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Disclosery

PTGX PROTAGONIST THERAPEUTICS INC

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COM (common), issuer CIK 1377121

240 managers (243 13F filers) reported a position in PTGX shares at 2024-12-31, 63,271,483 shares in all. 39 filers opened a position and 41 filers sold out during the quarter.

Managers
240
13F filers
243
New
39
Added
91
Reduced
76
Sold out
41
Shares held by filers
63,271,483

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2024

Filers in the available 13F reports with a share position at 2024-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
BlackRock, Inc.in group BlackRock, Inc.9,884,617$382M0.01%-339,67813F-HRTimelineGroup
FARALLON CAPITAL MANAGEMENT, L.L.C.5,930,006$229M1.21%+69,00013F-HRTimeline
RTW INVESTMENTS, LP5,498,545$212M3.21%+72,43313F-HRTimeline
VANGUARD GROUP INCin group VANGUARD GROUP INC4,220,037$163M<0.01%+3,95613F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP3,331,061$129M0.01%+147,51913F-HRTimelineGroup
JOHNSON & JOHNSONin group JOHNSON & JOHNSON2,449,183$94.5M24.48%013F-HRTimelineGroup
BVF INC/ILin group BVF INC/IL1,900,015$73.3M2.49%+49,84813F-HRTimelineGroup
Pacer Advisors, Inc.1,876,466$72.4M0.16%+142,37613F-HRTimeline
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.1,489,495$57.5M0.64%-325,20113F-HR/ATimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/1,392,652$53.8M0.01%+83,18513F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,377,063$53.2M<0.01%+2,36613F-HRTimelineGroup
PERCEPTIVE ADVISORS LLCin group PERCEPTIVE ADVISORS LLC1,271,662$49.1M1.37%-102,90113F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC1,020,333$39.4M8.12%+39,03813F-HRTimelineGroup
Deep Track Capital, LP1,000,000$38.6M1.45%new13F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…940,077$36.3M0.01%+909,99813F-HRTimelineGroup
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC928,286$35.8M0.02%+353,51113F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC758,690$29.3M0.01%-63,16613F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.738,952$28.5M0.01%+85,80013F-HRTimelineGroup
Eversept Partners, LP678,787$26.2M2.7%+233,58313F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP628,580$24.3M<0.01%+48,49113F-HRTimelineGroup
Woodline Partners LP582,327$22.5M0.15%+115,80913F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co578,409$22.3M<0.01%+12,90613F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO576,977$22.3M<0.01%+73,99213F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY540,315$20.9M<0.01%-88,30813F-HR/ATimelineGroup
FMR LLCin group FMR LLC442,516$17.1M<0.01%-11,68013F-HRTimelineGroup
Focus Partners Wealthin group Focus Partners Wealth425,557$16.4M0.04%-1,10413F-HR/ATimelineGroup
UBS Group AGgroup of 2 filers holding420,520$16.2M-26,411Timeline
683 Capital Management, LLCin group 683 Capital Management, LLC410,000$15.8M1.56%-10,00013F-HRTimelineGroup
MANGROVE PARTNERS IM, LLC395,383$15.3M1.82%-43,93113F-HRTimeline
Kynam Capital Management, LP390,792$15.1M1%-65,57713F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp390,788$15.1M<0.01%+34,45513F-HRTimelineGroup
Polar Capital Holdings Plcin group Polar Capital Holdings Plc350,000$13.5M0.08%013F-HRTimelineGroup
TORONTO DOMINION BANKin group TORONTO DOMINION BANK340,974$13.2M0.03%new13F-HR/ATimelineGroup
Driehaus Capital Management LLC339,698$13.1M0.11%-105,65413F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCgroup of 2 filers holding337,821$13M+16,974Timeline
KENNEDY CAPITAL MANAGEMENT LLC321,526$12.4M0.28%+54,49313F-HRTimeline
Qube Research & Technologies Ltd312,319$12.1M0.02%-10,67013F-HRTimeline
Skandinaviska Enskilda Banken AB (publ)310,650$12M0.05%+80,53613F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC303,313$11.7M<0.01%13F-HR/ATimelineGroup
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…296,511$11.4M0.01%+289,21313F-HRTimelineGroup
Artia Global Partners LP293,851$11.3M4.57%+169,41113F-HRTimeline
Soleus Capital Management, L.P.275,000$10.6M0.8%new13F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC240,817$9.3M0.01%+110,02013F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP225,600$8.71M<0.01%+1113F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC221,167$8.54M0.01%+77,00013F-HRTimeline
ARROWSTREET CAPITAL, LIMITED PARTNERSHIPin group ARROWSTREET CAPITAL, LIMITED …216,069$8.34M0.01%+58,00213F-HRTimelineGroup
TD Asset Management Inc173,702$6.7M0.01%+1,50013F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC164,146$6.34M0.01%+159,11613F-HRTimelineGroup
RHUMBLINE ADVISERS161,964$6.25M0.01%-2,21413F-HR/ATimeline
Man Group plcin group Man Group plc157,963$6.1M0.02%+102,13213F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc152,562$5.89M<0.01%-44413F-HRTimelineGroup
Nuveen Asset Management, LLCin group TIAA151,197$5.84M<0.01%-80,87713F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC150,097$5.79M0.01%+12,92613F-HRTimelineGroup
Public Sector Pension Investment Board148,489$5.73M0.02%+23,54013F-HRTimeline
STEMPOINT CAPITAL LP141,714$5.47M1.37%new13F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC141,387$5.46M<0.01%-2,42013F-HRTimelineGroup
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP140,951$5.44M<0.01%+2713F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\137,932$5.32M<0.01%+17,76313F-HR/ATimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/134,872$5.21M<0.01%-18,64513F-HRTimelineGroup
Affinity Asset Advisors, LLC130,000$5.02M0.78%new13F-HRTimeline
JACOBS LEVY EQUITY MANAGEMENT, INC128,654$4.97M0.02%013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC126,733$4.89M<0.01%-26213F-HR/ATimelineGroup
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …125,898$4.86M0.01%013F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …124,341$4.8M<0.01%+8,57613F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC121,022$4.67M<0.01%+47,53213F-HRTimelineGroup
HUSSMAN STRATEGIC ADVISORS, INC.105,000$4.05M1.2%new13F-HRTimeline
Opaleye Management Inc.105,000$4.05M0.71%013F-HRTimeline
Caption Management, LLC98,934$3.82M0.16%+76,83413F-HRTimeline
Rafferty Asset Management, LLC95,467$3.69M0.01%+5,59113F-HRTimeline
Trexquant Investment LP92,788$3.58M0.04%+69,69713F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources88,870$3.43M<0.01%+7,27913F-HRTimelineGroup
Swiss National Bank86,900$3.35M<0.01%+1,00013F-HRTimeline
SILVERCREST ASSET MANAGEMENT GROUP LLC84,426$3.26M0.02%-82813F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC82,627$3.19M<0.01%-31,22513F-HR/ATimelineGroup
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…78,894$3.05M<0.01%013F-HRTimelineGroup
Aquilo Capital Management, LLC76,592$2.96M5.06%new13F-HRTimeline
E Fund Management Co., Ltd.76,087$2.94M0.15%+4,42113F-HRTimeline
Ikarian Capital, LLCin group Ikarian Capital, LLC70,000$2.7M0.77%new13F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…69,937$2.7M<0.01%+29,58013F-HRTimelineGroup
SUPERSTRING CAPITAL MANAGEMENT LP68,892$2.66M2.34%new13F-HRTimeline
ALLIANCEBERNSTEIN L.P.68,225$2.63M<0.01%-13,69413F-HRTimeline
Moody Aldrich Partners LLC67,415$2.6M0.48%-51,87213F-HRTimeline
HighVista Strategies LLC62,518$2.41M0.9%-26,99013F-HRTimeline
GREAT LAKES ADVISORS, LLC61,947$2.39M0.02%-7,67813F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC61,551$2.38M<0.01%+28,69313F-HRTimelineGroup
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC59,998$2.32M<0.01%-80013F-HRTimelineGroup
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co56,536$2.18M<0.01%013F-HRTimelineGroup
ALPS ADVISORS INCin group ALPS ADVISORS INC55,941$2.16M0.01%+3,90913F-HRTimelineGroup
Knott David M Jr52,368$2.02M0.73%013F-HRTimeline
Assenagon Asset Management S.A.52,239$2.02M<0.01%new13F-HRTimeline
STATE OF WISCONSIN INVESTMENT BOARD50,782$1.96M0.01%+3,62213F-HRTimeline
Swedbank ABin group Swedbank AB50,000$1.93M<0.01%013F-HRTimelineGroup
Birchview Capital, LP48,000$1.85M1.51%013F-HR/ATimeline
Thrivent Financial for Lutheransin group Thrivent Financial for Luther…46,066$1.78M<0.01%-19113F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…42,349$1.63M<0.01%-31613F-HR/ATimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding39,041$1.51M+1,406Timeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN38,796$1.5M<0.01%+9,42313F-HRTimelineGroup
Quantedge Capital Pte Ltd37,200$1.44M0.52%+4,21713F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…35,798$1.38M0.01%+1,99313F-HRTimelineGroup
State of Alaska, Department of Revenue33,871$1.31M0.01%+25613F-HRTimeline
Illinois Municipal Retirement Fund33,509$1.29M0.02%+4,38513F-HRTimeline
MASSACHUSETTS FINANCIAL SERVICES CO /MA/in group MASSACHUSETTS FINANCIAL SERVI…32,449$1.25M<0.01%new13F-HRTimelineGroup
Hennion & Walsh Asset Management, Inc.32,074$1.24M0.06%-5,33913F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC31,480$1.22M0.01%+12,35213F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC31,366$1.21M<0.01%+8,92013F-HRTimeline
Cavalier Investments, LLC31,252$1.21M0.4%+1,29613F-HRTimeline
Corebridge Financial, Inc.in group Corebridge Financial, Inc.31,155$1.2M0.01%-2,40713F-HRTimelineGroup
ExodusPoint Capital Management, LP29,870$1.15M0.01%new13F-HRTimeline
Louisiana State Employees Retirement Sy…28,800$1.11M0.02%+30013F-HRTimeline
CAPITAL FUND MANAGEMENT S.A.28,058$1.08M0.01%new13F-HRTimeline
State of Tennessee, Department of Treas…27,076$1.05M<0.01%-66713F-HRTimeline
Ensign Peak Advisors, Inc27,036$1.04M<0.01%013F-HRTimeline
WINTON GROUP Ltdin group WINTON GROUP Ltd26,768$1.03M0.07%+78513F-HRTimelineGroup
NEW YORK STATE TEACHERS RETIREMENT SYST…24,592$949K<0.01%013F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO24,568$948K<0.01%-10,51013F-HRTimelineGroup
Bellevue Group AGin group Bellevue Group AG23,718$916K0.02%+11,37213F-HRTimelineGroup
Summit Global Investmentsin group Summit Global Investments23,557$909K0.06%new13F-HRTimelineGroup
STRS OHIO23,500$907K<0.01%+2,00013F-HRTimeline
YOUSIF CAPITAL MANAGEMENT, LLC22,918$885K0.01%-32213F-HRTimeline
SIERRA SUMMIT ADVISORS LLC22,282$860K0.17%+1,11513F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson21,454$828K<0.01%013F-HRTimelineGroup
MACKENZIE FINANCIAL CORP21,349$824K<0.01%+13,57513F-HR/ATimeline
Tidal Investments LLCin group Tidal Investments LLC21,012$811K0.01%-1,05013F-HRTimelineGroup
PROFUND ADVISORS LLC20,649$797K0.03%+56613F-HRTimeline
COMERICA BANK20,558$794K<0.01%-34613F-HR/ATimeline
ProShare Advisors LLC20,457$790K<0.01%+4,77613F-HRTimeline
TEACHERS RETIREMENT SYSTEM OF THE STATE…20,200$780K0.01%013F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC20,188$779K0.02%new13F-HRTimeline
Maryland State Retirement & Pension Sys…20,170$779K0.02%+27813F-HRTimeline
BRAIDWELL LP20,109$776K0.02%new13F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP19,716$761K<0.01%-295,65713F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS19,465$751K<0.01%-82913F-HRTimelineGroup
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC19,078$736K0.01%+11,18013F-HRTimelineGroup
Mariner, LLCin group Mariner, LLC17,983$694K<0.01%+2,00413F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND17,882$690K<0.01%-2,30013F-HR/ATimeline
ALGERT GLOBAL LLC17,720$684K0.02%-97,95913F-HR/ATimeline
Handelsbanken Fonder AB17,600$679K<0.01%new13F-HRTimeline
AMALGAMATED BANK17,405$672K0.01%+8113F-HRTimeline
STATE BOARD OF ADMINISTRATION OF FLORID…16,303$629K<0.01%013F-HRTimeline
Moran Wealth Management, LLC15,961$616K0.02%+93113F-HRTimeline
DekaBank Deutsche Girozentrale15,800$610K<0.01%013F-HRTimeline
AVIVA PLCin group AVIVA PLC14,627$565K<0.01%new13F-HRTimelineGroup
OREGON PUBLIC EMPLOYEES RETIREMENT FUND14,000$540K0.01%+10013F-HRTimeline
Erste Asset Management GmbHin group Erste Asset Management GmbH13,500$526K0.01%new13F-HRTimelineGroup
Cerity Partners LLCin group Cerity Partners LLC13,056$518K<0.01%-1,18513F-HRTimelineGroup
TEACHER RETIREMENT SYSTEM OF TEXAS13,099$506K<0.01%+2,06713F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM12,805$494K<0.01%+13913F-HRTimeline
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCH…12,723$491K<0.01%+13213F-HRTimeline
Crestline Management, L.P.12,681$489K0.02%new13F-HRTimeline
China Universal Asset Management Co., L…12,637$488K0.05%+1,30813F-HRTimeline
Police & Firemen's Retirement System of…12,441$480K<0.01%13F-HRTimeline
Scientech Research LLC12,054$465K0.13%-2,47313F-HRTimeline
FRANKLIN STREET ADVISORS INC /NC11,300$436K0.03%-10013F-HRTimeline
Allianz Asset Management GmbHin group Allianz SE11,000$425K<0.01%-8,30013F-HRTimelineGroup
Cambria Investment Management, L.P.10,575$408K0.02%new13F-HRTimeline
Inspire Investing, LLCin group Inspire Investing, LLC10,555$407K0.05%-25,95913F-HRTimelineGroup
Cache Advisors, LLC10,143$392K0.16%13F-HR/ATimeline
Zurcher Kantonalbank (Zurich Cantonalba…9,702$374K<0.01%-12613F-HRTimeline
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLCin group MUTUAL OF AMERICA CAPITAL MAN…9,027$348K<0.01%+16713F-HRTimelineGroup
PEAK6 LLCin group PEAK6 LLC9,000$347K0.01%13F-HRTimelineGroup
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC8,981$347K<0.01%-3,80213F-HRTimelineGroup
GLENMEDE TRUST CO NAin group GLENMEDE TRUST CO NA8,953$346K<0.01%-6,02813F-HRTimelineGroup
KLP KAPITALFORVALTNING AS8,700$336K<0.01%13F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC8,128$313K<0.01%+2,25913F-HRTimelineGroup
HRT FINANCIAL LP8,025$309K<0.01%new13F-HRTimeline
State of Wyoming7,832$302K0.04%+83213F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA7,630$295K<0.01%-5,93313F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…7,369$284K0.01%+7,00913F-HRTimelineGroup
AlphaCentric Advisors LLC7,123$275K0.27%-17,87713F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd6,744$260K0.02%-8,05713F-HRTimelineGroup
Freestone Grove Partners LP6,644$256K<0.01%13F-HRTimeline
CONTRAVISORY INVESTMENT MANAGEMENT, INC.6,498$251K0.05%new13F-HRTimeline
Creative Planningin group Creative Planning6,448$249K<0.01%-1,05613F-HRTimelineGroup
Bleakley Financial Group, LLC6,367$246K0.01%-66413F-HRTimeline
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/6,250$241K<0.01%+27013F-HRTimelineGroup
King Wealth Management Group6,000$232K0.03%013F-HRTimeline
Allspring Global Investments Holdings, …in group Allspring Global Investments …5,975$231K<0.01%-97,86713F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…5,912$228K0.01%013F-HRTimelineGroup
CAPTRUST FINANCIAL ADVISORS5,878$227K<0.01%-24813F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC5,889$226K<0.01%+3,50213F-HRTimelineGroup
Caprock Group, LLC5,802$224K0.01%new13F-HRTimeline
Advantage Alpha Capital Partners LP5,742$222K0.05%-5,59413F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.5,704$220K<0.01%-21,12113F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding5,658$218K-12,153Timeline
Kestra Advisory Services, LLCin group Kestra Advisory Services, LLC5,647$218K<0.01%+46413F-HRTimelineGroup
TWO SIGMA SECURITIES, LLC5,505$212K0.04%new13F-HRTimeline
CIBC WORLD MARKETS CORP5,468$211K<0.01%new13F-HRTimeline
SIMPLEX TRADING, LLC5,487$211K0.01%new13F-HRTimeline
Cornerstone Investment Partners, LLC5,416$209K0.01%-513F-HRTimeline
NISA INVESTMENT ADVISORS, LLC3,133$121K<0.01%+29513F-HRTimeline
New Vernon Capital Holdings II LLCin group New Vernon Capital Holdings I…3,061$118K0.08%new13F-HRTimelineGroup
Advisors Asset Management, Inc.2,598$100K<0.01%new13F-HR/ATimeline
AlphaQuest LLC2,177$84K0.01%-21,77013F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\2,130$82.2K<0.01%-5,73613F-HRTimelineGroup
KBC Group NVin group KBC Group NV2,093$81K<0.01%+73713F-HRTimelineGroup
Amundiin group Amundi2,033$76.5K<0.01%013F-HRTimelineGroup
VIRTUS ADVISERS, LLCin group Virtus Investment Advisers, L…1,761$68K0.03%-91913F-HRTimelineGroup
Covestor Ltd1,643$63K0.04%+1,61213F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…1,441$55.6K<0.01%-28813F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.1,251$48.3K<0.01%13F-HRTimeline