Lynx1 Capital Management LP in group Lynx1 Capital Management LP More: the full row for Lynx1 Capital Management LP 10,406,575 $132M 26.75% +1,805,386 13F-HR Timeline Group BVF INC/IL in group BVF INC/IL More: the full row for BVF INC/IL 8,827,712 $112M 3.77% 0 13F-HR Timeline Group RA CAPITAL MANAGEMENT, L.P. in group RA CAPITAL MANAGEMENT, L.P. More: the full row for RA CAPITAL MANAGEMENT, L.P. 7,676,697 $97.5M 1% 0 13F-HR Timeline Group RTW INVESTMENTS, LP More: the full row for RTW INVESTMENTS, LP 5,933,815 $75.4M 0.75% +364,251 13F-HR Timeline FMR LLC in group FMR LLC More: the full row for FMR LLC 5,136,045 $65.2M <0.01% -191,000 13F-HR Timeline Group Avoro Capital Advisors LLC More: the full row for Avoro Capital Advisors LLC 1,800,000 $22.9M 0.22% new 13F-HR/A Timeline Cormorant Asset Management, LP More: the full row for Cormorant Asset Management, LP 1,300,000 $16.5M 0.94% -616,439 13F-HR Timeline Jefferies Financial Group Inc. in group Jefferies Financial Group Inc. More: the full row for Jefferies Financial Group Inc. 712,300 $9.05M 0.07% +2,988 13F-HR Timeline Group Verition Fund Management LLC More: the full row for Verition Fund Management LLC 673,735 $8.56M 0.05% -4,754 13F-HR Timeline 5AM Venture Management, LLC More: the full row for 5AM Venture Management, LLC 572,665 $7.27M 2.29% 0 13F-HR Timeline BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 434,401 $5.52M <0.01% +376,542 13F-HR Timeline Group Troluce Capital Advisors LLC More: the full row for Troluce Capital Advisors LLC 373,212 $4.74M 3.5% +326,490 13F-HR Timeline UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 363,381 $4.61M <0.01% -148,083 13F-HR Timeline Group Squadron Capital Management LLC More: the full row for Squadron Capital Management LLC 315,000 $4M 1.79% 13F-HR Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 295,926 $3.76M <0.01% -567,676 13F-HR Timeline Group CenterBook Partners LP More: the full row for CenterBook Partners LP 283,441 $3.6M 0.18% +117,288 13F-HR Timeline MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 240,764 $3.06M <0.01% +71,264 13F-HR Timeline Group HighVista Strategies LLC More: the full row for HighVista Strategies LLC 240,524 $3.05M 0.79% -1,370 13F-HR Timeline Alyeska Investment Group, L.P. in group Alyeska Investment Group, L.P. More: the full row for Alyeska Investment Group, L.P. 204,975 $2.6M 0.01% 0 13F-HR Timeline Group BOOTHBAY FUND MANAGEMENT, LLC More: the full row for BOOTHBAY FUND MANAGEMENT, LLC 112,184 $1.42M 0.04% +28,634 13F-HR Timeline GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 80,986 $1.03M <0.01% +69,911 13F-HR/A Timeline Group AdvisorShares Investments LLC More: the full row for AdvisorShares Investments LLC 67,112 $852K 0.14% +13,121 13F-HR Timeline Trexquant Investment LP More: the full row for Trexquant Investment LP 54,776 $696K 0.01% new 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 51,404 $653K <0.01% +47,162 13F-HR/A Timeline Group JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 50,005 $635K <0.01% +27,001 13F-HR Timeline Group BIT Capital GmbH More: the full row for BIT Capital GmbH 50,000 $635K 0.03% new 13F-HR Timeline XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 44,446 $564K 0.01% new 13F-HR Timeline Group GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 35,645 $453K <0.01% 0 13F-HR Timeline Group NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 32,828 $417K <0.01% -145 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 26,258 $333K <0.01% -68,144 13F-HR Timeline Group Virtus Investment Advisers, LLC in group Virtus Investment Advisers, L… More: the full row for Virtus Investment Advisers, LLC 20,408 $259K 0.07% +11,539 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 18,881 $240K <0.01% +4,981 13F-HR Timeline Group GSA CAPITAL PARTNERS LLP More: the full row for GSA CAPITAL PARTNERS LLP 18,565 $236K 0.02% new 13F-HR Timeline HRT FINANCIAL LP More: the full row for HRT FINANCIAL LP 15,936 $202K <0.01% new 13F-HR Timeline SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 15,877 $202K <0.01% new 13F-HR Timeline Group HighTower Advisors, LLC More: the full row for HighTower Advisors, LLC 15,600 $198K <0.01% -500 13F-HR Timeline STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 10,821 $137K <0.01% -171 13F-HR Timeline Group Lion Point Capital, LP More: the full row for Lion Point Capital, LP 10,200 $130K 0.67% new 13F-HR Timeline China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 10,107 $128K 0.01% new 13F-HR Timeline OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 10,025 $127K <0.01% -100 13F-HR Timeline Group BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 4,450 $56.5K <0.01% +4,175 13F-HR Timeline Group CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 4,404 $55.9K <0.01% +4,373 13F-HR Timeline Group Mirae Asset Global Investments Co., Ltd. in group Mirae Asset Global Investment… More: the full row for Mirae Asset Global Investments Co., Ltd. 3,014 $38.3K <0.01% new 13F-HR Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 2,118 $26.9K <0.01% +822 13F-HR Timeline Group ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 1,810 $23K <0.01% +52 13F-HR Timeline Group BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 1,337 $17K <0.01% -4,865 13F-HR Timeline Group WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 1,250 $15.9K <0.01% 0 13F-HR Timeline Group GF FUND MANAGEMENT CO. LTD. More: the full row for GF FUND MANAGEMENT CO. LTD. 1,218 $15.5K <0.01% new 13F-HR Timeline Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 770 $9.78K <0.01% new 13F-HR Timeline Group Global Retirement Partners, LLC More: the full row for Global Retirement Partners, LLC 400 $5.08K <0.01% -400 13F-HR Timeline Daiwa Securities Group Inc. in group Daiwa Securities Group Inc. More: the full row for Daiwa Securities Group Inc. 207 $3K <0.01% new 13F-HR Timeline Group SIMPLEX TRADING, LLC More: the full row for SIMPLEX TRADING, LLC 48 $609 <0.01% -4,161 13F-HR Timeline SBI Securities Co., Ltd. More: the full row for SBI Securities Co., Ltd. 20 $254 <0.01% new 13F-HR Timeline