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Disclosery

SNDX SYNDAX PHARMACEUTICALS INC

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COM (common), issuer CIK 1395937

227 managers (230 13F filers) reported a position in SNDX shares at 2025-12-31, 99,957,702 shares in all. 27 filers opened a position and 27 filers sold out during the quarter.

Managers
227
13F filers
230
New
27
Added
83
Reduced
80
Sold out
27
Shares held by filers
99,957,702

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
BlackRock, Inc.in group BlackRock, Inc.8,239,002$173M<0.01%-386,24213F-HRTimelineGroup
Kynam Capital Management, LP8,050,959$169M11.01%-469,04113F-HRTimeline
VANGUARD GROUP INCin group VANGUARD GROUP INC6,230,334$131M<0.01%+1,091,71713F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC5,695,375$120M0.02%+208,94113F-HR/ATimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.4,882,053$103M0.16%+627,00613F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/4,710,746$99M0.01%+1,012,99313F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP4,596,552$96.6M<0.01%+743,00313F-HRTimelineGroup
Eversept Partners, LP3,314,408$69.6M3.9%-152,90613F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources2,421,666$50.9M0.01%+31,10513F-HRTimelineGroup
KINGDON CAPITAL MANAGEMENT, L.L.C.2,350,000$49.4M7.56%-150,00013F-HRTimeline
Hood River Capital Management LLC2,316,553$48.7M0.53%new13F-HRTimeline
Soleus Capital Management, L.P.2,247,110$47.2M2%+235,00013F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC2,090,932$43.9M<0.01%-39913F-HRTimelineGroup
Elmind Capital, LP1,855,000$39M11.5%13F-HRTimeline
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding1,779,688$37.4M+683,977Timeline
Ensign Peak Advisors, Inc1,598,544$33.6M0.06%+789,48013F-HR/ATimeline
Nuveen, LLCin group TIAA1,483,002$31.2M0.01%+7,20413F-HRTimelineGroup
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …1,375,681$28.9M0.03%+139,60413F-HRTimelineGroup
STEMPOINT CAPITAL LP1,339,379$28.1M4.83%-26,82613F-HRTimeline
MPM BIOIMPACT LLC1,337,702$28.1M3.22%-37,97213F-HRTimeline
Aisling Capital Management LP1,316,806$27.7M5.78%013F-HRTimeline
Woodline Partners LP1,250,668$26.3M0.1%-299,85213F-HRTimeline
EVENTIDE ASSET MANAGEMENT, LLC1,238,196$26M0.41%+249,71013F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.1,219,609$25.6M0.02%+142,02413F-HRTimelineGroup
Catalio Capital Management, LP1,196,807$25.1M4.44%-417,91013F-HR/ATimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp1,094,151$23M<0.01%+41,81613F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY1,075,501$22.6M<0.01%-123,79513F-HR/ATimelineGroup
ALGERT GLOBAL LLC928,088$19.5M0.3%-2,67813F-HR/ATimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC925,974$19.5M0.01%+367,89813F-HRTimelineGroup
Candriam S.C.A.925,332$19.4M0.1%013F-HR/ATimeline
UBS Group AGgroup of 2 filers holding858,626$18M-950,148Timeline
Palo Alto Investors LP794,507$16.7M2.32%+139,57713F-HRTimeline
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.762,563$16M3.35%+374,84713F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC748,920$15.7M0.02%+10,65413F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP728,921$15.3M<0.01%-47,76513F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co727,424$15.3M<0.01%+8,39013F-HRTimelineGroup
Apis Capital Advisors, LLC724,000$15.2M2.65%+86,00013F-HRTimeline
Qube Research & Technologies Ltd688,137$14.5M0.02%-956,70713F-HRTimeline
Prosight Management, LP665,000$14M2.89%-338,40013F-HRTimeline
SILVERARC CAPITAL MANAGEMENT, LLCin group SILVERARC CAPITAL MANAGEMENT,…642,899$13.5M1.95%+179,19113F-HRTimelineGroup
Parkman Healthcare Partners LLC574,023$12.1M1.15%-272,87613F-HRTimeline
ExodusPoint Capital Management, LP554,761$11.7M0.13%+482,29713F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC544,800$11.4M0.02%-315,70013F-HRTimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…515,129$10.8M0.21%+390,55413F-HRTimelineGroup
Rhenman & Partners Asset Management AB487,000$10.2M0.96%-87,00013F-HRTimeline
Knott David M Jr415,000$8.72M4.04%-13,00013F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO378,504$7.95M<0.01%+124,65413F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc372,792$7.83M0.01%013F-HRTimelineGroup
Granahan Investment Management, LLC366,793$7.71M0.33%-29,54313F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC314,672$6.61M<0.01%-33,38913F-HRTimelineGroup
Pale Fire Capital SEin group Pale Fire Capital284,460$5.98M0.77%new13F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC282,587$5.94M<0.01%+187,14413F-HRTimelineGroup
DAFNA Capital Management LLC277,855$5.84M1.36%-222,84713F-HRTimeline
SECTOR GAMMA AS252,062$5.3M1.21%+41,24813F-HRTimeline
PFM Health Sciences, LP242,967$5.1M0.52%-13,52113F-HRTimeline
CAPITAL FUND MANAGEMENT S.A.233,871$4.91M0.05%-107,32313F-HRTimeline
CANADA PENSION PLAN INVESTMENT BOARD229,600$4.82M<0.01%013F-HRTimeline
Pinnacle Financial Partners, Inc.in group Pinnacle Financial Partners, …206,601$4.34M0.03%13F-HR/ATimelineGroup
Integral Health Asset Management, LLC200,000$4.2M0.21%new13F-HRTimeline
Vienna Powszechne Towarzystwo Emerytaln…200,000$4.2M2.05%013F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC184,003$3.87M<0.01%-362,26513F-HRTimelineGroup
Hennion & Walsh Asset Management, Inc.183,802$3.86M0.13%+129,10413F-HRTimeline
NOMURA ASSET MANAGEMENT INTERNATIONAL I…in group NOMURA ASSET MANAGEMENT CO LTD180,000$3.78M0.01%13F-HRTimelineGroup
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…165,000$3.47M0.02%-85,00013F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC163,915$3.44M0.04%+31,21413F-HRTimelineGroup
Rafferty Asset Management, LLC161,943$3.4M0.01%+20,12113F-HRTimeline
Swiss National Bank161,400$3.39M<0.01%+2,90013F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN160,850$3.38M<0.01%+103,93413F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.160,525$3.37M<0.01%+27,43413F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO159,638$3.35M<0.01%+116,19013F-HRTimelineGroup
Y-Intercept (Hong Kong) Ltd155,916$3.28M0.07%+55,06513F-HRTimeline
Atom Investors LP141,666$2.98M0.24%new13F-HRTimeline
FMR LLCin group FMR LLC140,560$2.95M<0.01%+135,45913F-HRTimelineGroup
HEALTHCARE OF ONTARIO PENSION PLAN TRUS…137,629$2.89M<0.01%new13F-HRTimeline
Velan Capital Investment Management LP130,000$2.73M1.59%013F-HRTimeline
SG Americas Securities, LLC129,227$2.71M<0.01%+83,80113F-HRTimeline
PANAGORA ASSET MANAGEMENT INC125,099$2.63M0.01%-30,21713F-HRTimeline
Voss Capital, LP125,000$2.63M0.14%new13F-HRTimeline
RHUMBLINE ADVISERS118,799$2.5M<0.01%-12,87013F-HRTimeline
Yelin Lapidot Holdings Management Ltd.in group Yelin Lapidot Holdings Manage…108,377$2.28M0.46%013F-HRTimelineGroup
NEOS Investment Management LLC101,553$2.13M0.01%-8,51313F-HRTimeline
Tema ETFs LLC100,053$2.1M0.16%-10,01313F-HRTimeline
Ishara Investments LP100,000$2.1M2.45%13F-HRTimeline
IEQ CAPITAL, LLC99,876$2.1M0.01%+44,67213F-HRTimeline
Torray Investment Partners LLC97,802$2.05M0.29%new13F-HRTimeline
ALLIANCEBERNSTEIN L.P.94,880$1.99M<0.01%-31,76913F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/94,829$1.99M<0.01%+3,69513F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…89,639$1.88M<0.01%+10,10113F-HRTimelineGroup
Trexquant Investment LP87,514$1.84M0.02%new13F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc78,236$1.64M<0.01%-6,31013F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…78,199$1.64M<0.01%-8813F-HRTimeline
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP75,914$1.59M<0.01%-22,42713F-HRTimelineGroup
DARK FOREST CAPITAL MANAGEMENT LP72,703$1.53M0.07%new13F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\66,608$1.4M<0.01%-5,86213F-HRTimelineGroup
SECTORAL ASSET MANAGEMENT INC61,200$1.29M1.03%-18,23013F-HRTimeline
PROFUND ADVISORS LLC60,038$1.26M0.04%+29,22113F-HRTimeline
Pavaki Capital Management LLC60,000$1.26M0.88%13F-HR/ATimeline
Mariner, LLCin group Mariner, LLC54,987$1.15M<0.01%+31,54713F-HRTimelineGroup
Simplify Asset Management Inc.54,715$1.15M0.02%+26,21013F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC53,582$1.13M<0.01%-29,62513F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding53,268$1.12M+3,097Timeline
TWINBEECH CAPITAL LP52,900$1.11M0.08%+8,60613F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC51,937$1.09M<0.01%-994,51913F-HRTimelineGroup
Palumbo Wealth Management LLC51,368$1.08M0.27%new13F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…49,732$1.04M0.01%013F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL47,421$996K0.01%-2,76313F-HRTimeline
Man Group plcin group Man Group plc44,638$938K<0.01%-130,31313F-HRTimelineGroup
Clearline Capital LP43,413$912K0.07%+9,23613F-HRTimeline
Assenagon Asset Management S.A.41,737$877K<0.01%-1,742,40213F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC65,280$874K<0.01%+10,06613F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC40,793$857K0.01%+6,91813F-HRTimeline
STATE OF WISCONSIN INVESTMENT BOARD40,761$856K<0.01%-9,56913F-HRTimeline
FOX RUN MANAGEMENT, L.L.C.40,302$847K0.13%+4,64613F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson39,335$827K<0.01%013F-HRTimelineGroup
SummitTX Capital, L.P.39,127$822K0.02%-61,45913F-HRTimeline
WESBANCO BANK INC37,000$777K0.02%new13F-HRTimeline
Lion Point Capital, LP36,000$756K3.91%-19,00013F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…35,630$749K<0.01%-2,59613F-HRTimelineGroup
DekaBank Deutsche Girozentrale28,300$710K<0.01%013F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…33,549$705K0.19%+22,88513F-HRTimelineGroup
CWM, LLCin group CWM, LLC31,912$670K<0.01%+10,73713F-HRTimelineGroup
DNB Asset Management ASin group DNB Asset Management AS29,760$625K<0.01%+6,46613F-HRTimelineGroup
Cerity Partners LLCin group Cerity Partners LLC28,856$606K<0.01%+2,08213F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP28,312$595K<0.01%-93,15513F-HRTimelineGroup
Engineers Gate Manager LP26,265$552K0.01%-153,10113F-HRTimeline
SIMPLEX TRADING, LLC25,660$539K0.02%new13F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …25,461$535K<0.01%-3,30313F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND25,384$533K<0.01%013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA25,340$532K<0.01%-202,66013F-HRTimelineGroup
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC24,806$521K<0.01%new13F-HRTimelineGroup
PSP Research LLC24,716$519K0.45%13F-HRTimeline
Creative Planningin group Creative Planning24,711$519K<0.01%+6,74113F-HRTimelineGroup
Walleye Capital LLCin group Walleye Capital LLC24,205$509K<0.01%-273,45313F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC23,741$499K<0.01%+12,07113F-HRTimelineGroup
Police & Firemen's Retirement System of…23,371$491K<0.01%-59713F-HRTimeline
Cetera Investment Advisers23,116$486K<0.01%new13F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC22,731$482K<0.01%-33,79313F-HR/ATimelineGroup
ARIZONA STATE RETIREMENT SYSTEM22,813$479K<0.01%-1,34513F-HRTimeline
Post Resch Tallon Group Inc.22,800$479K0.4%-3,00013F-HRTimeline
GSA CAPITAL PARTNERS LLP22,523$473K0.04%+5,61513F-HRTimeline
Inspire Investing, LLCin group Inspire Investing, LLC22,142$465K0.04%-6,69113F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…20,541$432K<0.01%013F-HRTimeline
Quantinno Capital Management LP20,339$427K<0.01%new13F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC19,814$416K<0.01%-15,70513F-HRTimelineGroup
Bridgefront Capital, LLC19,752$415K0.1%-2,09613F-HRTimeline
WEALTH ENHANCEMENT ADVISORY SERVICES, L…20,195$411K<0.01%+7,31013F-HRTimeline
ProShare Advisors LLC19,388$407K<0.01%+1,74913F-HRTimeline
STATE BOARD OF ADMINISTRATION OF FLORID…18,968$399K<0.01%013F-HRTimeline
HighTower Advisors, LLC18,940$398K<0.01%+1,51713F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd18,476$388K0.01%-11,91713F-HRTimelineGroup
Verition Fund Management LLC18,460$388K<0.01%+1,28113F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…18,153$381K<0.01%-16,59713F-HRTimelineGroup
MERCER GLOBAL ADVISORS INC /ADV17,805$374K<0.01%new13F-HRTimeline
Allspring Global Investments Holdings, …in group Allspring Global Investments …17,562$374K<0.01%+1,45513F-HRTimelineGroup
KLP KAPITALFORVALTNING AS17,600$370K<0.01%+1,00013F-HRTimeline
Entropy Technologies, LP15,064$316K0.02%new13F-HRTimeline
Marex Group Ltdin group Marex Group Ltd15,060$316K<0.01%new13F-HRTimelineGroup
Quadrature Capital Ltdin group Quadrature Capital Ltd14,886$313K<0.01%-17,47413F-HRTimelineGroup
WINTON GROUP Ltdin group WINTON GROUP Ltd14,574$306K0.01%-7,94713F-HRTimelineGroup
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC14,538$305K<0.01%+2,39513F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS14,228$299K<0.01%-585,64313F-HRTimelineGroup
China Universal Asset Management Co., L…14,163$298K0.02%-93613F-HRTimeline
LAZARD ASSET MANAGEMENT LLCin group LAZARD ASSET MANAGEMENT LLC14,140$297K<0.01%new13F-HRTimelineGroup
AlphaQuest LLC13,921$292K0.02%-45,42013F-HRTimeline
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…13,746$289K<0.01%013F-HRTimeline
Schonfeld Strategic Advisors LLC13,100$275K<0.01%-119,02313F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…12,356$260K<0.01%013F-HRTimelineGroup
TEACHER RETIREMENT SYSTEM OF TEXAS12,117$255K<0.01%-7,92013F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC12,000$252K0.02%new13F-HR/ATimelineGroup
GROUP ONE TRADING LLC11,792$248K0.01%new13F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC11,127$234K<0.01%+15813F-HRTimelineGroup
DIVERSIFIED TRUST CO11,109$233K<0.01%new13F-HRTimeline
Pallas Capital Advisors LLC10,985$231K0.01%+87513F-HRTimeline
INCEPTIONR LLC10,747$226K0.06%new13F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC10,169$213K<0.01%+8,47713F-HRTimelineGroup
FARALLON CAPITAL MANAGEMENT, L.L.C.10,000$210K<0.01%013F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
Quarry LP10,000$210K0.03%-25,36513F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC9,707$204K<0.01%new13F-HRTimeline
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co7,182$151K<0.01%013F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…7,119$150K<0.01%013F-HRTimelineGroup
KBC Group NVin group KBC Group NV5,180$109K<0.01%013F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…4,844$102K<0.01%-8,39613F-HRTimelineGroup
Cape Investment Advisory, Inc.4,663$98K0.03%-1,77813F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\4,521$95K<0.01%013F-HRTimelineGroup
AMALGAMATED BANK2,677$56K<0.01%-9813F-HRTimeline
Smartleaf Asset Management LLC2,659$55.1K<0.01%+2,56413F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.2,612$54.9K<0.01%-213F-HRTimelineGroup
Larson Financial Group LLC2,370$49.8K<0.01%-55213F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…2,079$43.7K<0.01%-5913F-HRTimelineGroup
Aquatic Capital Management LLC2,043$42.9K<0.01%new13F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,708$35.9K<0.01%-14513F-HRTimeline
Essential Partners LLC1,455$30.6K0.01%+53213F-HRTimeline
Quantbot Technologies LP1,189$25K<0.01%-2,28213F-HRTimeline
Allworth Financial LP1,129$23.7K<0.01%+38413F-HRTimeline
NISA INVESTMENT ADVISORS, LLC1,112$23.4K<0.01%013F-HRTimeline
MAI Capital Management1,029$21.6K<0.01%+2913F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…987$20.7K<0.01%+37413F-HRTimelineGroup
Sterling Capital Management LLC857$18K<0.01%+27113F-HRTimeline
Versant Capital Management, Inc844$17.7K<0.01%013F-HRTimeline
IFP Advisors, Inc791$16.6K<0.01%+74013F-HRTimeline