13F-HR filed by Casdin Capital, LLC
Casdin Capital, LLC filed this 13F-HR for the quarter ended 2025-12-31, filed 2026-02-17, with 38 holding rows worth $1,609,916,188.
- Accession
- 0000919574-26-001181
- Filer
- CIK 1534261
- Filed
- 2026-02-17
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2025
A holdings report, 38 entries on the cover page, a total value of $1,609,916,188 stated on the cover page (in dollars after the unit check, H1), rows summing to $1,609,916,188 with VALUE read as dollars as filed, 13F file number 028-17113. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| GENEDX HOLDINGS CORP | 81663L200 | COM CL A | 3,007,164 | $391,111,750 | dollars as filed | |
| REVOLUTION MEDICINES INC COM | 76155X100 | Stock | 2,577,333 | $205,284,573 | dollars as filed | |
| BIOLIFE SOLUTIONS INC COM NEW | 09062W204 | Stock | 5,957,165 | $144,044,250 | dollars as filed | |
| STANDARD BIOTOOLS INC | 34385P108 | COM | 88,783,856 | $113,643,336 | dollars as filed | |
| RELAY THERAPEUTICS INC COM | 75943R102 | Stock | 13,003,574 | $110,010,236 | dollars as filed | |
| STRUCTURE THERAPEUTICS INC COMP | 86366E106 | EQUITY | 1,175,000 | $81,721,250 | dollars as filed | |
| ILLUMINA INC | 452327109 | COM | 600,000 | $78,696,000 | dollars as filed | |
| AVIDITY BIOSCIENCES INC COM | 05370A108 | Stock | 1,000,000 | $72,130,000 | dollars as filed | |
| BEAM THERAPEUTICS INC | 07373V105 | COM | 1,600,000 | $44,352,000 | dollars as filed | |
| GUARDANT HEALTH INC COM | 40131M109 | Stock | 380,000 | $38,813,200 | dollars as filed | |
| MAZE THERAPEUTICS INC COM | 578784100 | Stock | 758,857 | $31,439,446 | dollars as filed | |
| DENALI THERAPEUTICS INC COM | 24823R105 | Stock | 1,840,000 | $30,378,400 | dollars as filed | |
| ALNYLAM PHARMACEUTICALS INC COM | 02043Q107 | Stock | 75,000 | $29,823,750 | dollars as filed | |
| NEUROGENE INC | 64135M105 | COMMON STOCK | 1,295,361 | $26,684,437 | dollars as filed | |
| 10X GENOMICS INC CL A COM | 88025U109 | Stock | 1,400,000 | $22,834,000 | dollars as filed | |
| ARS PHARMACEUTICALS INC | 82835W108 | COM | 1,600,000 | $18,640,000 | dollars as filed | |
| TEMPUS AI INC CL A | 88023B103 | Stock | 294,127 | $17,368,199 | dollars as filed | |
| UnitedHealth Group Inc | 91324P102 | COM | 50,000 | $16,505,500 | dollars as filed | |
| SEPTERNA INC COM | 81734D104 | Stock | 553,268 | $15,425,112 | dollars as filed | |
| HIMS & HERS HEALTH INC | 433000106 | COM CL A | 385,000 | $12,500,950 | dollars as filed | |
| VERACYTE INC COM | 92337F107 | Stock | 276,308 | $11,632,567 | dollars as filed | |
| DEXCOM INC COM | 252131107 | Stock | 175,000 | $11,614,750 | dollars as filed | |
| SCHOLAR ROCK HLDG CORP | 80706P103 | COM | 260,000 | $11,453,000 | dollars as filed | |
| Cigna Corporation | 125523100 | COM | 40,000 | $11,009,200 | dollars as filed | |
| PRIME MEDICINE INC | 74168J101 | COM | 3,167,175 | $10,990,097 | dollars as filed | |
| INCYTE CORP COM | 45337C102 | Stock | 100,000 | $9,877,000 | dollars as filed | |
| QUEST DIAGNOSTICS INC COM | 74834L100 | Stock | 50,000 | $8,676,500 | dollars as filed | |
| TAYSHA GENE THERAPIES INC | 877619106 | COMMON STOCK | 1,500,000 | $8,250,000 | dollars as filed | |
| PACIFIC BIOSCIENCES CALIF INC COM | 69404D108 | Stock | 4,223,767 | $7,898,444 | dollars as filed | |
| LEGEND BIOTECH CORP | 52490G102 | SPONSORED ADS | 215,000 | $4,674,100 | dollars as filed | |
| BRIDGEBIO ONCOLOGY THERAPEUT | 107924102 | COM NEW | 282,312 | $3,534,546 | dollars as filed | |
| ABSCI CORPORATION | 00091E109 | COM | 973,260 | $3,396,677 | dollars as filed | |
| CONTINEUM THERAPEUTICS INC CL A | 21217B100 | Stock | 148,333 | $1,695,446 | dollars as filed | |
| MONTE ROSA THERAPEUTICS INC | 61225M102 | COM | 86,014 | $1,348,700 | dollars as filed | |
| CENTURY THERAPEUTICS INC | 15673T100 | COM | 1,228,190 | $1,221,803 | dollars as filed | |
| RECURSION PHARMACEUTICALS IN | 75629V104 | CL A | 165,323 | $676,171 | dollars as filed | |
| GINKGO BIOWORKS HOLDINGS INC | 37611X209 | COMMON STOCK | 36,493 | $303,257 | dollars as filed | |
| TENAYA THERAPEUTICS INC | 87990A106 | COM | 361,969 | $257,541 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0000919574-26-001181 | this filing | 2026-02-17 | acceptance time not in the bulk data set |