARIE GROUP LTD44,736$20.3M0.09%-178,82013F-HRTimelineGroup
CAPITAL GROUP INVESTMENT MANAGEMENT PTE…group of 2 filers holding44,717$20.3M-6,443Timeline
Calamos Advisors LLCgroup of 2 filers holding44,617$20.2M-1,136Timeline
W.G. Shaheen & Associates DBA Whitney &…44,164$20M1.59%+60813F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.43,752$19.8M0.03%-40,49813F-HRTimelineGroup
Gradient Investments LLCin group Gradient Investments LLC43,595$19.8M0.31%+2,61813F-HRTimelineGroup
CITIZENS FINANCIAL GROUP INC/RIin group CITIZENS FINANCIAL GROUP INC/…43,403$19.7M0.26%+52213F-HRTimelineGroup
MARTINGALE ASSET MANAGEMENT L P43,221$19.6M0.5%+6,69913F-HRTimeline
Wealthfront Advisers LLC43,169$19.6M0.04%+5,79613F-HRTimeline
Utah Retirement Systems42,490$19.3M0.18%-913F-HRTimeline
Varma Mutual Pension Insurance Co40,626$18.4M0.11%+5,70013F-HRTimeline
TEACHERS RETIREMENT SYSTEM OF THE STATE…40,323$18.3M0.14%-2,25813F-HRTimeline
Osmosis Investment Management UK Ltd40,294$18.3M0.46%13F-HRTimeline
SEGALL BRYANT & HAMILL, LLC39,819$18.1M0.24%-1,15213F-HRTimeline
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC39,735$18M0.05%+39,13913F-HRTimeline
Police & Firemen's Retirement System of…39,473$17.9M0.15%-1,90313F-HRTimeline
Tweedy, Browne Co LLC39,148$17.7M1.43%+8313F-HRTimeline
Ilmarinen Mutual Pension Insurance Co38,800$17.6M0.14%013F-HRTimeline
Aristotle Atlantic Partners, LLCin group ARISTOTLE INVESTMENT SERVICES…38,391$17.4M0.8%-1,41313F-HRTimelineGroup
MML INVESTORS SERVICES, LLC38,004$17.2M0.04%+3,77313F-HRTimeline
iA Global Asset Management Inc.37,685$17.1M0.22%+1,84313F-HRTimeline
SHELTON CAPITAL MANAGEMENT37,241$16.9M0.33%+56213F-HRTimeline
VIRGINIA RETIREMENT SYSTEMS ET Al37,100$16.8M0.1%013F-HRTimeline
New York Life Investment Management LLCin group New York Life Investment Mana…36,818$16.7M0.14%-61413F-HRTimelineGroup
FLPUTNAM INVESTMENT MANAGEMENT CO36,791$16.7M0.24%+2,11513F-HRTimeline
Vestcor Inc36,690$16.6M0.47%+1,42413F-HRTimeline
Andra AP-fonden35,940$16.3M0.2%+4013F-HRTimeline
MCRAE CAPITAL MANAGEMENT INC35,558$16.1M3.29%+2,39913F-HRTimeline
SAPIENT CAPITAL LLC34,324$15.6M0.22%+1313F-HRTimeline
Galvin, Gaustad & Stein, LLC34,309$15.6M1.21%+1,16713F-HRTimeline
Rhenman & Partners Asset Management AB34,255$15.5M1.45%-12,70013F-HRTimeline
BAILARD, INC.33,975$15.4M0.34%-66413F-HRTimeline
AIA Group Ltdin group AIA Group Ltd33,821$15.3M0.23%-22,23313F-HRTimelineGroup
HUNTINGTON NATIONAL BANKin group HUNTINGTON NATIONAL BANK32,999$15M0.09%+3,55213F-HRTimelineGroup
State of Alaska, Department of Revenue32,915$14.9M0.16%-2,93813F-HRTimeline
Public Sector Pension Investment Board32,851$14.9M0.05%+10,43313F-HRTimeline
Foster Victor Wealth Advisors, LLC32,929$14.5M0.85%-92813F-HRTimeline
Elo Mutual Pension Insurance Co31,613$14.3M0.22%-2,17013F-HRTimeline
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.31,372$14.2M0.12%+15,37213F-HRTimelineGroup
FIDEURAM - INTESA SANPAOLO PRIVATE BANK…31,281$14.2M0.51%13F-HR/ATimeline
BARLOW WEALTH PARTNERS, LLC30,087$14M1.51%+20713F-HRTimeline
Louisiana State Employees Retirement Sy…30,000$13.6M0.23%-2,20013F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\29,850$13.5M0.02%-1,00613F-HRTimelineGroup
Washington Trust Bank29,839$13.5M0.95%+3013F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
Apollon Wealth Management, LLCin group Apollon Wealth Management, LLC29,195$13.2M0.23%-17113F-HRTimelineGroup
OREGON PUBLIC EMPLOYEES RETIREMENT FUND29,044$13.2M0.17%-24113F-HRTimeline
Caprock Group, LLC29,023$13.2M0.28%+3,80713F-HRTimeline
PROFUND ADVISORS LLC28,818$13.1M0.4%+2,42313F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC28,530$12.9M0.12%-5,83113F-HRTimeline
OP Asset Management Ltd28,452$12.9M0.16%+16413F-HR/ATimeline
Walleye Capital LLCgroup of 2 filers holding28,313$12.8M+25,851Timeline
Atria Investments, Inc28,261$12.8M0.15%+2,34213F-HRTimeline
MassMutual Private Wealth & Trust, FSB27,914$12.7M0.33%-58113F-HRTimeline
Shelter Mutual Insurance Coin group Shelter Mutual Insurance Co27,600$12.5M2.79%013F-HRTimelineGroup
Avanza Fonder AB27,585$12.5M0.32%+53213F-HRTimeline
Bridgewater Associates, LP27,488$12.5M0.05%-10,83613F-HRTimeline
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCin group MUTUAL OF AMERICA CAPITAL MAN…27,197$12.3M0.13%-54913F-HRTimelineGroup
Bogart Wealth, LLC27,177$12.3M0.49%+1,02813F-HRTimeline
Americana Partners, LLC27,133$12.3M0.34%+2,66513F-HRTimeline
FAGAN ASSOCIATES, INC.26,566$12M1.61%+26013F-HRTimeline
BENDER ROBERT & ASSOCIATES26,463$12M2.49%+13313F-HRTimeline
Generate Investment Management Ltd26,334$11.9M0.54%+60013F-HRTimeline
CCM INVESTMENT ADVISERS LLC26,249$11.9M1.14%-2,06013F-HRTimeline
ARK Investment Management LLCin group ARK Investment Management LLC26,100$11.8M0.08%+43513F-HRTimelineGroup
ASR Vermogensbeheer N.V.26,059$11.8M0.14%-23513F-HRTimeline
LVM CAPITAL MANAGEMENT LTD/MI25,775$11.7M1.09%-6513F-HRTimeline
Kestra Advisory Services, LLCgroup of 3 filers holding25,527$11.6M+137Timeline
MERITAGE PORTFOLIO MANAGEMENT25,438$11.5M0.77%-50213F-HRTimeline
PINNACLE ASSOCIATES LTD25,238$11.4M0.15%-12913F-HRTimeline
Fisher Asset Management, LLC25,218$11.4M<0.01%-74113F-HRTimeline
Biondo Investment Advisors, LLC25,140$11.4M1.38%+6513F-HRTimeline
Jain Global LLC24,978$11.3M0.11%new13F-HRTimeline
Advisors Asset Management, Inc.24,713$11.2M0.19%-1,21313F-HR/ATimeline
BANQUE PICTET & CIE SA24,328$11M0.11%+15,47013F-HRTimeline
Norinchukin Bank, Thein group Norinchukin Bank, The24,203$11M0.13%+2,17713F-HRTimelineGroup
Eurizon SLJ Capital Ltd24,156$11M4.34%13F-HRTimeline
FIFTH THIRD BANK, NATIONAL ASSOCIATIONgroup of 2 filers holding23,872$10.8M-151Timeline
YOUSIF CAPITAL MANAGEMENT, LLC24,304$10.7M0.12%-1,35813F-HRTimeline
SOMERVILLE KURT F23,327$10.6M1.79%+68413F-HRTimeline
Atle Fund Management AB22,984$10.4M3.32%+5,21813F-HRTimeline
CARY STREET PARTNERS ASSET MANAGEMENT L…group of 2 filers holding22,950$10.4M-365Timeline
Kentucky Retirement Systemsgroup of 2 filers holding22,915$10.4M0Timeline
Waverly Advisors, LLC22,732$10.3M0.08%+2,48413F-HRTimeline
IEQ CAPITAL, LLC22,524$10.2M0.03%+16,07313F-HRTimeline
KENNEDY CAPITAL MANAGEMENT LLC22,414$10.2M0.22%+23413F-HRTimeline
EXENCIAL WEALTH ADVISORS, LLC22,382$10.1M0.32%+20,88213F-HRTimeline
Telos Capital Management, Inc.22,376$10.1M0.95%+1,18813F-HRTimeline
Investment Management Corp of Ontario22,300$10.1M0.13%+7,06513F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC22,210$10.1M0.02%+21,95313F-HRTimelineGroup
&PARTNERS22,138$10M0.05%-5,81113F-HRTimeline
EULAV Asset Management22,000$9.97M0.27%013F-HRTimeline
Gotham Asset Management, LLC21,511$9.75M0.04%-37713F-HRTimeline
Modera Wealth Management, LLC21,275$9.65M0.11%-57813F-HRTimeline
GRANDFIELD & DODD, LLC21,231$9.63M0.55%+1,41113F-HRTimeline
OPPENHEIMER ASSET MANAGEMENT INC.group of 2 filers holding20,992$9.52M-8,072Timeline
CAMDEN NATIONAL BANK20,968$9.51M1.31%+7613F-HRTimeline
SIG BROKERAGE, LP20,864$9.46M3.18%-5,52613F-HRTimeline
AIMZ Investment Advisors, LLC20,261$9.19M2.63%-10013F-HRTimeline
Heirloom Wealth Management20,199$9.16M2.12%+23313F-HRTimeline
Fiduciary Trust Coin group Fiduciary Trust Co20,032$9.08M0.1%-1,88913F-HRTimelineGroup
UniSuper Management Pty Ltd19,992$9.06M0.05%-50313F-HRTimeline
MERCER GLOBAL ADVISORS INC /ADV23,822$8.99M0.01%+5,03813F-HRTimeline
ALLSTATE CORPin group ALLSTATE CORP19,095$8.66M0.12%+9,80313F-HRTimelineGroup
GW HENSSLER & ASSOCIATES LTD18,834$8.54M0.41%-3,95713F-HRTimeline
Azimuth Capital Investment Management L…18,742$8.5M0.3%-1,60613F-HRTimeline
Diversify Advisory Services, LLCgroup of 2 filers holding18,817$8.46M-707Timeline
Pinnacle Financial Partners, Inc.in group Pinnacle Financial Partners, …18,588$8.43M0.06%13F-HR/ATimelineGroup
Generali Asset Management SPA SGR18,538$8.4M0.17%-5,03113F-HRTimeline
QRG CAPITAL MANAGEMENT, INC.18,396$8.34M0.09%+2,56313F-HRTimeline
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.in group LANDSCAPE CAPITAL MANAGEMENT,…18,054$8.18M0.55%+7,57013F-HRTimelineGroup
MIZUHO SECURITIES USA LLCin group MIZUHO FINANCIAL GROUP INC18,474$8.01M0.13%-20013F-HRTimelineGroup
NIA IMPACT ADVISORS, LLC17,638$8M2.68%+1,70513F-HRTimeline
OSSIAM17,594$7.98M0.16%+4,65413F-HRTimeline
Sterling Capital Management LLC17,542$7.95M0.13%+6413F-HRTimeline
Simplify Asset Management Inc.17,492$7.93M0.13%+16,26713F-HRTimeline
JACOBS LEVY EQUITY MANAGEMENT, INC17,416$7.9M0.03%-7,53313F-HRTimeline
Steward Partners Investment Advisory, L…17,364$7.87M0.04%-9,99713F-HRTimeline
NewEdge Advisors, LLC17,335$7.86M0.03%+5,61713F-HRTimeline
Broderick Brian C17,202$7.8M1.47%-4913F-HRTimeline
Ameritas Investment Partners, Inc.group of 2 filers holding17,023$7.72M+2,013Timeline
Tidal Investments LLCin group Tidal Investments LLC16,838$7.63M0.03%+2,20613F-HRTimelineGroup
Fulcrum Capital LLC16,616$7.53M1.51%+36013F-HRTimeline
Trifecta Capital Advisors, LLC16,497$7.48M1.11%+66413F-HRTimeline
LMR Partners LLPin group LMR Partners LLP16,468$7.47M0.07%+36713F-HRTimelineGroup
Aptus Capital Advisors, LLC16,442$7.45M0.06%+68713F-HRTimeline
Madison Asset Management, LLCin group Madison Asset Management, LLC16,435$7.45M0.09%+23413F-HRTimelineGroup
NORTHWESTERN MUTUAL INVESTMENT MANAGEME…group of 2 filers holding16,407$7.44M-71Timeline
LEUTHOLD GROUP, LLC16,407$7.44M0.8%+3,56413F-HRTimeline
BLAIR WILLIAM & CO/IL16,090$7.29M0.02%-1,90013F-HRTimeline
Boston Common Asset Management, LLC16,081$7.29M0.44%-24,81813F-HR/ATimeline
SILVERCREST ASSET MANAGEMENT GROUP LLC16,028$7.27M0.05%-93113F-HRTimeline
Ethic Inc.15,983$7.25M0.11%+2,01213F-HRTimeline
PRUDENTIAL PLCin group PRUDENTIAL PLC15,771$7.15M0.06%-79713F-HRTimelineGroup
ANDERSON HOAGLAND & CO15,734$7.13M0.61%-3313F-HRTimeline
Third View Private Wealth, LLC15,717$7.13M0.96%13F-HRTimeline
PREVAIL INNOVATIVE WEALTH ADVISORS, LLC15,613$7.08M1.27%+41313F-HRTimeline
Bleakley Financial Group, LLC15,594$7.07M0.12%new13F-HRTimeline
Baldwin Investment Management, LLC15,554$7.05M0.8%-19413F-HRTimeline
Janney Capital Management LLC15,542$7.05M0.44%-16513F-HRTimeline
OMERS ADMINISTRATION Corp15,479$7.02M0.05%+1,72513F-HRTimeline
Torray Investment Partners LLC15,466$7.01M1%-78913F-HRTimeline
PUZO MICHAEL J15,371$6.97M1.9%-13013F-HRTimeline
NLB Skladi, upravljanje premozenja, d.o…15,151$6.87M0.31%13F-HRTimeline
Liontrust Investment Partners LLP15,046$6.82M0.1%-15,25413F-HRTimeline
Empowered Funds, LLC14,806$6.71M0.11%+1,22313F-HR/ATimeline
M&T Bank Corpin group M&T Bank Corp14,732$6.68M0.02%+2,40813F-HR/ATimelineGroup
HARTFORD INVESTMENT MANAGEMENT CO14,662$6.65M0.2%-36013F-HRTimeline
Daiichi Life Insurance Co., Ltd.in group Daiichi Life Insurance Co., L…14,538$6.59M0.17%+2,40013F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
PRINCETON CAPITAL MANAGEMENT LLC14,509$6.58M1.7%+7113F-HRTimeline
Callan Family Office, LLC14,440$6.55M0.14%+3,23513F-HRTimeline
Cambridge Investment Research Advisors,…14,357$6.51M0.02%+24013F-HRTimeline
Atlantic Union Bankshares Corpin group Atlantic Union Bankshares Corp14,233$6.45M0.12%-45513F-HRTimelineGroup
Meiji Yasuda Life Insurance Cogroup of 2 filers holding14,226$6.45M-312Timeline
Hamilton Capital Partners Inc.14,220$6.45M0.24%+1,89113F-HRTimeline