FMR LLC in group FMR LLC More: the full row for FMR LLC 4,303,188 $310M 0.02% +4,202,059 13F-HR Timeline Group BVF INC/IL in group BVF INC/IL More: the full row for BVF INC/IL 2,559,595 $184M 5.87% +1,000,000 13F-HR Timeline Group Two Seas Capital LP in group Two Seas Capital LP More: the full row for Two Seas Capital LP 1,959,178 $141M 6.51% +1,213,993 13F-HR Timeline Group VANGUARD GROUP INC group of 7 filers holding More: the full row for VANGUARD GROUP INC 1,476,064 $106M new Timeline VANGUARD CAPITAL MANAGEMENT LLC : 1,197,055 (<0.01%) 13F-HR/A VANGUARD FIDUCIARY TRUST CO : 169,308 (<0.01%) 13F-HR VANGUARD PORTFOLIO MANAGEMENT LLC : 72,491 (<0.01%) 13F-HR VANGUARD ASSET MANAGEMENT, Ltd : 15,916 (<0.01%) 13F-HR Vanguard Global Advisers, LLC : 11,254 (<0.01%) 13F-HR Vanguard Investments Australia, L… : 6,355 (<0.01%) 13F-HR Vanguard Personalized Indexing Ma… : 3,685 (<0.01%) 13F-HR TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 930,741 $67M 0.06% +457,727 13F-HR Timeline Group Prosight Management, LP More: the full row for Prosight Management, LP 735,000 $52.9M 8.67% +180,367 13F-HR Timeline BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 692,650 $49.8M <0.01% +47,043 13F-HR Timeline Group MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 659,387 $47.4M <0.01% +92,966 13F-HR Timeline Group EMERALD ADVISERS, LLC group of 2 filers holding More: the full row for EMERALD ADVISERS, LLC 650,710 $46.8M +13,243 Timeline ARMISTICE CAPITAL, LLC More: the full row for ARMISTICE CAPITAL, LLC 578,000 $41.6M 1.37% -18,000 13F-HR Timeline Invesco Ltd. in group Invesco Ltd. More: the full row for Invesco Ltd. 567,458 $40.8M <0.01% +99,299 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 513,531 $36.9M 0.03% +203,754 13F-HR Timeline Group Sofinnova Investments, Inc. More: the full row for Sofinnova Investments, Inc. 509,546 $36.7M 1.84% +70,916 13F-HR Timeline Woodline Partners LP More: the full row for Woodline Partners LP 415,335 $29.9M 0.11% +311,335 13F-HR/A Timeline LORD, ABBETT & CO. LLC More: the full row for LORD, ABBETT & CO. LLC 405,080 $29.1M 0.1% new 13F-HR Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 404,277 $29.1M 0.02% -49,798 13F-HR Timeline Group Qube Research & Technologies Ltd More: the full row for Qube Research & Technologies Ltd 390,675 $28.1M 0.04% +66,760 13F-HR Timeline UBS Group AG group of 2 filers holding More: the full row for UBS Group AG 354,197 $25.5M +50,452 Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 346,795 $25M <0.01% +92,434 13F-HR Timeline Group GREAT POINT PARTNERS LLC More: the full row for GREAT POINT PARTNERS LLC 316,453 $22.8M 5.58% +105,721 13F-HR Timeline Vestal Point Capital, LP More: the full row for Vestal Point Capital, LP 285,000 $20.5M 0.57% new 13F-HR Timeline SUSQUEHANNA INTERNATIONAL GROUP, LLP group of 2 filers holding More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 283,617 $20.4M -115,750 Timeline 22NW, LP More: the full row for 22NW, LP 281,115 $20.2M 15.92% -50,000 13F-HR Timeline PRIMECAP MANAGEMENT CO/CA/ More: the full row for PRIMECAP MANAGEMENT CO/CA/ 279,150 $20.1M 0.02% -1,000 13F-HR Timeline ORBIMED ADVISORS LLC in group ORBIMED ADVISORS LLC More: the full row for ORBIMED ADVISORS LLC 275,000 $19.8M 0.43% new 13F-HR Timeline Group GILDER GAGNON HOWE & CO LLC More: the full row for GILDER GAGNON HOWE & CO LLC 271,758 $19.6M 0.23% +63,456 13F-HR Timeline Nearwater Capital Markets, Ltd More: the full row for Nearwater Capital Markets, Ltd 261,500 $18.8M 0.44% +200,000 13F-HR Timeline STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 244,727 $17.6M <0.01% +49,071 13F-HR Timeline Group Deeter Investments LLP More: the full row for Deeter Investments LLP 239,300 $17.2M 3.02% new 13F-HR Timeline BRAIDWELL LP More: the full row for BRAIDWELL LP 222,701 $16M 0.53% new 13F-HR Timeline JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 240,102 $15.7M <0.01% +89,298 13F-HR/A Timeline Group Patient Square Capital LP More: the full row for Patient Square Capital LP 210,000 $15.1M 2.68% new 13F-HR Timeline Bronte Capital Management Pty Ltd. More: the full row for Bronte Capital Management Pty Ltd. 198,256 $14.3M 1.52% new 13F-HR Timeline Quinn Opportunity Partners LLC More: the full row for Quinn Opportunity Partners LLC 179,247 $12.9M 0.68% +93,379 13F-HR Timeline CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 168,007 $12.1M <0.01% +47,627 13F-HR Timeline Group DAFNA Capital Management LLC More: the full row for DAFNA Capital Management LLC 165,178 $11.9M 2.7% +90,180 13F-HR Timeline ADAR1 Capital Management, LLC in group ADAR1 Capital Management, LLC More: the full row for ADAR1 Capital Management, LLC 161,252 $11.6M 0.7% +89,221 13F-HR Timeline Group MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 140,588 $10.1M 0.01% +116,565 13F-HR Timeline Group AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 136,730 $9.84M <0.01% new 13F-HR/A Timeline Group GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 126,942 $9.13M <0.01% -20,851 13F-HR Timeline Group Creek Drive Management Group LLC More: the full row for Creek Drive Management Group LLC 126,400 $9.09M 5.7% -59,100 13F-HR Timeline SEVEN GRAND MANAGERS, LLC More: the full row for SEVEN GRAND MANAGERS, LLC 125,000 $8.99M 0.6% new 13F-HR Timeline Squadron Capital Management LLC More: the full row for Squadron Capital Management LLC 125,000 $8.99M 3.6% new 13F-HR Timeline Nationale-Nederlanden Powszechne Towarz… More: the full row for Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. 122,326 $8.8M 0.75% -65,786 13F-HR Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 121,539 $8.74M 0.01% -88,759 13F-HR Timeline Group JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 112,652 $8.11M 0.01% -105,685 13F-HR Timeline Group Squarepoint Ops LLC in group Squarepoint Ops LLC More: the full row for Squarepoint Ops LLC 107,385 $7.73M 0.02% +87,128 13F-HR Timeline Group Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 106,248 $7.64M 0.01% +20,582 13F-HR Timeline Group Tetragon Partners GP Ltd in group Tetragon Partners GP Ltd More: the full row for Tetragon Partners GP Ltd 103,037 $7.41M 1.46% +33,750 13F-HR Timeline Group ING GROEP NV More: the full row for ING GROEP NV 100,000 $7.2M 0.04% 0 13F-HR Timeline Monashee Investment Management LLC More: the full row for Monashee Investment Management LLC 100,000 $7.2M 3.91% +5,866 13F-HR Timeline Connor, Clark & Lunn Investment Managem… More: the full row for Connor, Clark & Lunn Investment Management Ltd. 98,745 $7.1M 0.02% -2,421 13F-HR Timeline DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 91,671 $6.6M <0.01% +928 13F-HR Timeline Group Moody Aldrich Partners LLC More: the full row for Moody Aldrich Partners LLC 89,527 $6.44M 1.16% +33,504 13F-HR Timeline Stonepine Capital Management, LLC More: the full row for Stonepine Capital Management, LLC 85,000 $6.12M 5.38% 0 13F-HR Timeline NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 78,598 $5.66M <0.01% +22,522 13F-HR Timeline Group Jump Financial, LLC in group Jump Financial, LLC More: the full row for Jump Financial, LLC 77,402 $5.57M 0.08% +24,190 13F-HR Timeline Group ACT CAPITAL MANAGEMENT, LLC More: the full row for ACT CAPITAL MANAGEMENT, LLC 70,900 $5.1M 4.01% +19,700 13F-HR Timeline HRT FINANCIAL LP More: the full row for HRT FINANCIAL LP 70,667 $5.08M 0.01% -102,776 13F-HR Timeline Voleon Capital Management LP More: the full row for Voleon Capital Management LP 65,063 $4.68M 0.1% -3,272 13F-HR Timeline F/m Investments LLC More: the full row for F/m Investments LLC 61,104 $4.4M 0.29% +2,981 13F-HR Timeline Rhenman & Partners Asset Management AB More: the full row for Rhenman & Partners Asset Management AB 59,000 $4.25M 0.52% new 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 58,958 $4.24M <0.01% +32,866 13F-HR Timeline Group Aquatic Capital Management LLC More: the full row for Aquatic Capital Management LLC 57,014 $4.1M 0.12% +1,774 13F-HR Timeline Cambridge Investment Research Advisors,… More: the full row for Cambridge Investment Research Advisors, Inc. 56,055 $4.03M 0.01% +2,342 13F-HR Timeline Trexquant Investment LP More: the full row for Trexquant Investment LP 55,476 $3.99M 0.03% +36,655 13F-HR Timeline FRED ALGER MANAGEMENT, LLC in group FRED ALGER MANAGEMENT, LLC More: the full row for FRED ALGER MANAGEMENT, LLC 53,172 $3.83M 0.02% -848 13F-HR Timeline Group Alyeska Investment Group, L.P. in group Alyeska Investment Group, L.P. More: the full row for Alyeska Investment Group, L.P. 50,000 $3.6M 0.01% new 13F-HR Timeline Group Brevan Howard Capital Management LP in group Brevan Howard Capital Managem… More: the full row for Brevan Howard Capital Management LP 48,474 $3.49M 0.03% new 13F-HR Timeline Group LMR Partners LLP in group LMR Partners LLP More: the full row for LMR Partners LLP 48,294 $3.47M 0.03% new 13F-HR Timeline Group Swiss National Bank More: the full row for Swiss National Bank 47,900 $3.45M <0.01% +16,000 13F-HR Timeline Atom Investors LP More: the full row for Atom Investors LP 43,227 $3.11M 0.22% new 13F-HR Timeline SummitTX Capital, L.P. More: the full row for SummitTX Capital, L.P. 42,624 $3.07M 0.1% +11,271 13F-HR Timeline RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 41,781 $3.01M <0.01% -131,100 13F-HR Timeline LANDSCAPE CAPITAL MANAGEMENT, L.L.C. in group LANDSCAPE CAPITAL MANAGEMENT,… More: the full row for LANDSCAPE CAPITAL MANAGEMENT, L.L.C. 36,907 $2.66M 0.17% -23,524 13F-HR Timeline Group Jain Global LLC More: the full row for Jain Global LLC 36,181 $2.6M 0.03% +18,882 13F-HR Timeline Informed Momentum Co LLC More: the full row for Informed Momentum Co LLC 36,126 $2.6M 0.3% +23,154 13F-HR Timeline Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 35,851 $2.58M 0.01% -246,170 13F-HR Timeline Group ALGERT GLOBAL LLC More: the full row for ALGERT GLOBAL LLC 34,782 $2.5M 0.04% +19,472 13F-HR/A Timeline BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 32,356 $2.33M <0.01% +16,912 13F-HR Timeline Group IRIDIAN ASSET MANAGEMENT LLC/CT More: the full row for IRIDIAN ASSET MANAGEMENT LLC/CT 31,320 $2.25M 0.91% +21,592 13F-HR Timeline Birchview Capital, LP More: the full row for Birchview Capital, LP 31,000 $2.23M 1.27% 0 13F-HR Timeline JACOBS LEVY EQUITY MANAGEMENT, INC More: the full row for JACOBS LEVY EQUITY MANAGEMENT, INC 30,141 $2.17M 0.01% +15,577 13F-HR Timeline CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 28,682 $2.06M <0.01% +14,162 13F-HR Timeline Headlands Technologies LLC More: the full row for Headlands Technologies LLC 28,244 $2.03M 0.23% -12,957 13F-HR Timeline KVP Capital Advisors, LP More: the full row for KVP Capital Advisors, LP 26,900 $1.94M 1.45% 0 13F-HR Timeline Y-Intercept (Hong Kong) Ltd More: the full row for Y-Intercept (Hong Kong) Ltd 26,545 $1.91M 0.04% +15,683 13F-HR Timeline Erste Asset Management GmbH in group Erste Asset Management GmbH More: the full row for Erste Asset Management GmbH 28,000 $1.83M 0.02% 0 13F-HR Timeline Group CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 25,048 $1.8M <0.01% -10,729 13F-HR Timeline Group GSA CAPITAL PARTNERS LLP More: the full row for GSA CAPITAL PARTNERS LLP 21,331 $1.53M 0.1% -1,783 13F-HR Timeline BIT Capital GmbH More: the full row for BIT Capital GmbH 21,100 $1.52M 0.08% 0 13F-HR Timeline ExodusPoint Capital Management, LP More: the full row for ExodusPoint Capital Management, LP 20,457 $1.47M 0.01% new 13F-HR Timeline AWM Investment Company, Inc. More: the full row for AWM Investment Company, Inc. 20,000 $1.44M 0.16% -20,000 13F-HR Timeline Man Group plc in group Man Group plc More: the full row for Man Group plc 19,446 $1.4M <0.01% new 13F-HR Timeline Group Deuterium Capital Management, LLC More: the full row for Deuterium Capital Management, LLC 18,000 $1.3M 1.51% -19,349 13F-HR Timeline WINTON GROUP Ltd in group WINTON GROUP Ltd More: the full row for WINTON GROUP Ltd 16,910 $1.22M 0.04% +9,145 13F-HR Timeline Group Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 16,658 $1.2M <0.01% +4,245 13F-HR Timeline Group IMC-Chicago, LLC More: the full row for IMC-Chicago, LLC 16,361 $1.18M 0.02% new 13F-HR Timeline ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 16,181 $1.16M <0.01% +9,176 13F-HR Timeline Group HEALTHCARE OF ONTARIO PENSION PLAN TRUS… More: the full row for HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 15,813 $1.14M <0.01% new 13F-HR Timeline Steward Partners Investment Advisory, L… More: the full row for Steward Partners Investment Advisory, LLC 15,526 $1.12M 0.01% +15,313 13F-HR Timeline TUDOR INVESTMENT CORP ET AL More: the full row for TUDOR INVESTMENT CORP ET AL 14,984 $1.08M 0.01% new 13F-HR Timeline HighVista Strategies LLC More: the full row for HighVista Strategies LLC 14,555 $1.05M 0.29% +2,806 13F-HR Timeline GLENMEDE TRUST CO NA in group GLENMEDE TRUST CO NA More: the full row for GLENMEDE TRUST CO NA 13,865 $998K <0.01% +5,275 13F-HR Timeline Group STATE OF WISCONSIN INVESTMENT BOARD More: the full row for STATE OF WISCONSIN INVESTMENT BOARD 13,670 $984K <0.01% +5,041 13F-HR Timeline Point72 Asset Management, L.P. in group Point72 Asset Management, L.P. More: the full row for Point72 Asset Management, L.P. 13,364 $962K <0.01% -420,055 13F-HR Timeline Group Walleye Capital LLC in group Walleye Capital LLC More: the full row for Walleye Capital LLC 12,878 $927K 0.01% new 13F-HR/A Timeline Group Engineers Gate Manager LP More: the full row for Engineers Gate Manager LP 12,302 $885K 0.01% -24,982 13F-HR Timeline FIFTH LANE CAPITAL, LP More: the full row for FIFTH LANE CAPITAL, LP 12,000 $863K 1.05% new 13F-HR Timeline SECTORAL ASSET MANAGEMENT INC More: the full row for SECTORAL ASSET MANAGEMENT INC 10,851 $821K 0.68% -2,634 13F-HR Timeline PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 11,276 $812K <0.01% +900 13F-HR Timeline Scientech Research LLC More: the full row for Scientech Research LLC 11,032 $794K 0.66% new 13F-HR Timeline ENVESTNET ASSET MANAGEMENT INC in group ENVESTNET ASSET MANAGEMENT INC More: the full row for ENVESTNET ASSET MANAGEMENT INC 10,883 $783K <0.01% +5,499 13F-HR Timeline Group JANUS HENDERSON GROUP PLC in group Janus Henderson More: the full row for JANUS HENDERSON GROUP PLC 10,729 $771K <0.01% +2,629 13F-HR/A Timeline Group OCCUDO QUANTITATIVE STRATEGIES LP More: the full row for OCCUDO QUANTITATIVE STRATEGIES LP 8,948 $761K 0.04% new 13F-HR Timeline Hudson Bay Capital Management LP in group Hudson Bay Capital Management… More: the full row for Hudson Bay Capital Management LP 10,332 $743K <0.01% -49,359 13F-HR Timeline Group Palumbo Wealth Management LLC More: the full row for Palumbo Wealth Management LLC 10,173 $732K 0.18% -4,541 13F-HR Timeline ALLSTATE CORP in group ALLSTATE CORP More: the full row for ALLSTATE CORP 9,837 $708K 0.01% new 13F-HR Timeline Group State of New Jersey Common Pension Fund… in group State of New Jersey Common Pe… More: the full row for State of New Jersey Common Pension Fund D 8,288 $596K <0.01% new 13F-HR Timeline Group Schonfeld Strategic Advisors LLC More: the full row for Schonfeld Strategic Advisors LLC 8,063 $580K <0.01% new 13F-HR Timeline Diametric Capital, LP More: the full row for Diametric Capital, LP 7,411 $533K 0.14% new 13F-HR Timeline CenterBook Partners LP More: the full row for CenterBook Partners LP 7,407 $533K 0.03% new 13F-HR Timeline PEAK6 LLC in group PEAK6 LLC More: the full row for PEAK6 LLC 7,000 $504K 0.01% new 13F-HR Timeline Group Catalyst Funds Management Pty Ltd More: the full row for Catalyst Funds Management Pty Ltd 6,700 $482K 0.08% new 13F-HR Timeline Zurcher Kantonalbank (Zurich Cantonalba… More: the full row for Zurcher Kantonalbank (Zurich Cantonalbank) 6,695 $482K <0.01% new 13F-HR Timeline ARIZONA STATE RETIREMENT SYSTEM More: the full row for ARIZONA STATE RETIREMENT SYSTEM 6,661 $479K <0.01% new 13F-HR Timeline Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 6,597 $475K <0.01% new 13F-HR Timeline Group Neo Ivy Capital Management More: the full row for Neo Ivy Capital Management 6,439 $463K 0.12% new 13F-HR Timeline FOX RUN MANAGEMENT, L.L.C. More: the full row for FOX RUN MANAGEMENT, L.L.C. 6,871 $448K 0.08% -19,651 13F-HR Timeline GROUP ONE TRADING LLC More: the full row for GROUP ONE TRADING LLC 5,949 $428K 0.01% +4,501 13F-HR Timeline Persistent Asset Partners Ltd More: the full row for Persistent Asset Partners Ltd 5,820 $419K 0.16% new 13F-HR Timeline SIMPLEX TRADING, LLC More: the full row for SIMPLEX TRADING, LLC 5,722 $412K 0.01% -16,214 13F-HR Timeline KLP KAPITALFORVALTNING AS More: the full row for KLP KAPITALFORVALTNING AS 5,200 $374K <0.01% +1,700 13F-HR Timeline Gainplan LLC More: the full row for Gainplan LLC 5,000 $360K 0.27% -8,500 13F-HR Timeline Virtus Investment Advisers, LLC in group Virtus Investment Advisers, L… More: the full row for Virtus Investment Advisers, LLC 4,984 $359K 0.1% +121 13F-HR Timeline Group FNY Investment Advisers, LLC More: the full row for FNY Investment Advisers, LLC 4,750 $341K 0.15% -450 13F-HR Timeline Entropy Technologies, LP More: the full row for Entropy Technologies, LP 4,591 $330K 0.02% new 13F-HR Timeline LPL Financial LLC More: the full row for LPL Financial LLC 4,550 $327K <0.01% new 13F-HR Timeline SEI INVESTMENTS CO in group SEI INVESTMENTS CO More: the full row for SEI INVESTMENTS CO 4,471 $322K <0.01% -5,821 13F-HR Timeline Group OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 4,393 $316K <0.01% -995 13F-HR Timeline Group Seven Fleet Capital Management LP More: the full row for Seven Fleet Capital Management LP 4,300 $309K 0.1% -10,700 13F-HR/A Timeline XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 4,103 $295K 0.01% -3,093 13F-HR Timeline Group FARALLON CAPITAL MANAGEMENT, L.L.C. More: the full row for FARALLON CAPITAL MANAGEMENT, L.L.C. 4,000 $288K <0.01% new 13F-HR Timeline The filing omitted confidential holdings, a later amendment may add them. China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 4,000 $288K 0.02% new 13F-HR Timeline OP Asset Management Ltd More: the full row for OP Asset Management Ltd 3,991 $287K <0.01% new 13F-HR/A Timeline GREAT LAKES ADVISORS, LLC More: the full row for GREAT LAKES ADVISORS, LLC 3,741 $269K <0.01% new 13F-HR Timeline Pictet Asset Management Holding SA in group Pictet Asset Management Holdi… More: the full row for Pictet Asset Management Holding SA 3,718 $268K <0.01% new 13F-HR Timeline Group Orion Porfolio Solutions, LLC More: the full row for Orion Porfolio Solutions, LLC 3,543 $255K <0.01% new 13F-HR Timeline SG Americas Securities, LLC More: the full row for SG Americas Securities, LLC 3,235 $233K <0.01% -7,719 13F-HR Timeline PROFUND ADVISORS LLC More: the full row for PROFUND ADVISORS LLC 3,159 $227K 0.01% new 13F-HR Timeline VICTORY CAPITAL MANAGEMENT INC More: the full row for VICTORY CAPITAL MANAGEMENT INC 3,127 $225K <0.01% new 13F-HR Timeline TEACHER RETIREMENT SYSTEM OF TEXAS More: the full row for TEACHER RETIREMENT SYSTEM OF TEXAS 3,098 $223K <0.01% new 13F-HR Timeline MANGROVE PARTNERS IM, LLC More: the full row for MANGROVE PARTNERS IM, LLC 3,057 $220K 0.02% new 13F-HR Timeline LVW Advisors, LLC More: the full row for LVW Advisors, LLC 3,022 $217K 0.02% new 13F-HR Timeline RAYMOND JAMES FINANCIAL INC in group RAYMOND JAMES FINANCIAL INC More: the full row for RAYMOND JAMES FINANCIAL INC 2,953 $212K <0.01% new 13F-HR Timeline Group Allspring Global Investments Holdings, … in group Allspring Global Investments … More: the full row for Allspring Global Investments Holdings, LLC 2,898 $209K <0.01% new 13F-HR Timeline Group Arrowpoint Investment Partners (Singapo… in group Arrowpoint Investment Partner… More: the full row for Arrowpoint Investment Partners (Singapore) Pte. Ltd. 2,830 $204K 0.3% -2,097 13F-HR Timeline Group Bayforest Capital Ltd More: the full row for Bayforest Capital Ltd 2,538 $183K 0.2% -3 13F-HR Timeline Leonteq Securities AG More: the full row for Leonteq Securities AG 2,000 $144K 0.01% -6,000 13F-HR Timeline ACADIAN ASSET MANAGEMENT LLC in group ACADIAN ASSET MANAGEMENT LLC More: the full row for ACADIAN ASSET MANAGEMENT LLC 1,989 $141K <0.01% -70,252 13F-HR Timeline Group US BANCORP \DE\ in group US BANCORP \DE\ More: the full row for US BANCORP \DE\ 1,916 $138K <0.01% +656 13F-HR Timeline Group Caitong International Asset Management … More: the full row for Caitong International Asset Management Co., Ltd 1,798 $129K 0.02% new 13F-HR Timeline BESSEMER GROUP INC in group BESSEMER GROUP INC More: the full row for BESSEMER GROUP INC 1,565 $112K <0.01% -15 13F-HR Timeline Group Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 1,345 $96.8K <0.01% -4,216 13F-HR Timeline Group Parallel Advisors, LLC More: the full row for Parallel Advisors, LLC 1,053 $75.8K <0.01% new 13F-HR/A Timeline State of Wyoming More: the full row for State of Wyoming 927 $66.7K 0.01% new 13F-HR Timeline KBC Group NV in group KBC Group NV More: the full row for KBC Group NV 721 $52K <0.01% new 13F-HR Timeline Group NATIXIS in group Natixis Investment Managers More: the full row for NATIXIS 685 $49.3K <0.01% 0 13F-HR Timeline Group Allworth Financial LP More: the full row for Allworth Financial LP 681 $49K <0.01% +5 13F-HR Timeline RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 600 $43.2K <0.01% +500 13F-HR Timeline Quantbot Technologies LP More: the full row for Quantbot Technologies LP 417 $30K <0.01% new 13F-HR Timeline BNP PARIBAS ASSET MANAGEMENT Holding S.… in group BNP PARIBAS ASSET MANAGEMENT … More: the full row for BNP PARIBAS ASSET MANAGEMENT Holding S.A. 397 $28.6K <0.01% +219 13F-HR Timeline Group WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 327 $23.5K <0.01% +136 13F-HR/A Timeline Group JONES FINANCIAL COMPANIES LLLP in group JONES FINANCIAL COMPANIES LLLP More: the full row for JONES FINANCIAL COMPANIES LLLP 300 $20.6K <0.01% +191 13F-HR Timeline Group MONTAG A & ASSOCIATES INC More: the full row for MONTAG A & ASSOCIATES INC 250 $18K <0.01% new 13F-HR Timeline KELLEHER FINANCIAL ADVISORS More: the full row for KELLEHER FINANCIAL ADVISORS 200 $14.4K <0.01% new 13F-HR Timeline Activest Wealth Management More: the full row for Activest Wealth Management 200 $14.4K <0.01% 0 13F-HR Timeline CWM, LLC in group CWM, LLC More: the full row for CWM, LLC 176 $12.7K <0.01% -29 13F-HR Timeline Group SBI Securities Co., Ltd. More: the full row for SBI Securities Co., Ltd. 141 $10.1K <0.01% -5 13F-HR Timeline LOS ANGELES CAPITAL MANAGEMENT LLC More: the full row for LOS ANGELES CAPITAL MANAGEMENT LLC 127 $9.14K <0.01% 0 13F-HR Timeline Ascentis Independent Advisors in group Ascentis Wealth Management, L… More: the full row for Ascentis Independent Advisors 120 $8.63K <0.01% new 13F-HR Timeline Group MassMutual Private Wealth & Trust, FSB More: the full row for MassMutual Private Wealth & Trust, FSB 78 $5.61K <0.01% +33 13F-HR Timeline BROWN BROTHERS HARRIMAN & CO in group BROWN BROTHERS HARRIMAN & CO More: the full row for BROWN BROTHERS HARRIMAN & CO 66 $4.75K <0.01% 0 13F-HR Timeline Group MTM Investment Management, LLC More: the full row for MTM Investment Management, LLC 66 $4.75K <0.01% 0 13F-HR Timeline SIGNATUREFD, LLC More: the full row for SIGNATUREFD, LLC 60 $4.32K <0.01% -10 13F-HR Timeline Parkside Financial Bank & Trust More: the full row for Parkside Financial Bank & Trust 52 $3.74K <0.01% new 13F-HR Timeline Rachor Investment Advisory Services, LLC More: the full row for Rachor Investment Advisory Services, LLC 41 $2.95K <0.01% +6 13F-HR Timeline ATLAS CAPITAL ADVISORS INC. More: the full row for ATLAS CAPITAL ADVISORS INC. 40 $2.88K <0.01% 0 13F-HR Timeline Boreal Capital Management LLC More: the full row for Boreal Capital Management LLC 36 $2.59K <0.01% 0 13F-HR Timeline NISA INVESTMENT ADVISORS, LLC More: the full row for NISA INVESTMENT ADVISORS, LLC 20 $1.44K <0.01% 0 13F-HR Timeline Keating Financial Advisory Services, In… More: the full row for Keating Financial Advisory Services, Inc. 18 $1.29K <0.01% -51 13F-HR Timeline Kimelman & Baird, LLC More: the full row for Kimelman & Baird, LLC 13 $936 <0.01% 0 13F-HR Timeline AMERIFLEX GROUP, INC. More: the full row for AMERIFLEX GROUP, INC. 13 $935 <0.01% 0 13F-HR Timeline Medallion Wealth Advisors, LLC More: the full row for Medallion Wealth Advisors, LLC 13 $935 <0.01% 0 13F-HR Timeline GAMMA Investing LLC More: the full row for GAMMA Investing LLC 6 $432 <0.01% new 13F-HR Timeline MAI Capital Management More: the full row for MAI Capital Management 4 $288 <0.01% new 13F-HR Timeline DANSKE BANK A/S More: the full row for DANSKE BANK A/S 2 $144 <0.01% 0 13F-HR Timeline Smartleaf Asset Management LLC More: the full row for Smartleaf Asset Management LLC 2 $130 <0.01% 0 13F-HR Timeline Inspire Investing, LLC in group Inspire Investing, LLC More: the full row for Inspire Investing, LLC 1 $48 <0.01% +1 13F-HR Timeline Group Covestor Ltd More: the full row for Covestor Ltd 0 $0 0% 0 13F-HR Timeline Value filed as zero, left out of ratios. Amount filed as zero, left out of ratios.