13F-HR filed by 5AM Venture Management, LLC
5AM Venture Management, LLC filed this 13F-HR for the quarter ended 2025-12-31, filed 2026-02-17, with 21 holding rows worth $318,102,880.
- Accession
- 0001799883-26-000001
- Filer
- CIK 1799883
- Filed
- 2026-02-17
- Accepted by EDGAR
- acceptance time not in the bulk data set
- Ingested
- Source
- SEC quarterly data set
13F report for Q4 2025
A holdings report, 21 entries on the cover page, a total value of $318,102,880 stated on the cover page (in dollars after the unit check, H1), rows summing to $318,102,880 with VALUE read as dollars as filed, 13F file number 028-19757. The quarter's positions are built on this report. The resolved quarter.
The information table after summing rows of one CUSIP and put or call (H4), with the CUSIP and issuer name as filed. Values in dollars after the unit check (method).
| Issuer as filed | CUSIP | Class | Amount | Value | Value read as | Type |
|---|---|---|---|---|---|---|
| ENTRADA THERAPEUTICS INC COM | 29384C108 | Stock | 4,056,379 | $41,699,576 | dollars as filed | |
| CAMP4 THERAPEUTICS CORP | 13463J101 | COM | 5,869,091 | $35,977,528 | dollars as filed | |
| TYRA BIOSCIENCES INC | 90240B106 | COMMON STOCK | 1,029,298 | $27,060,244 | dollars as filed | |
| VIRIDIAN THERAPEUTICS INC | 92790C104 | COM | 736,595 | $22,922,836 | dollars as filed | |
| PHARVARIS NV | N69605108 | COMMON STOCK | 797,600 | $22,133,400 | dollars as filed | |
| ERASCA INC COM | 29479A108 | Stock | 5,405,404 | $20,108,103 | dollars as filed | |
| EYEPOINT INC COM NEW | 30233G209 | Stock | 1,050,000 | $19,183,500 | dollars as filed | |
| MAPLIGHT THERAPEUTICS INC | 56565P103 | COMMON STOCK | 950,011 | $16,686,943 | dollars as filed | |
| CENTESSA PHARMACEUTICALS PLC | 152309100 | SPONSORED ADS | 580,945 | $14,529,434 | dollars as filed | |
| CELLDEX THERAPEUTICS INC NEW | 15117B202 | COM NEW | 497,270 | $13,505,853 | dollars as filed | |
| TECTONIC THERAPEUTIC INC | 878972108 | COMMON STOCK | 606,660 | $12,654,928 | dollars as filed | |
| ENLIVEN THERAPEUTICS INC COM | 29337E102 | Stock | 772,477 | $11,896,146 | dollars as filed | |
| ARTIVA BIOTHERAPEUTICS INC | 04317A107 | COM | 2,353,304 | $10,095,674 | dollars as filed | |
| SURROZEN INC | 86889P208 | COMMON STOCK | 387,500 | $8,757,500 | dollars as filed | |
| BIOHAVEN LTD | G1110E107 | COM | 738,972 | $8,342,994 | dollars as filed | |
| PROTARA THERAPEUTICS INC | 74365U107 | COM STK | 1,369,782 | $7,300,938 | dollars as filed | |
| GH RESEARCH PLC ORDINARY SHARES | G3855L106 | Stock | 572,665 | $7,272,846 | dollars as filed | |
| SKYE BIOSCIENCE INC | 83086J200 | COM NEW | 9,681,763 | $7,258,418 | dollars as filed | |
| ZENTALIS PHARMACEUTICALS INC | 98943L107 | COMMON STOCK | 3,947,913 | $5,329,683 | dollars as filed | |
| SILENCE THERAPEUTICS PLC | 82686Q101 | ADS | 476,200 | $2,895,296 | dollars as filed | |
| RALLYBIO CORP | 75120L100 | COM | 3,630,724 | $2,491,040 | dollars as filed |
Amendment chain
| Filing | Role | Filed | Accepted | Ingested |
|---|---|---|---|---|
| 13F-HR 0001799883-26-000001 | this filing | 2026-02-17 | acceptance time not in the bulk data set |