MONTANOVA CAPITAL, LLC More: the full row for MONTANOVA CAPITAL, LLC 4,168,970 $263M 7.14% new 13F-HR Timeline SR One Capital Management, LP More: the full row for SR One Capital Management, LP 2,401,868 $152M 16.57% new 13F-HR Timeline CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 1,825,672 $115M 0.08% new 13F-HR Timeline Group FMR LLC in group FMR LLC More: the full row for FMR LLC 1,792,909 $113M 0.01% new 13F-HR Timeline Group VIKING GLOBAL INVESTORS LP in group VIKING GLOBAL INVESTORS LP More: the full row for VIKING GLOBAL INVESTORS LP 1,690,555 $107M 0.3% new 13F-HR Timeline Group Siren, L.L.C. in group Siren, L.L.C. More: the full row for Siren, L.L.C. 1,505,374 $95.1M 2.64% new 13F-HR Timeline Group ADAGE CAPITAL PARTNERS GP, L.L.C. in group ADAGE CAPITAL PARTNERS GP, L.… More: the full row for ADAGE CAPITAL PARTNERS GP, L.L.C. 1,100,000 $69.5M 0.11% new 13F-HR Timeline Group Aberdeen Group plc in group Aberdeen Group plc More: the full row for Aberdeen Group plc 1,054,660 $66.6M 0.11% new 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 976,166 $59.4M <0.01% new 13F-HR/A Timeline Group VANGUARD GROUP INC group of 4 filers holding More: the full row for VANGUARD GROUP INC 808,915 $51.1M new Timeline INFINITUM ASSET MANAGEMENT, LLC More: the full row for INFINITUM ASSET MANAGEMENT, LLC 731,149 $46.2M 5.78% new 13F-HR Timeline MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 654,601 $41.3M 0.04% new 13F-HR Timeline Group Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 532,906 $33.7M 0.07% new 13F-HR Timeline Group Paradigm Biocapital Advisors LP in group Paradigm Biocapital Advisors … More: the full row for Paradigm Biocapital Advisors LP 525,000 $33.2M 0.68% new 13F-HR Timeline Group AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 514,035 $32.5M 0.01% new 13F-HR/A Timeline Group Woodline Partners LP More: the full row for Woodline Partners LP 500,646 $31.6M 0.12% new 13F-HR/A Timeline Deep Track Capital, LP More: the full row for Deep Track Capital, LP 500,000 $31.6M 0.65% new 13F-HR Timeline WELLINGTON MANAGEMENT GROUP LLP in group WELLINGTON MANAGEMENT GROUP L… More: the full row for WELLINGTON MANAGEMENT GROUP LLP 477,833 $30.2M 0.01% new 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 347,075 $21.9M <0.01% new 13F-HR Timeline Group Vivo Capital, LLC More: the full row for Vivo Capital, LLC 300,000 $18.9M 1.57% new 13F-HR/A Timeline STIFEL FINANCIAL CORP in group STIFEL FINANCIAL CORP More: the full row for STIFEL FINANCIAL CORP 294,117 $18.6M 0.02% new 13F-HR Timeline Group BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 282,611 $17.8M <0.01% new 13F-HR Timeline Group EMERALD ADVISERS, LLC group of 2 filers holding More: the full row for EMERALD ADVISERS, LLC 241,819 $15.3M new Timeline FRANKLIN RESOURCES INC in group Franklin Resources More: the full row for FRANKLIN RESOURCES INC 200,000 $12.6M <0.01% new 13F-HR Timeline Group GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 178,206 $11.3M <0.01% new 13F-HR Timeline Group Catalio Capital Management, LP More: the full row for Catalio Capital Management, LP 173,582 $11M 2.29% new 13F-HR Timeline GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 168,975 $10.7M <0.01% new 13F-HR Timeline Group Ensign Peak Advisors, Inc More: the full row for Ensign Peak Advisors, Inc 150,000 $9.47M 0.02% new 13F-HR/A Timeline Kalehua Capital Management LLC More: the full row for Kalehua Capital Management LLC 145,695 $9.2M 6.51% new 13F-HR/A Timeline JENNISON ASSOCIATES LLC More: the full row for JENNISON ASSOCIATES LLC 141,781 $8.95M 0.01% new 13F-HR Timeline D. E. Shaw & Co., Inc. in group D. E. Shaw & Co., Inc. More: the full row for D. E. Shaw & Co., Inc. 134,219 $8.48M 0.01% new 13F-HR Timeline Group MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 123,220 $7.78M 0.01% new 13F-HR Timeline Group MYDA Advisors LLC More: the full row for MYDA Advisors LLC 120,000 $7.58M 1.79% new 13F-HR Timeline Jones Hill Capital LP More: the full row for Jones Hill Capital LP 100,843 $6.37M 1.37% 13F-HR Timeline MASTERS CAPITAL MANAGEMENT LLC More: the full row for MASTERS CAPITAL MANAGEMENT LLC 100,000 $6.32M 0.93% new 13F-HR Timeline CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 98,009 $6.19M <0.01% new 13F-HR Timeline Group SEVEN GRAND MANAGERS, LLC More: the full row for SEVEN GRAND MANAGERS, LLC 74,750 $4.72M 0.32% new 13F-HR Timeline STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 74,400 $4.7M <0.01% new 13F-HR Timeline Group Sofinnova Investments, Inc. More: the full row for Sofinnova Investments, Inc. 73,315 $4.63M 0.23% new 13F-HR Timeline Affinity Asset Advisors, LLC More: the full row for Affinity Asset Advisors, LLC 70,000 $4.42M 0.26% new 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 65,675 $4.15M <0.01% new 13F-HR Timeline Group BAMCO INC /NY/ in group Baron Capital More: the full row for BAMCO INC /NY/ 59,668 $3.77M 0.01% new 13F-HR Timeline Group MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 51,690 $3.26M <0.01% new 13F-HR Timeline Group Monashee Investment Management LLC More: the full row for Monashee Investment Management LLC 50,000 $3.16M 1.72% new 13F-HR Timeline Polymer Capital Management (HK) LTD More: the full row for Polymer Capital Management (HK) LTD 41,296 $2.61M 0.37% new 13F-HR Timeline BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 36,911 $2.33M <0.01% new 13F-HR Timeline Group NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 34,537 $2.18M <0.01% new 13F-HR Timeline Group Brevan Howard Capital Management LP in group Brevan Howard Capital Managem… More: the full row for Brevan Howard Capital Management LP 30,082 $1.9M 0.02% new 13F-HR Timeline Group Logos Global Management LP More: the full row for Logos Global Management LP 25,000 $1.58M 0.08% new 13F-HR Timeline Centiva Capital, LP More: the full row for Centiva Capital, LP 20,000 $1.26M 0.06% new 13F-HR Timeline FIRST TRUST ADVISORS LP in group FIRST TRUST ADVISORS LP More: the full row for FIRST TRUST ADVISORS LP 19,775 $1.25M <0.01% new 13F-HR Timeline Group Shay Capital LLC More: the full row for Shay Capital LLC 18,000 $1.14M 0.16% new 13F-HR Timeline Squarepoint Ops LLC in group Squarepoint Ops LLC More: the full row for Squarepoint Ops LLC 16,610 $1.05M <0.01% new 13F-HR Timeline Group Penserra Capital Management LLC in group Penserra Capital Management L… More: the full row for Penserra Capital Management LLC 14,700 $928K 0.01% new 13F-HR Timeline Group FORMULA GROWTH LTD More: the full row for FORMULA GROWTH LTD 14,000 $884K 0.4% new 13F-HR Timeline TORONTO DOMINION BANK in group TORONTO DOMINION BANK More: the full row for TORONTO DOMINION BANK 13,428 $848K <0.01% new 13F-HR Timeline Group CIBC Bancorp USA Inc. in group CIBC Bancorp USA Inc. More: the full row for CIBC Bancorp USA Inc. 13,100 $827K <0.01% 13F-HR Timeline Group XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 11,510 $727K 0.01% new 13F-HR Timeline Group Hudson Bay Capital Management LP in group Hudson Bay Capital Management… More: the full row for Hudson Bay Capital Management LP 11,079 $700K <0.01% new 13F-HR Timeline Group CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 10,691 $675K <0.01% new 13F-HR Timeline Group Persistent Asset Partners Ltd More: the full row for Persistent Asset Partners Ltd 9,191 $580K 0.23% new 13F-HR Timeline Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 7,105 $449K <0.01% new 13F-HR Timeline Group LANDSCAPE CAPITAL MANAGEMENT, L.L.C. in group LANDSCAPE CAPITAL MANAGEMENT,… More: the full row for LANDSCAPE CAPITAL MANAGEMENT, L.L.C. 6,711 $424K 0.03% new 13F-HR Timeline Group DEERFIELD MANAGEMENT COMPANY, L.P. in group DEERFIELD MANAGEMENT COMPANY,… More: the full row for DEERFIELD MANAGEMENT COMPANY, L.P. 5,000 $316K <0.01% new 13F-HR Timeline Group Private Advisor Group, LLC More: the full row for Private Advisor Group, LLC 5,000 $316K <0.01% new 13F-HR Timeline Ghisallo Capital Management LLC More: the full row for Ghisallo Capital Management LLC 5,000 $316K 0.01% new 13F-HR Timeline Burkehill Global Management, LP More: the full row for Burkehill Global Management, LP 5,000 $316K 0.02% new 13F-HR Timeline Schonfeld Strategic Advisors LLC More: the full row for Schonfeld Strategic Advisors LLC 3,900 $246K <0.01% new 13F-HR Timeline Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 3,668 $232K <0.01% new 13F-HR Timeline Group ExodusPoint Capital Management, LP More: the full row for ExodusPoint Capital Management, LP 3,358 $212K <0.01% new 13F-HR Timeline US BANCORP \DE\ in group US BANCORP \DE\ More: the full row for US BANCORP \DE\ 470 $29.7K <0.01% new 13F-HR Timeline Group Allworth Financial LP More: the full row for Allworth Financial LP 50 $3.16K <0.01% new 13F-HR Timeline NVWM, LLC More: the full row for NVWM, LLC 35 $2.21K <0.01% new 13F-HR Timeline SBI Securities Co., Ltd. More: the full row for SBI Securities Co., Ltd. 20 $1.26K <0.01% new 13F-HR Timeline ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 8 $1K <0.01% new 13F-HR Timeline Group JONES FINANCIAL COMPANIES LLLP in group JONES FINANCIAL COMPANIES LLLP More: the full row for JONES FINANCIAL COMPANIES LLLP 10 $655 <0.01% new 13F-HR Timeline Group Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 10 $632 <0.01% new 13F-HR Timeline Group